Dr Melanie Jimenez

  • Research Fellow (Biomedical Engineering)

Research interests

Research Interests

My research spans at the interface of engineering, physics and biology. My research interests include:

  • Microfluidics
  • Medical diagnostics
  • Sample processing (particle/cell separation)
  • Water engineering 
  • Antimicrobial resistance

For further information, please have a look at my Personal website

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Short Biosketch

  • Nov 2017: I started my EPSRC Research Fellowship on new approaches to separate pathogens from clinical samples for rapid medical diagnostics (Glasgow). 
  • Fev. 2016: I joined Jon Cooper's group on advanced, low-cost and reliable medical diagnostics using microsystems (Glasgow).
  • Jul. 2016: I received an EPSRC IAA as Co-Investigator to focus on microfluidic approaches to purify manufactured red blood cells from STEM cells (Heriot-Watt University). 
  • Feb. 2014: I joined the EU AQUAVALENS project as a PDRA to develop label-free microfluidic devices for isolating pathogens from drinking water (Heriot-Watt University). 
  • Oct. 2013: I received a Ph.D. degree in Process Engineering (Toulouse, France), working in collaboration with SUEZ on new optical methods for characterizing mass transfer and hydrodynamic behaviours during aeration of wastewaters.

Grants

 

Royal Academy of Engineering Research Fellowship (2018-2023)

Engineering new microsystems for rapid bacteria purification (£665k) 

 

University of Glasgow Leadership Fellow Fund (2017-2023)

 £150k

 

EPSRC Research Fellowship (2017-2020)

New microsystems to tackle anti-microbial resistance (£450k)

 

Royal Academy of Engineering Ingenious grant (2017-2018)

Co-production of new teaching tools to promote biomedical engineering in schools (£23k)

 

Communicating Immunology Grant from the British Society for Immunology (2016)

Promoting the work of engineers and immunologists for detecting malaria (£1k)

 

Collaborative Funding (PI), EPSRC Physics of Life Network (2015) 

Two-day workshop to promote new collaborations at the interface of biology and physical sciences with international leaders (£3k)

 

Heriot-Watt EPSRC Impact Acceleration Award (co-I) (2015)                            

Development of new microfluidic tools for purifying manufactured red blood cells from STEM cells (£15k)

 

Doctoral Fellowship (PI), French ministry of Higher Education (2010-2013)                    

Supporting top students to pursue with a Ph.D. thesis (£57k)

 

Grant (co-I), funded by international company SUEZ (2010-2013)

Consumables and travels to international conferences/collaborations (£47k)


Supervision

I am currently supervising the following Ph.D. students:

  • Andrew Farthing, University of Glasgow (2018-...) Engineering new biomarkers for pathogen detection to tackle antimicrobial resistance

I am mentoring/mentored the following Ph.D. students:

  • Ewa Guzniczack, Heriot-Watt University (2015-…) Microfluidics for STEM cell purification
  • Anusha Keloth, Heriot-Watt University (2015-2017) Optofluidics for rare marine cell isolation
  • Brian Miller, University of Edinburgh (2014-2015) Large scale microfluidics for high throughput particle separation

Additional information

Awards, distinctions

  • Selected for Scottish Crucible (2018)
  • University of Glasgow Engaged Researcher of the Year (2017)
  • Nomination for the Top 50 Women in Engineering under 35 (2017)
  • Invited to SET for BRITAIN 2016-Engineering
  • SULSA prize for the best video about the importance of light in research (IOP video competition) (2015)
  • Wellcome Trust "Frontiers Innovator" Award for "talented and ambitious junior researchers looking to perform original interdisciplinary research" (2015)
  • Top papers  "Innovation" session at international GLS12 conference (New-York, July 2015)
  • Heriot-Watt Public Engagement 2015 prize in the category “Team award” (2015)
  • Best microfluidic design award, RAEng Ingenious Scheme (2015)

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2010
Number of items: 20.

2018

Guzniczak, E., Jimenez, M. , Irwin, M., Otto, O., Willoughby, N. and Bridle, H. (2018) Impact of poloxamer 188 (Pluronic F-68) additive on cell mechanical properties, quantification by real-time deformability cytometry. Biomicrofluidics, 12(4), 044118. (doi:10.1063/1.5040316)

2017

Guzniczak, E., Mohammad Zadeh, M., Dempsey, F., Jimenez, M. , Bock, H., Whyte, G., Willoughby, N. and Bridle, H. (2017) High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing. Scientific Reports, 7, 14457. (doi:10.1038/s41598-017-14958-w) (PMID:29089557) (PMCID:PMC5663858)

Xu, F., Jimenez, M. , Dietrich, N. and Hébrard, G. (2017) Fast determination of gas-liquid diffusion coefficient by an innovative double approach. Chemical Engineering Science, 170, pp. 68-76. (doi:10.1016/j.ces.2017.02.043)

Jimenez, M. , Miller, B. and Bridle, H. L. (2017) Efficient separation of small microparticles at high flowrates using spiral channels: Application to waterborne pathogens. Chemical Engineering Science, 157, pp. 247-254. (doi:10.1016/j.ces.2015.08.042)

Keloth, A., Jimenez, M. , Kar, A. and Paterson, L. (2017) Particle Manipulation within an Ultrafast Laser Inscribed Optofluidic Device. In: Optical Trapping Applications 2017, San Diego, CA, USA, 2-5 April 2017, OtW2E.3. (doi:10.1364/OTA.2017.OtW2E.3)

Miller, B., Jimenez, M. and Bridle, H. (2017) Cascading and parallelising curvilinear inertial focusing systems for high volume, wide size distribution, separation and concentration of particles. Scientific Reports, 6(1), 36386. (doi:10.1038/srep36386) (PMID:27808244) (PMCID:PMC5093461)

2016

Jimenez, M. and Bridle, H. (2016) Microfluidics for effective concentration and sorting of waterborne protozoan pathogens. Journal of Microbiological Methods, 126, pp. 8-11. (doi:10.1016/j.mimet.2016.04.008) (PMID:27074367)

Gray, B. L., Becker, H., Keloth, A., Jimenez, M. , Bridle, H., Paterson, L., Markx, G. H. and Kar, A. K. (2016) Femtosecond Laser Fabricated Integrated Chip for Manipulation of Single Cells. SPIE BIOS 2016, San Francisco, CA, USA, 13-18 Feb 2016. 97050K. (doi:10.1117/12.2212719)

2015

McKenna, I., Tonolini, F., Tobin, R., Houssineau, J., Bridle, H., McDougall, C., Schlangen, I., McGrath, J. S., Jimenez, M. and Clark, D. E. (2015) Observing the Dynamics of Waterborne Pathogens for Assessing the Level of Contamination. In: Sensor Signal Processing for Defence (SSPD), Edinburgh, UK, 9-10 Sept 2015, pp. 1-5. ISBN 9781479974443 (doi:10.1109/SSPD.2015.7288514)

Dietrich, N., Francois, J., Jimenez, M. , Cockx, A., Guiraud, P. and Hébrard, G. (2015) Fast measurements of the gas-liquid diffusion coefficient in the Gaussian wake of a spherical bubble. Chemical Engineering and Technology, 38(5), pp. 941-946. (doi:10.1002/ceat.201400471)

Jimenez, M. and Bridle, H. L. (2015) Angry pathogens, how to get rid of them: introducing microfluidics for waterborne pathogen separation to children. Lab on a Chip, 15(4), pp. 947-957. (doi:10.1039/c4lc00944d) (PMID:25435144)

2014

Jimenez, M. , Dietrich, N., Grace, J. R. and Hébrard, G. (2014) Oxygen mass transfer and hydrodynamic behaviour in wastewater: Determination of local impact of surfactants by visualization techniques. Water Research, 58, pp. 111-121. (doi:10.1016/j.watres.2014.03.065) (PMID:24747142)

McGrath, J., Jimenez, M. and Bridle, H. (2014) Deterministic lateral displacement for particle separation: a review. Lab on a Chip, 14(21), pp. 4139-4158. (doi:10.1039/C4LC00939H)

2013

Dietrich, N., Loubière, K., Jimenez, M. , Hébrard, G. and Gourdon, C. (2013) A new direct technique for visualizing and measuring gas–liquid mass transfer around bubbles moving in a straight millimetric square channel. Chemical Engineering Science, 100, pp. 172-182. (doi:10.1016/j.ces.2013.03.041)

Jimenez, M. , Dietrich, N. and Hébrard, G. (2013) Mass transfer in the wake of non-spherical air bubbles quantified by quenching of fluorescence. Chemical Engineering Science, 100, pp. 160-171. (doi:10.1016/j.ces.2013.01.036)

Kherbeche, A., Milnes, J., Jimenez, M. , Dietrich, N., Hébrard, G. and Lekhlif, B. (2013) Multi-scale analysis of the influence of physicochemical parameters on the hydrodynamic and gas–liquid mass transfer in gas/liquid/solid reactors. Chemical Engineering Science, 100, pp. 515-528. (doi:10.1016/j.ces.2013.06.025)

Jimenez, M. , Dietrich, N., Cockx, A. and Hébrard, G. (2013) Experimental study of O2 diffusion coefficient measurement at a planar gas-liquid interface by planar laser-induced fluorescence with inhibition. AIChE Journal, 59(1), pp. 325-333. (doi:10.1002/aic.13805)

2012

Jimenez, M. , Dietrich, N. and Hebrard, G. (2012) A new method for measuring diffusion coefficient of gases in liquids by PLIF. Modern Physics Letters B, 26(06), 1150034. (doi:10.1142/S0217984911500345)

2010

de Gracia, A., Rincón, L., Castell, A., Jimenez, M. , Boer, D., Medrano, M. and Cabeza, L. F. (2010) Life cycle assessment of the inclusion of phase change materials (PCM) in experimental buildings. Energy and Buildings, 42(9), pp. 1517-1523. (doi:10.1016/j.enbuild.2010.03.022)

Gebreslassie, B., Jimenez, M. , Guillen-Gosalbez, G., Jimenez, L. and Boer, D. (2010) Multi-objective optimization of solar assisted absorption cooling system. In: Pierucci, S. (ed.) 20th European Symposium of Computer Aided Process Engineering. Series: Computer-aided chemical engineering (28). Elsevier: Amsterdam, pp. 1033-1038. ISBN 9780444535696

This list was generated on Fri Dec 14 20:46:41 2018 GMT.
Number of items: 20.

Articles

Guzniczak, E., Jimenez, M. , Irwin, M., Otto, O., Willoughby, N. and Bridle, H. (2018) Impact of poloxamer 188 (Pluronic F-68) additive on cell mechanical properties, quantification by real-time deformability cytometry. Biomicrofluidics, 12(4), 044118. (doi:10.1063/1.5040316)

Guzniczak, E., Mohammad Zadeh, M., Dempsey, F., Jimenez, M. , Bock, H., Whyte, G., Willoughby, N. and Bridle, H. (2017) High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing. Scientific Reports, 7, 14457. (doi:10.1038/s41598-017-14958-w) (PMID:29089557) (PMCID:PMC5663858)

Xu, F., Jimenez, M. , Dietrich, N. and Hébrard, G. (2017) Fast determination of gas-liquid diffusion coefficient by an innovative double approach. Chemical Engineering Science, 170, pp. 68-76. (doi:10.1016/j.ces.2017.02.043)

Jimenez, M. , Miller, B. and Bridle, H. L. (2017) Efficient separation of small microparticles at high flowrates using spiral channels: Application to waterborne pathogens. Chemical Engineering Science, 157, pp. 247-254. (doi:10.1016/j.ces.2015.08.042)

Miller, B., Jimenez, M. and Bridle, H. (2017) Cascading and parallelising curvilinear inertial focusing systems for high volume, wide size distribution, separation and concentration of particles. Scientific Reports, 6(1), 36386. (doi:10.1038/srep36386) (PMID:27808244) (PMCID:PMC5093461)

Jimenez, M. and Bridle, H. (2016) Microfluidics for effective concentration and sorting of waterborne protozoan pathogens. Journal of Microbiological Methods, 126, pp. 8-11. (doi:10.1016/j.mimet.2016.04.008) (PMID:27074367)

Dietrich, N., Francois, J., Jimenez, M. , Cockx, A., Guiraud, P. and Hébrard, G. (2015) Fast measurements of the gas-liquid diffusion coefficient in the Gaussian wake of a spherical bubble. Chemical Engineering and Technology, 38(5), pp. 941-946. (doi:10.1002/ceat.201400471)

Jimenez, M. and Bridle, H. L. (2015) Angry pathogens, how to get rid of them: introducing microfluidics for waterborne pathogen separation to children. Lab on a Chip, 15(4), pp. 947-957. (doi:10.1039/c4lc00944d) (PMID:25435144)

Jimenez, M. , Dietrich, N., Grace, J. R. and Hébrard, G. (2014) Oxygen mass transfer and hydrodynamic behaviour in wastewater: Determination of local impact of surfactants by visualization techniques. Water Research, 58, pp. 111-121. (doi:10.1016/j.watres.2014.03.065) (PMID:24747142)

McGrath, J., Jimenez, M. and Bridle, H. (2014) Deterministic lateral displacement for particle separation: a review. Lab on a Chip, 14(21), pp. 4139-4158. (doi:10.1039/C4LC00939H)

Dietrich, N., Loubière, K., Jimenez, M. , Hébrard, G. and Gourdon, C. (2013) A new direct technique for visualizing and measuring gas–liquid mass transfer around bubbles moving in a straight millimetric square channel. Chemical Engineering Science, 100, pp. 172-182. (doi:10.1016/j.ces.2013.03.041)

Jimenez, M. , Dietrich, N. and Hébrard, G. (2013) Mass transfer in the wake of non-spherical air bubbles quantified by quenching of fluorescence. Chemical Engineering Science, 100, pp. 160-171. (doi:10.1016/j.ces.2013.01.036)

Kherbeche, A., Milnes, J., Jimenez, M. , Dietrich, N., Hébrard, G. and Lekhlif, B. (2013) Multi-scale analysis of the influence of physicochemical parameters on the hydrodynamic and gas–liquid mass transfer in gas/liquid/solid reactors. Chemical Engineering Science, 100, pp. 515-528. (doi:10.1016/j.ces.2013.06.025)

Jimenez, M. , Dietrich, N., Cockx, A. and Hébrard, G. (2013) Experimental study of O2 diffusion coefficient measurement at a planar gas-liquid interface by planar laser-induced fluorescence with inhibition. AIChE Journal, 59(1), pp. 325-333. (doi:10.1002/aic.13805)

Jimenez, M. , Dietrich, N. and Hebrard, G. (2012) A new method for measuring diffusion coefficient of gases in liquids by PLIF. Modern Physics Letters B, 26(06), 1150034. (doi:10.1142/S0217984911500345)

de Gracia, A., Rincón, L., Castell, A., Jimenez, M. , Boer, D., Medrano, M. and Cabeza, L. F. (2010) Life cycle assessment of the inclusion of phase change materials (PCM) in experimental buildings. Energy and Buildings, 42(9), pp. 1517-1523. (doi:10.1016/j.enbuild.2010.03.022)

Book Sections

Gebreslassie, B., Jimenez, M. , Guillen-Gosalbez, G., Jimenez, L. and Boer, D. (2010) Multi-objective optimization of solar assisted absorption cooling system. In: Pierucci, S. (ed.) 20th European Symposium of Computer Aided Process Engineering. Series: Computer-aided chemical engineering (28). Elsevier: Amsterdam, pp. 1033-1038. ISBN 9780444535696

Conference or Workshop Item

Gray, B. L., Becker, H., Keloth, A., Jimenez, M. , Bridle, H., Paterson, L., Markx, G. H. and Kar, A. K. (2016) Femtosecond Laser Fabricated Integrated Chip for Manipulation of Single Cells. SPIE BIOS 2016, San Francisco, CA, USA, 13-18 Feb 2016. 97050K. (doi:10.1117/12.2212719)

Conference Proceedings

Keloth, A., Jimenez, M. , Kar, A. and Paterson, L. (2017) Particle Manipulation within an Ultrafast Laser Inscribed Optofluidic Device. In: Optical Trapping Applications 2017, San Diego, CA, USA, 2-5 April 2017, OtW2E.3. (doi:10.1364/OTA.2017.OtW2E.3)

McKenna, I., Tonolini, F., Tobin, R., Houssineau, J., Bridle, H., McDougall, C., Schlangen, I., McGrath, J. S., Jimenez, M. and Clark, D. E. (2015) Observing the Dynamics of Waterborne Pathogens for Assessing the Level of Contamination. In: Sensor Signal Processing for Defence (SSPD), Edinburgh, UK, 9-10 Sept 2015, pp. 1-5. ISBN 9781479974443 (doi:10.1109/SSPD.2015.7288514)

This list was generated on Fri Dec 14 20:46:41 2018 GMT.