Dr Sara Trujillo Munoz

  • Research Assistant (Biomedical Engineering)

Research interests

My current research pursues to engineer microenvironments for the efficient presentation of growth factors for bone regeneration, with application in veterinary patients. My position in this grant involves continuous and close collaboration with clinicians to develop a safe and efficient bone graft for canine patients. 

In addition, I work on the development of synthetic hydrogel biomaterials that contain full-length proteins from the extracellular matrix, to exploit certain aspects of the natural cell microenvironment but with further control over biophysical properties such as stiffness and degradability. 

My research interests include the design and fabrication of novel hydrogel biomaterials to mimic the extracellular matrix in physiological or pathological conditions to be used in regenerative medicine and also to understand the cellular mechanisms that lead to disease. 


Publications

List by: Type | Date

Jump to: 2019 | 2017 | 2016 | 2015 | 2014
Number of items: 9.

2019

Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi:10.1016/B978-0-12-801238-3.11141-9)

2017

Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi:10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)

2016

Trujillo, S. , Lizundia, E., Vilas, J. L. and Salmeron-Sanchez, M. (2016) PLLA/ZnO nanocomposites: dynamic surfaces to harness cell differentiation. Colloids and Surfaces B: Biointerfaces, 144, pp. 152-160. (doi:10.1016/j.colsurfb.2016.04.007)

2015

Trujillo, S. , Pérez-Román, E., Kyritsis, A., Gómez Ribelles, J. L. and Pandis, C. (2015) Organic-inorganic bonding in chitosan-silica hybrid networks: physical properties. Journal of Polymer Science Part B: Polymer Physics, 53(19), pp. 1391-1400. (doi:10.1002/polb.23774)

Pandis, C., Trujillo, S. , Matos, J., Madeira, S., Ródenas-Rochina, J., Kripotou, S., Kyritsis, A., Mano, J. F. and Gómez Ribelles, J. L. (2015) Porous polylactic acid-silica hybrids: preparation, characterization, and study of mesenchymal stem cell osteogenic differentiation. Macromolecular Bioscience, 15(2), pp. 262-274. (doi:10.1002/mabi.201400339) (PMID:25303745)

2014

Demirdögen, B., Plazas Bonilla, C. E., Trujillo., S. , Perilla, J. E., Elcin, A. E., Elcin, Y. M. and Gómez Ribelles, J. L. (2014) Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering. Journal of Biomedical Materials Research Part A, 102(9), pp. 3229-3236. (doi:10.1002/jbm.a.34999) (PMID:24167153)

Pandis, C., Trujillo, S. , Roganowicz, M. and Gómez Ribelles, J. L. (2014) Hybrid polycaprolactone/silica porous membranes produced by sol-gel. Macromolecular Symposia, 341(1), pp. 34-44. (doi:10.1002/masy.201300155)

Plazas Bonilla, C. E., Trujillo, S. , Demirdögen, B., Perilla, J. E., Murat Elcin, Y. and Gómez Ribelles, J. L. (2014) New porous polycaprolactone–silica composites for bone regeneration. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 40, pp. 418-426. (doi:10.1016/j.msec.2014.04.024) (PMID:24857510)

Trujillo, S. , Plazas Bonilla, C. E., Santos, M. S., Matos, J. M., Gamboa, T., Perilla, J. E., Mano, J. F. and Gómez Ribelles, J. L. (2014) Polycaprolactone membranes reinforced by toughened sol–gel produced silica networks. Journal of Sol-Gel Science and Technology, 71(1), pp. 136-146. (doi:10.1007/s10971-014-3342-4)

This list was generated on Thu Nov 14 02:05:20 2019 GMT.
Number of items: 9.

Articles

Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi:10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)

Trujillo, S. , Lizundia, E., Vilas, J. L. and Salmeron-Sanchez, M. (2016) PLLA/ZnO nanocomposites: dynamic surfaces to harness cell differentiation. Colloids and Surfaces B: Biointerfaces, 144, pp. 152-160. (doi:10.1016/j.colsurfb.2016.04.007)

Trujillo, S. , Pérez-Román, E., Kyritsis, A., Gómez Ribelles, J. L. and Pandis, C. (2015) Organic-inorganic bonding in chitosan-silica hybrid networks: physical properties. Journal of Polymer Science Part B: Polymer Physics, 53(19), pp. 1391-1400. (doi:10.1002/polb.23774)

Pandis, C., Trujillo, S. , Matos, J., Madeira, S., Ródenas-Rochina, J., Kripotou, S., Kyritsis, A., Mano, J. F. and Gómez Ribelles, J. L. (2015) Porous polylactic acid-silica hybrids: preparation, characterization, and study of mesenchymal stem cell osteogenic differentiation. Macromolecular Bioscience, 15(2), pp. 262-274. (doi:10.1002/mabi.201400339) (PMID:25303745)

Demirdögen, B., Plazas Bonilla, C. E., Trujillo., S. , Perilla, J. E., Elcin, A. E., Elcin, Y. M. and Gómez Ribelles, J. L. (2014) Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering. Journal of Biomedical Materials Research Part A, 102(9), pp. 3229-3236. (doi:10.1002/jbm.a.34999) (PMID:24167153)

Pandis, C., Trujillo, S. , Roganowicz, M. and Gómez Ribelles, J. L. (2014) Hybrid polycaprolactone/silica porous membranes produced by sol-gel. Macromolecular Symposia, 341(1), pp. 34-44. (doi:10.1002/masy.201300155)

Plazas Bonilla, C. E., Trujillo, S. , Demirdögen, B., Perilla, J. E., Murat Elcin, Y. and Gómez Ribelles, J. L. (2014) New porous polycaprolactone–silica composites for bone regeneration. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 40, pp. 418-426. (doi:10.1016/j.msec.2014.04.024) (PMID:24857510)

Trujillo, S. , Plazas Bonilla, C. E., Santos, M. S., Matos, J. M., Gamboa, T., Perilla, J. E., Mano, J. F. and Gómez Ribelles, J. L. (2014) Polycaprolactone membranes reinforced by toughened sol–gel produced silica networks. Journal of Sol-Gel Science and Technology, 71(1), pp. 136-146. (doi:10.1007/s10971-014-3342-4)

Book Sections

Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi:10.1016/B978-0-12-801238-3.11141-9)

This list was generated on Thu Nov 14 02:05:20 2019 GMT.

Grants

“Development of new bioinks for the efficient presentation of growth factors for tissue engineering applications.” EPSRC IAA, co-applicant, £10.5k.

Mobility funding 2016, £2.5k (Internal mobility fund in the James Watt School of Engineering) to cover expenses during a secondment at the University of Pennsylvania (United States).

James Watt Studentship (doctoral scholarship), "Engineering fibronectin-based hydrogels as novel three-dimensional microenvironments to promote microvasculature growth", 2014-2018, £66k.