Dr Ania Wilczynska
- Honorary Lecturer (School of Cancer Sciences)
Publications
2023
Whyte, D. et al. (2023) NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology, (doi: 10.1002/1878-0261.13425) (PMID:36975767) (Early Online Publication)
Schmidt, T. et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), pp. 1859-1879. (doi: 10.1093/nar/gkad030) (PMID:36727461) (PMCID:PMC9976904)
2022
Pantaleão, L. C. et al. (2022) Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner. eLife, 11, e69078. (doi: 10.7554/elife.69078) (PMID:35025731) (PMCID:PMC8794468)
2021
Gillen, S. L., Giacomelli, C., Hodge, K., Zanivan, S. , Bushell, M. and Wilczynska, A. (2021) Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization. Genome Biology, 22, 284. (doi: 10.1186/s13059-021-02494-w) (PMID:34615539) (PMCID:PMC8496106)
Heydt, Q. et al. (2021) Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence. Nature Communications, 12, 5507. (doi: 10.1038/s41467-021-25540-4) (PMID:34535653) (PMCID:PMC8448863)
Kiourtis, C. , Wilczynska, A., Nixon, C., Clark, W., May, S. and Bird, T. G. (2021) Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biology Open, 10(9), bio058678. (doi: 10.1242/bio.058678) (PMID:34435198) (PMCID:PMC8487635)
2019
Waldron, J. A., Tack, D. C., Ritchey, L. E., Gillen, S. L., Wilczynska, A., Turro, E., Bevilacqua, P. C., Assmann, S. M., Bushell, M. and Le Quesne, J. (2019) mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity. Genome Biology, 20(1), 300. (doi: 10.1186/s13059-019-1901-2) (PMID:31888698) (PMCID:PMC6936103)
Wilczynska, A. et al. (2019) eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5’UTR. Genome Biology, 20, 262. (doi: 10.1186/s13059-019-1857-2) (PMID:31791371) (PMCID:PMC6886185)
Articles
Whyte, D. et al. (2023) NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology, (doi: 10.1002/1878-0261.13425) (PMID:36975767) (Early Online Publication)
Schmidt, T. et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), pp. 1859-1879. (doi: 10.1093/nar/gkad030) (PMID:36727461) (PMCID:PMC9976904)
Pantaleão, L. C. et al. (2022) Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner. eLife, 11, e69078. (doi: 10.7554/elife.69078) (PMID:35025731) (PMCID:PMC8794468)
Gillen, S. L., Giacomelli, C., Hodge, K., Zanivan, S. , Bushell, M. and Wilczynska, A. (2021) Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization. Genome Biology, 22, 284. (doi: 10.1186/s13059-021-02494-w) (PMID:34615539) (PMCID:PMC8496106)
Heydt, Q. et al. (2021) Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence. Nature Communications, 12, 5507. (doi: 10.1038/s41467-021-25540-4) (PMID:34535653) (PMCID:PMC8448863)
Kiourtis, C. , Wilczynska, A., Nixon, C., Clark, W., May, S. and Bird, T. G. (2021) Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice. Biology Open, 10(9), bio058678. (doi: 10.1242/bio.058678) (PMID:34435198) (PMCID:PMC8487635)
Waldron, J. A., Tack, D. C., Ritchey, L. E., Gillen, S. L., Wilczynska, A., Turro, E., Bevilacqua, P. C., Assmann, S. M., Bushell, M. and Le Quesne, J. (2019) mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity. Genome Biology, 20(1), 300. (doi: 10.1186/s13059-019-1901-2) (PMID:31888698) (PMCID:PMC6936103)
Wilczynska, A. et al. (2019) eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5’UTR. Genome Biology, 20, 262. (doi: 10.1186/s13059-019-1857-2) (PMID:31791371) (PMCID:PMC6886185)