UofG undergrad iGEM team wins award

UofG undergrad iGEM team wins award

Issued: Fri, 17 Nov 2017 11:43:00 GMT

Last weekend, more than six thousand university and high school students from around the world competed in Boston, USA at the iGEM 2017 Giant Jamboree, writes Dr Julien Reboud,  Lecturer in Engineering. 

This is the world's premier synthetic biology competition, showcasing innovative and responsible biologically-engineered solutions to real-world challenges.

The Glasgow iGEM undergraduate team, assembled seven molecular biologists, two biomedical engineering students, and one student from social science. They worked for 12 weeks over the summer to deliver a synthetic biology project, which they presented to more than 300 other iGEM teams, and to the judges, who awarded their project the best project prize in the category ‘Food and Nutrition’. 

iGEM team 2017

The Glasgow project was also shortlisted for Best Innovation in Measurement, Best Wiki, and Best Applied Design and Best Part Collection. Full results here.

The Glasgow project, ‘CampyLOCATOR’, was aimed at developing a genetically engineered biosensor to detect the presence of the bacterium Campylobacter jejuni, which is one of the most prevalent causes of food poisoning in the UK. The team has used technologies such as microfluidics and rapid prototyping to produce a biosensor that uses modified non-pathogenic E. coli bacteria to give a visual indication of the presence of Campylobacter.

The bulk of the team’s molecular biology work centred on producing a genetic circuit for E. coli to sense the presence of a rare sugar molecule (xylulose) on the surface of Campylobacter  cells. The team utilised novel molecular biology techniques, and in keeping with the iGEM tradition, they documented these fully on their wiki for use by future iGEM teams and the wider community.

Campylobacter causes more cases of food poisoning in the UK than E. coli, Listeria, and Salmonella put together. It can be spread easily, often from raw or undercooked chicken, or from contamination due to washing raw chicken, and just a few bacteria can cause illness.

‌‌The team also considered the social and ethical implications of their work. They engaged in activities to raise awareness on the nature of foodborne related diseases and how to prevent them. To build their activities, they established a dialogue with the Food Standards Agency, who estimated from research that most people don’t know about or don’t follow advice about handling and preparing raw chicken.

Image of the iGEM award and mascotThey delivered a two-day workshop at the Glasgow Science Centre and participated in the Explorathon at the Riverside Museum, using their mascot Henrietta (see photo) to interact with the public in a fun and engaging way. The project resulted in a policy brief that the students plan to publicise widely to raise awareness of the potential impact of Brexit on food safety.    

The team was supported by Dr Sean Colloms, Dr Julien Reboud, as well as PhD students James Provan, Jumai Abioye, and Katy Baker. For the first time in five years of participation, the Glasgow team was awarded the top prize for their project category in Food and Nutrition’, one of only 11 prizes, for which 313 teams were competing. This great result and thair nominations for other, highly competetive prizes are a testament to the hard work and dedication they put into their work over the summer.

The project was supported by the Wellcome Trust, BBSRC, the IMechE, Society for Experimental Biology and the Microbiology Society. 

iGem team receiving award 2017