Dr George Skalka

  • Research Assistant (Therapeutic Science Research)

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021 | 2019 | 2018 | 2015
Number of items: 9.

2023

May, S. et al. (2023) Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration. Journal of Hepatology, 78(5), pp. 1028-1036. (doi: 10.1016/j.jhep.2023.01.009) (PMID:36702176)

Whyte, D. et al. (2023) NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology, (doi: 10.1002/1878-0261.13425) (PMID:36975767) (Early Online Publication)

2022

Bader, A. S., Luessing, J., Hawley, B. R., Skalka, G. L., Lu, W.-T., Lowndes, N. F. and Bushell, M. (2022) DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci. Nucleic Acids Research, 50(18), pp. 10487-10502. (doi: 10.1093/nar/gkac843) (PMID:36200807) (PMCID:PMC9561282)

2021

Knight, J. R.P. et al. (2021) MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. Cancer Discovery, 11(5), pp. 1228-1247. (doi: 10.1158/2159-8290.CD-20-0652) (PMID:33328217)

2019

Skalka, G., Hall, H., Somers, J., Bushell, M. , Willis, A. and Malewicz, M. (2019) Leucine zipper and ICAT domain containing (LZIC) protein regulates cell cycle transitions in response to ionizing radiation. Cell Cycle, 18(9), pp. 963-975. (doi: 10.1080/15384101.2019.1601476) (PMID:30973299) (PMCID:PMC6527300)

Munnur, D., Somers, J., Skalka, G., Weston, R., Jukes-Jones, R., Bhogadia, M., Dominguez, C., Cain, K., Ahel, I. and Malewicz, M. (2019) NR4A nuclear receptors target poly-ADP-ribosylated DNA-PKcs protein to promote DNA repair. Cell Reports, 26(8), 2028-2036.e6. (doi: 10.1016/j.celrep.2019.01.083) (PMID:30784586) (PMCID:PMC6381605)

2018

Craxton, A., Munnur, D., Jukes-Jones, R., Skalka, G., Langlais, C., Cain, K. and Malewicz, M. (2018) PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair. Nature Communications, 9, 3877. (doi: 10.1038/s41467-018-06127-y) (PMID:30250067) (PMCID:PMC6155126)

Lu, W.-T., Hawley, B. R., Skalka, G. L., Baldock, R. A., Smith, E. M., Bader, A. S., Malewicz, M., Watts, F. Z., Wilczynska, A. and Bushell, M. (2018) Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair. Nature Communications, 9, 532. (doi: 10.1038/s41467-018-02893-x) (PMID:29416038) (PMCID:PMC5803274)

2015

Hollingworth, R., Skalka, G. L., Stewart, G. S., Hislop, A. D., Blackbourn, D. J. and Grand, R. J. (2015) Activation of DNA damage response pathways during lytic replication of KSHV. Viruses, 7(6), pp. 2908-2927. (doi: 10.3390/v7062752) (PMID:26057167) (PMCID:PMC4488719)

This list was generated on Thu Jun 8 19:31:03 2023 BST.
Jump to: Articles
Number of items: 9.

Articles

May, S. et al. (2023) Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration. Journal of Hepatology, 78(5), pp. 1028-1036. (doi: 10.1016/j.jhep.2023.01.009) (PMID:36702176)

Whyte, D. et al. (2023) NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. Molecular Oncology, (doi: 10.1002/1878-0261.13425) (PMID:36975767) (Early Online Publication)

Bader, A. S., Luessing, J., Hawley, B. R., Skalka, G. L., Lu, W.-T., Lowndes, N. F. and Bushell, M. (2022) DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci. Nucleic Acids Research, 50(18), pp. 10487-10502. (doi: 10.1093/nar/gkac843) (PMID:36200807) (PMCID:PMC9561282)

Knight, J. R.P. et al. (2021) MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression. Cancer Discovery, 11(5), pp. 1228-1247. (doi: 10.1158/2159-8290.CD-20-0652) (PMID:33328217)

Skalka, G., Hall, H., Somers, J., Bushell, M. , Willis, A. and Malewicz, M. (2019) Leucine zipper and ICAT domain containing (LZIC) protein regulates cell cycle transitions in response to ionizing radiation. Cell Cycle, 18(9), pp. 963-975. (doi: 10.1080/15384101.2019.1601476) (PMID:30973299) (PMCID:PMC6527300)

Munnur, D., Somers, J., Skalka, G., Weston, R., Jukes-Jones, R., Bhogadia, M., Dominguez, C., Cain, K., Ahel, I. and Malewicz, M. (2019) NR4A nuclear receptors target poly-ADP-ribosylated DNA-PKcs protein to promote DNA repair. Cell Reports, 26(8), 2028-2036.e6. (doi: 10.1016/j.celrep.2019.01.083) (PMID:30784586) (PMCID:PMC6381605)

Craxton, A., Munnur, D., Jukes-Jones, R., Skalka, G., Langlais, C., Cain, K. and Malewicz, M. (2018) PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair. Nature Communications, 9, 3877. (doi: 10.1038/s41467-018-06127-y) (PMID:30250067) (PMCID:PMC6155126)

Lu, W.-T., Hawley, B. R., Skalka, G. L., Baldock, R. A., Smith, E. M., Bader, A. S., Malewicz, M., Watts, F. Z., Wilczynska, A. and Bushell, M. (2018) Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair. Nature Communications, 9, 532. (doi: 10.1038/s41467-018-02893-x) (PMID:29416038) (PMCID:PMC5803274)

Hollingworth, R., Skalka, G. L., Stewart, G. S., Hislop, A. D., Blackbourn, D. J. and Grand, R. J. (2015) Activation of DNA damage response pathways during lytic replication of KSHV. Viruses, 7(6), pp. 2908-2927. (doi: 10.3390/v7062752) (PMID:26057167) (PMCID:PMC4488719)

This list was generated on Thu Jun 8 19:31:03 2023 BST.