COG-UK One Year On
Issued: Thu, 25 Mar 2021 00:00:00 GMT
The MRC-University of Glasgow Centre for Virus Research (CVR) is part of COG-UK, the COVID-19 Genomics UK consortium. Together we are delivering large-scale, rapid whole-genome sequencing of SARS-CoV-2.
On 23 March 2020, the government announced the launch of a whole genome sequence alliance to map how SARS-CoV-2 spreads and behaves. Backed by the UK’s leading genomic scientists and public health professionals, the COG-UK consortium was established to help better understand the virus and equip public health agencies, the NHS and UK government with the tools to combat COVID-19.
Now, one year on, we are joining our COG-UK partners in reflecting on what we have achieved together and recognising the contributions CVR is making to the consortium.
The consortium has achieved a lot by working together over the past year:
• 373,616* SARS-CoV-2 genomes sequenced in total
• 28,695 — highest number of genomes sequenced in a week
• >1500 genomes sequenced within the first month
• 600+ members & contributors
• 16 academic partners
• 4 public health agencies
• ~60 collaborating organisations
• ~30 international collaborations
• 35 publications
• 15 reports to SAGE
• >£30 million awarded in funding
*as of 24 March 2021.
CVR contributions have been incredibly important in this, and COG-UK research we have contributed to has included:
Travel-related importations of SARS-CoV-2 into Scotland. This work formed part of a SAGE report that has helped to shape travel policy for the UK.
Research on the plasticity of SARS-CoV-2 receptor binding domain – we realised that this meant that the virus could adapt under pressure, heralding the new variants that came later.
Emma Thomson and David Robertson have contributed to several SAGE reports for the government, including reports on hospital outbreaks and on travel-related importations.
Other types of deep analysis we have contributed to with other COG-UK investigators have included: