Dr Naomi Rankin

  • Research Associate (Institute of Cardiovascular & Medical Sciences)
  • Affiliate (Polyomics Facility)

Research interests

Naomi works with Professor Naveed Sattar’s laboratory, which specializes in identifying biomarkers for Cardiovascular Disease and Diabetes Mellitus. This group has implemented the Ala-Korpela method for high-throughput serum/plasma metabolomics using proton Nuclear Magnetic Resonance (NMR) spectroscopy (http://www.computationalmedicine.fi). Naomi is also affiliated with Glasgow Polyomics (http://www.polyomics.gla.ac.uk).

Naomi’s research interests focus on the use of NMR for metabolite profiling and advanced lipoprotein profiling of serum and plasma samples. She is particularly interested in the use of these methods in epidemiology/clinical trials, especially with a view towards translation of NMR molecular profiling approaches into the clinic.

Naomi spent 4 years (2008-2012) working as a pre-registration clinical biochemist at the University Hospital of North Staffordshire. This involved biochemical testing of biological fluids using multiple techniques, interpreting results and advising medical colleagues on the significance of these results, the limitations of the tests and potential further investigations indicated.

She was also seconded to the West Midlands Regional Toxicology Laboratory in Birmingham and the Birmingham Children’s Hospital for specialist training. She passed the part 1 exam for the Royal College of Pathologists in 2012.

Naomi graduated from the University of Strathclyde in 2005 with a BSc (Hons) in Biochemistry and Molecular Biology, for which she was awarded the P.J. Heald memorial prize for biochemistry. She completed an MSc in Clinical Biochemistry and a PhD in Glycobiology (“Immunoglobulin G glycosylation as a biomarker for Multiple Sclerosis”) in 2010 from the University of Birmingham and Strathclyde, respectively.

 Membership:


Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • In-silico quantification of metabolites, lipids and lipoproteins measured by NMR spectroscopy
    Wellcome Trust
    2016 - 2017
     
  • The use of proton nuclear magnetic resonance to investigate dyslipidaemia and small molecule accumulation in chronic kidney disease (ISSF Catalyst)
    Wellcome Trust
    2014 - 2015
     

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2014
Number of items: 8.

2018

Welsh, P. et al. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), pp. 1581-1591. (doi:10.1007/s00125-018-4619-x) (PMID:29728717)

Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi:10.1002/ejhf.1076) (PMID:29226610)

2017

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi:10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

2016

Preiss, D. , Rankin, N. , Welsh, P. , Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M. and Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33(11), pp. 1569-1574. (doi:10.1111/dme.13097) (PMID:26887663)

van der Hooft, J. J.J. and Rankin, N. (2016) Metabolite identification in complex mixtures using nuclear magnetic resonance spectroscopy. In: Webb, G. A. (ed.) Modern Magnetic Resonance. Springer. ISBN 9783319282756 (doi:10.1007/978-3-319-28275-6_6-1)

Rankin, N. J. , Preiss, D. , Welsh, P. and Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45(5), pp. 1351-1371. (doi:10.1093/ije/dyw271) (PMID:27789671) (PMCID:PMC5100629)

2014

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi:10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi:10.1016/B978-0-12-386882-4.00010-4)

This list was generated on Thu Nov 15 16:45:39 2018 GMT.
Number of items: 8.

Articles

Welsh, P. et al. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), pp. 1581-1591. (doi:10.1007/s00125-018-4619-x) (PMID:29728717)

Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi:10.1002/ejhf.1076) (PMID:29226610)

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi:10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

Preiss, D. , Rankin, N. , Welsh, P. , Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M. and Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33(11), pp. 1569-1574. (doi:10.1111/dme.13097) (PMID:26887663)

Rankin, N. J. , Preiss, D. , Welsh, P. and Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45(5), pp. 1351-1371. (doi:10.1093/ije/dyw271) (PMID:27789671) (PMCID:PMC5100629)

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi:10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Book Sections

van der Hooft, J. J.J. and Rankin, N. (2016) Metabolite identification in complex mixtures using nuclear magnetic resonance spectroscopy. In: Webb, G. A. (ed.) Modern Magnetic Resonance. Springer. ISBN 9783319282756 (doi:10.1007/978-3-319-28275-6_6-1)

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi:10.1016/B978-0-12-386882-4.00010-4)

This list was generated on Thu Nov 15 16:45:39 2018 GMT.