Dr Elisa Alvarez-Curto

  • Research Associate (Institute of Molecular Cell & Systems Biology)

Research interests

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010
Number of items: 19.

2018

Marsango, S., Ward, R. J., Alvarez-Curto, E. and Milligan, G. (2018) Muscarinic receptor oligomerization. Neuropharmacology, 136(Part C), pp. 401-410. (doi: 10.1016/j.neuropharm.2017.11.023) (PMID:29146505) (PMCID:PMC6078712)

2017

Viskaitis, P. et al. (2017) Modulation of SF1 neuron activity coordinately regulates both feeding behaviour and associated emotional states. Cell Reports, 21(12), pp. 3559-3572. (doi: 10.1016/j.celrep.2017.11.089) (PMID:29262334) (PMCID:PMC5746599)

Milligan, G. , Alvarez-Curto, E. , Hudson, B. D. , Prihandoko, R. and Tobin, A. B. (2017) FFA4/GPR120: pharmacology and therapeutic opportunities. Trends in Pharmacological Sciences, 38(9), pp. 809-821. (doi: 10.1016/j.tips.2017.06.006) (PMID:28734639) (PMCID:PMC5582618)

Lopez-Gimenez, J., Alvarez-Curto, E. and Milligan, G. (2017) M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes. Cellular Signalling, 35, pp. 208-222. (doi: 10.1016/j.cellsig.2017.04.006) (PMID:28411124)

Watterson, K. R. et al. (2017) Probe-dependent negative allosteric modulators of the long-chain free fatty acid receptor FFA4. Molecular Pharmacology, 91(6), pp. 630-641. (doi: 10.1124/mol.116.107821) (PMID:28385906) (PMCID:PMC5438128)

2016

Alvarez-Curto, E. , Inoue, A., Jenkins, L. , Raihan, S. Z., Prihandoko, R., Tobin, A. B. and Milligan, G. (2016) Targeted elimination of G proteins and arrestins defines their specific contributions to both intensity and duration of G protein-coupled receptor signalling. Journal of Biological Chemistry, 291(53), pp. 27147-27159. (doi: 10.1074/jbc.M116.754887) (PMID:27852822) (PMCID:PMC5207144)

Alvarez-Curto, E. and Milligan, G. (2016) Metabolism meets immunity: the role of free fatty acid receptors in the immune system. Biochemical Pharmacology, 114, pp. 3-13. (doi: 10.1016/j.bcp.2016.03.017) (PMID:27002183)

Prihandoko, R., Alvarez-Curto, E. , Hudson, B. D. , Butcher, A. J., Ulven, T., Miller, A. M., Tobin, A. B. and Milligan, G. (2016) Distinct phosphorylation clusters determines the signalling outcome of the free fatty acid receptor FFA4/GPR120. Molecular Pharmacology, 89(5), pp. 505-520. (doi: 10.1124/mol.115.101949) (PMID:26873857)

2015

Milligan, G. , Alvarez-Curto, E. , Watterson, K.R., Ulven, T. and Hudson, B.D. (2015) Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4. British Journal of Pharmacology, 172(13), pp. 3254-3265. (doi: 10.1111/bph.12879) (PMID:25131623)

Aslanoglou, D., Alvarez-Curto, E. , Marsango, S. and Milligan, G. (2015) Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers. Journal of Biological Chemistry, 290(23), pp. 14785-14796. (doi: 10.1074/jbc.M115.649079) (PMID:25918156) (PMCID:PMC4505543)

Liste, M. J., Caltabiano, G., Ward, R. J., Alvarez-Curto, E. , Marsango, S. and Milligan, G. (2015) The molecular basis of oligomeric organization of the human m3 muscarinic acetylcholine receptor. Molecular Pharmacology, 87(6), pp. 936-953. (doi: 10.1124/mol.114.096925) (PMID:25769304)

Alvarez-Curto, E. and Milligan, G. (2015) Defining the functional equivalence of wild-type and chemically engineered G protein-coupled receptors. In: Thiel, G. (ed.) Designer Receptors Exclusively Activated by Designer Drugs. Series: Neuromethods (108). Springer New York, pp. 1-28. ISBN 9781493929436 (doi:10.1007/978-1-4939-2944-3_1)

2014

Butcher, A. J., Hudson, B. D. , Shimpukade, B., Alvarez-Curto, E. , Prihandoko, R., Ulven, T., Milligan, G. and Tobin, A. B. (2014) Concomitant action of structural elements and receptor phosphorylation determine arrestin-3 interaction with the free fatty acid receptor FFA4. Journal of Biological Chemistry, 289, pp. 18451-18465. (doi: 10.1074/jbc.M114.568816) (PMID:24817122) (PMCID:PMC4140278)

2013

Patowary, S., Alvarez-Curto, E. , Xu, T.-R., Holz, J.D., Oliver, J.A., Milligan, G. and Raicu, V. (2013) The muscarinic M3acetylcholine receptor exists as two differently sized complexes at the plasma membrane. Biochemical Journal, 452(2), pp. 303-312. (doi: 10.1042/BJ20121902)

2011

Alvarez-Curto, E. , Prihandoko, R., Tautermann, C. S., Zwier, J. M., Pediani, J. D. , Lohse, M. J., Hoffmann, C., Tobin, A. B. and Milligan, G. (2011) Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a Receptor Activated Solely by Synthetic Ligand (RASSL). Molecular Pharmacology, 80(6), pp. 1033-1046. (doi: 10.1124/mol.111.074674)

Ward, R.J., Alvarez-Curto, E. and Milligan, G. (2011) Using the Flp-In™ T-Rex™ System to Regulate GPCR Expression. Methods in Molecular Biology, 746, pp. 21-37. (doi: 10.1007/978-1-61779-126-0_2)

2010

Alvarez-Curto, E. , Pediani, J. D. and Milligan, G. (2010) Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors. Analytical and Bioanalytical Chemistry, 398(1), pp. 167-180. (doi: 10.1007/s00216-010-3823-4)

Alvarez-Curto, E., Ward, R. J., Pediani, J. D. and Milligan, G. (2010) Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogenous time-resolved FRET. Journal of Biological Chemistry, 285(30), pp. 23318-23330. (doi: 10.1074/jbc.M110.122184)

Jenkins, L. , Alvarez-Curto, E. , Campbell, K., De Munnik, S., Canals Buj, M., Schlyer, S. and Milligan, G. (2010) Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2. British Journal of Pharmacology, 162(3), pp. 733-748. (doi: 10.1111/j.1476-5381.2010.01082.x)

This list was generated on Wed Jul 8 23:01:54 2020 BST.
Number of items: 19.

Articles

Marsango, S., Ward, R. J., Alvarez-Curto, E. and Milligan, G. (2018) Muscarinic receptor oligomerization. Neuropharmacology, 136(Part C), pp. 401-410. (doi: 10.1016/j.neuropharm.2017.11.023) (PMID:29146505) (PMCID:PMC6078712)

Viskaitis, P. et al. (2017) Modulation of SF1 neuron activity coordinately regulates both feeding behaviour and associated emotional states. Cell Reports, 21(12), pp. 3559-3572. (doi: 10.1016/j.celrep.2017.11.089) (PMID:29262334) (PMCID:PMC5746599)

Milligan, G. , Alvarez-Curto, E. , Hudson, B. D. , Prihandoko, R. and Tobin, A. B. (2017) FFA4/GPR120: pharmacology and therapeutic opportunities. Trends in Pharmacological Sciences, 38(9), pp. 809-821. (doi: 10.1016/j.tips.2017.06.006) (PMID:28734639) (PMCID:PMC5582618)

Lopez-Gimenez, J., Alvarez-Curto, E. and Milligan, G. (2017) M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes. Cellular Signalling, 35, pp. 208-222. (doi: 10.1016/j.cellsig.2017.04.006) (PMID:28411124)

Watterson, K. R. et al. (2017) Probe-dependent negative allosteric modulators of the long-chain free fatty acid receptor FFA4. Molecular Pharmacology, 91(6), pp. 630-641. (doi: 10.1124/mol.116.107821) (PMID:28385906) (PMCID:PMC5438128)

Alvarez-Curto, E. , Inoue, A., Jenkins, L. , Raihan, S. Z., Prihandoko, R., Tobin, A. B. and Milligan, G. (2016) Targeted elimination of G proteins and arrestins defines their specific contributions to both intensity and duration of G protein-coupled receptor signalling. Journal of Biological Chemistry, 291(53), pp. 27147-27159. (doi: 10.1074/jbc.M116.754887) (PMID:27852822) (PMCID:PMC5207144)

Alvarez-Curto, E. and Milligan, G. (2016) Metabolism meets immunity: the role of free fatty acid receptors in the immune system. Biochemical Pharmacology, 114, pp. 3-13. (doi: 10.1016/j.bcp.2016.03.017) (PMID:27002183)

Prihandoko, R., Alvarez-Curto, E. , Hudson, B. D. , Butcher, A. J., Ulven, T., Miller, A. M., Tobin, A. B. and Milligan, G. (2016) Distinct phosphorylation clusters determines the signalling outcome of the free fatty acid receptor FFA4/GPR120. Molecular Pharmacology, 89(5), pp. 505-520. (doi: 10.1124/mol.115.101949) (PMID:26873857)

Milligan, G. , Alvarez-Curto, E. , Watterson, K.R., Ulven, T. and Hudson, B.D. (2015) Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4. British Journal of Pharmacology, 172(13), pp. 3254-3265. (doi: 10.1111/bph.12879) (PMID:25131623)

Aslanoglou, D., Alvarez-Curto, E. , Marsango, S. and Milligan, G. (2015) Distinct agonist regulation of muscarinic acetylcholine M2-M3 heteromers and their corresponding homomers. Journal of Biological Chemistry, 290(23), pp. 14785-14796. (doi: 10.1074/jbc.M115.649079) (PMID:25918156) (PMCID:PMC4505543)

Liste, M. J., Caltabiano, G., Ward, R. J., Alvarez-Curto, E. , Marsango, S. and Milligan, G. (2015) The molecular basis of oligomeric organization of the human m3 muscarinic acetylcholine receptor. Molecular Pharmacology, 87(6), pp. 936-953. (doi: 10.1124/mol.114.096925) (PMID:25769304)

Butcher, A. J., Hudson, B. D. , Shimpukade, B., Alvarez-Curto, E. , Prihandoko, R., Ulven, T., Milligan, G. and Tobin, A. B. (2014) Concomitant action of structural elements and receptor phosphorylation determine arrestin-3 interaction with the free fatty acid receptor FFA4. Journal of Biological Chemistry, 289, pp. 18451-18465. (doi: 10.1074/jbc.M114.568816) (PMID:24817122) (PMCID:PMC4140278)

Patowary, S., Alvarez-Curto, E. , Xu, T.-R., Holz, J.D., Oliver, J.A., Milligan, G. and Raicu, V. (2013) The muscarinic M3acetylcholine receptor exists as two differently sized complexes at the plasma membrane. Biochemical Journal, 452(2), pp. 303-312. (doi: 10.1042/BJ20121902)

Alvarez-Curto, E. , Prihandoko, R., Tautermann, C. S., Zwier, J. M., Pediani, J. D. , Lohse, M. J., Hoffmann, C., Tobin, A. B. and Milligan, G. (2011) Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a Receptor Activated Solely by Synthetic Ligand (RASSL). Molecular Pharmacology, 80(6), pp. 1033-1046. (doi: 10.1124/mol.111.074674)

Ward, R.J., Alvarez-Curto, E. and Milligan, G. (2011) Using the Flp-In™ T-Rex™ System to Regulate GPCR Expression. Methods in Molecular Biology, 746, pp. 21-37. (doi: 10.1007/978-1-61779-126-0_2)

Alvarez-Curto, E. , Pediani, J. D. and Milligan, G. (2010) Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors. Analytical and Bioanalytical Chemistry, 398(1), pp. 167-180. (doi: 10.1007/s00216-010-3823-4)

Alvarez-Curto, E., Ward, R. J., Pediani, J. D. and Milligan, G. (2010) Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogenous time-resolved FRET. Journal of Biological Chemistry, 285(30), pp. 23318-23330. (doi: 10.1074/jbc.M110.122184)

Jenkins, L. , Alvarez-Curto, E. , Campbell, K., De Munnik, S., Canals Buj, M., Schlyer, S. and Milligan, G. (2010) Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2. British Journal of Pharmacology, 162(3), pp. 733-748. (doi: 10.1111/j.1476-5381.2010.01082.x)

Book Sections

Alvarez-Curto, E. and Milligan, G. (2015) Defining the functional equivalence of wild-type and chemically engineered G protein-coupled receptors. In: Thiel, G. (ed.) Designer Receptors Exclusively Activated by Designer Drugs. Series: Neuromethods (108). Springer New York, pp. 1-28. ISBN 9781493929436 (doi:10.1007/978-1-4939-2944-3_1)

This list was generated on Wed Jul 8 23:01:54 2020 BST.