2024

O'Reilly, E. L. et al. (2024) Biomarker and proteome analysis of milk from dairy cows with clinical mastitis: determining the effect of different bacterial pathogens on the response to infection. Research in Veterinary Science, 172, 105240. (doi: 10.1016/j.rvsc.2024.105240) (PMID:38608347)

2023

Huang, Y., Jonsson, N. N. , McLaughlin, M. , Burchmore, R. , Johnson, P. C.D. , Jones, R. , McGill, S., Brady, N., Weidt, S. and Eckersall, D. (2023) Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer. Journal of Proteomics, 285, 104941. (doi: 10.1016/j.jprot.2023.104941) (PMID:37285906)

Peinado-Izaguerri, J. , Zarzuela, E., McLaughlin, M. , Small, A. C., Riva, F., McKeegan, D. E.F. , Bain, M. , Muñoz, J., Bhide, M. and Preston, T. (2023) A novel dynamic proteomics approach for the measurement of broiler chicken protein fractional synthesis rate. Rapid Communications in Mass Spectrometry, 37(10), e9497. (doi: 10.1002/rcm.9497) (PMID:36851885)

Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)

Nguyen, T. X., Agazzo, A., McGill, S., Weidt, S., Han, Q. H., Gelemanović, A., McLaughlin, M. , Savoini, G., Eckersall, P. D. and Burchmore, R. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes. Journal of Proteomics, 270, 104739. (doi: 10.1016/j.jprot.2022.104739) (PMID:36174954)

2022

Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)

2021

McGonigal, R. , Barrie, J. A., Yao, D., Black, L. E. , McLaughlin, M. and Willison, H. J. (2021) Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of Neurochemistry, 158(2), pp. 217-232. (doi: 10.1111/jnc.15365) (PMID:33864399)

Almeida, A. M. et al. (2021) Domestic animal proteomics in the 21st century: A global retrospective and viewpoint analysis. Journal of Proteomics, 241, 104220. (doi: 10.1016/j.jprot.2021.104220) (PMID:33838350)

Baka, R. et al. (2021) Quantitative proteomics of cerebrospinal fluid using tandem mass tags in dogs with recurrent epileptic seizures. Journal of Proteomics, 231, 103997. (doi: 10.1016/j.jprot.2020.103997) (PMID:33011347)

Horvatić, A. et al. (2021) Multi-omics approach to elucidate cerebrospinal fluid changes in dogs with intervertebral disc herniation. International Journal of Molecular Sciences, 22(21), 11678. (doi: 10.3390/ijms222111678)

2020

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

McNaught, K. A., Morris, J. S. and McLaughlin, M. (2020) Preliminary assessment of serum clusterin as a potential biomarker for canine lymphoma. Veterinary and Comparative Oncology, 18(3), pp. 292-302. (doi: 10.1111/vco.12550) (PMID:31654603)

Gruenenfelder, F. I. et al. (2020) Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease. Brain, 143(5), pp. 1383-1399. (doi: 10.1093/brain/awaa080) (PMID:32419025) (PMCID:PMC7462093)

2019

Qi, Y., Montague, P., Loney, C. , Campbell, C., Shafie, I., Anderson, T. and McLaughlin, M. (2019) In vitro evidence consistent with an interaction between wild type and a mutant SOD 1 protein associated with canine degenerative myelopathy. European Journal of Neuroscience, 50(12), pp. 3896-3905. (doi: 10.1111/ejn.14526) (PMID:31336405)

Hough, D. , Robinson, J.E. , Bellingham, M. , Fleming, L.M., McLaughlin, M. , Jama, K., Haraldsen, I.R.H., Solbakk, A.K. and Evans, N.P. (2019) Peripubertal GnRH and testosterone co-treatment leads to increased familiarity preferences in male sheep. Psychoneuroendocrinology, 108, pp. 70-77. (doi: 10.1016/j.psyneuen.2019.06.008) (PMID:31229635) (PMCID:PMC6712355)

Gutierrez-Quintana, R. , McLaughlin, M. , Grau Roma, L., Hammond, G., Gray, A. and Lowrie, M. (2019) Spongiform leucoencephalomyelopathy in border terriers: clinical, electrophysiological and imaging features. Veterinary Record, 185, 375. (doi: 10.1136/vr.105240) (PMID:31346136)

Bijland, S. et al. (2019) An in vitro model for studying CNS white matter: functional properties and experimental approaches. F1000Research, 8, 117. (doi: 10.12688/f1000research.16802.1) (PMID:31069065) (PMCID:PMC6489523)

McGonigal, R. , Barrie, J.A., Yao, D., McLaughlin, M. , Cunningham, M.E. , Rowan, E.G. and Willison, H.J. (2019) Glial sulfatides and neuronal complex gangliosides are functionally interdependent in maintaining myelinating axon integrity. Journal of Neuroscience, 39(1), pp. 63-77. (doi: 10.1523/JNEUROSCI.2095-18.2018) (PMID:30446529) (PMCID:PMC6325269)

2018

Wyse, C.A., Zhang, X., McLaughlin, M. , Biello, S.M. , Hough, D., Bellingham, M. , Curtis, A.M., Robinson, J.E. and Evans, N.P. (2018) Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: effects of photoperiod, environment and weaning. Physiology and Behavior, 194, pp. 362-370. (doi: 10.1016/j.physbeh.2018.06.001) (PMID:29894760)

2017

Hough, D. , Bellingham, M. , Haraldsen, J.R., McLaughlin, M. , Robinson, J.E. , Solbakk, A.K. and Evans, N.P. (2017) A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep. Psychoneuroendocrinology, 77, pp. 1-8. (doi: 10.1016/j.psyneuen.2016.11.029) (PMID:27987429) (PMCID:PMC5333793)

Hough, D. , Bellingham, M. , Haraldsen, I.R.H., McLaughlin, M. , Rennie, M., Robinson, J.E. , Solbakk, A.K. and Evans, N.P. (2017) Spatial memory is impaired by peripubertal GnRH agonist treatment and testosterone replacement in sheep. Psychoneuroendocrinology, 75, pp. 173-182. (doi: 10.1016/j.psyneuen.2016.10.016) (PMID:27837697) (PMCID:PMC5140006)

2016

Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)

2015

Braceland, M., McLoughlin, M.F., Tinsley, J., Wallace, C., Cockerill, D., McLaughlin, M. and Eckersall, P.D. (2015) Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. Journal of Fish Diseases, 28(9), pp. 821-831. (doi: 10.1111/jfd.12296) (PMID:25168106)

Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Wilson, D., Herzyk, P. , Eckersall, P. and Zadoks, R. (2015) Using label-free quantitative proteomics and untargeted metabolomics to study bovine mastitis. In: Science with Impact – BSAS Annual Conference 2015, University of Chester, UK, 14-15 Apr 2015, p. 70. (doi: 10.1017/S2040470015000023)

2014

Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Herzyk, P. , Eckersall, P. and Zadoks, R. (2014) Integrative label-free quantitative proteomics study in mastitis. In: Final Showcase Meeting of Farm Animal Proteomics, Milan, Italy, 17-18 Nov 2014, pp. 98-101. ISBN 9789086868100 (doi: 10.3920/978-90-8686-810-0)

Shafie, I. N.F., McLaughlin, M. , Burchmore, R. , Lim, M. A. A., Montague, P., Johnston, P. E.J. , Penderis, J. and Anderson, T. J. (2014) The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog. Cell Stress and Chaperones, 19(3), pp. 311-320. (doi: 10.1007/s12192-013-0457-4)

Almeida, A.M. et al. (2014) Animal board invited review: advances in proteomics for animal and food sciences. Animal, 9(1), pp. 1-17. (doi: 10.1017/S1751731114002602) (PMID:25359324) (PMCID:PMC4301196)

Albalat, A., Husi, H., Siwy, J., Nally, J. E., McLaughlin, M. , Eckersall, P. D. and Mullen, W. (2014) Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals. Current Protein and Peptide Science, 15(1), pp. 23-35. (doi: 10.2174/1389203715666140221123920) (PMID:24555889)

Ghazali, M., Koh-Tan, H. H., McLaughlin, M. , Montague, P., Jonsson, N. N. and Eckersall, P. (2014) Alkaline phosphatase in nasal secretion of cattle: biochemical and molecular characterisation. BMC Veterinary Research, 10(1), 204. (doi: 10.1186/s12917-014-0204-9) (PMID:25927913) (PMCID:PMC4173004)

McQueen, J., Reimer, M.M., Holland, P.R., Manso, Y., McLaughlin, M. , Fowler, J.H. and Horsburgh, K. (2014) Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion. PLoS ONE, 9(2), e87227. (doi: 10.1371/journal.pone.0087227) (PMID:24498301) (PMCID:PMC3911923)

2013

Shafie, I.N.F., Anderson, T.J. , Penderis, J., Eckersall, P.D. and McLaughlin, M. (2013) A protocol for the management of canine cerebrospinal fluid for the proteomic assessment of putative biomarkers. Veterinary Journal, 197(3), pp. 836-841. (doi: 10.1016/j.tvjl.2013.05.039)

2011

Eckersall, P. D. and McLaughlin, M. (2011) Proteomics in animal health and disease. In: Eckersall, P. D. and Whitfield, P. D. (eds.) Methods in Animal Proteomics. Wiley-Blackwell, pp. 243-318. ISBN 9780813817910 (doi: 10.1002/9780470960660.ch10)

2010

Karim, S., Barrie, J., McCulloch, M., Montague, P., Edgar, J.M. , Iden, D.L., Anderson, T.J. , Nave, K.-A., Griffiths, I.R. and McLaughlin, M. (2010) PLP/DM20 expression and turnover in a transgenic mouse model of pelizaeus-merzbacher disease. Glia, 58(14), pp. 1727-1738. (doi: 10.1002/glia.21043)

Barrie, J.A., Montague, P., Karim, S.A., Kirkham, D., Nave, K.-A., Anderson, T.J. , Griffiths, I.R. and McLaughlin, M. (2010) Modulation of rumpshaker phenotype with wild-type PLP/DM20 suggests several pathogenic mechanisms. Journal of Neuroscience Research, 88(10), pp. 2135-2145. (doi: 10.1002/jnr.22379)

Evans, R.D., Weston, D.A., McLaughlin, M. and Brown, A.M. (2010) A non-linear regression analysis method for quantitative resolution of the stimulus-evoked compound action potential from rodent optic nerve. Journal of Neuroscience Methods, 188(1), pp. 174-178. (doi: 10.1016/j.jneumeth.20%U 10.02.004)

2009

Lowrie, M., Penderis, J., McLaughlin, M. , Eckersall, P.D. and Anderson, T.J. (2009) Steroid responsive meningitis-arteritis: a prospective study of potential disease markers, prednisolone treatment, and long-term outcome in 20 dogs (2006-2008). Journal of Veterinary Internal Medicine, 23(4), pp. 862-870. (doi: 10.1111/j.1939-1676.2009.0337.x)

Hogan, V., White, K., Edgar, J. , McGill, A., Karim, S., McLaughlin, M. , Griffiths, I., Turnbull, D. and Nichols, P. (2009) Increase in mitochondrial density within axons and supporting cells in response to demyelination in the Plp1 mouse model. Journal of Neuroscience Research, 87(2), pp. 452-459. (doi: 10.1002/jnr.21867)

Edgar, J.M. , McLaughlin, M. , Werner, H.B., McCulloch, M.C., Barrie, J.A., Brown, A., Faichney, A., Snaidero, N., Nave, K.A. and Griffiths, I.R. (2009) Early Ultrastructural Defects of Axons and Axon-Glia Junctions in Mice Lacking Expression of Cnp1. Glia, 57(16), pp. 1815-1824. (doi: 10.1002/glia.20893)

Lowrie, M., Penderis, J., Eckersall, P.D., McLaughlin, M. , Mellor, D. and Anderson, T.J. (2009) The role of acute phase proteins in diagnosis and management of steroid-responsive meningitis arteritis in dogs. Veterinary Journal, 182(1), pp. 125-130. (doi: 10.1016/j.tvjl.2008.05.001)

2008

Thomson, C.E., McCulloch, M., Sorenson, A., Barnett, S.C. , Seed, B.V., Griffiths, I.R. and McLaughlin, M. (2008) Myelinated, synapsing cultures of murine spinal cord - validation as an in vitro model of the central nervous system. European Journal of Neuroscience, 28(8), pp. 1518-1535. (doi: 10.1111/j.1460-9568.2008.06415.x)

2007

Karim, S.A., Barrie, J.A., McCulloch, M.C., Montague, M., Edgar, J.M., Kirkham, D., Anderson, T.J. , Nave, K.A., Griffiths, I.R. and Mclaughlin, M. (2007) PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease. Glia, 55(4), pp. 341-351. (doi: 10.1002/glia.20465)

McLaughlin, M., Karim, S., Montague, P., Barrie, J., Kirkham, D., Griffiths, I. and Edgar, J. (2007) Genetic background influences UPR but not PLP processing in the rumpshaker model of PMD/SPG2. Neurochemical Research, 32, pp. 167-176. (doi: 10.1007/s11064-006-9122-y)

2006

Wyse, C.A., Nixon, C., McLaughlin, M. , Dowell, F.J. and Philbey, A.W. (2006) Evidence for the expression and enzymatic activity of haem oxygenase-1 in the lungs of horses. Veterinary Record, 158(23), pp. 795-798. (doi: 10.1136/vr.158.23.795)

Fowler, J., Edgar, J., Pringle, A., McLaughlin, M., McCulloch, J., Griffiths, I., Garbern, J., Nave, K. and Dewar, D. (2006) alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-mediated excitotoxic axonal damage is attenuated in the absence of myelin proteolipid protein. Journal of Neuroscience Research, 84, pp. 68-77. (doi: 10.1002/jnr.20859)

McLaughlin, M., Barrie, J., Karim, S., Montague, P., Edgar, J., Kirkham, D., Thomson, C. and Griffiths, I. (2006) Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation. Glia, 53, pp. 715-722. (doi: 10.1002/glia.20325)

2005

Montague, P., McCallion, A., Barrie, J., Edgar, J., McLaughlin, M., Davies, R. and Griffiths, I. (2005) Characterization of the murine splice variant Mobp155: Developmental CNS expression pattern and subcellular localization of epitope-tagged protein. Glia, 50, pp. 80-85. (doi: 10.1002/glia.20155)

2004

Edgar, J. et al. (2004) Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia. Journal of Cell Biology, 166(1), pp. 121-131. (doi: 10.1083/jcb.200312012) (PMID:15226307) (PMCID:PMC2172145)

Edgar, J., McLaughlin, M., Barrie, J., McCulloch, M., Garbern, J. and Griffiths, I. (2004) Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene. Acta Neuropathologica, 107, pp. 331-335. (doi: 10.1007/s00401-003-0808-9)

2003

Al-Saktawi, K., McLaughlin, M., Klugmann, M., Schneider, A., Barrie, J., McCulloch, M., Montague, P., Kirkham, D., Nave, K. and Griffiths, I. (2003) Genetic background determines phenotypic severity of the Plp rumpshaker mutation. Journal of Neuroscience Research, 72, pp. 12-24. (doi: 10.1002/jnr.10561)

2002

Yool, D. , Montague, P., McLaughlin, M., McCulloch, M., Edgar, J., Nave, K., Davies, R., Griffiths, I. and McCallion, A. (2002) Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform. Glia, 39(3), pp. 256-267. (doi: 10.1002/glia.10103) (PMID:12203392)

McLaughlin, M., Hunter, D., Thomson, C., Yool, D. , Kirkham, D., Freer, A. and Griffiths, I. (2002) Evidence for possible interactions between PLP and DM20 within the myelin sheath. Glia, 39(1), pp. 31-36. (doi: 10.1002/glia.10091) (PMID:12112373)

2001

Yool, D.A. , Klugmann, M., McLaughlin, M., Vouyiouklis, D.A., Dimou, L., Barrie, J.A., McCulloch, M.C., Nave, K.-A. and Griffiths, I.R. (2001) Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons. Journal of Neuroscience Research, 63(2), pp. 151-164. (doi: 10.1002/1097-4547(20010115)63:2<151::AID-JNR1007>3.0.CO;2-Y) (PMID:11169625)

O'Neill, C., Anderton, B., Georgopoulou, N., McLaughlin, M. , McFarlane, I. and Breen, K. C. (2001) The role of post-translational modification in ϐ-amyloid precursor protein processing. Biochemical Society Symposia, 67, pp. 23-36. (doi: 10.1042/bss0670023) (PMID:11447837)

2000

Shinomura, T., del Río, E., Breen, K.C., Downes, C.P. and McLaughlin, M. (2000) Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes. British Journal of Pharmacology, 131(5), pp. 1011-1018. (doi: 10.1038/sj.bjp.0703651) (PMID:11053224) (PMCID:PMC1572410)

1999

McLaughlin, M. and Breen, K.C. (1999) Protein kinase C activation potentiates the rapid secretion of the amyloid precursor protein from rat cortical synaptosomes. Journal of Neurochemistry, 72(1), pp. 273-81. (doi: 10.1046/j.1471-4159.1999.0720273.x) (PMID:9886079)

Cousin, M. A., McLaughlin, M. and Nicholls, D. G. (1999) Protein kinase C modulates field-evoked transmitter release from cultured rat cerebellar granule cells via a dendrotoxin-sensitive K+channel. European Journal of Neuroscience, 11(1), pp. 101-109. (doi: 10.1046/j.1460-9568.1999.00412.x) (PMID:9987015)

Del Río, E., McLaughlin, M. , Downes, C.P. and Nicholls, D.G. (1999) Differential coupling of G-protein-linked receptors to Ca2+mobilization through inositol(1,4,5)trisphosphate or ryanodine receptors in cerebellar granule cells in primary culture. European Journal of Neuroscience, 11(9), pp. 3015-3022. (doi: 10.1046/j.1460-9568.1999.00714.x) (PMID:10510166)

McLaughlin, M. , Inglis, F.M., Ross, B.M., Breen, K.C. and McCulloch, J. (1999) Modest cholinergic deafferentation fails to alter hippocampal G-proteins. Neurochemistry International, 35(1), pp. 59-64. (doi: 10.1016/S0197-0186(99)00033-9) (PMID:10403430)

1996

McLaughlin, M. , Brunton, V., Morrison, V., Rae, A., Cooke, T. and Bartlett, J. (1996) Growth inhibition of gastric cancer cell lines by the tyrphostin RG13022 and its effects on intracellular signalling. International Journal of Oncology, 8(3), pp. 589-596. (doi: 10.3892/ijo.8.3.589) (PMID:21544401)

1993

Ross, B. M., McLaughlin, M. , Roberts, M., Milligan, G. , McCulloch, J. and Knowler, J. T. (1993) Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease. Brain Research, 622(1-2), pp. 35-42. (doi: 10.1016/0006-8993(93)90798-R) (PMID:8242380)

1991

McLaughlin, M. , Ross, B. M., Milligan, G. , McCulloch, J. and Knowler, J. T. (1991) Robustness of G proteins in Alzheimer's disease: an immunoblot study. Journal of Neurochemistry, 57(1), pp. 9-14. (doi: 10.1111/j.1471-4159.1991.tb02092.x) (PMID:1904911)

Articles

O'Reilly, E. L. et al. (2024) Biomarker and proteome analysis of milk from dairy cows with clinical mastitis: determining the effect of different bacterial pathogens on the response to infection. Research in Veterinary Science, 172, 105240. (doi: 10.1016/j.rvsc.2024.105240) (PMID:38608347)

Huang, Y., Jonsson, N. N. , McLaughlin, M. , Burchmore, R. , Johnson, P. C.D. , Jones, R. , McGill, S., Brady, N., Weidt, S. and Eckersall, D. (2023) Quantitative TMT-based proteomics revealing host, dietary and microbial proteins in bovine faeces including barley serpin Z4, a prominent component in the head of beer. Journal of Proteomics, 285, 104941. (doi: 10.1016/j.jprot.2023.104941) (PMID:37285906)

Peinado-Izaguerri, J. , Zarzuela, E., McLaughlin, M. , Small, A. C., Riva, F., McKeegan, D. E.F. , Bain, M. , Muñoz, J., Bhide, M. and Preston, T. (2023) A novel dynamic proteomics approach for the measurement of broiler chicken protein fractional synthesis rate. Rapid Communications in Mass Spectrometry, 37(10), e9497. (doi: 10.1002/rcm.9497) (PMID:36851885)

Nguyen, T. X. et al. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part I: serum proteomes. Journal of Proteomics, 270, 104740. (doi: 10.1016/j.jprot.2022.104740) (PMID:36191802)

Nguyen, T. X., Agazzo, A., McGill, S., Weidt, S., Han, Q. H., Gelemanović, A., McLaughlin, M. , Savoini, G., Eckersall, P. D. and Burchmore, R. (2023) Proteomic changes associated with maternal dietary low ω6:ω3 ratio in piglets supplemented with seaweed part II: ileum proteomes. Journal of Proteomics, 270, 104739. (doi: 10.1016/j.jprot.2022.104739) (PMID:36174954)

Nguyen, T. X. et al. (2022) Abundance of plasma proteins in response to divergent ratios of dietary ω6:ω3 fatty acids in gestating and lactating sows using a quantitative proteomics approach. Journal of Proteomics, 260, 104562. (doi: 10.1016/j.jprot.2022.104562) (PMID:35314360)

McGonigal, R. , Barrie, J. A., Yao, D., Black, L. E. , McLaughlin, M. and Willison, H. J. (2021) Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of Neurochemistry, 158(2), pp. 217-232. (doi: 10.1111/jnc.15365) (PMID:33864399)

Almeida, A. M. et al. (2021) Domestic animal proteomics in the 21st century: A global retrospective and viewpoint analysis. Journal of Proteomics, 241, 104220. (doi: 10.1016/j.jprot.2021.104220) (PMID:33838350)

Baka, R. et al. (2021) Quantitative proteomics of cerebrospinal fluid using tandem mass tags in dogs with recurrent epileptic seizures. Journal of Proteomics, 231, 103997. (doi: 10.1016/j.jprot.2020.103997) (PMID:33011347)

Horvatić, A. et al. (2021) Multi-omics approach to elucidate cerebrospinal fluid changes in dogs with intervertebral disc herniation. International Journal of Molecular Sciences, 22(21), 11678. (doi: 10.3390/ijms222111678)

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

McNaught, K. A., Morris, J. S. and McLaughlin, M. (2020) Preliminary assessment of serum clusterin as a potential biomarker for canine lymphoma. Veterinary and Comparative Oncology, 18(3), pp. 292-302. (doi: 10.1111/vco.12550) (PMID:31654603)

Gruenenfelder, F. I. et al. (2020) Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease. Brain, 143(5), pp. 1383-1399. (doi: 10.1093/brain/awaa080) (PMID:32419025) (PMCID:PMC7462093)

Qi, Y., Montague, P., Loney, C. , Campbell, C., Shafie, I., Anderson, T. and McLaughlin, M. (2019) In vitro evidence consistent with an interaction between wild type and a mutant SOD 1 protein associated with canine degenerative myelopathy. European Journal of Neuroscience, 50(12), pp. 3896-3905. (doi: 10.1111/ejn.14526) (PMID:31336405)

Hough, D. , Robinson, J.E. , Bellingham, M. , Fleming, L.M., McLaughlin, M. , Jama, K., Haraldsen, I.R.H., Solbakk, A.K. and Evans, N.P. (2019) Peripubertal GnRH and testosterone co-treatment leads to increased familiarity preferences in male sheep. Psychoneuroendocrinology, 108, pp. 70-77. (doi: 10.1016/j.psyneuen.2019.06.008) (PMID:31229635) (PMCID:PMC6712355)

Gutierrez-Quintana, R. , McLaughlin, M. , Grau Roma, L., Hammond, G., Gray, A. and Lowrie, M. (2019) Spongiform leucoencephalomyelopathy in border terriers: clinical, electrophysiological and imaging features. Veterinary Record, 185, 375. (doi: 10.1136/vr.105240) (PMID:31346136)

Bijland, S. et al. (2019) An in vitro model for studying CNS white matter: functional properties and experimental approaches. F1000Research, 8, 117. (doi: 10.12688/f1000research.16802.1) (PMID:31069065) (PMCID:PMC6489523)

McGonigal, R. , Barrie, J.A., Yao, D., McLaughlin, M. , Cunningham, M.E. , Rowan, E.G. and Willison, H.J. (2019) Glial sulfatides and neuronal complex gangliosides are functionally interdependent in maintaining myelinating axon integrity. Journal of Neuroscience, 39(1), pp. 63-77. (doi: 10.1523/JNEUROSCI.2095-18.2018) (PMID:30446529) (PMCID:PMC6325269)

Wyse, C.A., Zhang, X., McLaughlin, M. , Biello, S.M. , Hough, D., Bellingham, M. , Curtis, A.M., Robinson, J.E. and Evans, N.P. (2018) Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: effects of photoperiod, environment and weaning. Physiology and Behavior, 194, pp. 362-370. (doi: 10.1016/j.physbeh.2018.06.001) (PMID:29894760)

Hough, D. , Bellingham, M. , Haraldsen, J.R., McLaughlin, M. , Robinson, J.E. , Solbakk, A.K. and Evans, N.P. (2017) A reduction in long-term spatial memory persists after discontinuation of peripubertal GnRH agonist treatment in sheep. Psychoneuroendocrinology, 77, pp. 1-8. (doi: 10.1016/j.psyneuen.2016.11.029) (PMID:27987429) (PMCID:PMC5333793)

Hough, D. , Bellingham, M. , Haraldsen, I.R.H., McLaughlin, M. , Rennie, M., Robinson, J.E. , Solbakk, A.K. and Evans, N.P. (2017) Spatial memory is impaired by peripubertal GnRH agonist treatment and testosterone replacement in sheep. Psychoneuroendocrinology, 75, pp. 173-182. (doi: 10.1016/j.psyneuen.2016.10.016) (PMID:27837697) (PMCID:PMC5140006)

Mudaliar, M. et al. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. Molecular BioSystems, 12(9), pp. 2748-2761. (doi: 10.1039/C6MB00290K) (PMID:27412694) (PMCID:PMC5048399)

Braceland, M., McLoughlin, M.F., Tinsley, J., Wallace, C., Cockerill, D., McLaughlin, M. and Eckersall, P.D. (2015) Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. Journal of Fish Diseases, 28(9), pp. 821-831. (doi: 10.1111/jfd.12296) (PMID:25168106)

Shafie, I. N.F., McLaughlin, M. , Burchmore, R. , Lim, M. A. A., Montague, P., Johnston, P. E.J. , Penderis, J. and Anderson, T. J. (2014) The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog. Cell Stress and Chaperones, 19(3), pp. 311-320. (doi: 10.1007/s12192-013-0457-4)

Almeida, A.M. et al. (2014) Animal board invited review: advances in proteomics for animal and food sciences. Animal, 9(1), pp. 1-17. (doi: 10.1017/S1751731114002602) (PMID:25359324) (PMCID:PMC4301196)

Albalat, A., Husi, H., Siwy, J., Nally, J. E., McLaughlin, M. , Eckersall, P. D. and Mullen, W. (2014) Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals. Current Protein and Peptide Science, 15(1), pp. 23-35. (doi: 10.2174/1389203715666140221123920) (PMID:24555889)

Ghazali, M., Koh-Tan, H. H., McLaughlin, M. , Montague, P., Jonsson, N. N. and Eckersall, P. (2014) Alkaline phosphatase in nasal secretion of cattle: biochemical and molecular characterisation. BMC Veterinary Research, 10(1), 204. (doi: 10.1186/s12917-014-0204-9) (PMID:25927913) (PMCID:PMC4173004)

McQueen, J., Reimer, M.M., Holland, P.R., Manso, Y., McLaughlin, M. , Fowler, J.H. and Horsburgh, K. (2014) Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion. PLoS ONE, 9(2), e87227. (doi: 10.1371/journal.pone.0087227) (PMID:24498301) (PMCID:PMC3911923)

Shafie, I.N.F., Anderson, T.J. , Penderis, J., Eckersall, P.D. and McLaughlin, M. (2013) A protocol for the management of canine cerebrospinal fluid for the proteomic assessment of putative biomarkers. Veterinary Journal, 197(3), pp. 836-841. (doi: 10.1016/j.tvjl.2013.05.039)

Karim, S., Barrie, J., McCulloch, M., Montague, P., Edgar, J.M. , Iden, D.L., Anderson, T.J. , Nave, K.-A., Griffiths, I.R. and McLaughlin, M. (2010) PLP/DM20 expression and turnover in a transgenic mouse model of pelizaeus-merzbacher disease. Glia, 58(14), pp. 1727-1738. (doi: 10.1002/glia.21043)

Barrie, J.A., Montague, P., Karim, S.A., Kirkham, D., Nave, K.-A., Anderson, T.J. , Griffiths, I.R. and McLaughlin, M. (2010) Modulation of rumpshaker phenotype with wild-type PLP/DM20 suggests several pathogenic mechanisms. Journal of Neuroscience Research, 88(10), pp. 2135-2145. (doi: 10.1002/jnr.22379)

Evans, R.D., Weston, D.A., McLaughlin, M. and Brown, A.M. (2010) A non-linear regression analysis method for quantitative resolution of the stimulus-evoked compound action potential from rodent optic nerve. Journal of Neuroscience Methods, 188(1), pp. 174-178. (doi: 10.1016/j.jneumeth.20%U 10.02.004)

Lowrie, M., Penderis, J., McLaughlin, M. , Eckersall, P.D. and Anderson, T.J. (2009) Steroid responsive meningitis-arteritis: a prospective study of potential disease markers, prednisolone treatment, and long-term outcome in 20 dogs (2006-2008). Journal of Veterinary Internal Medicine, 23(4), pp. 862-870. (doi: 10.1111/j.1939-1676.2009.0337.x)

Hogan, V., White, K., Edgar, J. , McGill, A., Karim, S., McLaughlin, M. , Griffiths, I., Turnbull, D. and Nichols, P. (2009) Increase in mitochondrial density within axons and supporting cells in response to demyelination in the Plp1 mouse model. Journal of Neuroscience Research, 87(2), pp. 452-459. (doi: 10.1002/jnr.21867)

Edgar, J.M. , McLaughlin, M. , Werner, H.B., McCulloch, M.C., Barrie, J.A., Brown, A., Faichney, A., Snaidero, N., Nave, K.A. and Griffiths, I.R. (2009) Early Ultrastructural Defects of Axons and Axon-Glia Junctions in Mice Lacking Expression of Cnp1. Glia, 57(16), pp. 1815-1824. (doi: 10.1002/glia.20893)

Lowrie, M., Penderis, J., Eckersall, P.D., McLaughlin, M. , Mellor, D. and Anderson, T.J. (2009) The role of acute phase proteins in diagnosis and management of steroid-responsive meningitis arteritis in dogs. Veterinary Journal, 182(1), pp. 125-130. (doi: 10.1016/j.tvjl.2008.05.001)

Thomson, C.E., McCulloch, M., Sorenson, A., Barnett, S.C. , Seed, B.V., Griffiths, I.R. and McLaughlin, M. (2008) Myelinated, synapsing cultures of murine spinal cord - validation as an in vitro model of the central nervous system. European Journal of Neuroscience, 28(8), pp. 1518-1535. (doi: 10.1111/j.1460-9568.2008.06415.x)

Karim, S.A., Barrie, J.A., McCulloch, M.C., Montague, M., Edgar, J.M., Kirkham, D., Anderson, T.J. , Nave, K.A., Griffiths, I.R. and Mclaughlin, M. (2007) PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease. Glia, 55(4), pp. 341-351. (doi: 10.1002/glia.20465)

McLaughlin, M., Karim, S., Montague, P., Barrie, J., Kirkham, D., Griffiths, I. and Edgar, J. (2007) Genetic background influences UPR but not PLP processing in the rumpshaker model of PMD/SPG2. Neurochemical Research, 32, pp. 167-176. (doi: 10.1007/s11064-006-9122-y)

Wyse, C.A., Nixon, C., McLaughlin, M. , Dowell, F.J. and Philbey, A.W. (2006) Evidence for the expression and enzymatic activity of haem oxygenase-1 in the lungs of horses. Veterinary Record, 158(23), pp. 795-798. (doi: 10.1136/vr.158.23.795)

Fowler, J., Edgar, J., Pringle, A., McLaughlin, M., McCulloch, J., Griffiths, I., Garbern, J., Nave, K. and Dewar, D. (2006) alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-mediated excitotoxic axonal damage is attenuated in the absence of myelin proteolipid protein. Journal of Neuroscience Research, 84, pp. 68-77. (doi: 10.1002/jnr.20859)

McLaughlin, M., Barrie, J., Karim, S., Montague, P., Edgar, J., Kirkham, D., Thomson, C. and Griffiths, I. (2006) Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation. Glia, 53, pp. 715-722. (doi: 10.1002/glia.20325)

Montague, P., McCallion, A., Barrie, J., Edgar, J., McLaughlin, M., Davies, R. and Griffiths, I. (2005) Characterization of the murine splice variant Mobp155: Developmental CNS expression pattern and subcellular localization of epitope-tagged protein. Glia, 50, pp. 80-85. (doi: 10.1002/glia.20155)

Edgar, J. et al. (2004) Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia. Journal of Cell Biology, 166(1), pp. 121-131. (doi: 10.1083/jcb.200312012) (PMID:15226307) (PMCID:PMC2172145)

Edgar, J., McLaughlin, M., Barrie, J., McCulloch, M., Garbern, J. and Griffiths, I. (2004) Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene. Acta Neuropathologica, 107, pp. 331-335. (doi: 10.1007/s00401-003-0808-9)

Al-Saktawi, K., McLaughlin, M., Klugmann, M., Schneider, A., Barrie, J., McCulloch, M., Montague, P., Kirkham, D., Nave, K. and Griffiths, I. (2003) Genetic background determines phenotypic severity of the Plp rumpshaker mutation. Journal of Neuroscience Research, 72, pp. 12-24. (doi: 10.1002/jnr.10561)

Yool, D. , Montague, P., McLaughlin, M., McCulloch, M., Edgar, J., Nave, K., Davies, R., Griffiths, I. and McCallion, A. (2002) Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform. Glia, 39(3), pp. 256-267. (doi: 10.1002/glia.10103) (PMID:12203392)

McLaughlin, M., Hunter, D., Thomson, C., Yool, D. , Kirkham, D., Freer, A. and Griffiths, I. (2002) Evidence for possible interactions between PLP and DM20 within the myelin sheath. Glia, 39(1), pp. 31-36. (doi: 10.1002/glia.10091) (PMID:12112373)

Yool, D.A. , Klugmann, M., McLaughlin, M., Vouyiouklis, D.A., Dimou, L., Barrie, J.A., McCulloch, M.C., Nave, K.-A. and Griffiths, I.R. (2001) Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons. Journal of Neuroscience Research, 63(2), pp. 151-164. (doi: 10.1002/1097-4547(20010115)63:2<151::AID-JNR1007>3.0.CO;2-Y) (PMID:11169625)

O'Neill, C., Anderton, B., Georgopoulou, N., McLaughlin, M. , McFarlane, I. and Breen, K. C. (2001) The role of post-translational modification in ϐ-amyloid precursor protein processing. Biochemical Society Symposia, 67, pp. 23-36. (doi: 10.1042/bss0670023) (PMID:11447837)

Shinomura, T., del Río, E., Breen, K.C., Downes, C.P. and McLaughlin, M. (2000) Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes. British Journal of Pharmacology, 131(5), pp. 1011-1018. (doi: 10.1038/sj.bjp.0703651) (PMID:11053224) (PMCID:PMC1572410)

McLaughlin, M. and Breen, K.C. (1999) Protein kinase C activation potentiates the rapid secretion of the amyloid precursor protein from rat cortical synaptosomes. Journal of Neurochemistry, 72(1), pp. 273-81. (doi: 10.1046/j.1471-4159.1999.0720273.x) (PMID:9886079)

Cousin, M. A., McLaughlin, M. and Nicholls, D. G. (1999) Protein kinase C modulates field-evoked transmitter release from cultured rat cerebellar granule cells via a dendrotoxin-sensitive K+channel. European Journal of Neuroscience, 11(1), pp. 101-109. (doi: 10.1046/j.1460-9568.1999.00412.x) (PMID:9987015)

Del Río, E., McLaughlin, M. , Downes, C.P. and Nicholls, D.G. (1999) Differential coupling of G-protein-linked receptors to Ca2+mobilization through inositol(1,4,5)trisphosphate or ryanodine receptors in cerebellar granule cells in primary culture. European Journal of Neuroscience, 11(9), pp. 3015-3022. (doi: 10.1046/j.1460-9568.1999.00714.x) (PMID:10510166)

McLaughlin, M. , Inglis, F.M., Ross, B.M., Breen, K.C. and McCulloch, J. (1999) Modest cholinergic deafferentation fails to alter hippocampal G-proteins. Neurochemistry International, 35(1), pp. 59-64. (doi: 10.1016/S0197-0186(99)00033-9) (PMID:10403430)

McLaughlin, M. , Brunton, V., Morrison, V., Rae, A., Cooke, T. and Bartlett, J. (1996) Growth inhibition of gastric cancer cell lines by the tyrphostin RG13022 and its effects on intracellular signalling. International Journal of Oncology, 8(3), pp. 589-596. (doi: 10.3892/ijo.8.3.589) (PMID:21544401)

Ross, B. M., McLaughlin, M. , Roberts, M., Milligan, G. , McCulloch, J. and Knowler, J. T. (1993) Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease. Brain Research, 622(1-2), pp. 35-42. (doi: 10.1016/0006-8993(93)90798-R) (PMID:8242380)

McLaughlin, M. , Ross, B. M., Milligan, G. , McCulloch, J. and Knowler, J. T. (1991) Robustness of G proteins in Alzheimer's disease: an immunoblot study. Journal of Neurochemistry, 57(1), pp. 9-14. (doi: 10.1111/j.1471-4159.1991.tb02092.x) (PMID:1904911)

Book Sections

Eckersall, P. D. and McLaughlin, M. (2011) Proteomics in animal health and disease. In: Eckersall, P. D. and Whitfield, P. D. (eds.) Methods in Animal Proteomics. Wiley-Blackwell, pp. 243-318. ISBN 9780813817910 (doi: 10.1002/9780470960660.ch10)

Conference Proceedings

Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Wilson, D., Herzyk, P. , Eckersall, P. and Zadoks, R. (2015) Using label-free quantitative proteomics and untargeted metabolomics to study bovine mastitis. In: Science with Impact – BSAS Annual Conference 2015, University of Chester, UK, 14-15 Apr 2015, p. 70. (doi: 10.1017/S2040470015000023)

Mudaliar, M. , Thomas, F., McLaughlin, M. , Burchmore, R. , Herzyk, P. , Eckersall, P. and Zadoks, R. (2014) Integrative label-free quantitative proteomics study in mastitis. In: Final Showcase Meeting of Farm Animal Proteomics, Milan, Italy, 17-18 Nov 2014, pp. 98-101. ISBN 9789086868100 (doi: 10.3920/978-90-8686-810-0)