Dr Betty Lau

  • Affiliate (Institute of Infection Immunity & Inflammation)

email: Betty.Lau@glasgow.ac.uk

MRC-University of Glasgow Centre for Virus Research, Sir Michael Stoker Building, Garscube Campus, 464 Bearsden Road, G61 1QH

ORCID iDhttps://orcid.org/0000-0003-1382-9830

Research interests

CVR logo 

Member of the Davison Group.

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2018 | 2017 | 2016 | 2015 | 2012
Number of items: 13.

2021

Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, (doi: 10.1128/JVI.00698-21) (PMID:34346763) (Early Online Publication)

2020

Lau, B. , Kerr, K., Gu, Q. , Nightingale, K., Antrobus, R., Suarez, N. M., Stanton, R. J., Wang, E. C., Weekes, M. P. and Davison, A. J. (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)

Tai-Schmiedel, J. et al. (2020) Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication. PLoS Pathogens, 16(4), e1008390. (doi: 10.1371/journal.ppat.1008390) (PMID:32294138) (PMCID:PMC7185721)

2018

Wang, E. C.Y. et al. (2018) Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proceedings of the National Academy of Sciences of the United States of America, 115(19), pp. 4998-5003. (doi: 10.1073/pnas.1720950115) (PMID:29691324) (PMCID:PMC5948980)

2017

Suárez, N. M., Lau, B. , Kemble, G. M., Lee, R., Mocarski, E. S., Wilkinson, G. W.G., Adler, S. P., McVoy, M. A. and Davison, A. J. (2017) Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo. Virus Genes, 53(4), pp. 650-655. (doi: 10.1007/s11262-017-1452-0) (PMID:28391502) (PMCID:PMC5527331)

Krishna, B.A., Spiess, K., Poole, E.L., Lau, B. , Voigt, S., Kledal, T.N., Rosenkilde, M.M. and Sinclair, J.H. (2017) Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein. Nature Communications, 8, 14321. (doi: 10.1038/ncomms14321) (PMID:28148951) (PMCID:PMC5296658)

Beelontally, R. et al. (2017) Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Research, 138, pp. 61-67. (doi: 10.1016/j.antiviral.2016.12.006) (PMID:27956134) (PMCID:PMC5244968)

2016

Lau, B. , Poole, E., Van Damme, E., Bunkens, L., Sowash, M., King, H., Murphy, E., Wills, M., Van Loock, M. and Sinclair, J. (2016) Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells. Journal of General Virology, 97(9), pp. 2387-2398. (doi: 10.1099/jgv.0.000546) (PMID:27411311)

Krishna, B.A., Lau, B. , Jackson, S.E., Wills, M.R., Sinclair, J.H. and Poole, E. (2016) Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells. Scientific Reports, 6, 24674. (doi: 10.1038/srep24674) (PMID:27091512) (PMCID:PMC4835774)

Lau, B. , Poole, E., Krishna, B., Montanuy, I., Wills, M. R., Murphy, E. and Sinclair, J. (2016) The expression of human cytomegalovirus MicroRNA MiR-UL148D during latent infection in primary myeloid cells inhibits Activin A-triggered secretion of IL-6. Scientific Reports, 6, 31205. (doi: 10.1038/srep31205) (PMID:27491954) (PMCID:PMC4974560)

2015

Van Damme, E., Sauviller, S., Lau, B. , Kesteleyn, B., Griffiths, P., Burroughs, A., Emery, V., Sinclair, J. and Van Loock, M. (2015) Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients. Journal of General Virology, 96(1), pp. 131-143. (doi: 10.1099/vir.0.069872-0) (PMID:25312585) (PMCID:PMC4268819)

Wills, M. R., Poole, E., Lau, B. , Krishna, B. and Sinclair, J. H. (2015) The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies? Cellular and Molecular Immunology, 12(2), pp. 128-138. (doi: 10.1038/cmi.2014.75) (PMID:25132454) (PMCID:PMC4654298)

2012

Williams, E. L. et al. (2012) Development and characterisation of monoclonal antibodies specific for the murine inhibitory FcγRIIB (CD32B). European Journal of Immunology, 42(8), pp. 2109-2120. (doi: 10.1002/eji.201142302) (PMID:22760702)

This list was generated on Fri Oct 22 01:37:35 2021 BST.
Jump to: Articles
Number of items: 13.

Articles

Lau, B. et al. (2021) Human cytomegalovirus RNA2.7 is required for upregulating multiple cellular genes to promote cell motility and viral spread late in lytic infection. Journal of Virology, (doi: 10.1128/JVI.00698-21) (PMID:34346763) (Early Online Publication)

Lau, B. , Kerr, K., Gu, Q. , Nightingale, K., Antrobus, R., Suarez, N. M., Stanton, R. J., Wang, E. C., Weekes, M. P. and Davison, A. J. (2020) Human cytomegalovirus long non-coding RNA1.2 suppresses extracellular release of the pro-inflammatory cytokine IL-6 by blocking NF-κB activation. Frontiers in Cellular and Infection Microbiology, 10, 361. (doi: 10.3389/fcimb.2020.00361) (PMID:32793512)

Tai-Schmiedel, J. et al. (2020) Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication. PLoS Pathogens, 16(4), e1008390. (doi: 10.1371/journal.ppat.1008390) (PMID:32294138) (PMCID:PMC7185721)

Wang, E. C.Y. et al. (2018) Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proceedings of the National Academy of Sciences of the United States of America, 115(19), pp. 4998-5003. (doi: 10.1073/pnas.1720950115) (PMID:29691324) (PMCID:PMC5948980)

Suárez, N. M., Lau, B. , Kemble, G. M., Lee, R., Mocarski, E. S., Wilkinson, G. W.G., Adler, S. P., McVoy, M. A. and Davison, A. J. (2017) Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo. Virus Genes, 53(4), pp. 650-655. (doi: 10.1007/s11262-017-1452-0) (PMID:28391502) (PMCID:PMC5527331)

Krishna, B.A., Spiess, K., Poole, E.L., Lau, B. , Voigt, S., Kledal, T.N., Rosenkilde, M.M. and Sinclair, J.H. (2017) Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein. Nature Communications, 8, 14321. (doi: 10.1038/ncomms14321) (PMID:28148951) (PMCID:PMC5296658)

Beelontally, R. et al. (2017) Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Research, 138, pp. 61-67. (doi: 10.1016/j.antiviral.2016.12.006) (PMID:27956134) (PMCID:PMC5244968)

Lau, B. , Poole, E., Van Damme, E., Bunkens, L., Sowash, M., King, H., Murphy, E., Wills, M., Van Loock, M. and Sinclair, J. (2016) Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells. Journal of General Virology, 97(9), pp. 2387-2398. (doi: 10.1099/jgv.0.000546) (PMID:27411311)

Krishna, B.A., Lau, B. , Jackson, S.E., Wills, M.R., Sinclair, J.H. and Poole, E. (2016) Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells. Scientific Reports, 6, 24674. (doi: 10.1038/srep24674) (PMID:27091512) (PMCID:PMC4835774)

Lau, B. , Poole, E., Krishna, B., Montanuy, I., Wills, M. R., Murphy, E. and Sinclair, J. (2016) The expression of human cytomegalovirus MicroRNA MiR-UL148D during latent infection in primary myeloid cells inhibits Activin A-triggered secretion of IL-6. Scientific Reports, 6, 31205. (doi: 10.1038/srep31205) (PMID:27491954) (PMCID:PMC4974560)

Van Damme, E., Sauviller, S., Lau, B. , Kesteleyn, B., Griffiths, P., Burroughs, A., Emery, V., Sinclair, J. and Van Loock, M. (2015) Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients. Journal of General Virology, 96(1), pp. 131-143. (doi: 10.1099/vir.0.069872-0) (PMID:25312585) (PMCID:PMC4268819)

Wills, M. R., Poole, E., Lau, B. , Krishna, B. and Sinclair, J. H. (2015) The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies? Cellular and Molecular Immunology, 12(2), pp. 128-138. (doi: 10.1038/cmi.2014.75) (PMID:25132454) (PMCID:PMC4654298)

Williams, E. L. et al. (2012) Development and characterisation of monoclonal antibodies specific for the murine inhibitory FcγRIIB (CD32B). European Journal of Immunology, 42(8), pp. 2109-2120. (doi: 10.1002/eji.201142302) (PMID:22760702)

This list was generated on Fri Oct 22 01:37:35 2021 BST.