New publication from the Milligan Lab

Dr Laura Jenkins and Prof. Graeme Milligan's have recently published a paper: 'Discovery of 9-Cyclopropylethynyl-2-(( S)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1- a]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial’. 

It came from a very productive and close collaboration with the pharmaceutical company Galapagos NV. 

Please view the Paper here.

Journal of Medicinal Chemistry (2020) 63(22):13526-13545 

First published: 4 December 2020

<< Archive