Renal Research

Renal Research

Serum Phosphate: Effects on Vascular and Endothelial Function

Patients with chronic kidney disease (CKD) are at greatly increased risk of premature cardiovascular disease. Phosphate, a mineral, is often elevated in CKD and this is a risk factor for cardiovascular disease but the mechanism of action is unclear. Phosphate is modifiable with dietary and drug interventions and is potentially an important therapeutic target to reduce cardiovascular risk in patients with CKD. more

Chronic Kidney Disease

Over the past 15 years, we have used magnetic resonance imaging (MRI) to better define cardiac disease in patients with chronic kidney disease, including those needing dialysis. We have demonstrated that enlargement of the heart muscle (left ventricular hypertrophy) is common, but perhaps less so than previously though.  more

Stroke risk in patients with kidney failure

Patients with end stage renal disease (ESRD) are at increased risk of stroke and cognitive decline, although the mechanisms underpinning this are not fully understood. The timing of this increased risk suggests that factors related to treatment for ESRD (dialysis, transplantation) may be involved. more