New Member of External Scientific Advisory Board
Issued: Mon, 22 Oct 2018 09:22:00 BST
We would like to welcome Professor Christopher Garland as a member of the External Scientific Advisory Board!
Professor Christopher Garland is currently Professor of Vascular Pharmacology at Oxford University and a Fellow and tutor in medicine at Magdalen College. Before moving to Oxford in 2008, he was Professor and Head of Pharmacology in the School of Pharmacy, University of Bath (2000-2008) and before that Reader then Professor of Cardiovascular Pharmacology, University of Bristol (1993-2000). Since 2013, he has been a visiting professor at the University of Queensland, Australia, and held visiting professorships at the University of Bath (2008-12), Nagoya City University Medical School, Japan (2011), Monash University, Australia (2000-2003) and the National Academy of Sciences, Taiwan (2003).
He is an associate editor for Pharmacological Reviews and an editorial board member for Vascular Pharmacology and The Journal of Vascular Research, and previously the British Journal of Pharmacology. He was a Vice-President of the British Pharmacological Society and Council member of the Royal Society of Biology, and has served on grant panels for the Wellcome Trust, British Heart Foundation and the Medical Research Council. In 2009, he was awarded the JR Vane Medal by the British Pharmacological Society, in recognition of his contributions in vascular pharmacology.
His research is concerned with understanding the cellular mechanisms controlling the smallest arteries in our body, enabling them to regulate the pressure and flow of blood. A particular focus has been investigating how the endothelium generates hyperpolarization (EDH) and how it then passes through the artery wall to affect vasodilation. EDH is the predominant vasodilator mechanism in small arteries. He has made seminal contributions in this area, most notably discovering two types of calcium-activated potassium channel are responsible for EDH, that they reside in the endothelium and cluster to form signalling microdomains in endothelial projections, which link with the smooth muscle. Most recent research is probing interactions between intercellular calcium movement and potassium channel activation in the development of vasomotion and vasospasm.