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Number of items: 23.

2019

Bilsland, A. E. , Liu, Y., Turnbull, A., Sumpton, D., Stevenson, K., Cairney, C. J., Boyd, S. M., Roffey, J., Jenkinson, D. and Keith, W. N. (2019) A novel pyrazolopyrimidine ligand of human PGK1 and stress sensor DJ1 modulates the shelterin complex and telomere length regulation. Neoplasia, 21(9), pp. 893-907. (doi: 10.1016/j.neo.2019.07.008) (PMID:31401411) (PMCID:PMC6700475)

2017

Cairney, C. J. et al. (2017) A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PLoS Genetics, 13(8), e1006942. (doi: 10.1371/journal.pgen.1006942) (PMID:28806777) (PMCID:PMC5570495)

Wilson, G. J. , Hewit, K. D., Pallas, K. J., Cairney, C. J., Lee, K. M., Hansell, C. A., Stein, T. and Graham, G. J. (2017) Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland. Development, 144, pp. 74-82. (doi: 10.1242/dev.139733) (PMID:27888192) (PMCID:PMC5278629)

2016

Ibrahim, A. M., Cairney, C., Morris, J. S. and Stein, T. (2016) RNA profiling of non-cultured fibroblasts isolated from pubertal mouse mammary gland sections. In: Martin, F., Stein, T. and Howlin, J. (eds.) Mammary Gland Development. Series: Methods in Molecular Biology (1501). Humana Press: New York, pp. 149-164. ISBN 9781493964734 (doi: 10.1007/978-1-4939-6475-8_6)

2015

Sadaie, M., Dillon, C., Narita, M., Young, A.R.J., Cairney, C., Godwin, L.S., Torrance, C.J., Bennett, D.C., Keith, N. and Narita, M. (2015) Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Molecular Biology of the Cell, 26(17), pp. 2971-2985. (doi: 10.1091/mbc.E15-01-0003) (PMID:26133385) (PMCID:PMC4551313)

Bilsland, A. E. et al. (2015) Identification of a selective G1-phase benzimidazolone inhibitor by a senescence-targeted virtual screen using artificial neural networks. Neoplasia, 17(9), pp. 704-715. (doi: 10.1016/j.neo.2015.08.009) (PMID:26476078) (PMCID:PMC4611071)

Iglesias, J. M. et al. (2015) Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium. PLoS ONE, 10(3), e0119718. (doi: 10.1371/journal.pone.0119718) (PMID:25803307) (PMCID:PMC4372349)

2014

Bilsland, A. E. , Stevenson, K., Liu, Y., Hoare, S., Cairney, C. J., Roffey, J. and Keith, W. N. (2014) Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms. PLoS Computational Biology, 10(2), e1003448. (doi: 10.1371/journal.pcbi.1003448) (PMID:24550717) (PMCID:PMC3923661)

Godwin, L. S., Castle, J. T., Kohli, J. S., Goff, P. S., Cairney, C. J., Keith, W. N. , Sviderskaya, E. V. and Bennett, D. C. (2014) Isolation, culture, and transfection of melanocytes. In: Current Protocols in Cell Biology. Wiley-Blackwell, 1.8.1-1.8.20. ISBN 9780471143031 (doi: 10.1002/0471143030.cb0108s63)

2012

Mohanty, S.T. et al. (2012) A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice. Stem Cells, 30(6), pp. 1134-43. (doi: 10.1002/stem.1065)

Cairney, C.J., Bilsland, A.E. , Evans, T.R.J. , Roffey, J., Bennett, D.C., Narita, M., Torrance, C. and Keith, W.N. (2012) Cancer cell senescence: a new frontier in drug development. Drug Discovery Today, 17(5-6), pp. 269-276. (doi: 10.1016/j.drudis.2012.01.019)

Keith, W.N. , Lafferty-Whyte, K., Cairney, C.J., Zaffaroni, N. and Bilsland, A. (2012) Response to ‘Validating a gene expression signature proposed to differentiate liposarcomas that use different telomere maintenance mechanism. Oncogene, 31(2), pp. 267-268. (doi: 10.1038/onc.2011.374)

2011

Bilsland, A.E. , Cairney, C.J. and Keith, W.N. (2011) Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives. Journal of Cellular and Molecular Medicine, 15(2), pp. 179-186. (doi: 10.1111/j.1582-4934.2010.01253.x)

2010

Lafferty-Whyte, K., Bilsland, A. , Hoare, S.F., Burns, S., Zaffaroni, N., Cairney, C.J. and Keith, W.N. (2010) TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression. Neoplasia, 12(5), pp. 405-414.

Lafferty-Whyte, K. et al. (2010) Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma. BMC Genomics, 11(1), p. 532. (doi: 10.1186/1471-2164-11-532)

2009

Lafferty-Whyte, K., Cairney, C.J., Will, M.B., Serakinci, N., Daidone, M.G., Zaffaroni, N., Bilsland, A.E. and Keith, W.N. (2009) A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT. Oncogene, 28(43), pp. 3765-3774. (doi: 10.1038/onc.2009.238)

Sitaram, R.T., Cairney, C.J., Grabowski, P., Keith, W.N. , Hallberg, B., Ljungberg, B. and Roos, G. (2009) The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma. International Journal of Cancer, 125(4), pp. 783-790. (doi: 10.1002/ijc.24335)

Bilsland, A.E., Hoare, S.F., Stevenson, K.H., Plumb, J.A., Gomez-Roman, N. , Cairney, C.J., Burns, S., Lafferty-Whyte, K., Hammonds, T. and Keith, W.N. (2009) Dynamic telomerase gene suppression via network effects of GSK3 inhibition. PLoS ONE, 4(7), e6459. (doi: 10.1371/journal.pone.0006459)

Cairney, C.J., Sanguinetti, G., Ranghini, E., Chantry, A.D., Nostro, M.C., Bhattacharyya, A., Svendsen, C.N., Keith, W.N. and Bellantuono, I. (2009) A systems biology approach to Down syndrome: Identification of Notch/Wnt dysregulation in a model of stem cells aging. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1792(4), pp. 353-363. (doi: 10.1016/j.bbadis.2009.01.015)

Lafferty-Whyte, K., Cairney, C.J., Jamieson, N., Oien, K.A. and Keith, W.N. (2009) Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1792(4), pp. 341-352. (doi: 10.1016/j.bbadis.2009.02.003)

2008

Cairney, C., Hoare, S., Daidone, M., Zaffaroni, N. and Keith, W. (2008) High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma. British Journal of Cancer, 98(8), pp. 1467-1474. (doi: 10.1038/sj.bjc.6604328)

Cairney, C. and Keith, W. (2008) Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity. Biochimie, 90(1), pp. 13-23. (doi: 10.1016/j.biochi.2007.07.025)

2007

Serakinci, N., Christensen, R., Graakjaer, J., Cairney, C.J., Keith, W.N. , Alsner, J., Saretzki, G. and Koluraa, S. (2007) Ectopically hTERT expressing adult human mesenchymal stem cells are less radiosensitive than their telomerase negative counterpart. Experimental Cell Research, 313, pp. 1056-1067. (doi: 10.1016/j.yexcr.2007.01.002)

This list was generated on Mon Mar 25 16:02:15 2024 GMT.