Dr Amanda MacKenzie

  • Affiliate (School of Chemistry)

email: Amanda.Mackenzie@glasgow.ac.uk

Keltic Pharma Therapeutics

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011
Number of items: 11.

2021

Lin, L.-C., Quon, T., Engberg, S., Mackenzie, A. E., Tobin, A. B. and Milligan, G. (2021) G protein-coupled receptor GPR35 suppresses lipid accumulation in hepatocytes. ACS Pharmacology and Translational Science, 4(6), pp. 1835-1848. (doi: 10.1021/acsptsci.1c00224) (PMID:34927014)

Boleij, A. et al. (2021) G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis. Communications Biology, 4, 585. (doi: 10.1038/s42003-021-02014-3) (PMID:33990686) (PMCID:PMC8121840)

2020

Marti-Solano, M. et al. (2020) Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature, 587, pp. 650-656. (doi: 10.1038/s41586-020-2888-2) (PMID:33149304)

2019

Mackenzie, A. E., Quon, T., Lin, L.-C., Hauser, A. S., Jenkins, L. , Inoue, A., Tobin, A. B. , Gloriam, D. E., Hudson, B. D. and Milligan, G. (2019) Receptor selectivity between the G proteins Gα12 and Gα13 is defined by a single leucine-to-isoleucine variation. FASEB Journal, 33(4), pp. 5005-5017. (doi: 10.1096/fj.201801956R) (PMID:30601679) (PMCID:PMC6436656)

2018

Binti Mohd Amir, N. A.S., Mackenzie, A. E., Jenkins, L. , Boustani, K., Hillier, M. C., Tsuchiya, T., Milligan, G. and Pease, J. E. (2018) Evidence for the existence of a CXCL17 receptor distinct from GPR35. Journal of Immunology, 201(2), pp. 714-724. (doi: 10.4049/jimmunol.1700884) (PMID:29875152) (PMCID:PMC6036231)

2017

Mackenzie, A. E. and Milligan, G. (2017) The emerging pharmacology and function of GPR35 in the nervous system. Neuropharmacology, 113(part B), pp. 661-671. (doi: 10.1016/j.neuropharm.2015.07.035) (PMID:26232640)

2016

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C. , Milligan, G. and Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52(6), pp. 383-395. (doi: 10.1159/000444754) (PMID:27064272) (PMCID:PMC4959467)

2015

Divorty, N., Mackenzie, A., Nicklin, S. and Milligan, G. (2015) G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease. Frontiers in Pharmacology, 6, 41. (doi: 10.3389/fphar.2015.00041) (PMID:25805994) (PMCID:PMC4354270)

2014

Mackenzie, A.E. et al. (2014) The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat gpr35. Molecular Pharmacology, 85(1), pp. 91-104. (doi: 10.1124/mol.113.089482)

2013

Mackenzie, A. E., Neetoo-Isseljee, Z., Southern, C., Jerman, J., McIver, E. G., Hudson, B. D. , Taylor, D. L. and Milligan, G. (2013) Novel and potent GPR35 agonists aid identification of residues important in ligand interaction. FASEB Journal, 27, 655.1.

2011

Mackenzie, A.E., Lappin, J.E., Taylor, D.L., Nicklin, S.A. and Milligan, G. (2011) GPR35 as a novel therapeutic target. Frontiers in Endocrinology, 2, 68. (doi: 10.3389/fendo.2011.00068) (PMID:22654822) (PMCID:PMC3356001)

This list was generated on Mon Jun 27 19:12:58 2022 BST.
Jump to: Articles
Number of items: 11.

Articles

Lin, L.-C., Quon, T., Engberg, S., Mackenzie, A. E., Tobin, A. B. and Milligan, G. (2021) G protein-coupled receptor GPR35 suppresses lipid accumulation in hepatocytes. ACS Pharmacology and Translational Science, 4(6), pp. 1835-1848. (doi: 10.1021/acsptsci.1c00224) (PMID:34927014)

Boleij, A. et al. (2021) G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis. Communications Biology, 4, 585. (doi: 10.1038/s42003-021-02014-3) (PMID:33990686) (PMCID:PMC8121840)

Marti-Solano, M. et al. (2020) Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature, 587, pp. 650-656. (doi: 10.1038/s41586-020-2888-2) (PMID:33149304)

Mackenzie, A. E., Quon, T., Lin, L.-C., Hauser, A. S., Jenkins, L. , Inoue, A., Tobin, A. B. , Gloriam, D. E., Hudson, B. D. and Milligan, G. (2019) Receptor selectivity between the G proteins Gα12 and Gα13 is defined by a single leucine-to-isoleucine variation. FASEB Journal, 33(4), pp. 5005-5017. (doi: 10.1096/fj.201801956R) (PMID:30601679) (PMCID:PMC6436656)

Binti Mohd Amir, N. A.S., Mackenzie, A. E., Jenkins, L. , Boustani, K., Hillier, M. C., Tsuchiya, T., Milligan, G. and Pease, J. E. (2018) Evidence for the existence of a CXCL17 receptor distinct from GPR35. Journal of Immunology, 201(2), pp. 714-724. (doi: 10.4049/jimmunol.1700884) (PMID:29875152) (PMCID:PMC6036231)

Mackenzie, A. E. and Milligan, G. (2017) The emerging pharmacology and function of GPR35 in the nervous system. Neuropharmacology, 113(part B), pp. 661-671. (doi: 10.1016/j.neuropharm.2015.07.035) (PMID:26232640)

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C. , Milligan, G. and Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52(6), pp. 383-395. (doi: 10.1159/000444754) (PMID:27064272) (PMCID:PMC4959467)

Divorty, N., Mackenzie, A., Nicklin, S. and Milligan, G. (2015) G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease. Frontiers in Pharmacology, 6, 41. (doi: 10.3389/fphar.2015.00041) (PMID:25805994) (PMCID:PMC4354270)

Mackenzie, A.E. et al. (2014) The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat gpr35. Molecular Pharmacology, 85(1), pp. 91-104. (doi: 10.1124/mol.113.089482)

Mackenzie, A. E., Neetoo-Isseljee, Z., Southern, C., Jerman, J., McIver, E. G., Hudson, B. D. , Taylor, D. L. and Milligan, G. (2013) Novel and potent GPR35 agonists aid identification of residues important in ligand interaction. FASEB Journal, 27, 655.1.

Mackenzie, A.E., Lappin, J.E., Taylor, D.L., Nicklin, S.A. and Milligan, G. (2011) GPR35 as a novel therapeutic target. Frontiers in Endocrinology, 2, 68. (doi: 10.3389/fendo.2011.00068) (PMID:22654822) (PMCID:PMC3356001)

This list was generated on Mon Jun 27 19:12:58 2022 BST.