BME research is featured on a cover of Angewandte Chemie
Issued: Wed, 22 Jan 2014 11:04:00 GMT
Prof Jon Cooper and colleagues from the Biomedical Engineering research division, along with collaborators from the School of Medical Veterinary and Life Sciences, have shown how the shape of a cell effects the field that it experiences within an optoelectronic device. Their paper "Shape Dependent Optoelectronic Cell Lysis" shows how the electric field lines bend around a cell close to a photoconductve surface so that the shape of the cell has an impact on how much voltage is across its membrane. This contrasts with previous studies where only the size of the cell has an appricable effect allowing for the first time the selective lysis of smaller but differently shaped cells. This is demonstrated with the lysis of red blood cells in the presence of both white blood cells and blood borne parasites showing the potential of this technique to enrich rare cell types in a blood sample. For more information please contact Prof Jon Cooper.