Dr Melanie Jimenez

  • Research Associate (Biomedical Engineering)

Research interests

Research Interests

My research spans disciplines, at the interface of engineering, physics and biology. My research interests include:

  • Microfluidics
  • Sample processing
  • Particle/cell separation
  • Biomedical engineering/medical diagnostics
  • Bubbles
  • Water engineering 

For further information: Google Scholar, Personal website, Twitter

Short Biosketch

  • I received an Eng. degree in chemical/process engineering from the ENSIACET engineering school (Toulouse, France), and a M.Sc. degree in Process Engineering and Environment from the National Polytechnic Institute of Toulouse, both in September 2010.
  • I achieved my Ph.D. within the BioSystems and Process Engineering Laboratory (France) and received a Ph.D. degree in 2013. During my Ph.D. thesis I worked in collaboration with SUEZ on new optical methods for characterizing mass transfer and hydrodynamic behaviors during aeration of wastewaters. 
  • From 2014 until June 2016, I joined Heriot-Watt University (Edinburgh, UK) within the Institute of Biological chemistry, Biophysics and Bioengineering (IB3). I was part of the EU AQUAVALENS project to develop label-free microfluidic devices for isolating pathogens from drinking water. 
  • From July 2016 until February 2016, I extended this microfluidic approach to the purification of manufactured red blood cells from STEM cells. 
  • Since February 2016, I work in Jon Cooper's group on advanced, low-cost and reliable medical diagnostics using microsystems. 

Grants

Research Funding

Collaborative Funding (PI), EPSRC Physics of Life Network (2015)

Two-day workshop to promote new collaborations at the interface of biology and physical sciences with international leaders

Heriot-Watt EPSRC Impact Acceleration Award (co-I) (2015)                            

Development of new microfluidic tools for purifying manufactured red blood cells from STEM cells

Doctoral Fellowship (PI), French ministry of Higher Education (2010-2013)                    

Supporting top students to pursue with a Ph.D. thesis

Grant (co-I), funded by international company SUEZ (2010-2013)

Consumables and travels to international conferences/collaborations

Travel grant (PI), University of Toulouse (2009)

Supporting top 5% students to spend a semester in a foreign university

Merit scholarship (PI), French region Languedoc-Roussillon (2005-2009)

Supporting top 2% students to pursue post-graduate studies


Supervision

I am mentoring/mentored the following Ph.D. students:

  • Ewa Guzniczack, Heriot-Watt University (2015-…) Microfluidics for STEM cell purification
  • Anusha Keloth, Heriot-Watt University (2015-…) Optofluidics for rare marine cell isolation
  • Dr Brian Miller, University of Edinburgh (2014-2015) Large scale microfluidics for high throughput particle separation

Teaching

Teaching assistant in fluid mechanics, thermodynamics, mass transfer and chemistry


Additional information

Awards, distinctions

  • Invited to SET for BRITAIN 2016-Engineering
  • SULSA prize for the best video about the importance of light in research (IOP video competition) (2015)
  • Wellcome Trust "Frontiers Innovator" Award for talented and ambitious junior researchers looking to perform original interdisciplinary research (2015)
  • Top papers  "Innovation" session at international GLS12 conference (New-York, July 2015)
  • Heriot-Watt Public Engagement 2015 prize in the category “Team award” (2015)
  • Best microfluidic design award, RAEng Ingenious Scheme (2015)

Memberships


Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2010
Number of items: 19.

2017

Guzniczak, E., Mohammad Zadeh, M., Dempsey, F., Jimenez, M. , Bock, H., Whyte, G., Willoughby, N. and Bridle, H. (2017) High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing. Scientific Reports, 7, 14457. (doi:10.1038/s41598-017-14958-w) (PMID:29089557) (PMCID:PMC5663858)

Xu, F., Jimenez, M. , Dietrich, N. and Hébrard, G. (2017) Fast determination of gas-liquid diffusion coefficient by an innovative double approach. Chemical Engineering Science, 170, pp. 68-76. (doi:10.1016/j.ces.2017.02.043)

Jimenez, M. , Miller, B. and Bridle, H. L. (2017) Efficient separation of small microparticles at high flowrates using spiral channels: Application to waterborne pathogens. Chemical Engineering Science, 157, pp. 247-254. (doi:10.1016/j.ces.2015.08.042)

Keloth, A., Jimenez, M. , Kar, A. and Paterson, L. (2017) Particle Manipulation within an Ultrafast Laser Inscribed Optofluidic Device. In: Optical Trapping Applications 2017, San Diego, CA, USA, 2-5 April 2017, OtW2E.3. (doi:10.1364/OTA.2017.OtW2E.3)

Miller, B., Jimenez, M. and Bridle, H. (2017) Cascading and parallelising curvilinear inertial focusing systems for high volume, wide size distribution, separation and concentration of particles. Scientific Reports, 6(1), 36386. (doi:10.1038/srep36386) (PMID:27808244) (PMCID:PMC5093461)

2016

Jimenez, M. and Bridle, H. (2016) Microfluidics for effective concentration and sorting of waterborne protozoan pathogens. Journal of Microbiological Methods, 126, pp. 8-11. (doi:10.1016/j.mimet.2016.04.008) (PMID:27074367)

Gray, B. L., Becker, H., Keloth, A., Jimenez, M. , Bridle, H., Paterson, L., Markx, G. H. and Kar, A. K. (2016) Femtosecond Laser Fabricated Integrated Chip for Manipulation of Single Cells. SPIE BIOS 2016, San Francisco, CA, USA, 13-18 Feb 2016. 97050K. (doi:10.1117/12.2212719)

2015

McKenna, I., Tonolini, F., Tobin, R., Houssineau, J., Bridle, H., McDougall, C., Schlangen, I., McGrath, J. S., Jimenez, M. and Clark, D. E. (2015) Observing the Dynamics of Waterborne Pathogens for Assessing the Level of Contamination. In: Sensor Signal Processing for Defence (SSPD), Edinburgh, UK, 9-10 Sept 2015, pp. 1-5. ISBN 9781479974443 (doi:10.1109/SSPD.2015.7288514)

Dietrich, N., Francois, J., Jimenez, M. , Cockx, A., Guiraud, P. and Hébrard, G. (2015) Fast measurements of the gas-liquid diffusion coefficient in the Gaussian wake of a spherical bubble. Chemical Engineering and Technology, 38(5), pp. 941-946. (doi:10.1002/ceat.201400471)

Jimenez, M. and Bridle, H. L. (2015) Angry pathogens, how to get rid of them: introducing microfluidics for waterborne pathogen separation to children. Lab on a Chip, 15(4), pp. 947-957. (doi:10.1039/c4lc00944d) (PMID:25435144)

2014

Jimenez, M. , Dietrich, N., Grace, J. R. and Hébrard, G. (2014) Oxygen mass transfer and hydrodynamic behaviour in wastewater: Determination of local impact of surfactants by visualization techniques. Water Research, 58, pp. 111-121. (doi:10.1016/j.watres.2014.03.065) (PMID:24747142)

McGrath, J., Jimenez, M. and Bridle, H. (2014) Deterministic lateral displacement for particle separation: a review. Lab on a Chip, 14(21), pp. 4139-4158. (doi:10.1039/C4LC00939H)

2013

Dietrich, N., Loubière, K., Jimenez, M. , Hébrard, G. and Gourdon, C. (2013) A new direct technique for visualizing and measuring gas–liquid mass transfer around bubbles moving in a straight millimetric square channel. Chemical Engineering Science, 100, pp. 172-182. (doi:10.1016/j.ces.2013.03.041)

Jimenez, M. , Dietrich, N. and Hébrard, G. (2013) Mass transfer in the wake of non-spherical air bubbles quantified by quenching of fluorescence. Chemical Engineering Science, 100, pp. 160-171. (doi:10.1016/j.ces.2013.01.036)

Kherbeche, A., Milnes, J., Jimenez, M. , Dietrich, N., Hébrard, G. and Lekhlif, B. (2013) Multi-scale analysis of the influence of physicochemical parameters on the hydrodynamic and gas–liquid mass transfer in gas/liquid/solid reactors. Chemical Engineering Science, 100, pp. 515-528. (doi:10.1016/j.ces.2013.06.025)

Jimenez, M. , Dietrich, N., Cockx, A. and Hébrard, G. (2013) Experimental study of O2 diffusion coefficient measurement at a planar gas-liquid interface by planar laser-induced fluorescence with inhibition. AIChE Journal, 59(1), pp. 325-333. (doi:10.1002/aic.13805)

2012

Jimenez, M. , Dietrich, N. and Hebrard, G. (2012) A new method for measuring diffusion coefficient of gases in liquids by PLIF. Modern Physics Letters B, 26(06), 1150034. (doi:10.1142/S0217984911500345)

2010

de Gracia, A., Rincón, L., Castell, A., Jimenez, M. , Boer, D., Medrano, M. and Cabeza, L. F. (2010) Life cycle assessment of the inclusion of phase change materials (PCM) in experimental buildings. Energy and Buildings, 42(9), pp. 1517-1523. (doi:10.1016/j.enbuild.2010.03.022)

Gebreslassie, B., Jimenez, M. , Guillen-Gosalbez, G., Jimenez, L. and Boer, D. (2010) Multi-objective optimization of solar assisted absorption cooling system. In: Pierucci, S. (ed.) 20th European Symposium of Computer Aided Process Engineering. Series: Computer-aided chemical engineering (28). Elsevier: Amsterdam, pp. 1033-1038. ISBN 9780444535696

This list was generated on Thu Nov 23 16:31:55 2017 GMT.
Number of items: 19.

Articles

Guzniczak, E., Mohammad Zadeh, M., Dempsey, F., Jimenez, M. , Bock, H., Whyte, G., Willoughby, N. and Bridle, H. (2017) High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing. Scientific Reports, 7, 14457. (doi:10.1038/s41598-017-14958-w) (PMID:29089557) (PMCID:PMC5663858)

Xu, F., Jimenez, M. , Dietrich, N. and Hébrard, G. (2017) Fast determination of gas-liquid diffusion coefficient by an innovative double approach. Chemical Engineering Science, 170, pp. 68-76. (doi:10.1016/j.ces.2017.02.043)

Jimenez, M. , Miller, B. and Bridle, H. L. (2017) Efficient separation of small microparticles at high flowrates using spiral channels: Application to waterborne pathogens. Chemical Engineering Science, 157, pp. 247-254. (doi:10.1016/j.ces.2015.08.042)

Miller, B., Jimenez, M. and Bridle, H. (2017) Cascading and parallelising curvilinear inertial focusing systems for high volume, wide size distribution, separation and concentration of particles. Scientific Reports, 6(1), 36386. (doi:10.1038/srep36386) (PMID:27808244) (PMCID:PMC5093461)

Jimenez, M. and Bridle, H. (2016) Microfluidics for effective concentration and sorting of waterborne protozoan pathogens. Journal of Microbiological Methods, 126, pp. 8-11. (doi:10.1016/j.mimet.2016.04.008) (PMID:27074367)

Dietrich, N., Francois, J., Jimenez, M. , Cockx, A., Guiraud, P. and Hébrard, G. (2015) Fast measurements of the gas-liquid diffusion coefficient in the Gaussian wake of a spherical bubble. Chemical Engineering and Technology, 38(5), pp. 941-946. (doi:10.1002/ceat.201400471)

Jimenez, M. and Bridle, H. L. (2015) Angry pathogens, how to get rid of them: introducing microfluidics for waterborne pathogen separation to children. Lab on a Chip, 15(4), pp. 947-957. (doi:10.1039/c4lc00944d) (PMID:25435144)

Jimenez, M. , Dietrich, N., Grace, J. R. and Hébrard, G. (2014) Oxygen mass transfer and hydrodynamic behaviour in wastewater: Determination of local impact of surfactants by visualization techniques. Water Research, 58, pp. 111-121. (doi:10.1016/j.watres.2014.03.065) (PMID:24747142)

McGrath, J., Jimenez, M. and Bridle, H. (2014) Deterministic lateral displacement for particle separation: a review. Lab on a Chip, 14(21), pp. 4139-4158. (doi:10.1039/C4LC00939H)

Dietrich, N., Loubière, K., Jimenez, M. , Hébrard, G. and Gourdon, C. (2013) A new direct technique for visualizing and measuring gas–liquid mass transfer around bubbles moving in a straight millimetric square channel. Chemical Engineering Science, 100, pp. 172-182. (doi:10.1016/j.ces.2013.03.041)

Jimenez, M. , Dietrich, N. and Hébrard, G. (2013) Mass transfer in the wake of non-spherical air bubbles quantified by quenching of fluorescence. Chemical Engineering Science, 100, pp. 160-171. (doi:10.1016/j.ces.2013.01.036)

Kherbeche, A., Milnes, J., Jimenez, M. , Dietrich, N., Hébrard, G. and Lekhlif, B. (2013) Multi-scale analysis of the influence of physicochemical parameters on the hydrodynamic and gas–liquid mass transfer in gas/liquid/solid reactors. Chemical Engineering Science, 100, pp. 515-528. (doi:10.1016/j.ces.2013.06.025)

Jimenez, M. , Dietrich, N., Cockx, A. and Hébrard, G. (2013) Experimental study of O2 diffusion coefficient measurement at a planar gas-liquid interface by planar laser-induced fluorescence with inhibition. AIChE Journal, 59(1), pp. 325-333. (doi:10.1002/aic.13805)

Jimenez, M. , Dietrich, N. and Hebrard, G. (2012) A new method for measuring diffusion coefficient of gases in liquids by PLIF. Modern Physics Letters B, 26(06), 1150034. (doi:10.1142/S0217984911500345)

de Gracia, A., Rincón, L., Castell, A., Jimenez, M. , Boer, D., Medrano, M. and Cabeza, L. F. (2010) Life cycle assessment of the inclusion of phase change materials (PCM) in experimental buildings. Energy and Buildings, 42(9), pp. 1517-1523. (doi:10.1016/j.enbuild.2010.03.022)

Book Sections

Gebreslassie, B., Jimenez, M. , Guillen-Gosalbez, G., Jimenez, L. and Boer, D. (2010) Multi-objective optimization of solar assisted absorption cooling system. In: Pierucci, S. (ed.) 20th European Symposium of Computer Aided Process Engineering. Series: Computer-aided chemical engineering (28). Elsevier: Amsterdam, pp. 1033-1038. ISBN 9780444535696

Conference or Workshop Item

Gray, B. L., Becker, H., Keloth, A., Jimenez, M. , Bridle, H., Paterson, L., Markx, G. H. and Kar, A. K. (2016) Femtosecond Laser Fabricated Integrated Chip for Manipulation of Single Cells. SPIE BIOS 2016, San Francisco, CA, USA, 13-18 Feb 2016. 97050K. (doi:10.1117/12.2212719)

Conference Proceedings

Keloth, A., Jimenez, M. , Kar, A. and Paterson, L. (2017) Particle Manipulation within an Ultrafast Laser Inscribed Optofluidic Device. In: Optical Trapping Applications 2017, San Diego, CA, USA, 2-5 April 2017, OtW2E.3. (doi:10.1364/OTA.2017.OtW2E.3)

McKenna, I., Tonolini, F., Tobin, R., Houssineau, J., Bridle, H., McDougall, C., Schlangen, I., McGrath, J. S., Jimenez, M. and Clark, D. E. (2015) Observing the Dynamics of Waterborne Pathogens for Assessing the Level of Contamination. In: Sensor Signal Processing for Defence (SSPD), Edinburgh, UK, 9-10 Sept 2015, pp. 1-5. ISBN 9781479974443 (doi:10.1109/SSPD.2015.7288514)

This list was generated on Thu Nov 23 16:31:55 2017 GMT.