Dr Katharine Herbert
- Affiliate (School of Cancer Sciences)
email:
Katharine.Herbert@glasgow.ac.uk
Wolfson Wohl Cancer Research Centre, College of Medical, Veterinary and Life Sciences, University of Glasgow, Gascube Estate, Switchback Road
Publications
2021
Herbert, K. J. , Puliyadi, R., Prevo, R., Rodriguez-Berriguete, G., Ryan, A., Ramadan, K. and Higgins, G. S. (2021) Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress. Cell Death and Differentiation, 28(4), pp. 1333-1346. (doi: 10.1038/s41418-020-00655-1) (PMID:33168956) (PMCID:PMC8027845)
2020
Pokrovska, T. D. et al. (2020) External beam radiation therapy and enadenotucirev: inhibition of the DDR and mechanisms of radiation-mediated virus increase. Cancers, 12(4), e798. (doi: 10.3390/cancers12040798) (PMID:32224979) (PMCID:PMC7226394)
2018
Herbert, K. J. , Ashton, T. M., Prevo, R., Pirovano, G. and Higgins, G. S. (2018) T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics. Cell Death and Disease, 9, 1089. (doi: 10.1038/s41419-018-1131-7) (PMID:30356039) (PMCID:PMC6200809)
Prevo, R., Pirovano, G., Puliyadi, R., Herbert, K. J. , Rodriguez-Berriguete, G., O’Docherty, A., Greaves, W., McKenna, W. G. and Higgins, G. S. (2018) CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner. Cell Cycle, 17(12), pp. 1513-1523. (doi: 10.1080/15384101.2018.1491236) (PMID:30045664) (PMCID:PMC6132956)
2017
Pirovano, G. et al. (2017) TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy. British Journal of Cancer, 117(4), pp. 503-512. (doi: 10.1038/bjc.2017.197) (PMID:28677687) (PMCID:PMC5558685)
2014
Herbert, K. J. , Holloway, A., Cook, A. J., Chin, S. P. and Snow, E. T. (2014) Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes. Toxicology and Applied Pharmacology, 281(1), pp. 136-145. (doi: 10.1016/j.taap.2014.09.012) (PMID:25281835)
Herbert, K. J. , Cook, A. L. and Snow, E. T. (2014) SIRT1 inhibition restores apoptotic sensitivity in p53-mutated human keratinocytes. Toxicology and Applied Pharmacology, 277(3), pp. 288-297. (doi: 10.1016/j.taap.2014.04.001) (PMID:24726431)
Herbert, K. J. , Cook, A. L. and Snow, E. T. (2014) SIRT1 modulates miRNA processing defects in p53-mutated human keratinocytes. Journal of Dermatological Science, 74(2), pp. 142-149. (doi: 10.1016/j.jdermsci.2014.01.008) (PMID:24548601)
2012
Herbert, K. J. and Snow, E. T. (2012) Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol. Chemico-Biological Interactions, 198(1-3), pp. 38-48. (doi: 10.1016/j.cbi.2012.05.004) (PMID:22634503)
Articles
Herbert, K. J. , Puliyadi, R., Prevo, R., Rodriguez-Berriguete, G., Ryan, A., Ramadan, K. and Higgins, G. S. (2021) Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress. Cell Death and Differentiation, 28(4), pp. 1333-1346. (doi: 10.1038/s41418-020-00655-1) (PMID:33168956) (PMCID:PMC8027845)
Pokrovska, T. D. et al. (2020) External beam radiation therapy and enadenotucirev: inhibition of the DDR and mechanisms of radiation-mediated virus increase. Cancers, 12(4), e798. (doi: 10.3390/cancers12040798) (PMID:32224979) (PMCID:PMC7226394)
Herbert, K. J. , Ashton, T. M., Prevo, R., Pirovano, G. and Higgins, G. S. (2018) T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics. Cell Death and Disease, 9, 1089. (doi: 10.1038/s41419-018-1131-7) (PMID:30356039) (PMCID:PMC6200809)
Prevo, R., Pirovano, G., Puliyadi, R., Herbert, K. J. , Rodriguez-Berriguete, G., O’Docherty, A., Greaves, W., McKenna, W. G. and Higgins, G. S. (2018) CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner. Cell Cycle, 17(12), pp. 1513-1523. (doi: 10.1080/15384101.2018.1491236) (PMID:30045664) (PMCID:PMC6132956)
Pirovano, G. et al. (2017) TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy. British Journal of Cancer, 117(4), pp. 503-512. (doi: 10.1038/bjc.2017.197) (PMID:28677687) (PMCID:PMC5558685)
Herbert, K. J. , Holloway, A., Cook, A. J., Chin, S. P. and Snow, E. T. (2014) Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes. Toxicology and Applied Pharmacology, 281(1), pp. 136-145. (doi: 10.1016/j.taap.2014.09.012) (PMID:25281835)
Herbert, K. J. , Cook, A. L. and Snow, E. T. (2014) SIRT1 inhibition restores apoptotic sensitivity in p53-mutated human keratinocytes. Toxicology and Applied Pharmacology, 277(3), pp. 288-297. (doi: 10.1016/j.taap.2014.04.001) (PMID:24726431)
Herbert, K. J. , Cook, A. L. and Snow, E. T. (2014) SIRT1 modulates miRNA processing defects in p53-mutated human keratinocytes. Journal of Dermatological Science, 74(2), pp. 142-149. (doi: 10.1016/j.jdermsci.2014.01.008) (PMID:24548601)
Herbert, K. J. and Snow, E. T. (2012) Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol. Chemico-Biological Interactions, 198(1-3), pp. 38-48. (doi: 10.1016/j.cbi.2012.05.004) (PMID:22634503)