MVLS Structural Biology and Biophysical Characterisation Facility

MVLS Structural Biology and Biophysical Characterisation Facility

Examples of some of the structures that we have determined in Glasgow

The MVLS Structural Biology and Biophysical Characterisation Facility is dedicated to research into macromolecular structure and characterisation. The facility offers a wide range of biophysical techniques such as, analytical ultracentrifugation (AUC), circular dichroism (CD), Fourier transform infra red spectroscopuy (FTIR), isothermal calorimetry (ITC), nuclear magnetic resonance spectroscopy (NMR), X-ray crystallography and UV-VIS spectroscopy to support researchers in the determination and analysis of molecular structure, structural integrity, stability, and interactions with other macromolecules, ligands, and membranes.

The work in the facility is underpinned by a wide range of state of the art biophysical equipment, including two analytical ultracentrifuges, a 600MHz NMR spectrometer and cryoprobe and a fully equipped X-ray crystallography suite including robots for initial screening of crystallisation conditions.

The following services are available for use: