2024

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, (Accepted for Publication)

Malla, S. B. et al. (2024) Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature Genetics, 56(3), pp. 458-472. (doi: 10.1038/s41588-024-01654-5) (PMID:38351382)

2023

Nikolatou, K. et al. (2023) PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer. EMBO Journal, 42, e1139. (doi: 10.15252/embj.2023113987) (PMID:37577760) (PMCID:PMC10505920)

Edwards, S. C. et al. (2023) PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells. Journal of Experimental Medicine, 220(2), e20211431. (doi: 10.1084/jem.20211431) (PMID:36480166) (PMCID:PMC9732671)

Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)

2022

Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)

Kay, E. J. et al. (2022) Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix. Nature Metabolism, 4(6), pp. 693-710. (doi: 10.1038/s42255-022-00582-0) (PMID:35760868) (PMCID:PMC9236907)

Müller, M. et al. (2022) Human-correlated genetic HCC models identify combination therapy for precision medicine [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1638504/v1)

2021

Tsim, S. et al. (2021) Serum proteomics and plasma fibulin-3 in differentiation of mesothelioma from asbestos-exposed controls and patients with other pleural diseases. Journal of Thoracic Oncology, 16(10), pp. 1705-1717. (doi: 10.1016/j.jtho.2021.05.018) (PMID:34116230) (PMCID:PMC8514249)

2020

Mohan, S. et al. (2020) Profiling of circulating free DNA using targeted and genome-wide sequencing in patients with SCLC. Journal of Thoracic Oncology, 15(2), pp. 216-230. (doi: 10.1016/j.jtho.2019.10.007) (PMID:31629061) (PMCID:PMC7001105)

2019

Chemi, F. et al. (2019) Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse. Nature Medicine, 25(10), pp. 1534-1539. (doi: 10.1038/s41591-019-0593-1) (PMID:31591595) (PMCID:PMC6986897)

Memon, D., Bi, J. and Miller, C. J. (2019) In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival. Scientific Reports, 9, 7372. (doi: 10.1038/s41598-019-43758-7) (PMID:31089191) (PMCID:PMC6517443)

Rothwell, D. G. et al. (2019) Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study. Nature Medicine, 25(5), pp. 738-743. (doi: 10.1038/s41591-019-0380-z) (PMID:31011204)

Parry, M. A. et al. (2019) Genomic evaluation of multiparametric magnetic resonance imaging-visible and -nonvisible lesions in clinically localised prostate cancer. European Urology Oncology, 2(1), pp. 1-11. (doi: 10.1016/j.euo.2018.08.005) (PMID:30929837) (PMCID:PMC6472613)

Lallo, A. et al. (2019) Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics. British Journal of Pharmacology, 176(3), pp. 436-450. (doi: 10.1111/bph.14542) (PMID:30427531) (PMCID:PMC6329630)

2018

Kim, C. S., Mohan, S., Ayub, M., Rothwell, D. G., Dive, C., Brady, G. and Miller, C. (2018) In silico error correction improves cfDNA mutation calling. Bioinformatics, 35(14), pp. 2380-2385. (doi: 10.1093/bioinformatics/bty1004) (PMID:30520956) (PMCID:PMC6612818)

Lallo, A. et al. (2018) The combination of the PARP inhibitor Olaparib and the WEE1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer. Clinical Cancer Research, 24(20), pp. 5153-5164. (doi: 10.1158/1078-0432.CCR-17-2805) (PMID:29941481)

Torres-Ayuso, P. et al. (2018) Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin. npj Genomic Medicine, 3, 15. (doi: 10.1038/s41525-018-0055-6) (PMID:29951225) (PMCID:PMC6010465)

Hudson, A. M. et al. (2018) Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases. Science Signaling, 11(526), eaan6776. (doi: 10.1126/scisignal.aan6776) (PMID:29666306)

Bennett, L., Howell, M., Memon, D., Smowton, C., Zhou, C. and Miller, C. J. (2018) Mutation pattern analysis reveals polygenic mini-drivers associated with relapse after surgery in lung adenocarcinoma. Scientific Reports, 8, 14830. (doi: 10.1038/s41598-018-33276-3) (PMID:30287876) (PMCID:PMC6172282)

2017

Chiu, A., Ayub, M., Dive, C., Brady, G., Miller, C. J. and Hancock, J. (2017) twoddpcr: an R/Bioconductor package and Shiny app for Droplet Digital PCR analysis. Bioinformatics, 33(17), pp. 2743-2745. (doi: 10.1093/bioinformatics/btx308) (PMID:28475662) (PMCID:PMC5860069)

Khandelwal, G. et al. (2017) Next-generation sequencing analysis and algorithms for PDX and CDX models. Molecular Cancer Research, 15(8), pp. 1012-1016. (doi: 10.1158/1541-7786.MCR-16-0431) (PMID:28442585)

Smowton, C., Balla, A., Antoniades, D., Miller, C. , Pallis, G., Dikaiakos, M. D. and Xing, W. (2017) A cost-effective approach to improving performance of big genomic data analyses in clouds. Future Generation Computer Systems, 67, pp. 368-381. (doi: 10.1016/j.future.2015.11.011)

Carter, L. et al. (2017) Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer. Nature Medicine, 23(1), pp. 114-119. (doi: 10.1038/nm.4239) (PMID:27869802)

Draper, J. E., Sroczynska, P., Leong, H. S., Fadlullah, M. Z. H., Miller, C. , Kouskoff, V. and Lacaud, G. (2017) Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors. Blood, 130(3), pp. 271-284. (doi: 10.1182/blood-2016-06-723635) (PMID:28490570) (PMCID:PMC5833261)

2016

Williamson, S. C. et al. (2016) Vasculogenic mimicry in small cell lung cancer. Nature Communications, 7, 13322. (doi: 10.1038/ncomms13322) (PMID:27827359) (PMCID:PMC5105195)

Memon, D., Dawson, K., Smowton, C. S., Xing, W., Dive, C. and Miller, C. J. (2016) Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response. npj Genomic Medicine, 1, 16020. (doi: 10.1038/npjgenmed.2016.20) (PMID:28480052) (PMCID:PMC5417364)

Carter, L. R. et al. (2016) Abstract 3155: Investigating chemoresistance in small cell lung cancer through the molecular profiling of single circulating tumour cells. 107th Annual Meeting of the American Association for Cancer Research - Proceedings, New Orleans, LA. Philadelphia (PA), 16-20 Apr 2016. p. 3155. (doi: 10.1158/1538-7445.AM2016-3155)

Morrow, C.J. et al. (2016) Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study. Annals of Oncology, 27(6), pp. 1155-1160. (doi: 10.1093/annonc/mdw122) (PMID:27013395) (PMCID:PMC4880063)

Tape, C. J. et al. (2016) Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation. Cell, 165(4), pp. 910-920. (doi: 10.1016/j.cell.2016.03.029) (PMID:27087446) (PMCID:PMC4868820)

Rothwell, D. G. et al. (2016) Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample. Molecular Oncology, 10(4), pp. 566-574. (doi: 10.1016/j.molonc.2015.11.006) (PMID:26639657) (PMCID:PMC4834815)

Marusiak, A. A. et al. (2016) Recurrent MLK4 loss-of-function mutations suppress JNK signaling to promote colon tumorigenesis. Cancer Research, 76(3), pp. 724-735. (doi: 10.1158/0008-5472.can-15-0701-t) (PMID:26637668) (PMCID:PMC4740929)

Grimes, H. L., Draper, J. E., Sroczynska, P., Tsoulaki, O., Leong, H. S., Fadlullah, M. Z. H., Miller, C. , Kouskoff, V. and Lacaud, G. (2016) RUNX1B expression is highly heterogeneous and distinguishes megakaryocytic and erythroid lineage fate in adult mouse hematopoiesis. PLoS Genetics, 12(1), e1005814. (doi: 10.1371/journal.pgen.1005814) (PMID:26808730) (PMCID:PMC4726605)

Thambyrajah, R. et al. (2016) GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1. Nature Cell Biology, 18(1), pp. 21-32. (doi: 10.1038/ncb3276) (PMID:26619147)

2015

Liu, J. et al. (2015) Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia. Oncotarget, 6(40), pp. 43048-43064. (doi: 10.18632/oncotarget.5528) (PMID:26474278) (PMCID:PMC4767490)

Antal, C. E. et al. (2015) Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor. Cell, 160(3), pp. 489-502. (doi: 10.1016/j.cell.2015.01.001) (PMID:25619690) (PMCID:PMC4313737)

Hudson, A. M., Wirth, C., Stephenson, N. L., Fawdar, S., Brognard, J. and Miller, C. J. (2015) Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges. Pharmacogenomics, 16(10), pp. 1149-1160. (doi: 10.2217/pgs.15.60) (PMID:26230733)

Smowton, C., Copil, G., Truong, H.-L., Miller, C. and Xing, W. (2015) Genome Analysis in a Dynamically Scaled Hybrid Cloud. In: 2015 IEEE 11th International Conference on e-Science, Munich, Germany, 31 Aug - 4 Sept 2015, pp. 391-400. ISBN 9781467393256 (doi: 10.1109/eScience.2015.17)

Smowton, C., Miller, C. , Xing, W., Balla, A., Antoniades, D., Pallis, G. and Dikaiakos, M. D. (2015) Analysing Cancer Genomics in the Elastic Cloud. In: 2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, Shenzhen, China, 4-7 May 2015, pp. 835-844. (doi: 10.1109/CCGrid.2015.176)

Xing, W., Jie, W. and Miller, C. (2015) SCAN: A Smart Application Platform for Empowering Parallelizations of Big Genomic Data Analysis in Clouds. In: 2015 44th International Conference on Parallel Processing, Beijing, China, 1-4 Sept 2015, pp. 290-299. ISBN 9781467375870 (doi: 10.1109/ICPP.2015.38)

2014

Rothwell, D. G. et al. (2014) Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells. BMC Genomics, 15, 1129. (doi: 10.1186/1471-2164-15-1129) (PMID:25519510) (PMCID:PMC4320548)

Hudson, A. M., Yates, T., Li, Y., Trotter, E. W., Fawdar, S., Chapman, P., Lorigan, P., Biankin, A. , Miller, C. and Brognard, J. (2014) Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery. Cancer Research, 74(22), pp. 6390-6396. (doi: 10.1158/0008-5472.CAN-14-1020) (PMID:25256751)

Lie-A-Ling, M., Marinopoulou, E., Li, Y., Patel, R., Stefanska, M., Bonifer, C., Miller, C., Kouskoff, V. and Lacaud, G. (2014) RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence. Blood, 124(11), e11-e20. (doi: 10.1182/blood-2014-04-572958) (PMID:25082880)

Aboussekhra, A. et al. (2014) Epithelial and stromal MicroRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation. PLoS ONE, 9(8), e105099. (doi: 10.1371/journal.pone.0105099) (PMID:25122196) (PMCID:PMC4133372)

Hodgkinson, C. L. et al. (2014) Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer. Nature Medicine, 20(8), pp. 897-903. (doi: 10.1038/nm.3600) (PMID:24880617)

Leong, H. S., Dawson, K., Wirth, C., Li, Y., Connolly, Y., Smith, D. L., Wilkinson, C. R. M. and Miller, C. J. (2014) A global non-coding RNA system modulates fission yeast protein levels in response to stress. Nature Communications, 5, 3947. (doi: 10.1038/ncomms4947) (PMID:24853205) (PMCID:PMC4050258)

Gires, O. et al. (2014) Investigation of radiosensitivity gene signatures in cancer cell lines. PLoS ONE, 9, e86329. (doi: 10.1371/journal.pone.0086329) (PMID:24466029) (PMCID:PMC3899227)

Articles

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, (Accepted for Publication)

Malla, S. B. et al. (2024) Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature Genetics, 56(3), pp. 458-472. (doi: 10.1038/s41588-024-01654-5) (PMID:38351382)

Nikolatou, K. et al. (2023) PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer. EMBO Journal, 42, e1139. (doi: 10.15252/embj.2023113987) (PMID:37577760) (PMCID:PMC10505920)

Edwards, S. C. et al. (2023) PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells. Journal of Experimental Medicine, 220(2), e20211431. (doi: 10.1084/jem.20211431) (PMID:36480166) (PMCID:PMC9732671)

Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)

Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)

Kay, E. J. et al. (2022) Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix. Nature Metabolism, 4(6), pp. 693-710. (doi: 10.1038/s42255-022-00582-0) (PMID:35760868) (PMCID:PMC9236907)

Müller, M. et al. (2022) Human-correlated genetic HCC models identify combination therapy for precision medicine [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1638504/v1)

Tsim, S. et al. (2021) Serum proteomics and plasma fibulin-3 in differentiation of mesothelioma from asbestos-exposed controls and patients with other pleural diseases. Journal of Thoracic Oncology, 16(10), pp. 1705-1717. (doi: 10.1016/j.jtho.2021.05.018) (PMID:34116230) (PMCID:PMC8514249)

Mohan, S. et al. (2020) Profiling of circulating free DNA using targeted and genome-wide sequencing in patients with SCLC. Journal of Thoracic Oncology, 15(2), pp. 216-230. (doi: 10.1016/j.jtho.2019.10.007) (PMID:31629061) (PMCID:PMC7001105)

Chemi, F. et al. (2019) Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse. Nature Medicine, 25(10), pp. 1534-1539. (doi: 10.1038/s41591-019-0593-1) (PMID:31591595) (PMCID:PMC6986897)

Memon, D., Bi, J. and Miller, C. J. (2019) In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival. Scientific Reports, 9, 7372. (doi: 10.1038/s41598-019-43758-7) (PMID:31089191) (PMCID:PMC6517443)

Rothwell, D. G. et al. (2019) Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study. Nature Medicine, 25(5), pp. 738-743. (doi: 10.1038/s41591-019-0380-z) (PMID:31011204)

Parry, M. A. et al. (2019) Genomic evaluation of multiparametric magnetic resonance imaging-visible and -nonvisible lesions in clinically localised prostate cancer. European Urology Oncology, 2(1), pp. 1-11. (doi: 10.1016/j.euo.2018.08.005) (PMID:30929837) (PMCID:PMC6472613)

Lallo, A. et al. (2019) Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics. British Journal of Pharmacology, 176(3), pp. 436-450. (doi: 10.1111/bph.14542) (PMID:30427531) (PMCID:PMC6329630)

Kim, C. S., Mohan, S., Ayub, M., Rothwell, D. G., Dive, C., Brady, G. and Miller, C. (2018) In silico error correction improves cfDNA mutation calling. Bioinformatics, 35(14), pp. 2380-2385. (doi: 10.1093/bioinformatics/bty1004) (PMID:30520956) (PMCID:PMC6612818)

Lallo, A. et al. (2018) The combination of the PARP inhibitor Olaparib and the WEE1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer. Clinical Cancer Research, 24(20), pp. 5153-5164. (doi: 10.1158/1078-0432.CCR-17-2805) (PMID:29941481)

Torres-Ayuso, P. et al. (2018) Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin. npj Genomic Medicine, 3, 15. (doi: 10.1038/s41525-018-0055-6) (PMID:29951225) (PMCID:PMC6010465)

Hudson, A. M. et al. (2018) Truncation- and motif-based pan-cancer analysis reveals tumor-suppressing kinases. Science Signaling, 11(526), eaan6776. (doi: 10.1126/scisignal.aan6776) (PMID:29666306)

Bennett, L., Howell, M., Memon, D., Smowton, C., Zhou, C. and Miller, C. J. (2018) Mutation pattern analysis reveals polygenic mini-drivers associated with relapse after surgery in lung adenocarcinoma. Scientific Reports, 8, 14830. (doi: 10.1038/s41598-018-33276-3) (PMID:30287876) (PMCID:PMC6172282)

Chiu, A., Ayub, M., Dive, C., Brady, G., Miller, C. J. and Hancock, J. (2017) twoddpcr: an R/Bioconductor package and Shiny app for Droplet Digital PCR analysis. Bioinformatics, 33(17), pp. 2743-2745. (doi: 10.1093/bioinformatics/btx308) (PMID:28475662) (PMCID:PMC5860069)

Khandelwal, G. et al. (2017) Next-generation sequencing analysis and algorithms for PDX and CDX models. Molecular Cancer Research, 15(8), pp. 1012-1016. (doi: 10.1158/1541-7786.MCR-16-0431) (PMID:28442585)

Smowton, C., Balla, A., Antoniades, D., Miller, C. , Pallis, G., Dikaiakos, M. D. and Xing, W. (2017) A cost-effective approach to improving performance of big genomic data analyses in clouds. Future Generation Computer Systems, 67, pp. 368-381. (doi: 10.1016/j.future.2015.11.011)

Carter, L. et al. (2017) Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer. Nature Medicine, 23(1), pp. 114-119. (doi: 10.1038/nm.4239) (PMID:27869802)

Draper, J. E., Sroczynska, P., Leong, H. S., Fadlullah, M. Z. H., Miller, C. , Kouskoff, V. and Lacaud, G. (2017) Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors. Blood, 130(3), pp. 271-284. (doi: 10.1182/blood-2016-06-723635) (PMID:28490570) (PMCID:PMC5833261)

Williamson, S. C. et al. (2016) Vasculogenic mimicry in small cell lung cancer. Nature Communications, 7, 13322. (doi: 10.1038/ncomms13322) (PMID:27827359) (PMCID:PMC5105195)

Memon, D., Dawson, K., Smowton, C. S., Xing, W., Dive, C. and Miller, C. J. (2016) Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response. npj Genomic Medicine, 1, 16020. (doi: 10.1038/npjgenmed.2016.20) (PMID:28480052) (PMCID:PMC5417364)

Morrow, C.J. et al. (2016) Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study. Annals of Oncology, 27(6), pp. 1155-1160. (doi: 10.1093/annonc/mdw122) (PMID:27013395) (PMCID:PMC4880063)

Tape, C. J. et al. (2016) Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation. Cell, 165(4), pp. 910-920. (doi: 10.1016/j.cell.2016.03.029) (PMID:27087446) (PMCID:PMC4868820)

Rothwell, D. G. et al. (2016) Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample. Molecular Oncology, 10(4), pp. 566-574. (doi: 10.1016/j.molonc.2015.11.006) (PMID:26639657) (PMCID:PMC4834815)

Marusiak, A. A. et al. (2016) Recurrent MLK4 loss-of-function mutations suppress JNK signaling to promote colon tumorigenesis. Cancer Research, 76(3), pp. 724-735. (doi: 10.1158/0008-5472.can-15-0701-t) (PMID:26637668) (PMCID:PMC4740929)

Grimes, H. L., Draper, J. E., Sroczynska, P., Tsoulaki, O., Leong, H. S., Fadlullah, M. Z. H., Miller, C. , Kouskoff, V. and Lacaud, G. (2016) RUNX1B expression is highly heterogeneous and distinguishes megakaryocytic and erythroid lineage fate in adult mouse hematopoiesis. PLoS Genetics, 12(1), e1005814. (doi: 10.1371/journal.pgen.1005814) (PMID:26808730) (PMCID:PMC4726605)

Thambyrajah, R. et al. (2016) GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1. Nature Cell Biology, 18(1), pp. 21-32. (doi: 10.1038/ncb3276) (PMID:26619147)

Liu, J. et al. (2015) Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia. Oncotarget, 6(40), pp. 43048-43064. (doi: 10.18632/oncotarget.5528) (PMID:26474278) (PMCID:PMC4767490)

Antal, C. E. et al. (2015) Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor. Cell, 160(3), pp. 489-502. (doi: 10.1016/j.cell.2015.01.001) (PMID:25619690) (PMCID:PMC4313737)

Hudson, A. M., Wirth, C., Stephenson, N. L., Fawdar, S., Brognard, J. and Miller, C. J. (2015) Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges. Pharmacogenomics, 16(10), pp. 1149-1160. (doi: 10.2217/pgs.15.60) (PMID:26230733)

Rothwell, D. G. et al. (2014) Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells. BMC Genomics, 15, 1129. (doi: 10.1186/1471-2164-15-1129) (PMID:25519510) (PMCID:PMC4320548)

Hudson, A. M., Yates, T., Li, Y., Trotter, E. W., Fawdar, S., Chapman, P., Lorigan, P., Biankin, A. , Miller, C. and Brognard, J. (2014) Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery. Cancer Research, 74(22), pp. 6390-6396. (doi: 10.1158/0008-5472.CAN-14-1020) (PMID:25256751)

Lie-A-Ling, M., Marinopoulou, E., Li, Y., Patel, R., Stefanska, M., Bonifer, C., Miller, C., Kouskoff, V. and Lacaud, G. (2014) RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence. Blood, 124(11), e11-e20. (doi: 10.1182/blood-2014-04-572958) (PMID:25082880)

Aboussekhra, A. et al. (2014) Epithelial and stromal MicroRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation. PLoS ONE, 9(8), e105099. (doi: 10.1371/journal.pone.0105099) (PMID:25122196) (PMCID:PMC4133372)

Hodgkinson, C. L. et al. (2014) Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer. Nature Medicine, 20(8), pp. 897-903. (doi: 10.1038/nm.3600) (PMID:24880617)

Leong, H. S., Dawson, K., Wirth, C., Li, Y., Connolly, Y., Smith, D. L., Wilkinson, C. R. M. and Miller, C. J. (2014) A global non-coding RNA system modulates fission yeast protein levels in response to stress. Nature Communications, 5, 3947. (doi: 10.1038/ncomms4947) (PMID:24853205) (PMCID:PMC4050258)

Gires, O. et al. (2014) Investigation of radiosensitivity gene signatures in cancer cell lines. PLoS ONE, 9, e86329. (doi: 10.1371/journal.pone.0086329) (PMID:24466029) (PMCID:PMC3899227)

Conference or Workshop Item

Carter, L. R. et al. (2016) Abstract 3155: Investigating chemoresistance in small cell lung cancer through the molecular profiling of single circulating tumour cells. 107th Annual Meeting of the American Association for Cancer Research - Proceedings, New Orleans, LA. Philadelphia (PA), 16-20 Apr 2016. p. 3155. (doi: 10.1158/1538-7445.AM2016-3155)

Conference Proceedings

Smowton, C., Copil, G., Truong, H.-L., Miller, C. and Xing, W. (2015) Genome Analysis in a Dynamically Scaled Hybrid Cloud. In: 2015 IEEE 11th International Conference on e-Science, Munich, Germany, 31 Aug - 4 Sept 2015, pp. 391-400. ISBN 9781467393256 (doi: 10.1109/eScience.2015.17)

Smowton, C., Miller, C. , Xing, W., Balla, A., Antoniades, D., Pallis, G. and Dikaiakos, M. D. (2015) Analysing Cancer Genomics in the Elastic Cloud. In: 2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, Shenzhen, China, 4-7 May 2015, pp. 835-844. (doi: 10.1109/CCGrid.2015.176)

Xing, W., Jie, W. and Miller, C. (2015) SCAN: A Smart Application Platform for Empowering Parallelizations of Big Genomic Data Analysis in Clouds. In: 2015 44th International Conference on Parallel Processing, Beijing, China, 1-4 Sept 2015, pp. 290-299. ISBN 9781467375870 (doi: 10.1109/ICPP.2015.38)