Number of items: 22.
2020
Crowe, J. et al.
(2020)
The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.
PLoS Pathogens, 16(3),
e1008391.
(doi: 10.1371/journal.ppat.1008391)
(PMID:32163524)
(PMCID:PMC7108737)
2019
Doonan, J., Tarafdar, A., Pineda, M. A. , Lumb, F. E., Crowe, J., Khan, A. M., Hoskisson, P. A., Harnett, M. M. and Harnett, W.
(2019)
The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis.
Nature Communications, 10,
1554.
(doi: 10.1038/s41467-019-09361-0)
(PMID:30952846)
(PMCID:PMC6451002)
2018
Li, K. et al.
(2018)
Apigenin C-glycosides of Microcos paniculata protects lipopolysaccharide induced apoptosis and inflammation in acute lung injury through TLR4 signaling pathway.
Free Radical Biology and Medicine, 124,
pp. 163-175.
(doi: 10.1016/j.freeradbiomed.2018.06.009)
(PMID:29890216)
Doonan, J., Lumb, F. E., Pineda, M. A. , Tarafdar, A., Crowe, J., Khan, A. M., Suckling, C. J., Harnett, M. M. and Harnett, W.
(2018)
Protection against arthritis by the parasitic worm product ES-62, and its drug-like small molecule analogues, is associated with inhibition of osteoclastogenesis.
Frontiers in Immunology, 9,
1016.
(doi: 10.3389/fimmu.2018.01016)
(PMID:29867986)
(PMCID:PMC5967578)
2017
Lumb, F. E., Doonan, J., Bell, K. S., Pineda, M. A. , Corbet, M., Suckling, C. J., Harnett, M. M. and Harnett, W.
(2017)
Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62.
Scientific Reports, 7(1),
1704.
(doi: 10.1038/s41598-017-01651-1)
(PMID:28490801)
(PMCID:PMC5431997)
Harnett, M. M. , Pineda, M. A. , Latré de Laté, P., Eason, R. J., Besteiro, S., Harnett, W. and Langsley, G.
(2017)
From Christian de Duve to Yoshinori Ohsumi: more to autophagy than just dining at home.
Biomedical Journal, 40(1),
pp. 9-22.
(doi: 10.1016/j.bj.2016.12.004)
(PMID:28411887)
Laté de Laté, P., Pineda, M. , Harnett, M. , Harnett, W., Besteiro, S. and Langsley, G.
(2017)
Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells.
Biomedical Journal, 40(1),
pp. 23-30.
(doi: 10.1016/j.bj.2017.01.001)
(PMID:28411879)
2016
Eason, R. J., Bell, K. S., Marshall, F. A., Rodgers, D. T., Pineda, M. , Steiger, C. N., Al-Riyami, L., Harnett, W. and Harnett, M. M.
(2016)
The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosmal degradation of TLR-transducers, as exemplified by PKCδ.
Scientific Reports, 6,
37276.
(doi: 10.1038/srep37276)
(PMID:27869138)
(PMCID:PMC5116678)
2015
Al-Riyami, L., Rodgers, D. T., Rzepecka, J., Pineda, M. A. , Suckling, C. J., Harnett, M. M. and Harnett, W.
(2015)
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation.
Experimental Parasitology, 158,
pp. 18-22.
(doi: 10.1016/j.exppara.2015.03.025)
(PMID:25836375)
(PMCID:PMC4659540)
Rodgers, D. T., Pineda, M. A. , Suckling, C. J., Harnett, W. and Harnett, M. M.
(2015)
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus.
Lupus, 24(13),
pp. 1437-1442.
(doi: 10.1177/0961203315591031)
(PMID:26085597)
(PMCID:PMC4616909)
Pineda, M. A. , Cuervo, H., Fresno, M., Soto, M. and Bonay, P.
(2015)
Lack of galectin-3 prevents cardiac fibrosis and effective immune responses in a murine model of Trypanosoma cruzi infection.
Journal of Infectious Diseases, 212(7),
pp. 1160-1171.
(doi: 10.1093/infdis/jiv185)
(PMID:25805753)
Rzepecka, J. et al.
(2015)
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome.
Journal of Autoimmunity, 60,
pp. 59-73.
(doi: 10.1016/j.jaut.2015.04.005)
(PMID:25975491)
(PMCID:PMC4459730)
Pineda, M.A. , Eason, R.J., Harnett, M.M. and Harnett, W.
(2015)
From the worm to the pill, the parasitic worm product ES-62 raises new horizons in the treatment of rheumatoid arthritis.
Lupus, 24(4-5),
pp. 400-411.
(doi: 10.1177/0961203314560004)
(PMID:25801883)
Rodgers, D. T., McGrath, M. A., Pineda, M. A. , Al-Riyami, L., Rzepecka, J., Lumb, F., Harnett, W. and Harnett, M. M.
(2015)
The parasitic worm product, ES-62 targets MyD88-dependent effector mechanisms to suppress ANA production and proteinuria in MRL/Lpr mice.
Arthritis and Rheumatology, 67(4),
pp. 1023-1035.
(doi: 10.1002/art.39004)
(PMID:25546822)
(PMCID:PMC4409857)
Pineda, M.A. , Corvo, L., Soto, M., Fresno, M. and Bonay, P.
(2015)
Interactions of human galectins with Trypanosoma cruzi: vinding profile correlate with genetic clustering of lineages.
Glycobiology, 25(2),
pp. 197-210.
(doi: 10.1093/glycob/cwu103)
(PMID:25267603)
2014
Pineda, M. A. , Al-Riyami, L., Harnett, W. and Harnett, M. M.
(2014)
Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis.
Clinical and Experimental Immunology, 177(1),
pp. 13-23.
(doi: 10.1111/cei.12252)
(PMID:24666108)
(PMCID:PMC4089150)
Pineda, M. A. , Rodgers, D. T., Al-Riyami, L., Harnett, W. and Harnett, M. M.
(2014)
ES-62 protects against collagen-induced arthritis by resetting IL-22 towards resolution of inflammation in the joints.
Arthritis and Rheumatology, 66(6),
pp. 1492-1503.
(doi: 10.1002/art.38392)
(PMID:24497523)
Pineda, M. A. , Lumb, F., Harnett, M. M. and Harnett, W.
(2014)
ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae.
Molecular and Biochemical Parasitology, 194(1-2),
pp. 1-8.
(doi: 10.1016/j.molbiopara.2014.03.003)
Rodgers, D.T., Pineda, M.A. , McGrath, M.A., Al-Riyami, L., Harnett, W. and Harnett, M.M.
(2014)
Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.
Immunology, 141(3),
pp. 457-466.
(doi: 10.1111/imm.12208)
(PMID:24708419)
(PMCID:PMC3930382)
Harnett, M. , Harnett, W. and Pineda, M. A.
(2014)
The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis.
Inflammation and Cell Signaling, 1(5),
e308.
(doi: 10.14800/ics.308)
2013
Al-Riyami, L., Pineda, M.A. , Rzepecka, J., Huggan, J.K., Khalaf, A.I., Suckling, C.J., Scott, F.J., Rodgers, D.T., Harnett, M.M. and Harnett, W.
(2013)
Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the acanthocheilonema viteae product es-62 prevents development of collagen-induced arthritis.
Journal of Medicinal Chemistry, 56(24),
pp. 9982-10002.
(doi: 10.1021/jm401251p)
2012
Pineda, M.A. , McGrath, M.A., Smith, P.C., Al-Riyami, L., Rzepecka, J., Gracie, J.A., Harnett, W. and Harnett, M.M.
(2012)
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites.
Arthritis and Rheumatism, 64(10),
pp. 3168-3178.
(doi: 10.1002/art.34581)
(PMID:22729944)
This list was generated on Mon Mar 1 14:18:30 2021 GMT.