Dr Karl Burgess

  • Honorary Senior Lecturer (School of Infection & Immunity)

email: Karl.Burgess@glasgow.ac.uk

Room 211, Tcrc, Garscube Campus, Glasgow G61 1QH

Import to contacts

Publications

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Jump to: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009
Number of items: 81.

2023

Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)

Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)

2022

Cortada‐Garcia, J., Haggarty, J., Moses, T., Daly, R. , Arnold, S. A. and Burgess, K. (2022) On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process. Biotechnology and Bioengineering, 119(10), pp. 2757-2769. (doi: 10.1002/bit.28173) (PMID:35798686) (PMCID:PMC9541951)

Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)

Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)

2021

Nile, D. L., Rae, C. , Walker, D. J. , Canning Waddington, J., Vincent, I. , Burgess, K., Gaze, M. N., Mairs, R. J. and Chalmers, A. J. (2021) Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells. Cancer and Metabolism, 9, 24. (doi: 10.1186/s40170-021-00258-5) (PMID:34011385) (PMCID:PMC8136224)

McLuskey, K., Wandy, J. , Vincent, I. , Van Der Hooft, J. J.J. , Rogers, S. , Burgess, K. and Daly, R. (2021) Ranking metabolite sets by their activity levels. Metabolites, 11(2), 103. (doi: 10.3390/metabo11020103) (PMID:33670102) (PMCID:PMC7916825)

Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)

2020

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)

Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)

Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Burgon, J. D. , Vieites, D. R., Jacobs, A. , Weidt, S. K., Gunter, H. M., Steinfartz, S., Burgess, K., Marble, B. K. and Elmer, K. R. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. Molecular Ecology, 29(7), pp. 1284-1299. (doi: 10.1111/mec.15411) (PMID:32159878)

2019

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)

Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

2018

van der Hooft, J. J.J., Alghefari, W., Watson, E., Everest, P. , Morton, F. R. , Burgess, K. E.V. and Smith, D. G.E. (2018) Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose. Metabolomics, 14(11), 144. (doi: 10.1007/s11306-018-1438-5) (PMID:30830405) (PMCID:PMC6208705)

Megalios, A., Daly, R. and Burgess, K. (2018) MetaboCraft: building a Minecraft plugin for metabolomics. Bioinformatics, 34(15), pp. 2693-2694. (doi: 10.1093/bioinformatics/bty102) (PMID:29608638) (PMCID:PMC6061834)

Newton, J., Ramage, G. , Gadegaard, N. , Zachs, W., Rogers, S. , Barrett, M. P. , Carruthers, G. and Burgess, K. (2018) Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts. Scientific Reports, 8, 10944. (doi: 10.1038/s41598-018-28810-2) (PMID:30050048) (PMCID:PMC6062563)

2017

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi: 10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

Gloaguen, Y. , Morton, F. , Daly, R. , Gurden, R., Rogers, S. , Wandy, J. , Wilson, D., Barrett, M. and Burgess, K. (2017) PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data. Bioinformatics, 33(24), pp. 4007-4009. (doi: 10.1093/bioinformatics/btx499) (PMID:28961954) (PMCID:PMC5860087)

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

Zambelloni, R., Connolly, J. P.R., Huerta Uribe, A. , Burgess, K., Marquez, R. and Roe, A. J. (2017) Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition. Molecular Microbiology, 105(4), pp. 606-619. (doi: 10.1111/mmi.13719) (PMID:28557017) (PMCID:PMC5575525)

Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)

Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)

van der Hooft, J. J.J. , Wandy, J. , Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi: 10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)

Kean, R. et al. (2017) Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions. Frontiers in Microbiology, 8, 258. (doi: 10.3389/fmicb.2017.00258)

Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)

Haggarty, J. and Burgess, K. E.V. (2017) Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome. Current Opinion in Biotechnology, 43, pp. 77-85. (doi: 10.1016/j.copbio.2016.09.006) (PMID:27771607)

Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)

2016

Weidt, S., Haggarty, J., Kean, R., Cojocariu, C. I., Silcock, P. J., Rajendran, R., Ramage, G. and Burgess, K. E. V. (2016) A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms. Metabolomics, 12, 189. (doi: 10.1007/s11306-016-1134-2) (PMID:28003796) (PMCID:PMC5097782)

van Der Hooft, J. J. J. , Wandy, J. , Barrett, M. P. , Burgess, K. E.V. and Rogers, S. (2016) Topic modeling for untargeted substructure exploration in metabolomics. Proceedings of the National Academy of Sciences of the United States of America, 113(48), pp. 13738-13743. (doi: 10.1073/pnas.1608041113) (PMID:27856765) (PMCID:PMC5137707)

Rajendran, R. et al. (2016) Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping. Scientific Reports, 6, 35436. (doi: 10.1038/srep35436) (PMID:27765942) (PMCID:PMC5073228)

Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)

Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)

Van Der Hooft, J. , Padmanabhan, S. , Burgess, K. and Barrett, M. (2016) Erratum to: Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12(8), 139. (doi: 10.1007/s11306-016-1078-6)

Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)

Van Der Hooft, J. J.J. , Padmanabhan, S. , Burgess, K. E.V. and Barrett, M. P. (2016) Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12, 125. (doi: 10.1007/s11306-016-1064-z) (PMID:27471437) (PMCID:PMC4932139)

Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)

2015

Kim, D.-H., Achcar, F. , Breitling, R. , Burgess, K. E. and Barrett, M. P. (2015) LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes. Metabolomics, 11(6), pp. 1721-1732. (doi: 10.1007/s11306-015-0827-2) (PMID:26491423) (PMCID:PMC4605981)

Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)

Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J. , Beatson, S. A., Vollmer, W., Smith, D. G.E. and Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242) (PMID:25526369) (PMCID:PMC4366372)

Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)

van der Hooft, J. , Ridder, L., Barrett, M. P. and Burgess, K. V. (2015) Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines. Frontiers in Bioengineering and Biotechnology, 3, p. 26. (doi: 10.3389/fbioe.2015.00026) (PMID:25806366) (PMCID:PMC4353373)

Alkhaldi, A.A.M., Creek, D.J., Ibrahim, H., Kim, D.-H., Quashie, N.B., Burgess, K.E., Changtam, C., Barrett, M.P. , Suksamrarn, A. and De Koning, H.P. (2015) Potent Trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with Trypanothione. Molecular Pharmacology, 87(3), pp. 451-464. (doi: 10.1124/mol.114.096016) (PMID:25527638)

McNamara, L. E., Turner, L.-A. and Burgess, K. V. (2015) Systems biology approaches applied to regenerative medicine. Current Pathobiology Reports, 3(1), pp. 37-45. (doi: 10.1007/s40139-015-0072-4) (PMID:25722955) (PMCID:PMC4333234)

Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.

2014

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi: 10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)

Daly, R. , Rogers, S. , Wandy, J., Jankevics, A., Burgess, K. E.V. and Breitling, R. (2014) MetAssign: probabilistic annotation of metabolites from LC–MS data using a Bayesian clustering approach. Bioinformatics, 30(19), pp. 2764-2771. (doi: 10.1093/bioinformatics/btu370) (PMID:24916385) (PMCID:PMC4173012)

Evans, S., Burgess, K. E.V. and Gray, J. V. (2014) Recovery from Rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (torc1) supports residual proliferation that dilutes rapamycin among progeny cells. Journal of Biological Chemistry, 289(38), pp. 26554-26565. (doi: 10.1074/jbc.M114.589754) (PMID:25104356) (PMCID:PMC4176226)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)

Vincent, I. M. , Weidt, S., Rivas, L., Burgess, K., Smith, T. K. and Ouellette, M. (2014) Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism. International Journal for Parasitology: Drugs and Drug Resistance, 4(1), pp. 20-27. (doi: 10.1016/j.ijpddr.2013.11.002) (PMID:24596665) (PMCID:PMC3940234)

Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)

Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi: 10.1016/B978-0-12-386882-4.00010-4)

2013

Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Burgess, K. and Hundal, H. S. (2013) Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle. Diabetes, 62(10), pp. 3426-3436. (doi: 10.2337/db13-0264) (PMID:23733201) (PMCID:PMC3781443)

Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)

Ali, J.A.M., Creek, D.J., Burgess, K., Allison, H.C., Field, M.C., Maser, P. and De Koning, H.P. (2013) Pyrimidine salvage in trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Molecular Pharmacology, 83(2), pp. 439-453. (doi: 10.1124/mol.112.082321) (PMID:23188714)

Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.

Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)

2012

Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)

Creek, D.J., Chokkathukalam, A., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation. Analytical Chemistry, 84(20), pp. 8442-8447. (doi: 10.1021/ac3018795) (PMID:22946681) (PMCID:PMC3472505)

Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)

Lockman, K.A. et al. (2012) Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. Liver International, 32(7), pp. 1079-1092. (doi: 10.1111/j.1478-3231.2012.02775.x)

Creek, D.J., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) IDEOM: an excel interface for analysis of LC-MS based metabolomics data. Bioinformatics, 28(7), pp. 1048-1049. (doi: 10.1093/bioinformatics/bts069) (PMID:22308147)

Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.

Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.

Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)

2011

Burgess, K., Creek, D., Dewsbury, P., Cook, K. and Barrett, M.P. (2011) Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3447-3452. (doi: 10.1002/rcm.5247)

Leader, D.P. , Burgess, K., Creek, D. and Barrett, M.P. (2011) Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3422-3426. (doi: 10.1002/rcm.5245)

McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)

McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)

Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.

Creek, D.J., Jankevics, A., Breitling, R. , Watson, D.G., Barrett, M.P. and Burgess, K.E.V. (2011) Toward global metabolomics snalysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: improved metabolite identification by retention time prediction. Analytical Chemistry, 83(22), pp. 8703-8710. (doi: 10.1021/ac2021823)

Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.

2010

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)

2009

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)

This list was generated on Thu Apr 18 06:55:36 2024 BST.
Number of items: 81.

Articles

Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)

Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)

Cortada‐Garcia, J., Haggarty, J., Moses, T., Daly, R. , Arnold, S. A. and Burgess, K. (2022) On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process. Biotechnology and Bioengineering, 119(10), pp. 2757-2769. (doi: 10.1002/bit.28173) (PMID:35798686) (PMCID:PMC9541951)

Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)

Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)

Nile, D. L., Rae, C. , Walker, D. J. , Canning Waddington, J., Vincent, I. , Burgess, K., Gaze, M. N., Mairs, R. J. and Chalmers, A. J. (2021) Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells. Cancer and Metabolism, 9, 24. (doi: 10.1186/s40170-021-00258-5) (PMID:34011385) (PMCID:PMC8136224)

McLuskey, K., Wandy, J. , Vincent, I. , Van Der Hooft, J. J.J. , Rogers, S. , Burgess, K. and Daly, R. (2021) Ranking metabolite sets by their activity levels. Metabolites, 11(2), 103. (doi: 10.3390/metabo11020103) (PMID:33670102) (PMCID:PMC7916825)

Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)

Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)

Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Burgon, J. D. , Vieites, D. R., Jacobs, A. , Weidt, S. K., Gunter, H. M., Steinfartz, S., Burgess, K., Marble, B. K. and Elmer, K. R. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. Molecular Ecology, 29(7), pp. 1284-1299. (doi: 10.1111/mec.15411) (PMID:32159878)

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)

Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

van der Hooft, J. J.J., Alghefari, W., Watson, E., Everest, P. , Morton, F. R. , Burgess, K. E.V. and Smith, D. G.E. (2018) Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose. Metabolomics, 14(11), 144. (doi: 10.1007/s11306-018-1438-5) (PMID:30830405) (PMCID:PMC6208705)

Megalios, A., Daly, R. and Burgess, K. (2018) MetaboCraft: building a Minecraft plugin for metabolomics. Bioinformatics, 34(15), pp. 2693-2694. (doi: 10.1093/bioinformatics/bty102) (PMID:29608638) (PMCID:PMC6061834)

Newton, J., Ramage, G. , Gadegaard, N. , Zachs, W., Rogers, S. , Barrett, M. P. , Carruthers, G. and Burgess, K. (2018) Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts. Scientific Reports, 8, 10944. (doi: 10.1038/s41598-018-28810-2) (PMID:30050048) (PMCID:PMC6062563)

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi: 10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

Gloaguen, Y. , Morton, F. , Daly, R. , Gurden, R., Rogers, S. , Wandy, J. , Wilson, D., Barrett, M. and Burgess, K. (2017) PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data. Bioinformatics, 33(24), pp. 4007-4009. (doi: 10.1093/bioinformatics/btx499) (PMID:28961954) (PMCID:PMC5860087)

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

Zambelloni, R., Connolly, J. P.R., Huerta Uribe, A. , Burgess, K., Marquez, R. and Roe, A. J. (2017) Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition. Molecular Microbiology, 105(4), pp. 606-619. (doi: 10.1111/mmi.13719) (PMID:28557017) (PMCID:PMC5575525)

Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)

Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)

van der Hooft, J. J.J. , Wandy, J. , Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi: 10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)

Kean, R. et al. (2017) Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions. Frontiers in Microbiology, 8, 258. (doi: 10.3389/fmicb.2017.00258)

Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)

Haggarty, J. and Burgess, K. E.V. (2017) Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome. Current Opinion in Biotechnology, 43, pp. 77-85. (doi: 10.1016/j.copbio.2016.09.006) (PMID:27771607)

Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)

Weidt, S., Haggarty, J., Kean, R., Cojocariu, C. I., Silcock, P. J., Rajendran, R., Ramage, G. and Burgess, K. E. V. (2016) A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms. Metabolomics, 12, 189. (doi: 10.1007/s11306-016-1134-2) (PMID:28003796) (PMCID:PMC5097782)

van Der Hooft, J. J. J. , Wandy, J. , Barrett, M. P. , Burgess, K. E.V. and Rogers, S. (2016) Topic modeling for untargeted substructure exploration in metabolomics. Proceedings of the National Academy of Sciences of the United States of America, 113(48), pp. 13738-13743. (doi: 10.1073/pnas.1608041113) (PMID:27856765) (PMCID:PMC5137707)

Rajendran, R. et al. (2016) Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping. Scientific Reports, 6, 35436. (doi: 10.1038/srep35436) (PMID:27765942) (PMCID:PMC5073228)

Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)

Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)

Van Der Hooft, J. , Padmanabhan, S. , Burgess, K. and Barrett, M. (2016) Erratum to: Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12(8), 139. (doi: 10.1007/s11306-016-1078-6)

Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)

Van Der Hooft, J. J.J. , Padmanabhan, S. , Burgess, K. E.V. and Barrett, M. P. (2016) Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12, 125. (doi: 10.1007/s11306-016-1064-z) (PMID:27471437) (PMCID:PMC4932139)

Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)

Kim, D.-H., Achcar, F. , Breitling, R. , Burgess, K. E. and Barrett, M. P. (2015) LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes. Metabolomics, 11(6), pp. 1721-1732. (doi: 10.1007/s11306-015-0827-2) (PMID:26491423) (PMCID:PMC4605981)

Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)

Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J. , Beatson, S. A., Vollmer, W., Smith, D. G.E. and Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242) (PMID:25526369) (PMCID:PMC4366372)

Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)

van der Hooft, J. , Ridder, L., Barrett, M. P. and Burgess, K. V. (2015) Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines. Frontiers in Bioengineering and Biotechnology, 3, p. 26. (doi: 10.3389/fbioe.2015.00026) (PMID:25806366) (PMCID:PMC4353373)

Alkhaldi, A.A.M., Creek, D.J., Ibrahim, H., Kim, D.-H., Quashie, N.B., Burgess, K.E., Changtam, C., Barrett, M.P. , Suksamrarn, A. and De Koning, H.P. (2015) Potent Trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with Trypanothione. Molecular Pharmacology, 87(3), pp. 451-464. (doi: 10.1124/mol.114.096016) (PMID:25527638)

McNamara, L. E., Turner, L.-A. and Burgess, K. V. (2015) Systems biology approaches applied to regenerative medicine. Current Pathobiology Reports, 3(1), pp. 37-45. (doi: 10.1007/s40139-015-0072-4) (PMID:25722955) (PMCID:PMC4333234)

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi: 10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)

Daly, R. , Rogers, S. , Wandy, J., Jankevics, A., Burgess, K. E.V. and Breitling, R. (2014) MetAssign: probabilistic annotation of metabolites from LC–MS data using a Bayesian clustering approach. Bioinformatics, 30(19), pp. 2764-2771. (doi: 10.1093/bioinformatics/btu370) (PMID:24916385) (PMCID:PMC4173012)

Evans, S., Burgess, K. E.V. and Gray, J. V. (2014) Recovery from Rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (torc1) supports residual proliferation that dilutes rapamycin among progeny cells. Journal of Biological Chemistry, 289(38), pp. 26554-26565. (doi: 10.1074/jbc.M114.589754) (PMID:25104356) (PMCID:PMC4176226)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)

Vincent, I. M. , Weidt, S., Rivas, L., Burgess, K., Smith, T. K. and Ouellette, M. (2014) Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism. International Journal for Parasitology: Drugs and Drug Resistance, 4(1), pp. 20-27. (doi: 10.1016/j.ijpddr.2013.11.002) (PMID:24596665) (PMCID:PMC3940234)

Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)

Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Burgess, K. and Hundal, H. S. (2013) Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle. Diabetes, 62(10), pp. 3426-3436. (doi: 10.2337/db13-0264) (PMID:23733201) (PMCID:PMC3781443)

Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)

Ali, J.A.M., Creek, D.J., Burgess, K., Allison, H.C., Field, M.C., Maser, P. and De Koning, H.P. (2013) Pyrimidine salvage in trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Molecular Pharmacology, 83(2), pp. 439-453. (doi: 10.1124/mol.112.082321) (PMID:23188714)

Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)

Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)

Creek, D.J., Chokkathukalam, A., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation. Analytical Chemistry, 84(20), pp. 8442-8447. (doi: 10.1021/ac3018795) (PMID:22946681) (PMCID:PMC3472505)

Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)

Lockman, K.A. et al. (2012) Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. Liver International, 32(7), pp. 1079-1092. (doi: 10.1111/j.1478-3231.2012.02775.x)

Creek, D.J., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) IDEOM: an excel interface for analysis of LC-MS based metabolomics data. Bioinformatics, 28(7), pp. 1048-1049. (doi: 10.1093/bioinformatics/bts069) (PMID:22308147)

Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.

Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)

Burgess, K., Creek, D., Dewsbury, P., Cook, K. and Barrett, M.P. (2011) Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3447-3452. (doi: 10.1002/rcm.5247)

Leader, D.P. , Burgess, K., Creek, D. and Barrett, M.P. (2011) Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3422-3426. (doi: 10.1002/rcm.5245)

McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)

McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)

Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.

Creek, D.J., Jankevics, A., Breitling, R. , Watson, D.G., Barrett, M.P. and Burgess, K.E.V. (2011) Toward global metabolomics snalysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: improved metabolite identification by retention time prediction. Analytical Chemistry, 83(22), pp. 8703-8710. (doi: 10.1021/ac2021823)

Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)

Book Sections

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi: 10.1016/B978-0-12-386882-4.00010-4)

Conference or Workshop Item

Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.

Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)

Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.

Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.

This list was generated on Thu Apr 18 06:55:36 2024 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • 2D-based Screening of Effective Synthetic Parts in an Endophytic Fungus for Efficient Production of Enzymes with Post-translation Modifications
    The Royal Society of Edinburgh
    2018 - 2020
     
  • Joint Doctorate in Molecular Animal Nutrition
    European Commission
    2018 - 2022
     
  • Application of omics technology to improve the industrial ABE fermentation from novel sustainable feedstocks
    Scottish Funding Council
    2018 - 2020
     
  • TRIMETHS - A NOVEL URINARY BIOMARKER FOR MINOR STROKE AND TRANSIENT ISCHAEMIC ATTACK
    Chief Scientist Office
    2018 - 2020
     
  • Monitoring biological activity in vegetable waste
    Biotechnology and Biological Sciences Research Council
    2017 - 2018
     
  • FlyMet.org - a tissue-based metabolomic online resource for the Drosophila and systems biology communities
    Biotechnology and Biological Sciences Research Council
    2017 - 2020
     
  • RTMet: Real Time Metabolomics for Synthetic Biology Applications
    Scottish Funding Council
    2017 - 2018
     
  • Extraction and Commercialisation Pathways for Laminaria Hyperborea Bark - 2017-157 IBioIC
    Scottish Funding Council
    2017 - 2018
     
  • Rapid Bone Graft Synthesis Through Dual Piezoelectric/Nanomechaniocal Stimulation
    Biotechnology and Biological Sciences Research Council
    2017 - 2020
     
  • Materials exploitation of the biointerface to control MSC quality and niche phenotype
    Biotechnology and Biological Sciences Research Council
    2017 - 2019
     
  • In-silico quantification of metabolites, lipids and lipoproteins measured by NMR spectroscopy
    Wellcome Trust
    2016 - 2017
     
  • Developing the NanoKick bioreactor to enable tissue engineered bone graft and use of metabolomics to identify bone specific drug candidates
    Engineering and Physical Sciences Research Council
    2016 - 2019
     
  • ISSF Catalyst: Integrative polyomics approach to identify metabolomic and genomic signatures of glioma stem cells for therapeutic intervention in glioblastoma
    Wellcome Trust
    2016 - 2016
     
  • Enhanced interpretation of metabolomics data to accelerate microbial engineering
    Innovate UK
    2015 - 2017
     
  • Ancestry and biological informative markers for stratification of hypertension - The AIM HY study
    Medical Research Council
    2015 - 2020
     
  • BEACONS: Biophoton Emission and Counting for Novel Diagnostics
    Heriot Watt University
    2014 - 2016
     
  • Validation of metabolomics as a technique to identify determinants of treatment response in HCV infection (ISSF Catalyst)
    Wellcome Trust
    2014 - 2015
     
  • Biomarker Discovery 2.0 - Rigorous and Robust Metabolite Characterization using Mass Spectrometry Fragmentation approaches (ISSF Fellowship)
    Wellcome Trust
    2014 - 2015
     
  • Synergistic microenvironments for non-union bone defects
    Medical Research Council
    2014 - 2016
     
  • Nanopatterned Human Liver BioChips for Drug Hepatotoxicity Screening.
    Biotechnology and Biological Sciences Research Council
    2014 - 2016
     
  • Development of nanopatterned substrates for the delivery of high quality stem cells
    Biotechnology and Biological Sciences Research Council
    2013 - 2016
     
  • The implant microbiome: metagenomics and metabolomics to understand the role of co-infection in orthopaedic surgery and medical implantation
    Scottish Government
    2013 - 2014
     
  • SULSA Leaders Award
    Scottish Universities Life Sciences Alliance
    2013 - 2015
     
  • Stem Cells metabolomics for bone therapies and tissue engineering.
    Medical Research Council
    2013 - 2016
     
  • Multiscale topographical modulation of cells and bacteria for next generation orthopaedic implants
    Engineering and Physical Sciences Research Council
    2013 - 2016
     
  • Integron and omics based acceleration of industrial strain development
    Biotechnology and Biological Sciences Research Council
    2012 - 2015
     
  • Proteomics and Metabolomics to Help Understand and Improve Recovery in Stroke Survivors.
    The R S Macdonald Charitable Trust
    2012 - 2013
     
  • Can marine calcifying organisms use proteomic responses to adpat to anthropogenic global change? (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     
  • Metabolomic characterisation of clinical biofilms: monitoring of their formation and dispersal on different nanoscale patterned surfaces (ISSF Catalyst)
    Wellcome Trust
    2011 - 2014
     
  • The iomarkers in Stroke Programme; Detecting, Understanding, and Predicting Outcome After Stroke (ISSF Catalyst Fund)
    Wellcome Trust
    2011 - 2014
     

Research datasets

Jump to: 2021 | 2020 | 2017 | 2016 | 2015
Number of items: 11.

2021

Damiati, L. , Tsimbouri, M. , Eales, M., Jayawarna, V., Xiao, Y., Li, P. , Burgess, K., Wells, J., Meek, R.M. D., Oreffo, R. O. C., Nobbs, A., Ramage, G. , Salmeron-Sanchez, M. and Dalby, M. (2021) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. [Data Collection]

2020

Hodgkinson, T., Tsimbouri, M. , Llopis-Hernandez, V. , Campsie, P., Scurr, D., Childs, P., Phillips, D. , Donnelly, S., Wells, J., Salmeron-Sanchez, M. , Burgess, K., Alexander, M., Vassalli, M. , Oreffo, R., Reid, S., France, D. and Dalby, M. (2020) Nanovibrational mesenchymal stem cell stimulation allows detection of highly osteo-specific bioactive metabolites that can be modified for enhanced potency. [Data Collection]

Burgon, J. D., Vieites, D. R., Jacobs, A., Weidt, S., Gunter, H., Steinfartz, S., Burgess, K., Mable, B. and Elmer, K. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. [Data Collection]

Ross, E., Turner, L.-A., Saeed, A., DONNELLY, H., Burgess, K., Blackburn, G., Reynolds, P., Wells, J., Mountford, J., Gadegaard, N. , Oreffo, R., Salmeron-Sanchez, M. and Dalby, M. (2020) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells during large-scale expansion. [Data Collection]

2017

Tsimbouri, P. , Childs, P., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., Gonzalez-Garcia, C., Blackburn, G., Thomas, D., Giraldo, C. V., Biggs, M. J. P., Curtis, A., Salmerón-Sanchez, M., Reid, S. and Dalby, M. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells via a nanovibrational bioreactor. [Data Collection]

Alakpa, E. V., Jayawarna, V., Burgess, K., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improved hyaline cartilage phenotype from pericytes differentiated using tunable peptide hydrogels. [Data Collection]

Alakpa, E. V., Burgess, K., Chung, P., Riehle, M. , Gadegaard, N. , Dalby, M. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically-induced osteogenesis. [Data Collection]

2016

Lee, L., Gadegaard, N. , Andrés, M. C. d., Turner, L.-A., Burgess, K., Yarwood, S., Wells, J., Mpoyi, E., Salmerón-Sánchez, M., Meek, R. D., Oreffo, R. and Dalby, M. (2016) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. [Data Collection] (Unpublished)

Roberts, J. , Sahoo, J. , McNamara, L., Burgess, K. , Yang, J., Alakpa, E. , Anderson, H. , Hay, J., Turner, L.-A., Yarwood, S., Zelzer, M. , Oreffo, R., Ulijn, R. and Dalby, M. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. [Data Collection] (Unpublished)

Van Der Hooft, J., Rogers, S. , Wandy, J., Barrett, M. and Burgess, K. (2016) Topic Modeling for Untargeted Substructure Exploration in Metabolomics. [Data Collection]

2015

Alakpa, E. V., Jayawarna, V., Burgess, K. V., West, C. C., Bakker, S. C.J., Roy, S., Javid, N., Fleming, S., Lamprou, D. A., Yang, J., Miller, A., Urquhart, A. J., Frederix, P. W.J.M., Hunt, N. T., Péault, B., Ulijn, R. V. and Dalby, M. J. (2015) Using tunable hydrogels for selection of lineage guiding metabolites in stem cell cultures. [Data Collection]

This list was generated on Wed Apr 17 20:32:36 2024 BST.