Mr Neil Robertson
- Research Assistant (Paul O'Gorman Leukaemia Research Centre)
Publications
2022
Robertson, N. A. et al. (2022) Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects. Nature Medicine, 28(7), pp. 1439-1446. (doi: 10.1038/s41591-022-01883-3) (PMID:35788175) (PMCID:PMC9307482)
2021
Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)
Latif, A.-L. et al. (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12, 241. (doi: 10.1038/s41467-020-20378-8) (PMID:33431824) (PMCID:PMC7801601)
2020
Terradas-Terradas, M. , Robertson, N. A., Chandra, T. and Kirschner, K. (2020) Clonality in haematopoietic stem cell ageing. Mechanisms of Ageing and Development, 189, 111279. (doi: 10.1016/j.mad.2020.111279) (PMID:32526214) (PMCID:PMC7347006)
Vizioli, M. G. et al. (2020) Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence. Genes and Development, 34(5-6), pp. 428-445. (doi: 10.1101/gad.331272.119) (PMID:32001510) (PMCID:PMC7050483)
MacKenzie, D. J. et al. (2020) DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation. iScience, 23(2), 100838. (doi: 10.1016/j.isci.2020.100838) (PMID:32058953) (PMCID:PMC7000804)
2019
Costa, T. D. F. et al. (2019) PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer. Nature Communications, 10, 3589. (doi: 10.1038/s41467-019-11510-4) (PMID:31399573) (PMCID:PMC6689091)
Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M. , Higham, J., Sproul, D., Deary, I. J., Kirschner, K. , Marioni, R. E. and Chandra, T. (2019) Age-related clonal haemopoiesis is associated with increased epigenetic age. Current Biology, 29(16), R786-R787. (doi: 10.1016/j.cub.2019.07.011) (PMID:31430471)
2017
Cole, J. J. et al. (2017) Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology, 18, 58. (doi: 10.1186/s13059-017-1185-3) (PMID:28351383) (PMCID:PMC5370462)
Wang, T., Tsui, B., Kreisberg, J. F., Robertson, N. A., Gross, A. M., Yu, M. K., Carter, H., Brown-Borg, H. M., Adams, P. D. and Ideker, T. (2017) Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment. Genome Biology, 18, 57. (doi: 10.1186/s13059-017-1186-2) (PMID:28351423) (PMCID:PMC5371228)
2016
Nelson, D. M. et al. (2016) Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biology, 17, 158. (doi: 10.1186/s13059-016-1017-x) (PMID:27457071) (PMCID:PMC4960804)
2015
MacKenzie, D. J., Robertson, N. A., Cole, J. and Adams, P. (2015) Su1996 oncogenic BRAFV600e downregulates DNMT3B and does not directly induce the CpG island hypermethylator phenotype in human colorectal adenocarcinoma. Gastroenterology, 148(4), S570. (doi: 10.1016/S0016-5085(15)31925-9)
Articles
Robertson, N. A. et al. (2022) Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects. Nature Medicine, 28(7), pp. 1439-1446. (doi: 10.1038/s41591-022-01883-3) (PMID:35788175) (PMCID:PMC9307482)
Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)
Latif, A.-L. et al. (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12, 241. (doi: 10.1038/s41467-020-20378-8) (PMID:33431824) (PMCID:PMC7801601)
Terradas-Terradas, M. , Robertson, N. A., Chandra, T. and Kirschner, K. (2020) Clonality in haematopoietic stem cell ageing. Mechanisms of Ageing and Development, 189, 111279. (doi: 10.1016/j.mad.2020.111279) (PMID:32526214) (PMCID:PMC7347006)
Vizioli, M. G. et al. (2020) Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence. Genes and Development, 34(5-6), pp. 428-445. (doi: 10.1101/gad.331272.119) (PMID:32001510) (PMCID:PMC7050483)
MacKenzie, D. J. et al. (2020) DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation. iScience, 23(2), 100838. (doi: 10.1016/j.isci.2020.100838) (PMID:32058953) (PMCID:PMC7000804)
Costa, T. D. F. et al. (2019) PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer. Nature Communications, 10, 3589. (doi: 10.1038/s41467-019-11510-4) (PMID:31399573) (PMCID:PMC6689091)
Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M. , Higham, J., Sproul, D., Deary, I. J., Kirschner, K. , Marioni, R. E. and Chandra, T. (2019) Age-related clonal haemopoiesis is associated with increased epigenetic age. Current Biology, 29(16), R786-R787. (doi: 10.1016/j.cub.2019.07.011) (PMID:31430471)
Cole, J. J. et al. (2017) Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology, 18, 58. (doi: 10.1186/s13059-017-1185-3) (PMID:28351383) (PMCID:PMC5370462)
Wang, T., Tsui, B., Kreisberg, J. F., Robertson, N. A., Gross, A. M., Yu, M. K., Carter, H., Brown-Borg, H. M., Adams, P. D. and Ideker, T. (2017) Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment. Genome Biology, 18, 57. (doi: 10.1186/s13059-017-1186-2) (PMID:28351423) (PMCID:PMC5371228)
Nelson, D. M. et al. (2016) Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biology, 17, 158. (doi: 10.1186/s13059-016-1017-x) (PMID:27457071) (PMCID:PMC4960804)
MacKenzie, D. J., Robertson, N. A., Cole, J. and Adams, P. (2015) Su1996 oncogenic BRAFV600e downregulates DNMT3B and does not directly induce the CpG island hypermethylator phenotype in human colorectal adenocarcinoma. Gastroenterology, 148(4), S570. (doi: 10.1016/S0016-5085(15)31925-9)