7-Oct-2016 Paul Johnson “Genetics in geographically structured populations: defining, estimating and interpreting Fst (or What the Fst is going on?)"

Issued: Thu, 11 Feb 2016 21:35:00 GMT

Friday 7th October 12-1 pm
Graham Kerr Building, Library

Our very own Dr. Paul Johnson will be giving a talk, entitled Genetics in geographically structured populations: defining, estimating and interpreting Fst (or What the Fst is going on?)on the Friday the 7th of October at 12 pm in the GK library

 

Recommended reading:

Holsinger, K. E., and B. S. Weir. 2009. Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nature reviews. Genetics 10:639–650.

"Wright’s F-statistics, and especially FST, provide important insights into the evolutionary processes that influence the structure of genetic variation within and among populations, and they are among the most widely used descriptive statistics in population and evolutionary genetics. Estimates of FST can identify regions of the genome that have been the target of selection, and comparisons of FST from different parts of the genome can provide insights into the demographic history of populations. For these reasons and others, FST has a central role in population and evolutionary genetics and has wide applications in fields that range from disease association mapping to forensic science. This Review clarifies how FST is defined, how it should be estimated, how it is related to similar statistics and how estimates of FST should be interpreted."