School of Veterinary Medicine

Prof Clare Knottenbelt

Prof Clare M Knottenbelt
  • Professor of Small Animal Medicine and Oncology (Small Animal Clinical Sciences)
  • Associate Academic (Institute of Biodiversity Animal Health and Comparative Medicine)

telephone: 01413307459
email: Clare.Knottenbelt@glasgow.ac.uk


My major areas of interest are the prevention and treatment of cancer in domestic pets and the use of evidence based medicine to support management decisions. I have an interest in the role of non-steroidal anti-inflammatory drugs (COX inhibitors) in the management of cancer both as palliative care and as part of treatment protocols. In 1999 we demonstrated that the COX inhibitor piroxicam could be used in the management of rectal polyps (JSAP 2000; 41 393-397) which have been shown to express COX 2 (JSAP 2006; 47, 196-200), and have subsequently shown that non-steroidals inhibit the growth of canine cancer cell lines (JSAP 2006; 47, 14-20).

My recent research study involves assessment of hair nicotine in dogs exposed to second hand smoke. The link between disease and exposure to tobacco smoke has proved difficult to elucidate and further work is underway to establish better method of

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Number of items: 20.

2012

Bawazeer , S., Watson, D.G., and Knottenbelt, C. (2012) Determination of nicotine exposure in dogs subjected to passive smoking using methanol extraction of hair followed by hydrophilic interaction chromatography with Fourier transform mass spectrometry. Talanta, 88 . pp. 408-411. ISSN 0039-9140 (doi:10.1016/j.talanta.2011.11.008)

2010

Arteaga, A., Dhand, N.K., McCann, T., Knottenbelt, C.M. , Tebb, A.J., Evans, H., Eckersall, P.D. , and Ramsey, I.K. (2010) Monitoring the response of canine hyperadrenocorticism to trilostane treatment by assessment of acute phase protein concentrations. Journal of Small Animal Practice, 51 (4). pp. 204-209. ISSN 0022-4510 (doi:10.1111/j.1748-5827.2009.00863.x)

Helm, J.R., and Knottenbelt, C. (2010) Blood transfusions in dogs and cats 1. Indications. In Practice, 32 (5). pp. 184-189. ISSN 0263-841X (doi:10.1136/inp.c2226)

Helm, J.R., and Knottenbelt, C. (2010) Blood transfusions in dogs and cats 2. Practicalities of blood collection and administration. In Practice, 32 (6). pp. 231-237. ISSN 0263-841X (doi:10.1136/inpract.32.6.231)

McLauchlan, G., Knottenbelt, C. , Augusto, M., Helm, J. , McGrotty, Y., and Ramsey, I. (2010) Retrospective evaluation of the effect of trilostane on insulin requirement and fructosamine concentration in eight diabetic dogs with hyperadrenocorticism. Journal of Small Animal Practice, 51 (12). pp. 642-648. ISSN 0022-4510 (doi:10.1111/j.1748-5827.2010.01005.x)

2006

Knottenbelt, C, Chambers, G, Gault, E, and Argyle, DJ (2006) The in vitro effects of piroxicam and meloxicam on canine cell lines. Journal of Small Animal Practice, 47 . pp. 14-20. ISSN 0022-4510

Knottenbelt, C, Mellor, D , Nixon, C, Thompson, H , and Argyle, DJ (2006) Cohort study of COX-1 and COX-2 expression in canine rectal and bladder tumours. Journal of Small Animal Practice, 47 . pp. 196-200. ISSN 0022-4510

2005

Bell, R, Mellor, DJ , Ramsey, I , and Knottenbelt, C (2005) Decreased sodium : potassium ratios in cats: 49 cases. Veterinary Clinical Pathology, 34 . pp. 110-114.

McGrotty, YL, Arteaga, A, Knottenbelt, CM , Ramsey, IK , and Eckersall, PD (2005) Haptoglobin concentrations in dogs undergoing trilostane treatment for hyperadrenocorticism. Veterinary Clinical Pathology, 34 . pp. 255-258.

2004

McGrotty, Y.L., Knottenbelt, C.M. , Ramsey, I.K. , Reid, S.W.J. , and Eckersall, P.D. (2004) Evaluation of a rapid assay for canine C-reactive protein. The Veterinary Record, 154 . pp. 175-176. ISSN 0042-4900

Nunn, F, Cave, IA, Knottenbelt, C , and Poxton, IR (2004) Association between Key-Gaskell syndrome and infection by Clostridium botulinum type C/D. The Veterinary Record, 155 . pp. 111-115. ISSN 0042-4900

2003

Cave, TA, Knottenbelt, C , Mellor, DJ , Nunn, F, Nart, P, and Reid, SWJ (2003) Outbreak of dysautonomia (Key-Gaskell syndrome) in a closed colony of pet cats. The Veterinary Record, 153 . pp. 387-392. ISSN 0042-4900

Long, SN, Michieletto, A, Anderson, TJ , Williams, A, and Knottenbelt, CM (2003) Suspected pituitary apoplexy in a German shorthaired pointer - Abstract. Journal of Small Animal Practice, 44 . pp. 497-502. ISSN 0022-4510

McGrotty, YL, Knottenbelt, CM , Doust, RT, Ramsey, IK , and Sullivan, M (2003) Complications of open peritoneal drainage in nine dogs with gastrointestinal leakage. Irish Veterinary Journal, 56 . pp. 354-360.

McGrotty, YL, Knottenbelt, CM , Ramsey, IK , Reid, SWJ , and Eckersall, PD (2003) Haptoglobin concentrations in a canine hospital population. The Veterinary Record, 152 . p. 562. ISSN 0042-4900

McGrotty, YL, Ramsey, IK , and Knottenbelt, CM (2003) Diagnosis and management of hepatic copper accumulation in a Skye terrier. Journal of Small Animal Practice, 44 . pp. 85-89. ISSN 0022-4510

2002

Knottenbelt, CM (2002) The feline AB blood group system and its importance in transfusion medicine. Journal of Feline Medicine and Surgery, 4 (2). pp. 69-76. (doi:10.1053/jfms.2001.0162)

Knottenbelt, CM, and Herrtage, ME (2002) Use of proligestone in the management of three German shepherd dogs with pituitary dwarfism. Journal of Small Animal Practice, 43 . pp. 164-170. ISSN 0022-4510

McGrotty, YL, and Knottenbelt, CM (2002) Oesophageal stricture in a cat due to oral administration of tetracyclines. Journal of Small Animal Practice, 43 . pp. 221-223. ISSN 0022-4510

2001

Knottenbelt, C (2001) Investigation of anaemia in dogs. In Practice, 23 . p. 306.

This list was generated on Sat May 26 14:22:40 2012 BST.
  • Nicotine concentrations in the hair of dogs and cats exposed to Environmental Tobacco Smoke
    Petsavers
    2010 - 2011
     
  • Quasispecies evolution in the progression of FIV infection
    Wellcome Trust
    2009 - 2015
     
  • Study into the synergistic effects of non-steroidal anti-inflammatory drugs on telomerase activity in canine transitional cell carcinoma
    The Pet Plan Charitable Trust
    2007 - 2007
     
  • Rehoming Centre
    The Dogs Trust
    2006 - 2012
     

Invited International Presentations

  • 2011: Istanbul, Turkey - FECAVA Conference

Prizes, Awards and Distinctions

  • 2000: Petsavers - Best research paper in JSAP

Professional Learned Society

  • 2009 - 1970: VET Trust - Director