Alisha Aman

 

School of Cardiovascular and Metabolic Health | School of Health and Wellbeing

College of Medical, Veterinary, and Life Sciences

University of Glasgow

BHF Glasgow Cardiovascular Research Centre

126 University Place

Glasgow, G12 8TA

Research title: Phenomic and pharmacogenomic dissection of blood pressure GW

Research Summary

Investigating the association between cardiovascular disorders and mental health with GWAS and quantitative trait loci data by using Mendelian Randomization

Publications

List by: Type | Date

Jump to: 2022 | 2021 | 2020 | 2019 | 2018 | 2017
Number of items: 10.

2022

Aman, A. , Slob, E. A.W., Ward, J. , Cullen, B. , Graham, N., Lyall, D. M. , Sattar, N. and Strawbridge, R. J. (2022) Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization. PLoS ONE, 17(12), e0279381. (doi: 10.1371/journal.pone.0279381) (PMID:36580462) (PMCID:PMC9799310)

Hay, R., Cullen, B. , Graham, N., Lyall, D. M. , Aman, A. , Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2022) Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank. European Journal of Human Genetics, 30(12), pp. 1380-1390. (doi: 10.1038/s41431-022-01107-9) (PMID:35501368) (PMCID:PMC9712543)

2021

McCallum, L., Brooksbank, K., McConnachie, A. , Aman, A. , Lip, S., Dawson, J. , MacIntyre, I. M., MacDonald, T. M., Webb, D. J. and Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD). American Journal of Hypertension, 34(1), pp. 92-99. (doi: 10.1093/ajh/hpaa166) (PMID:33084880) (PMCID:PMC7891239)

2020

Ford, T. J. et al. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41(34), pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915) (PMID:31972008) (PMCID:PMC7557475)

2019

Menni, C. et al. (2019) Metabolomic profiling identifies novel associations with electrolyte and acid-base homeostatic patterns. Scientific Reports, 9, 15088. (doi: 10.1038/s41598-019-51492-3) (PMID:31636301) (PMCID:PMC6803625)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genetics of hypertension and heart failure. In: Dorobantu, M., Mancia, G., Grassi, G. and Voicu, V. (eds.) Hypertension and Heart Failure. Series: Updates in hypertension and cardiovascular protection. Springer International Publishing, pp. 15-29. ISBN 9783319933191

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_16)

2018

Graham, L. A., Aman, A. , Campbell, D. D. , Augley, J., Graham, D. , McBride, M. W. , Fraser, N. J., Ferreri, N. R., Dominiczak, A. F. and Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

2017

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2017) Genomics of hypertension. Pharmacological Research, 121, pp. 219-229. (doi: 10.1016/j.phrs.2017.04.031) (PMID:28495658)

This list was generated on Tue Feb 7 23:11:34 2023 GMT.
Number of items: 10.

Articles

Aman, A. , Slob, E. A.W., Ward, J. , Cullen, B. , Graham, N., Lyall, D. M. , Sattar, N. and Strawbridge, R. J. (2022) Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization. PLoS ONE, 17(12), e0279381. (doi: 10.1371/journal.pone.0279381) (PMID:36580462) (PMCID:PMC9799310)

Hay, R., Cullen, B. , Graham, N., Lyall, D. M. , Aman, A. , Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2022) Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank. European Journal of Human Genetics, 30(12), pp. 1380-1390. (doi: 10.1038/s41431-022-01107-9) (PMID:35501368) (PMCID:PMC9712543)

McCallum, L., Brooksbank, K., McConnachie, A. , Aman, A. , Lip, S., Dawson, J. , MacIntyre, I. M., MacDonald, T. M., Webb, D. J. and Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD). American Journal of Hypertension, 34(1), pp. 92-99. (doi: 10.1093/ajh/hpaa166) (PMID:33084880) (PMCID:PMC7891239)

Ford, T. J. et al. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41(34), pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915) (PMID:31972008) (PMCID:PMC7557475)

Menni, C. et al. (2019) Metabolomic profiling identifies novel associations with electrolyte and acid-base homeostatic patterns. Scientific Reports, 9, 15088. (doi: 10.1038/s41598-019-51492-3) (PMID:31636301) (PMCID:PMC6803625)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

Graham, L. A., Aman, A. , Campbell, D. D. , Augley, J., Graham, D. , McBride, M. W. , Fraser, N. J., Ferreri, N. R., Dominiczak, A. F. and Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2017) Genomics of hypertension. Pharmacological Research, 121, pp. 219-229. (doi: 10.1016/j.phrs.2017.04.031) (PMID:28495658)

Book Sections

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genetics of hypertension and heart failure. In: Dorobantu, M., Mancia, G., Grassi, G. and Voicu, V. (eds.) Hypertension and Heart Failure. Series: Updates in hypertension and cardiovascular protection. Springer International Publishing, pp. 15-29. ISBN 9783319933191

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_16)

This list was generated on Tue Feb 7 23:11:34 2023 GMT.

Conference

 

  1. Canadian Vascular Network Summer School, Montreal, Canada (August 2019)
  2. Brainstorm meeting for the Global Challenge Research Fund application at New Delhi (March 2018) and Sri Lanka (December 2017) in collaboration with University of Glasgow MVLS and Business School, Bangladesh, Indonesia, India, Nepal, and Malaysia.
  3. Oral presentation - European Society of Hypertension (ESH) annual meeting, Milan (June 2017)
  4. Poster Presentation -Indian Genetics Congress, Chennai (February 2015)

Teaching

Genomics laboratory for undergraduate (BSc) in Genetics degree (2019-)

Bioinformatics laboratory (population genetics data analyses) MSc in Bioinformatics degree (2022-)