Professor Neil Isaacs

  • Honorary Research Fellow (School of Chemistry)

telephone: 01413305954
email: Neil.Isaacs@glasgow.ac.uk

Publications

List by: Type | Date

Jump to: 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 1996
Number of items: 50.

2012

McLuskey, K., Rudolf, J., Proto, W. R., Isaacs, N. W., Coombs, G. H., Moss, C. X. and Mottram, J. C. (2012) Crystal structure of a Trypanosoma brucei metacaspase. Proceedings of the National Academy of Sciences of the United States of America, 109(19), pp. 7469-7474. (doi:10.1073/pnas.1200885109)

2011

Hounsome, J. D.A., Baillie, S., Noofeli, M., Riboldi-Tunnicliffe, A., Burchmore, R. J.S. , Isaacs, N. W. and Davies, R. L. (2011) Outer membrane protein A of bovine and ovine isolates of mannheimia haemolytica is surface exposed and contains host species-specific epitopes. Infection and Immunity, 79(11), pp. 4332-4341. (doi:10.1128/IAI.05469-11)

Gabrielsen, M., Kroner, F., Black, I., Isaacs, N.W., Roe, A.J. and McLuskey, K. (2011) High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins. Molecular Membrane Biology, 28(7-8), pp. 445-453. (doi:10.3109/09687688.2011.628954)

Cogdell, R. J. , Gardiner, A. T., Roszak, A. W., Stončius, S., Kocovsky, P. and Isaacs, N. W. (2011) Mapping lipid and detergent molecules at the surface of membrane protein. Biochemical Society Transactions, 39(3), pp. 775-779. (doi:10.1042/BST0390775)

Zhai, Y. et al. (2011) Autotransporter passenger domain secretion requires a hydrophobic cavity at the extracellular entrance of the β-domain pore. Biochemical Journal, 435(3), pp. 577-587. (doi:10.1042/BJ20101548)

2010

McLuskey, K., Paterson, N. G., Bland, N. D., Isaacs, N. W. and Mottram, J. C. (2010) Crystal structure of leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. Journal of Biological Chemistry, 285(50), pp. 39249-39259. (doi:10.1074/jbc.M110.156679)

Gabrielsen, M., Zetterström, C.E., Wang, D., Beckham, K.S.H., Elofsson, M., Isaacs, N.W. and Roe, A. (2010) Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(12), pp. 1606-1609. (doi:10.1107/S1744309110039679)

Gabrielsen, M., Abdul-Rahman, P.S., Isaacs, N.W., Hashim, O.H. and Cogdell, R.J. (2010) Crystallization and initial X-ray diffraction analysis of a mannose-binding lectin from champedak. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(5), pp. 592-594. (doi:10.1107/S1744309110011760)

Horsham, M., Saxby, H., Blake, J., Isaacs, N., Mitchell, T.J. and Riboldi-Tunnicliffe, A. (2010) Expression, purification, crystallization and preliminary X-ray crystallographic data from TktA, a transketolase from the lactic acid bacteriumLactobacillus salivarius. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(8), pp. 899-901. (doi:10.1107/S1744309110012157)

McLuskey, K., Roszak, A. W., Zhu, Y. S. and Isaacs, N. W. (2010) Crystal structures of all-alpha type membrane proteins. European Biophysics Journal with Biophysics Letters, 39(5), pp. 723-755. (doi:10.1007/s00249-009-0546-6)

2009

Gabrielsen, M., Riboldi-Tunnicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W. and Cogdell, R.J. (2009) Crystallization and preliminary structural studies of champedak galactose-binding lectin. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 65(9), pp. 895-897. (doi:10.1107/S1744309109029303)

Nibbs, R. J.B. , McLean, P., McCulloch, C., Riboldi‐Tunnicliffe, A., Blair, E., Zhu, Y., Isaacs, N. and Graham, G. J. (2009) Structure–function dissection of D6, an atypical scavenger receptor. In: Abelson, J. N. and Simon, M. I. (eds.) Chemokines, Part A. Series: Methods in enzymology (460). Academic Press: Amsterdam, pp. 245-261. ISBN 9780123749086 (doi:10.1016/S0076-6879(09)05212-4)

2008

Cogdell, R.J. , Gardiner, A.T., Gabrielsen, M., Southall, J., Roszak, A.W., Isaacs, N.W., Fujii, R. and Hashimoto, H. (2008) The structure of purple bacterial antenna complexes. In: Frome, P. (ed.) Photosynthetic Protein Complexes: A Structural Approach. Wiley-VCH, pp. 325-339. ISBN 9783527317301

McCulloch, C., Morrow, V., Milasta, S., Comerford, I., Milligan, G. , Graham, G. , Isaacs, N. and Nibbs, R. (2008) Multiple roles for the C-terminal tail of the chemokine scavenger D6. Journal of Biological Chemistry, 283(12), pp. 7972-7982. (doi:10.1074/jbc.M710128200)

McLuskey, K., Gabrielsen, M., Kroner, F., Black, I., Cogdell, R.J. and Isaacs, N.W. (2008) A protocol for high throughput methods for the expression and purification of inner membrane proteins. Molecular Membrane Biology, 25(8), pp. 599-608. (doi:10.1080/09687680802510289)

Zhu, F., Kapitan, J., Tranter, G.E., Pudney, P.D.A., Isaacs, N.W., Hecht, L. and Barron, L.D. (2008) Residual structure in disordered peptides and unfolded proteins from multivariate analysis and ab initio simulation of Raman optical activity data. Proteins: Structure Function and Bioinformatics, 70(3), pp. 823-833. (doi:10.1002/prot.21593)

2007

Barron, L., Zhu, F., Hecht, L., Tranter, G. and Isaacs, N. (2007) Raman optical activity: An incisive probe of molecular chirality and biomolecular structure. Journal of Molecular Structure, 834, pp. 7-16. (doi:10.1016/j.molstruc.2006.10.033)

Barron, L. D., Zhu, F., Hecht, L. and Isaacs, N. W. (2007) Structure and behavior of proteins from Raman optical activity. In: Uversky, V. N. and Permyakov, E. A. (eds.) Methods in Protein Structure and Stability Analysis: Vibrational Spectroscopy. Series: Molecular anatomy and physiology of proteins. Nova Biomedical Books: New York, pp. 27-68. ISBN 9781600217036

Roszak, A.W., Gardiner, A.T., Isaacs, N.W. and Cogdell, R.J. (2007) Brominated lipids identify lipid binding sites on the surface of the reaction center from Rhodobacter sphaeroides. Biochemistry, 46(11), pp. 2909-2916. (doi:10.1021/bi062154i)

Zhu, Y.S., Black, I., Roszak, A.W. and Isaacs, N.W. (2007) Crystallization and preliminary X-ray diffraction analysis of P30, the transmembrane domain of pertactin, an autotransporter from Bordetella pertussis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 63(7), pp. 593-595. (doi:10.1107/S1744309107028308)

2006

Cogdell, R.J. , Southall, J., Gardiner, A.T., Law, C.J., Gall, A., Roszak, A.W. and Isaacs, N.W. (2006) How purple photosynthetic bacteria harvest solar energy. Comptes Rendus Chimie, 9(2), pp. 201-206. (doi:10.1016/j.crci.2005.03.035)

Hashimoto, H. et al. (2006) Structures and functions of carotenoids bound to reaction centers from purple photosynthetic bacteria. Pure and Applied Chemistry, 78(8), pp. 1505-1518. (doi:10.1351/pac200678081505)

Ottersbach, K., Mclean, J., Isaacs, N. and Graham, G. (2006) A 3(10) helical turn is essential for the proliferation-inhibiting properties of macrophage inflammatory protein-1 alpha (CCL3). Blood, 107, pp. 1284-1291. (doi:10.1182/blood-2005-08-3112)

Paterson, N., Riboldi-Tunicliffe, A., Mitchell, T. and Isaacs, N. (2006) Overexpression, purification and crystallization of a choline-binding protein CbpI from Streptococcus pneumoniae. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 62, pp. 672-675. (doi:10.1107/S1744309106020616)

Paterson, N., Riboldi-Tunnicliffe, A., Mitchell, T. and Isaacs, N. (2006) Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 62, pp. 676-679. (doi:10.1107/S1744309106021695)

Zhu, F., Isaacs, N., Hecht, L., Tranter, G. and Barron, L. (2006) Raman optical activity of proteins, carbohydrates and glycoproteins. Chirality, 18, pp. 103-115. (doi:10.1002/chir.20225)

Zhu, F., Tranter, G., Isaacs, N., Hecht, L. and Barron, L. (2006) Delineation of protein structure classes from multivariate analysis of protein Raman optical activity data. Journal of Molecular Biology, 363, pp. 19-26. (doi:10.1016/j.jmb.2006.08.038)

2005

Riboldi-Tunnicliffe, A., Isaacs, N.W. and Mitchell, T.J. (2005) 1.2 Å crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold. FEBS Letters, 579(24), pp. 5353-5360. (doi:10.1016/j.febslet.2005.08.066)

Cao, Z.B., Roszak, A.W., Gourlay, L.J., Lindsay, J.G. and Isaacs, N.W. (2005) Bovine mitochondrial peroxiredoxin III forms a two-ring catenane. Structure, 13(11), pp. 1661-1664. (doi:10.1016/i.str.2005.07.021)

Law, C.J., Gardiner, A.T., Southall, J., Roszak, A.W., Howard, T.D., Isaacs, N.W. and Cogdell, R.J. (2005) How purple bacteria harvest light energy. In: Andrews, D.L. (ed.) Energy Harvesting Materials. World Scientific Publishing. ISBN 9789812564122

Zhu, F., Isaacs, N., Hecht, L. and Barron, L. (2005) Polypeptide and carbohydrate structure of an intact glycoprotein from Raman optical activity. Journal of the American Chemical Society, 127, pp. 6142-6143.

Zhu, F., Isaacs, N., Hecht, L. and Barron, L. (2005) Raman optical activity: A tool for protein structure analysis. Structure, 13, pp. 1409-1419. (doi:10.1016/j.str.2005.07.009)

2004

Bent, C., Isaacs, N., Mitchell, T. and Riboldi-Tunnicliffe, A. (2004) Crystal structure of the response regulator 02 receiver domain, the essential YycF two-component system of Streptococcus pneumoniae in both complexed and native states. Journal of Bacteriology, 186, pp. 2872-2879. (doi:10.1128/JB.186.9.2872-2879.2004)

Blackburn, P., Simpson, C., Nibbs, R., OHara, M., Booth, R., Poulos, J., Isaacs, N. and Graham, G. (2004) Purification and biochemical characterization of the D6 chemokine receptor. Biochemical Journal, 379, pp. 263-272.

Cogdell, R.J., Gardiner, A.T., Roszak, A.W., Law, C.J., Southall, J. and Isaacs, N.W. (2004) Rings, ellipses and horseshoes: how purple bacteria harvest solar energy. Photosynthesis Research, 81(3), pp. 207-214. (doi:10.1023/B:PRES.0000036883.56959.a9)

Law, C.J., Roszak, A.W., Southall, J., Gardiner, A.T., Isaacs, N.W. and Cogdell, R.J. (2004) The structure and function of bacterial light-harvesting complexes (Review). Molecular Membrane Biology, 21(3), pp. 183-191. (doi:10.1080/09687680410001697224)

Riboldi-Tunnicliffe, A., Bent, C., Isaacs, N. and Mitchell, T. (2004) Expression, purification and X-ray characterization of residues 18-230 from the pneumococcal histidine triad protein A (PhtA) from Streptococcus pneumoniae. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 926-928. (doi:10.1107/S0907444904004573)

Riboldi-Tunnicliffe, A., Trombe, M., Bent, C., Isaacs, N. and Mitchell, T. (2004) Crystallization and preliminary crystallographic studies of the D59A mutant of MicA, a YycF response-regulator homologue from Streptococcus pneumoniae. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 950-951. (doi:10.1107/S0907444904005712)

Roszak, A.W., McKendrick, K., Gardiner, A.T., Mitchell, I.A., Isaacs, N.W., Cogdell, R.J., Hashimoto, H. and Frank, H.A. (2004) Protein regulation of carotenoid binding: Gatekeeper and locking amino acid residues in reaction centers of Rhodobacter sphaeroides. Structure, 12, pp. 765-773. (doi:10.1016/j.str.2004.02.037)

2003

Roszak, A.W., Howard, T.D., Southall, J., Gardiner, A.T., Law, C.J., Isaacs, N.W. and Cogdell, R.J. (2003) Crystal structure of the RC-LH1 core complex from Rhodopseudomonas palustris. Science, 302(5652), pp. 1969-1972. (doi:10.1126/science.1088892)

Bent, C., Isaacs, N., Mitchell, T. and Riboldi-Tunnicliffe, A. (2003) Cloning, overexpression, purification, crystallization and preliminary diffraction analysis of the receiver domain of MicA. Acta Crystallographica. Section D: Biological Crystallography, 59, pp. 758-760. (doi:10.1107/S090744490300372X)

Riboldi-Tunnicliffe, A., Bent, C., Isaacs, N. and Mitchell, T. (2003) Purification, crystallization and preliminary X-ray analysis of the Enterococcus faecalis protein EF0377. Acta Crystallographica. Section D: Biological Crystallography, 59, pp. 755-757. (doi:10.1107/S0907444903003718)

2002

Jones, M.R., Fyfe, P.K., Roszak, A.W., Isaacs, N.W. and Cogdell, R.J. (2002) Protein-lipid interactions in the purple bacterial reaction centre. Biochimica et Biophysica Acta: Biomembranes, 1565(2), pp. 206-214. (doi:10.1016/S0005-2736(02)00570-9)

Juarez-Martinez, G., Steinmann, P., Roszak, A.W., Isaacs, N.W. and Cooper, J.M. (2002) High-throughput screens for postgenomics: Studies of protein crystallization using microsystems technology. Analytical Chemistry, 74(14), pp. 3505-3510. (doi:10.1021/ac0112519)

Spiedel, D. et al. (2002) Tuning of the optical and electrochemical properties of the primary donor bacteriochlorophylls in the reaction centre from Rhodobacter sphaeroides: spectroscopy and structure. Biochimica et Biophysica Acta: Bioenergetics, 1554(1-2), pp. 75-93. (doi:10.1016/S0005-2728(02)00215-3)

2001

Fotinou, C., Emsley, P., Black, I., Ando, H., Ishida, H., Kiso, M., Sinha, K., Fairweather, N. and Isaacs, N. (2001) The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. Journal of Biological Chemistry, 276, pp. 32274-32281.

Fyfe, P.K., McAuley, K.E., Roszak, A.W., Isaacs, N.W., Cogdell, R.J. and Jones, M.R. (2001) Probing the interface between membrane proteins and membrane lipids by X-ray crystallography. Trends in Biochemical Sciences, 26(2), pp. 106-112. (doi:10.1016/S0968-0004(00)01746-1)

Song, Y., Ji, I., Beauchamp, J., Isaacs, N. and Ji, T. (2001) Hormone interactions to Leu-rich repeats in the gonadotropin receptors - I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor. Journal of Biological Chemistry, 276, pp. 3426-3435.

Song, Y., Ji, I., Beauchamp, J., Isaacs, N. and Ji, T. (2001) Hormone interactions to Leu-rich repeats in the gonadotropin receptors - II. Analysis of Leu-rich repeat 4 of human luteinizing hormone/chorionic gonadotropin receptor. Journal of Biological Chemistry, 276, pp. 3436-3442.

1996

Emsley, P., Charles, I.G., Fairweather, N.F. and Isaacs, N.W. (1996) Structure of Bordetella pertussis virulence factor P.69 pertactin. Nature, 381(6577), pp. 90-92. (doi:10.1038/427016a)

This list was generated on Mon Jul 15 23:08:53 2019 BST.
Number of items: 50.

Articles

McLuskey, K., Rudolf, J., Proto, W. R., Isaacs, N. W., Coombs, G. H., Moss, C. X. and Mottram, J. C. (2012) Crystal structure of a Trypanosoma brucei metacaspase. Proceedings of the National Academy of Sciences of the United States of America, 109(19), pp. 7469-7474. (doi:10.1073/pnas.1200885109)

Hounsome, J. D.A., Baillie, S., Noofeli, M., Riboldi-Tunnicliffe, A., Burchmore, R. J.S. , Isaacs, N. W. and Davies, R. L. (2011) Outer membrane protein A of bovine and ovine isolates of mannheimia haemolytica is surface exposed and contains host species-specific epitopes. Infection and Immunity, 79(11), pp. 4332-4341. (doi:10.1128/IAI.05469-11)

Gabrielsen, M., Kroner, F., Black, I., Isaacs, N.W., Roe, A.J. and McLuskey, K. (2011) High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins. Molecular Membrane Biology, 28(7-8), pp. 445-453. (doi:10.3109/09687688.2011.628954)

Cogdell, R. J. , Gardiner, A. T., Roszak, A. W., Stončius, S., Kocovsky, P. and Isaacs, N. W. (2011) Mapping lipid and detergent molecules at the surface of membrane protein. Biochemical Society Transactions, 39(3), pp. 775-779. (doi:10.1042/BST0390775)

Zhai, Y. et al. (2011) Autotransporter passenger domain secretion requires a hydrophobic cavity at the extracellular entrance of the β-domain pore. Biochemical Journal, 435(3), pp. 577-587. (doi:10.1042/BJ20101548)

McLuskey, K., Paterson, N. G., Bland, N. D., Isaacs, N. W. and Mottram, J. C. (2010) Crystal structure of leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. Journal of Biological Chemistry, 285(50), pp. 39249-39259. (doi:10.1074/jbc.M110.156679)

Gabrielsen, M., Zetterström, C.E., Wang, D., Beckham, K.S.H., Elofsson, M., Isaacs, N.W. and Roe, A. (2010) Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(12), pp. 1606-1609. (doi:10.1107/S1744309110039679)

Gabrielsen, M., Abdul-Rahman, P.S., Isaacs, N.W., Hashim, O.H. and Cogdell, R.J. (2010) Crystallization and initial X-ray diffraction analysis of a mannose-binding lectin from champedak. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(5), pp. 592-594. (doi:10.1107/S1744309110011760)

Horsham, M., Saxby, H., Blake, J., Isaacs, N., Mitchell, T.J. and Riboldi-Tunnicliffe, A. (2010) Expression, purification, crystallization and preliminary X-ray crystallographic data from TktA, a transketolase from the lactic acid bacteriumLactobacillus salivarius. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 66(8), pp. 899-901. (doi:10.1107/S1744309110012157)

McLuskey, K., Roszak, A. W., Zhu, Y. S. and Isaacs, N. W. (2010) Crystal structures of all-alpha type membrane proteins. European Biophysics Journal with Biophysics Letters, 39(5), pp. 723-755. (doi:10.1007/s00249-009-0546-6)

Gabrielsen, M., Riboldi-Tunnicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W. and Cogdell, R.J. (2009) Crystallization and preliminary structural studies of champedak galactose-binding lectin. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 65(9), pp. 895-897. (doi:10.1107/S1744309109029303)

McCulloch, C., Morrow, V., Milasta, S., Comerford, I., Milligan, G. , Graham, G. , Isaacs, N. and Nibbs, R. (2008) Multiple roles for the C-terminal tail of the chemokine scavenger D6. Journal of Biological Chemistry, 283(12), pp. 7972-7982. (doi:10.1074/jbc.M710128200)

McLuskey, K., Gabrielsen, M., Kroner, F., Black, I., Cogdell, R.J. and Isaacs, N.W. (2008) A protocol for high throughput methods for the expression and purification of inner membrane proteins. Molecular Membrane Biology, 25(8), pp. 599-608. (doi:10.1080/09687680802510289)

Zhu, F., Kapitan, J., Tranter, G.E., Pudney, P.D.A., Isaacs, N.W., Hecht, L. and Barron, L.D. (2008) Residual structure in disordered peptides and unfolded proteins from multivariate analysis and ab initio simulation of Raman optical activity data. Proteins: Structure Function and Bioinformatics, 70(3), pp. 823-833. (doi:10.1002/prot.21593)

Barron, L., Zhu, F., Hecht, L., Tranter, G. and Isaacs, N. (2007) Raman optical activity: An incisive probe of molecular chirality and biomolecular structure. Journal of Molecular Structure, 834, pp. 7-16. (doi:10.1016/j.molstruc.2006.10.033)

Roszak, A.W., Gardiner, A.T., Isaacs, N.W. and Cogdell, R.J. (2007) Brominated lipids identify lipid binding sites on the surface of the reaction center from Rhodobacter sphaeroides. Biochemistry, 46(11), pp. 2909-2916. (doi:10.1021/bi062154i)

Zhu, Y.S., Black, I., Roszak, A.W. and Isaacs, N.W. (2007) Crystallization and preliminary X-ray diffraction analysis of P30, the transmembrane domain of pertactin, an autotransporter from Bordetella pertussis. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 63(7), pp. 593-595. (doi:10.1107/S1744309107028308)

Cogdell, R.J. , Southall, J., Gardiner, A.T., Law, C.J., Gall, A., Roszak, A.W. and Isaacs, N.W. (2006) How purple photosynthetic bacteria harvest solar energy. Comptes Rendus Chimie, 9(2), pp. 201-206. (doi:10.1016/j.crci.2005.03.035)

Hashimoto, H. et al. (2006) Structures and functions of carotenoids bound to reaction centers from purple photosynthetic bacteria. Pure and Applied Chemistry, 78(8), pp. 1505-1518. (doi:10.1351/pac200678081505)

Ottersbach, K., Mclean, J., Isaacs, N. and Graham, G. (2006) A 3(10) helical turn is essential for the proliferation-inhibiting properties of macrophage inflammatory protein-1 alpha (CCL3). Blood, 107, pp. 1284-1291. (doi:10.1182/blood-2005-08-3112)

Paterson, N., Riboldi-Tunicliffe, A., Mitchell, T. and Isaacs, N. (2006) Overexpression, purification and crystallization of a choline-binding protein CbpI from Streptococcus pneumoniae. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 62, pp. 672-675. (doi:10.1107/S1744309106020616)

Paterson, N., Riboldi-Tunnicliffe, A., Mitchell, T. and Isaacs, N. (2006) Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 62, pp. 676-679. (doi:10.1107/S1744309106021695)

Zhu, F., Isaacs, N., Hecht, L., Tranter, G. and Barron, L. (2006) Raman optical activity of proteins, carbohydrates and glycoproteins. Chirality, 18, pp. 103-115. (doi:10.1002/chir.20225)

Zhu, F., Tranter, G., Isaacs, N., Hecht, L. and Barron, L. (2006) Delineation of protein structure classes from multivariate analysis of protein Raman optical activity data. Journal of Molecular Biology, 363, pp. 19-26. (doi:10.1016/j.jmb.2006.08.038)

Riboldi-Tunnicliffe, A., Isaacs, N.W. and Mitchell, T.J. (2005) 1.2 Å crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold. FEBS Letters, 579(24), pp. 5353-5360. (doi:10.1016/j.febslet.2005.08.066)

Cao, Z.B., Roszak, A.W., Gourlay, L.J., Lindsay, J.G. and Isaacs, N.W. (2005) Bovine mitochondrial peroxiredoxin III forms a two-ring catenane. Structure, 13(11), pp. 1661-1664. (doi:10.1016/i.str.2005.07.021)

Zhu, F., Isaacs, N., Hecht, L. and Barron, L. (2005) Polypeptide and carbohydrate structure of an intact glycoprotein from Raman optical activity. Journal of the American Chemical Society, 127, pp. 6142-6143.

Zhu, F., Isaacs, N., Hecht, L. and Barron, L. (2005) Raman optical activity: A tool for protein structure analysis. Structure, 13, pp. 1409-1419. (doi:10.1016/j.str.2005.07.009)

Bent, C., Isaacs, N., Mitchell, T. and Riboldi-Tunnicliffe, A. (2004) Crystal structure of the response regulator 02 receiver domain, the essential YycF two-component system of Streptococcus pneumoniae in both complexed and native states. Journal of Bacteriology, 186, pp. 2872-2879. (doi:10.1128/JB.186.9.2872-2879.2004)

Blackburn, P., Simpson, C., Nibbs, R., OHara, M., Booth, R., Poulos, J., Isaacs, N. and Graham, G. (2004) Purification and biochemical characterization of the D6 chemokine receptor. Biochemical Journal, 379, pp. 263-272.

Cogdell, R.J., Gardiner, A.T., Roszak, A.W., Law, C.J., Southall, J. and Isaacs, N.W. (2004) Rings, ellipses and horseshoes: how purple bacteria harvest solar energy. Photosynthesis Research, 81(3), pp. 207-214. (doi:10.1023/B:PRES.0000036883.56959.a9)

Law, C.J., Roszak, A.W., Southall, J., Gardiner, A.T., Isaacs, N.W. and Cogdell, R.J. (2004) The structure and function of bacterial light-harvesting complexes (Review). Molecular Membrane Biology, 21(3), pp. 183-191. (doi:10.1080/09687680410001697224)

Riboldi-Tunnicliffe, A., Bent, C., Isaacs, N. and Mitchell, T. (2004) Expression, purification and X-ray characterization of residues 18-230 from the pneumococcal histidine triad protein A (PhtA) from Streptococcus pneumoniae. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 926-928. (doi:10.1107/S0907444904004573)

Riboldi-Tunnicliffe, A., Trombe, M., Bent, C., Isaacs, N. and Mitchell, T. (2004) Crystallization and preliminary crystallographic studies of the D59A mutant of MicA, a YycF response-regulator homologue from Streptococcus pneumoniae. Acta Crystallographica. Section D: Biological Crystallography, 60, pp. 950-951. (doi:10.1107/S0907444904005712)

Roszak, A.W., McKendrick, K., Gardiner, A.T., Mitchell, I.A., Isaacs, N.W., Cogdell, R.J., Hashimoto, H. and Frank, H.A. (2004) Protein regulation of carotenoid binding: Gatekeeper and locking amino acid residues in reaction centers of Rhodobacter sphaeroides. Structure, 12, pp. 765-773. (doi:10.1016/j.str.2004.02.037)

Roszak, A.W., Howard, T.D., Southall, J., Gardiner, A.T., Law, C.J., Isaacs, N.W. and Cogdell, R.J. (2003) Crystal structure of the RC-LH1 core complex from Rhodopseudomonas palustris. Science, 302(5652), pp. 1969-1972. (doi:10.1126/science.1088892)

Bent, C., Isaacs, N., Mitchell, T. and Riboldi-Tunnicliffe, A. (2003) Cloning, overexpression, purification, crystallization and preliminary diffraction analysis of the receiver domain of MicA. Acta Crystallographica. Section D: Biological Crystallography, 59, pp. 758-760. (doi:10.1107/S090744490300372X)

Riboldi-Tunnicliffe, A., Bent, C., Isaacs, N. and Mitchell, T. (2003) Purification, crystallization and preliminary X-ray analysis of the Enterococcus faecalis protein EF0377. Acta Crystallographica. Section D: Biological Crystallography, 59, pp. 755-757. (doi:10.1107/S0907444903003718)

Jones, M.R., Fyfe, P.K., Roszak, A.W., Isaacs, N.W. and Cogdell, R.J. (2002) Protein-lipid interactions in the purple bacterial reaction centre. Biochimica et Biophysica Acta: Biomembranes, 1565(2), pp. 206-214. (doi:10.1016/S0005-2736(02)00570-9)

Juarez-Martinez, G., Steinmann, P., Roszak, A.W., Isaacs, N.W. and Cooper, J.M. (2002) High-throughput screens for postgenomics: Studies of protein crystallization using microsystems technology. Analytical Chemistry, 74(14), pp. 3505-3510. (doi:10.1021/ac0112519)

Spiedel, D. et al. (2002) Tuning of the optical and electrochemical properties of the primary donor bacteriochlorophylls in the reaction centre from Rhodobacter sphaeroides: spectroscopy and structure. Biochimica et Biophysica Acta: Bioenergetics, 1554(1-2), pp. 75-93. (doi:10.1016/S0005-2728(02)00215-3)

Fotinou, C., Emsley, P., Black, I., Ando, H., Ishida, H., Kiso, M., Sinha, K., Fairweather, N. and Isaacs, N. (2001) The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. Journal of Biological Chemistry, 276, pp. 32274-32281.

Fyfe, P.K., McAuley, K.E., Roszak, A.W., Isaacs, N.W., Cogdell, R.J. and Jones, M.R. (2001) Probing the interface between membrane proteins and membrane lipids by X-ray crystallography. Trends in Biochemical Sciences, 26(2), pp. 106-112. (doi:10.1016/S0968-0004(00)01746-1)

Song, Y., Ji, I., Beauchamp, J., Isaacs, N. and Ji, T. (2001) Hormone interactions to Leu-rich repeats in the gonadotropin receptors - I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor. Journal of Biological Chemistry, 276, pp. 3426-3435.

Song, Y., Ji, I., Beauchamp, J., Isaacs, N. and Ji, T. (2001) Hormone interactions to Leu-rich repeats in the gonadotropin receptors - II. Analysis of Leu-rich repeat 4 of human luteinizing hormone/chorionic gonadotropin receptor. Journal of Biological Chemistry, 276, pp. 3436-3442.

Emsley, P., Charles, I.G., Fairweather, N.F. and Isaacs, N.W. (1996) Structure of Bordetella pertussis virulence factor P.69 pertactin. Nature, 381(6577), pp. 90-92. (doi:10.1038/427016a)

Book Sections

Nibbs, R. J.B. , McLean, P., McCulloch, C., Riboldi‐Tunnicliffe, A., Blair, E., Zhu, Y., Isaacs, N. and Graham, G. J. (2009) Structure–function dissection of D6, an atypical scavenger receptor. In: Abelson, J. N. and Simon, M. I. (eds.) Chemokines, Part A. Series: Methods in enzymology (460). Academic Press: Amsterdam, pp. 245-261. ISBN 9780123749086 (doi:10.1016/S0076-6879(09)05212-4)

Cogdell, R.J. , Gardiner, A.T., Gabrielsen, M., Southall, J., Roszak, A.W., Isaacs, N.W., Fujii, R. and Hashimoto, H. (2008) The structure of purple bacterial antenna complexes. In: Frome, P. (ed.) Photosynthetic Protein Complexes: A Structural Approach. Wiley-VCH, pp. 325-339. ISBN 9783527317301

Barron, L. D., Zhu, F., Hecht, L. and Isaacs, N. W. (2007) Structure and behavior of proteins from Raman optical activity. In: Uversky, V. N. and Permyakov, E. A. (eds.) Methods in Protein Structure and Stability Analysis: Vibrational Spectroscopy. Series: Molecular anatomy and physiology of proteins. Nova Biomedical Books: New York, pp. 27-68. ISBN 9781600217036

Law, C.J., Gardiner, A.T., Southall, J., Roszak, A.W., Howard, T.D., Isaacs, N.W. and Cogdell, R.J. (2005) How purple bacteria harvest light energy. In: Andrews, D.L. (ed.) Energy Harvesting Materials. World Scientific Publishing. ISBN 9789812564122

This list was generated on Mon Jul 15 23:08:53 2019 BST.