Dr Elena Sugrue

  • Research Associate (Centre for Virus Research)

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2017 | 2016 | 2015 | 2014
Number of items: 13.

2021

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Ruddell, S., Sugrue, E. , Memarzadeh, S., Hellam, L. M., Wilson, S. and France, D. (2021) Synthesis, enantiomeric resolution and biological evaluation of HIV capsid inhibition activity for racemic, (S)- and (R)-PF74. Molecules, 26(13), 3919. (doi: 10.3390/molecules26133919) (PMID:34206893) (PMCID:PMC8272108)

2020

Sugrue, E. , Coombes, D., Wood, D., Zhu, T., Donovan, K. A. and Dobson, R. C.J. (2020) The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase. European Biophysics Journal, 49, pp. 761-772. (doi: 10.1007/s00249-020-01466-5) (PMID:32978636)

Esquirol, L., Peat, T. S., Sugrue, E. , Balotra, S., Rottet, S., Warden, A. C., Wilding, M., Hartley, C. J., Jackson, C. J. and Scott, C. (2020) Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application. In: Poole, R. K. (ed.) Advances in Microbial Physiology. Volume 76. Elsevier: Amsterdam, pp. 129-186. ISBN 9780128207468 (doi: 10.1016/bs.ampbs.2020.01.004)

2019

Rihn, S. J. et al. (2019) TRIM69 inhibits vesicular stomatitis Indiana virus (VSIV). Journal of Virology, 93(20), e00951-19. (doi: 10.1128/JVI.00951-19) (PMID:31375575)

2017

Sugrue, E. , Scott, C. and Jackson, C.J. (2017) Constrained evolution of a bispecific enzyme: lessons for biocatalyst design. Organic and Biomolecular Chemistry, 15(4), pp. 937-946. (doi: 10.1039/C6OB02355J) (PMID:28054091)

2016

Sugrue, E. , Carr, P. D., Scott, C. and Jackson, C. J. (2016) Active site desolvation and thermostability trade-offs in the evolution of catalytically diverse triazine hydrolases. Biochemistry, 55(45), pp. 6304-6313. (doi: 10.1021/acs.biochem.6b00731) (PMID:27768291)

Sugrue, E. , Hartley, C. J., Scott, C. and Jackson, C. J. (2016) The evolution of new catalytic mechanisms for xenobiotic hydrolysis in bacterial metalloenzymes. Australian Journal of Chemistry, 69(12), pp. 1383-1395. (doi: 10.1071/CH16426)

2015

Sugrue, E. , Fraser, N. J., Hopkins, D. H., Carr, P. D., Khurana, J. L., Oakeshott, J. G., Scott, C., Jackson, C. J. and Nojiri, H. (2015) Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron. Applied and Environmental Microbiology, 81(7), pp. 2612-2624. (doi: 10.1128/AEM.04016-14) (PMID:25636851) (PMCID:PMC4357960)

2014

Jackson, C. J. et al. (2014) 300-fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Applied and Environmental Microbiology, 80(13), pp. 4003-4011. (doi: 10.1128/AEM.00916-14) (PMID:24771025) (PMCID:PMC4054219)

Dobson, R., Naqvi, T., Warden, A. C., French, N., Sugrue, E. , Carr, P. D., Jackson, C. J. and Scott, C. (2014) A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis. PLoS ONE, 9(4), e94177. (doi: 10.1371/journal.pone.0094177) (PMID:24721933) (PMCID:PMC3983157)

This list was generated on Tue Nov 30 22:22:17 2021 GMT.
Number of items: 13.

Articles

Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622)

Shaw, A. E. et al. (2021) The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. PLoS Biology, 19(9), e3001352. (doi: 10.1371/journal.pbio.3001352) (PMID:34491982) (PMCID:PMC8423302)

Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)

Ruddell, S., Sugrue, E. , Memarzadeh, S., Hellam, L. M., Wilson, S. and France, D. (2021) Synthesis, enantiomeric resolution and biological evaluation of HIV capsid inhibition activity for racemic, (S)- and (R)-PF74. Molecules, 26(13), 3919. (doi: 10.3390/molecules26133919) (PMID:34206893) (PMCID:PMC8272108)

Sugrue, E. , Coombes, D., Wood, D., Zhu, T., Donovan, K. A. and Dobson, R. C.J. (2020) The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase. European Biophysics Journal, 49, pp. 761-772. (doi: 10.1007/s00249-020-01466-5) (PMID:32978636)

Rihn, S. J. et al. (2019) TRIM69 inhibits vesicular stomatitis Indiana virus (VSIV). Journal of Virology, 93(20), e00951-19. (doi: 10.1128/JVI.00951-19) (PMID:31375575)

Sugrue, E. , Scott, C. and Jackson, C.J. (2017) Constrained evolution of a bispecific enzyme: lessons for biocatalyst design. Organic and Biomolecular Chemistry, 15(4), pp. 937-946. (doi: 10.1039/C6OB02355J) (PMID:28054091)

Sugrue, E. , Carr, P. D., Scott, C. and Jackson, C. J. (2016) Active site desolvation and thermostability trade-offs in the evolution of catalytically diverse triazine hydrolases. Biochemistry, 55(45), pp. 6304-6313. (doi: 10.1021/acs.biochem.6b00731) (PMID:27768291)

Sugrue, E. , Hartley, C. J., Scott, C. and Jackson, C. J. (2016) The evolution of new catalytic mechanisms for xenobiotic hydrolysis in bacterial metalloenzymes. Australian Journal of Chemistry, 69(12), pp. 1383-1395. (doi: 10.1071/CH16426)

Sugrue, E. , Fraser, N. J., Hopkins, D. H., Carr, P. D., Khurana, J. L., Oakeshott, J. G., Scott, C., Jackson, C. J. and Nojiri, H. (2015) Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron. Applied and Environmental Microbiology, 81(7), pp. 2612-2624. (doi: 10.1128/AEM.04016-14) (PMID:25636851) (PMCID:PMC4357960)

Jackson, C. J. et al. (2014) 300-fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Applied and Environmental Microbiology, 80(13), pp. 4003-4011. (doi: 10.1128/AEM.00916-14) (PMID:24771025) (PMCID:PMC4054219)

Dobson, R., Naqvi, T., Warden, A. C., French, N., Sugrue, E. , Carr, P. D., Jackson, C. J. and Scott, C. (2014) A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis. PLoS ONE, 9(4), e94177. (doi: 10.1371/journal.pone.0094177) (PMID:24721933) (PMCID:PMC3983157)

Book Sections

Esquirol, L., Peat, T. S., Sugrue, E. , Balotra, S., Rottet, S., Warden, A. C., Wilding, M., Hartley, C. J., Jackson, C. J. and Scott, C. (2020) Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application. In: Poole, R. K. (ed.) Advances in Microbial Physiology. Volume 76. Elsevier: Amsterdam, pp. 129-186. ISBN 9780128207468 (doi: 10.1016/bs.ampbs.2020.01.004)

This list was generated on Tue Nov 30 22:22:17 2021 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Identifying the Host and Viral Determinants of Coronavirus Emergence and Adaptation in Human Populations
    Medical Research Council
    2020 - 2023
     

Research datasets

Jump to: 2021
Number of items: 2.

2021

Wickenhagen, A., Sugrue, E. , Lytras, S., Kuchi, S., Noerenberg, M. , Turnbull, M. , Loney, C. , Herder, V., Allan, J., Jarmson, I., Cameron Ruiz, N., Varjak, M. , Pinto, R. , Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D., Swingler, S., Greenwood, E. J. D., Crozier, T. W. M., Gu, Q. , Davies, E., Clohisey, S., Wang, B., Trindade Maranhã Costa, F., Santana, M. F., Carlos de Lima Ferreira, L., Murphy, L., Fawkes, A., Meynert, A., Grimes, G., ISARICC investigators, , Da Silva Filho, J. , Marti, M. , Hughes, J. , Stanton, R. J., Wang, E. C. Y., Ho, A. , Davis, I., Jarrett, R. , Castello, A. , Robertson, D. , Semple, M. G., Openshaw, P. J. M., Palmarini, M. , Lehner, P. J., Baillie, K., Rihn, S. and Wilson, S. (2021) A Prenylated dsRNA Sensor Protects Against Severe COVID-19. [Data Collection]

Shaw, A., Rihn, S. , Mollentze, N. , Wickenhagen, A., Stewart, D., Orton, R. , Kuchi, S., Bakshi, S., Collados Rodriguez, M. , Turnbull, M. , Busby, J. , Gu, Q. , Smollett, K., Bamford, C., Sugrue, E. , Johnson, P. , Da Silva Filipe, A. , Castello, A. , Streicker, D. , Robertson, D. , Palmarini, M. and Wilson, S. (2021) The 'antiviral state' has shaped the CpG composition of the vertebrate interferome to avoid self-targeting. [Data Collection] (Unpublished)

This list was generated on Wed Dec 1 01:59:41 2021 GMT.