IHW researchers find genetic link between circadian rhythms and mood disorders

Issued: Fri, 14 Sep 2018 11:38:00 BST

University of Glasgow scientists have identified a possible genetic link between circadian disruption and mood disorders. In the largest ever study of circadian rest-activity cycles in humans, researchers from the Institute of Health and Wellbeing identified two areas of the human genome that may contain genetic variants that increase risk of disruption to rest-activity cycles.

Professor Daniel Smith, Professor of Psychiatry, Institute of Health and Wellbeing, commented: “These new findings extend our understanding of the complex genetic architecture of rest-activity cycles and how these might relate to mood instability, neuroticism, depression and bipolar disorder. Ultimately, our goal is to use this information to develop and efficiently target or stratify new and improved treatment options”.