Dr Alexei Vazquez

  • Senior Lecturer (Institute of Cancer Sciences)

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2017 | 2016 | 2015 | 2014
Number of items: 24.

2019

McGregor, G. H. et al. (2019) Targeting the metabolic response to statin-mediated oxidative stress produces a synergistic anti-tumor response. Cancer Research, (doi:10.1158/0008-5472.CAN-19-0644) (PMID:31562248) (Early Online Publication)

Pietzke, M., Meiser, J. and Vazquez, A. (2019) Formate metabolism in health and disease. Molecular Metabolism, (doi:10.1016/j.molmet.2019.05.012) (PMID:31402327) (In Press)

Fernandez-de-Cossio-Diaz, J., Mulet, R. and Vazquez, A. (2019) Cell population heterogeneity driven by stochastic partition and growth optimality. Scientific Reports, 9, 9406. (doi:10.1038/s41598-019-45882-w) (PMID:31253860) (PMCID:PMC6599024)

2018

Halim, S., Markert, E. K. and Vazquez, A. (2018) Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer. British Journal of Cancer, 119(7), pp. 855-863. (doi:10.1038/s41416-018-0253-0) (PMID:30287917)

Fernandez-de-Cossio-Diaz, J. and Vazquez Vazquez, A. (2018) A physical model of cell metabolism. Scientific Reports, 8, 8349. (doi:10.1038/s41598-018-26724-7) (PMID:29844352) (PMCID:PMC5974398)

Meiser, J. et al. (2018) Increased formate overflow is a hallmark of oxidative cancer. Nature Communications, 9, 1368. (doi:10.1038/s41467-018-03777-w) (PMID:29636461) (PMCID:PMC5893600)

Vazquez, A. (2018) Overflow Metabolism: From Yeast to Marathon Runners. Academic Press. (doi:10.1016/C2016-0-02486-5)

2017

Fernandez-de-Cossio-Diaz, J. and Vazquez, A. (2017) Limits of aerobic metabolism in cancer cells. Scientific Reports, 7, 13488. (doi:10.1038/s41598-017-14071-y) (PMID:29044214) (PMCID:PMC5647437)

Burgos-Barragan, G. et al. (2017) Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature, 548(7669), pp. 549-554. (doi:10.1038/nature23481) (PMID:28813411) (PMCID:PMC5714256)

Dolfi, S. C. et al. (2017) Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells. Oncotarget, 8(27), pp. 44639-44653. (doi:10.18632/oncotarget.17961) (PMID:28591718) (PMCID:PMC5546507)

Meiser, J., Vazquez, A. and Hiller, K. (2017) DJ1 at the interface between neuro-degeneration and cancer. Oncotarget, 8(6), pp. 9015-9016. (doi:10.18632/oncotarget.14889) (PMID:28147334) (PMCID:PMC5354710)

Bulusu, V. et al. (2017) Acetate recapturing by nuclear acetyl-CoA synthetase 2 prevents loss of histone acetylation during oxygen and serum limitation. Cell Reports, 18(3), pp. 647-658. (doi:10.1016/j.celrep.2016.12.055) (PMID:28099844) (PMCID:5276806)

2016

Meiser, J. et al. (2016) Serine one-carbon catabolism with formate overflow. Science Advances, 2(10), e1601273. (doi:10.1126/sciadv.1601273) (PMID:27819051) (PMCID:PMC5091358)

Meiser, J. and Vazquez, A. (2016) Give it or take it: the flux of one-carbon in cancer cells. FEBS Journal, 283(20), pp. 3695-3704. (doi:10.1111/febs.13731) (PMID:27042806)

Hirshfield, K. M. et al. (2016) Clinical actionability of comprehensive genomic profiling for management of rare or refractory cancers. Oncologist, 21(11), pp. 1315-1325. (doi:10.1634/theoncologist.2016-0049) (PMID:27566247)

Vazquez, A., Kamphorst, J. J. , Markert, E. K., Schug, Z. T., Tardito, S. and Gottlieb, E. (2016) Cancer metabolism at a glance. Journal of Cell Science, 129(18), pp. 3367-3373. (doi:10.1242/jcs.181016) (PMID:27635066)

Vazquez, A. and Oltvai, Z. N. (2016) Macromolecular crowding explains overflow metabolism in cells. Scientific Reports, 6, 31007. (doi:10.1038/srep31007) (PMID:27484619) (PMCID:PMC4971534)

2015

Tedeschi, P.M., Vazquez, A. , Kerrigan, J.E. and Bertino, J.R. (2015) Mitochondrial methylenetetrahydrofolate dehydrogenase (MTHFD2) overexpression is associated with tumor cell proliferation and is a novel target for drug development. Molecular Cancer Research, 13(10), pp. 1361-1366. (doi:10.1158/1541-7786.MCR-15-0117) (PMID:26101208) (PMCID:PMC4618031)

Buescher, J. M. et al. (2015) A roadmap for interpreting 13C metabolite labeling patterns from cells. Current Opinion in Biotechnology, 34, pp. 189-201. (doi:10.1016/j.copbio.2015.02.003) (PMID:25731751) (PMCID:PMC4552607)

Cardaci, S. et al. (2015) Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis. Nature Cell Biology, 17, pp. 1317-1326. (doi:10.1038/ncb3233) (PMID:26302408)

2014

Warita, K., Warita, T., Beckwitt, C. H., Schurdak, M. E., Vazquez, A. , Wells, A. and Oltvai, Z. N. (2014) Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. Scientific Reports, 4, 7593. (doi:10.1038/srep07593) (PMID:25534349) (PMCID:PMC4274516)

Cicchini, M., Chakrabarti, R., Kongara, S., Price, S., Nahar, R., Lozy, F., Zhong, H., Vazquez, A. , Kang, Y. and Karantza, V. (2014) Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy, 10(11), pp. 2036-2052. (doi:10.4161/auto.34398) (PMID:25483966) (PMCID:PMC4502817)

Yu, X., Narayanan, S., Vazquez, A. and Carpizo, D. R. (2014) Small molecule compounds targeting the p53 pathway: are we finally making progress? Apoptosis, 19(7), pp. 1055-1068. (doi:10.1007/s10495-014-0990-3) (PMID:24756955) (PMCID:PMC4039992)

Lozy, F., Cai-McRae, X., Teplova, I., Price, S., Reddy, A., Bhanot, G., Ganesan, S., Vazquez, A. and Karantza, V. (2014) ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelicBecn1loss. Autophagy, 10(4), pp. 662-676. (doi:10.4161/auto.27867) (PMID:24492513) (PMCID:PMC4091153)

This list was generated on Sun Dec 8 09:15:06 2019 GMT.
Jump to: Articles | Books
Number of items: 24.

Articles

McGregor, G. H. et al. (2019) Targeting the metabolic response to statin-mediated oxidative stress produces a synergistic anti-tumor response. Cancer Research, (doi:10.1158/0008-5472.CAN-19-0644) (PMID:31562248) (Early Online Publication)

Pietzke, M., Meiser, J. and Vazquez, A. (2019) Formate metabolism in health and disease. Molecular Metabolism, (doi:10.1016/j.molmet.2019.05.012) (PMID:31402327) (In Press)

Fernandez-de-Cossio-Diaz, J., Mulet, R. and Vazquez, A. (2019) Cell population heterogeneity driven by stochastic partition and growth optimality. Scientific Reports, 9, 9406. (doi:10.1038/s41598-019-45882-w) (PMID:31253860) (PMCID:PMC6599024)

Halim, S., Markert, E. K. and Vazquez, A. (2018) Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer. British Journal of Cancer, 119(7), pp. 855-863. (doi:10.1038/s41416-018-0253-0) (PMID:30287917)

Fernandez-de-Cossio-Diaz, J. and Vazquez Vazquez, A. (2018) A physical model of cell metabolism. Scientific Reports, 8, 8349. (doi:10.1038/s41598-018-26724-7) (PMID:29844352) (PMCID:PMC5974398)

Meiser, J. et al. (2018) Increased formate overflow is a hallmark of oxidative cancer. Nature Communications, 9, 1368. (doi:10.1038/s41467-018-03777-w) (PMID:29636461) (PMCID:PMC5893600)

Fernandez-de-Cossio-Diaz, J. and Vazquez, A. (2017) Limits of aerobic metabolism in cancer cells. Scientific Reports, 7, 13488. (doi:10.1038/s41598-017-14071-y) (PMID:29044214) (PMCID:PMC5647437)

Burgos-Barragan, G. et al. (2017) Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature, 548(7669), pp. 549-554. (doi:10.1038/nature23481) (PMID:28813411) (PMCID:PMC5714256)

Dolfi, S. C. et al. (2017) Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells. Oncotarget, 8(27), pp. 44639-44653. (doi:10.18632/oncotarget.17961) (PMID:28591718) (PMCID:PMC5546507)

Meiser, J., Vazquez, A. and Hiller, K. (2017) DJ1 at the interface between neuro-degeneration and cancer. Oncotarget, 8(6), pp. 9015-9016. (doi:10.18632/oncotarget.14889) (PMID:28147334) (PMCID:PMC5354710)

Bulusu, V. et al. (2017) Acetate recapturing by nuclear acetyl-CoA synthetase 2 prevents loss of histone acetylation during oxygen and serum limitation. Cell Reports, 18(3), pp. 647-658. (doi:10.1016/j.celrep.2016.12.055) (PMID:28099844) (PMCID:5276806)

Meiser, J. et al. (2016) Serine one-carbon catabolism with formate overflow. Science Advances, 2(10), e1601273. (doi:10.1126/sciadv.1601273) (PMID:27819051) (PMCID:PMC5091358)

Meiser, J. and Vazquez, A. (2016) Give it or take it: the flux of one-carbon in cancer cells. FEBS Journal, 283(20), pp. 3695-3704. (doi:10.1111/febs.13731) (PMID:27042806)

Hirshfield, K. M. et al. (2016) Clinical actionability of comprehensive genomic profiling for management of rare or refractory cancers. Oncologist, 21(11), pp. 1315-1325. (doi:10.1634/theoncologist.2016-0049) (PMID:27566247)

Vazquez, A., Kamphorst, J. J. , Markert, E. K., Schug, Z. T., Tardito, S. and Gottlieb, E. (2016) Cancer metabolism at a glance. Journal of Cell Science, 129(18), pp. 3367-3373. (doi:10.1242/jcs.181016) (PMID:27635066)

Vazquez, A. and Oltvai, Z. N. (2016) Macromolecular crowding explains overflow metabolism in cells. Scientific Reports, 6, 31007. (doi:10.1038/srep31007) (PMID:27484619) (PMCID:PMC4971534)

Tedeschi, P.M., Vazquez, A. , Kerrigan, J.E. and Bertino, J.R. (2015) Mitochondrial methylenetetrahydrofolate dehydrogenase (MTHFD2) overexpression is associated with tumor cell proliferation and is a novel target for drug development. Molecular Cancer Research, 13(10), pp. 1361-1366. (doi:10.1158/1541-7786.MCR-15-0117) (PMID:26101208) (PMCID:PMC4618031)

Buescher, J. M. et al. (2015) A roadmap for interpreting 13C metabolite labeling patterns from cells. Current Opinion in Biotechnology, 34, pp. 189-201. (doi:10.1016/j.copbio.2015.02.003) (PMID:25731751) (PMCID:PMC4552607)

Cardaci, S. et al. (2015) Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis. Nature Cell Biology, 17, pp. 1317-1326. (doi:10.1038/ncb3233) (PMID:26302408)

Warita, K., Warita, T., Beckwitt, C. H., Schurdak, M. E., Vazquez, A. , Wells, A. and Oltvai, Z. N. (2014) Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. Scientific Reports, 4, 7593. (doi:10.1038/srep07593) (PMID:25534349) (PMCID:PMC4274516)

Cicchini, M., Chakrabarti, R., Kongara, S., Price, S., Nahar, R., Lozy, F., Zhong, H., Vazquez, A. , Kang, Y. and Karantza, V. (2014) Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy, 10(11), pp. 2036-2052. (doi:10.4161/auto.34398) (PMID:25483966) (PMCID:PMC4502817)

Yu, X., Narayanan, S., Vazquez, A. and Carpizo, D. R. (2014) Small molecule compounds targeting the p53 pathway: are we finally making progress? Apoptosis, 19(7), pp. 1055-1068. (doi:10.1007/s10495-014-0990-3) (PMID:24756955) (PMCID:PMC4039992)

Lozy, F., Cai-McRae, X., Teplova, I., Price, S., Reddy, A., Bhanot, G., Ganesan, S., Vazquez, A. and Karantza, V. (2014) ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelicBecn1loss. Autophagy, 10(4), pp. 662-676. (doi:10.4161/auto.27867) (PMID:24492513) (PMCID:PMC4091153)

Books

Vazquez, A. (2018) Overflow Metabolism: From Yeast to Marathon Runners. Academic Press. (doi:10.1016/C2016-0-02486-5)

This list was generated on Sun Dec 8 09:15:06 2019 GMT.