SCMH Dr fuller collaborates with KCL in new study

A new study from King's College London, funded by the British Heart Foundation, provides new insights into the mechanisms of heart failure and identifies potential novel therapeutic targets.  

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Heart failure is a global pandemic affecting more than 64 million people worldwide.  It is a debilitating disease with a greater than 50% mortality within 5 years and few effective treatments. 

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A new study from King's College London, funded by the British Heart Foundation, provides new insights into the mechanisms of heart failure and identifies potential novel therapeutic targets. 

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In this study, lead by Professor Mike Shattock at King's College London, researchers from London, Glasgow (Dr Will Fuller), Dundee, Birmingham and Texas have collaborated to show that irrespective of whether this elevation of sodium is induced acutely by drugs, or more long-term by heart failure or a genetic mutation, these all share a common 'metabolic fingerprint' shifting the energy supply away from fatty acids towards the use of other energy sources. 

Link to full article: https://www.nature.com/articles/s41467-020-18160-x

First published: 4 September 2020