2019

Garza-Manero, S. et al. (2019) Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model. Epigenetics and Chromatin, 12, 73. (doi: 10.1186/s13072-019-0320-7) (PMID:31831052) (PMCID:PMC6907237)

2016

Garza-Manero, S., Sindi, A., Bailo, M., Mohan, G., Rehbini, O., Jeantet, V., West, A. and West, K. (2016) Nucleosome-binding HMGN Proteins Inhibit Stem Cell Differentiation Down the Neuronal Lineage. 2016 IMB Conference: Epigenetics in Development, Mainz, Germany, 20-22 Oct 2016.

2014

West, K. , Gourlay, E. and West, A. (2014) Genome Editing in Human Cells. Tenovus Scotland Scholarship Event, Glasgow, UK, 25 Jul 2014.

2013

Zhou, Y., Kurukuti, S., Saffrey, P., Vukovic, M., Michie, A.M. , Strogantsev, R., West, A.G. and Vetrie, D. (2013) Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL. Blood, 122(26), pp. 4199-4209. (doi: 10.1182/blood-2013-02-483875)

Baxter, E.W. et al. (2013) The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers. Journal of Immunology, 189(9), pp. 4459-4469. (doi: 10.4049/jimmunol.1201915)

2012

Barkess, G. and West, A. G. (2012) Chromatin insulator elements: establishing barriers to set heterochromatin boundaries. Epigenomics, 4(1), pp. 67-80. (doi: 10.2217/epi.11.112) (PMID:22332659)

Hassan-Zadeh, V., Chilaka, S., Cadoret, J.-C., Ma, M., Boggetto, N., West, A. G. and Prioleau, M.-N. (2012) USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator. PLoS Biology, 10(3), e1001277. (doi: 10.1371/journal.pbio.1001277) (PMID:22412349) (PMCID:PMC3295818)

Jiwaji, M. et al. (2012) Unique reporter-based sensor platforms to monitor signalling in cells. PLoS ONE, 7(11), e50521. (doi: 10.1371/journal.pone.0050521)

2011

Ma, M.K.-W., Heath, C., Hair, A. and West, A. (2011) Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. PLoS Genetics, 7(7), e1002175. (doi: 10.1371/journal.pgen.1002175) (PMID:21811414) (PMCID:PMC3140996)

2010

Dickson, J., Gowher, H., Strogantsev, R., Gaszner, M., Hair, A., Felsenfeld, G. and West, A. G. (2010) VEZF1 elements mediate protection from DNA methylation. PLoS Genetics, 6(1), e1000804. (doi: 10.1371/journal.pgen.1000804)

2007

Gaszner, M., Huang, S., West, A. and Felsenfeld, G. (2007) Epigenetic regulation at the chicken β-globin locus. Blood Cells, Molecules, and Diseases, 38(2), pp. 137-138. (doi: 10.1016/j.bcmd.2006.10.044)

2006

West, A.G. and van Attikum, H. (2006) Chromatin at the crossroads - meeting on signalling to chromatin epigenetics. EMBO Reports, 7(12), pp. 1206-1210. (doi: 10.1038/sj.embor.7400834)

2005

Yoon, B. et al. (2005) Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Molecular and Cellular Biology, 25(24), pp. 11184-11190. (doi: 10.1128/MCB.25.24.11184-11190.2005)

West, A.G. and Fraser, P. (2005) Remote control of gene transcription. Human Molecular Genetics, 14(Sup. 1), R101-R111. (doi: 10.1093/hmg/ddi104)

2004

West, A.G. , Huang, S., Gaszner, M., Litt, M.D. and Felsenfeld, G. (2004) Recruitment of histione modifications by USF proteins at a vertebrate barrier element. Molecular Cell, 16(3), pp. 453-463. (doi: 10.1016/j.molcel.2004.10.005)

Engel, N., West, A.G. , Felsenfeld, G. and Bartolomei, M.S. (2004) Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations. Nature Genetics, 36(8), pp. 883-888. (doi: 10.1038/ng1399)

Felsenfeld, G. et al. (2004) Chromatin boundaries and chromatin domains. Cold Spring Harbor Symposia on Quantitative Biology, 69(1), pp. 245-250. (doi: 10.1101/sqb.2004.69.245)

2003

Yao, S., Osborne, C.S., Bharadwaj, R.R., Pasceri, P., Sukonnik, T., Pannell, D., Recillas-Targa, F., West, A.G. and Ellis, J. (2003) Retrovirus silencer blocking by the cHS4 insulator is CTCF independent. Nucleic Acids Research, 31(18), pp. 5317-5323. (doi: 10.1093/nar/gkg742)

Lim, F.L., Hayes, A., West, A. , Pic-Taylor, A., Darieva, Z., Morgan, B.A., Oliver, S.G. and Sharrocks, A.D. (2003) Mcm1p-induced DNA bending regulates the formation of ternary transcription factor complexes. Molecular and Cellular Biology, 23(2), pp. 450-461. (doi: 10.1128/MCB.23.2.450-461.2003)

2002

Burgess-Beusse, B., Farrell, C., Gaszner, M., Litt, M., Mutskov, V., Recillas-Targa, F., Simpson, M., West, A.G. and Felsenfeld, G. (2002) The insulation of genes from external enhancers and silencing chromatin. Proceedings of the National Academy of Sciences of the United States of America, 99(Sup. 4), pp. 16433-16437. (doi: 10.1073/pnas.162342499)

Farrell, C.M., West, A.G. and Felsenfeld, G. (2002) Conserved CTCF insulator elements flank the mouse and human beta-globin loci. Molecular and Cellular Biology, 22(11), pp. 3820-3831. (doi: 10.1128/MCB.22.11.3820-3831.2002)

Recillas-Targa, F., Pikaart, M.J., Burgess-Beusse, B., Bell, A.C., Litt, M.D., West, A.G. , Gaszner, M. and Felsenfeld, G. (2002) Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities. Proceedings of the National Academy of Sciences of the United States of America, 99(10), pp. 6883-6888. (doi: 10.1073/pnas.102179399)

West, A.G. , Gaszner, M. and Felsenfeld, G. (2002) Insulators: many functions, many mechanisms. Genes and Development, 16(3), pp. 271-288. (doi: 10.1101/gad.954702)

2001

Bell, A.C., West, A.G. and Felsenfeld, G. (2001) Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. Science, 291(5503), pp. 447-450. (doi: 10.1126/science.291.5503.447)

2000

Saitoh, N., Bell, A.C., Recillas-Targa, F., West, A.G. , Simpson, M., Pikaart, M. and Felsenfeld, G. (2000) Structural and functional conservation at the boundaries of the chicken β-globin domain. EMBO Journal, 19(10), pp. 2315-2322. (doi: 10.1093/emboj/19.10.2315)

Pic, A., Lim, F.-L., Ross, S.J., Veal, E.A., Johnson, A.L., Sultan, M.R.A., West, A.G. , Johnson, L.H., Sharrocks, A.D. and Morgan, B.A. (2000) The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF. EMBO Journal, 19(14), pp. 3750-3761. (doi: 10.1093/emboj/19.14.3750)

1999

Bell, A.C., West, A.G. and Felsenfeld, G. (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell, 98(3), pp. 387-396. (doi: 10.1016/S0092-8674(00)81967-4)

West, A.G. and Sharrocks, A.D. (1999) MADS-box transcription factors adopt alternative mechanisms for bending DNA. Journal of Molecular Biology, 286(5), pp. 1311-1323. (doi: 10.1006/jmbi.1999.2576)

1998

Bell, A.C., Pikaart, M.J., Prioleau, M.N., Récillas-Targa, F., Saitoh, N., West, A.G. and Felsenfeld, G. (1998) Insulators and boundaries in the chicken β-globin locus. Blood Cells, Molecules, and Diseases, 24(4), pp. 464-465. (doi: 10.1006/bcmd.1998.0215)

Ling, Y., West, A.G. , Roberts, E.C., Lakey, J.H. and Sharrocks, A.D. (1998) Interaction of transcription factors with serum response factor: identification of the Elk-1 binding surface. Journal of Biological Chemistry, 273(17), pp. 10506-10514. (doi: 10.1074/jbc.273.17.10506)

West, A.G. , Causier, B.E., Davies, B. and Sharrocks, A.D. (1998) DNA binding and dimerisation determinants of Antirrhinum majus MADS-box transcription factors. Nucleic Acids Research, 26(23), pp. 5277-5287. (doi: 10.1093/nar/26.23.5277)

1997

West, A.G. and Sharrocks, A.D. (1997) The role of DNA-bending in MADS-box transcription factor function. Biochemical Society Transactions, 25(4), S639.

West, A.G. , Shore, P. and Sharrocks, A.D. (1997) DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Molecular and Cellular Biology, 17(5), pp. 2876-2887.

Articles

Garza-Manero, S. et al. (2019) Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model. Epigenetics and Chromatin, 12, 73. (doi: 10.1186/s13072-019-0320-7) (PMID:31831052) (PMCID:PMC6907237)

Zhou, Y., Kurukuti, S., Saffrey, P., Vukovic, M., Michie, A.M. , Strogantsev, R., West, A.G. and Vetrie, D. (2013) Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL. Blood, 122(26), pp. 4199-4209. (doi: 10.1182/blood-2013-02-483875)

Baxter, E.W. et al. (2013) The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers. Journal of Immunology, 189(9), pp. 4459-4469. (doi: 10.4049/jimmunol.1201915)

Barkess, G. and West, A. G. (2012) Chromatin insulator elements: establishing barriers to set heterochromatin boundaries. Epigenomics, 4(1), pp. 67-80. (doi: 10.2217/epi.11.112) (PMID:22332659)

Hassan-Zadeh, V., Chilaka, S., Cadoret, J.-C., Ma, M., Boggetto, N., West, A. G. and Prioleau, M.-N. (2012) USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator. PLoS Biology, 10(3), e1001277. (doi: 10.1371/journal.pbio.1001277) (PMID:22412349) (PMCID:PMC3295818)

Jiwaji, M. et al. (2012) Unique reporter-based sensor platforms to monitor signalling in cells. PLoS ONE, 7(11), e50521. (doi: 10.1371/journal.pone.0050521)

Ma, M.K.-W., Heath, C., Hair, A. and West, A. (2011) Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. PLoS Genetics, 7(7), e1002175. (doi: 10.1371/journal.pgen.1002175) (PMID:21811414) (PMCID:PMC3140996)

Dickson, J., Gowher, H., Strogantsev, R., Gaszner, M., Hair, A., Felsenfeld, G. and West, A. G. (2010) VEZF1 elements mediate protection from DNA methylation. PLoS Genetics, 6(1), e1000804. (doi: 10.1371/journal.pgen.1000804)

Gaszner, M., Huang, S., West, A. and Felsenfeld, G. (2007) Epigenetic regulation at the chicken β-globin locus. Blood Cells, Molecules, and Diseases, 38(2), pp. 137-138. (doi: 10.1016/j.bcmd.2006.10.044)

West, A.G. and van Attikum, H. (2006) Chromatin at the crossroads - meeting on signalling to chromatin epigenetics. EMBO Reports, 7(12), pp. 1206-1210. (doi: 10.1038/sj.embor.7400834)

Yoon, B. et al. (2005) Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Molecular and Cellular Biology, 25(24), pp. 11184-11190. (doi: 10.1128/MCB.25.24.11184-11190.2005)

West, A.G. and Fraser, P. (2005) Remote control of gene transcription. Human Molecular Genetics, 14(Sup. 1), R101-R111. (doi: 10.1093/hmg/ddi104)

West, A.G. , Huang, S., Gaszner, M., Litt, M.D. and Felsenfeld, G. (2004) Recruitment of histione modifications by USF proteins at a vertebrate barrier element. Molecular Cell, 16(3), pp. 453-463. (doi: 10.1016/j.molcel.2004.10.005)

Engel, N., West, A.G. , Felsenfeld, G. and Bartolomei, M.S. (2004) Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations. Nature Genetics, 36(8), pp. 883-888. (doi: 10.1038/ng1399)

Felsenfeld, G. et al. (2004) Chromatin boundaries and chromatin domains. Cold Spring Harbor Symposia on Quantitative Biology, 69(1), pp. 245-250. (doi: 10.1101/sqb.2004.69.245)

Yao, S., Osborne, C.S., Bharadwaj, R.R., Pasceri, P., Sukonnik, T., Pannell, D., Recillas-Targa, F., West, A.G. and Ellis, J. (2003) Retrovirus silencer blocking by the cHS4 insulator is CTCF independent. Nucleic Acids Research, 31(18), pp. 5317-5323. (doi: 10.1093/nar/gkg742)

Lim, F.L., Hayes, A., West, A. , Pic-Taylor, A., Darieva, Z., Morgan, B.A., Oliver, S.G. and Sharrocks, A.D. (2003) Mcm1p-induced DNA bending regulates the formation of ternary transcription factor complexes. Molecular and Cellular Biology, 23(2), pp. 450-461. (doi: 10.1128/MCB.23.2.450-461.2003)

Burgess-Beusse, B., Farrell, C., Gaszner, M., Litt, M., Mutskov, V., Recillas-Targa, F., Simpson, M., West, A.G. and Felsenfeld, G. (2002) The insulation of genes from external enhancers and silencing chromatin. Proceedings of the National Academy of Sciences of the United States of America, 99(Sup. 4), pp. 16433-16437. (doi: 10.1073/pnas.162342499)

Farrell, C.M., West, A.G. and Felsenfeld, G. (2002) Conserved CTCF insulator elements flank the mouse and human beta-globin loci. Molecular and Cellular Biology, 22(11), pp. 3820-3831. (doi: 10.1128/MCB.22.11.3820-3831.2002)

Recillas-Targa, F., Pikaart, M.J., Burgess-Beusse, B., Bell, A.C., Litt, M.D., West, A.G. , Gaszner, M. and Felsenfeld, G. (2002) Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities. Proceedings of the National Academy of Sciences of the United States of America, 99(10), pp. 6883-6888. (doi: 10.1073/pnas.102179399)

West, A.G. , Gaszner, M. and Felsenfeld, G. (2002) Insulators: many functions, many mechanisms. Genes and Development, 16(3), pp. 271-288. (doi: 10.1101/gad.954702)

Bell, A.C., West, A.G. and Felsenfeld, G. (2001) Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. Science, 291(5503), pp. 447-450. (doi: 10.1126/science.291.5503.447)

Saitoh, N., Bell, A.C., Recillas-Targa, F., West, A.G. , Simpson, M., Pikaart, M. and Felsenfeld, G. (2000) Structural and functional conservation at the boundaries of the chicken β-globin domain. EMBO Journal, 19(10), pp. 2315-2322. (doi: 10.1093/emboj/19.10.2315)

Pic, A., Lim, F.-L., Ross, S.J., Veal, E.A., Johnson, A.L., Sultan, M.R.A., West, A.G. , Johnson, L.H., Sharrocks, A.D. and Morgan, B.A. (2000) The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF. EMBO Journal, 19(14), pp. 3750-3761. (doi: 10.1093/emboj/19.14.3750)

Bell, A.C., West, A.G. and Felsenfeld, G. (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell, 98(3), pp. 387-396. (doi: 10.1016/S0092-8674(00)81967-4)

West, A.G. and Sharrocks, A.D. (1999) MADS-box transcription factors adopt alternative mechanisms for bending DNA. Journal of Molecular Biology, 286(5), pp. 1311-1323. (doi: 10.1006/jmbi.1999.2576)

Bell, A.C., Pikaart, M.J., Prioleau, M.N., Récillas-Targa, F., Saitoh, N., West, A.G. and Felsenfeld, G. (1998) Insulators and boundaries in the chicken β-globin locus. Blood Cells, Molecules, and Diseases, 24(4), pp. 464-465. (doi: 10.1006/bcmd.1998.0215)

Ling, Y., West, A.G. , Roberts, E.C., Lakey, J.H. and Sharrocks, A.D. (1998) Interaction of transcription factors with serum response factor: identification of the Elk-1 binding surface. Journal of Biological Chemistry, 273(17), pp. 10506-10514. (doi: 10.1074/jbc.273.17.10506)

West, A.G. , Causier, B.E., Davies, B. and Sharrocks, A.D. (1998) DNA binding and dimerisation determinants of Antirrhinum majus MADS-box transcription factors. Nucleic Acids Research, 26(23), pp. 5277-5287. (doi: 10.1093/nar/26.23.5277)

West, A.G. and Sharrocks, A.D. (1997) The role of DNA-bending in MADS-box transcription factor function. Biochemical Society Transactions, 25(4), S639.

West, A.G. , Shore, P. and Sharrocks, A.D. (1997) DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Molecular and Cellular Biology, 17(5), pp. 2876-2887.

Conference or Workshop Item

Garza-Manero, S., Sindi, A., Bailo, M., Mohan, G., Rehbini, O., Jeantet, V., West, A. and West, K. (2016) Nucleosome-binding HMGN Proteins Inhibit Stem Cell Differentiation Down the Neuronal Lineage. 2016 IMB Conference: Epigenetics in Development, Mainz, Germany, 20-22 Oct 2016.

West, K. , Gourlay, E. and West, A. (2014) Genome Editing in Human Cells. Tenovus Scotland Scholarship Event, Glasgow, UK, 25 Jul 2014.