Dr Mike Edward

  • Honorary Senior Research Fellow (Undergraduate Medical School)

telephone: 01413304007
email: Mike.Edward@glasgow.ac.uk

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Effect of 4-methylumbelliferone on hyaluronan synthesis by dermatomyositis and scleromyxedema-like dialysis patient fibroblasts within a living skin equivalent: potential mucinosis/fibrosis treatment
    British Skin Foundation
    2006 - 2007
     
  • Proof of Concept initiative: Replacing Animals with new tissue models for mechanism-based drug development in the post-genome era
    Scottish Enterprise
    2005 - 2006
     

Publications

List by: Type | Date

Jump to: 2015 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2005 | 2003 | 2001
Number of items: 19.

2015

Sun, P., Dong, L., MacDonald, A. I., Akbari, S., Edward, M., Hodgins, M. B., Johnstone, S. R., and Graham, S. V. (2015) HPV16 E6 controls the gap junction protein Cx43 in cervical tumour cells. Viruses, 7(10), pp. 5243-5256. (doi:10.3390/v7102871) (PMID:26445057) (PMCID:PMC4632379)

2013

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73(15), pp. 4674-4686. (doi:10.1158/0008-5472.CAN-12-4545)

2012

MacDonald, A.I. et al. (2012) A functional interaction between the MAGUK protein hDlg and the gap junction protein Connexin 43 in cervical tumour cells. Biochemical Journal, 446(1), pp. 9-21. (doi:10.1042/BJ20111144)

Pasonen-Seppänen, S., Takabe, P., Edward, M., Rauhala, L., Rilla, K., Tammi, M., and Tammi, R. (2012) Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling. Histochemistry and Cell Biology, 138(6), pp. 895-911. (doi:10.1007/s00418-012-1000-x)

2011

Edward, M., Quinn, J.A., and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi:10.1111/j.1524-475X.2011.00678.x)

Katz, E., Verleyen, W., Blackmore, C.G., Edward, M., Smith, V.A., and Harrison, D.J. (2011) An analytical approach differentiates between individual and collective cancer invasion. Analytical Cellular Pathology, 34(1-2), pp. 35-48. (doi:10.3233/ACP-2011-0003)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71(3), pp. 747-757. (doi:10.1158/0008-5472.CAN-10-2267)

2010

Edward, M., Quinn, J.A., Burden, A.D., Newton, B.B., and Jardine, A.G. (2010) Effect of different classes of gadolinium-based contrast agents on control and nephrogenic systemic fibrosis-derived fibroblast proliferation. Radiology, 256(3), pp. 735-743. (doi:10.1148/radiol.10091131)

Edward, M., Quinn, J.A., Pasonen-Seppanen, S.M., McCann, B.A., and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162(6), pp. 1224-1232. (doi:10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103(3), p. 401. (doi:10.1038/sj.bjc.6605763)

2008

Edward, M., Quinn, J.A., Mukherjee, S., Jensen, M.B., Jardine, A.G., Mark, P., and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214(5), pp. 584-593. (doi:10.1002/path.2311)

2007

Amjad, S., Carachi, R., and Edward, M. (2007) Keratinocyte regulation of TGF-beta and connective tissue growth factor expression: A role in suppression of scar tissue formation. Wound Repair and Regeneration, 15, pp. 748-755. (doi:10.1111/j.1524-475X.2007.00281.x)

Burden, A., Edward, M., Fitzgerald, L., Leman, J., and Thind, C. (2007) Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum. British Journal of Dermatology, 156, pp. 473-479. (doi:10.1111/j.1365-2133.2006.07652.x)

2005

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2005) Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia. Molecular Cancer, 4, (doi:10.1186/1476-4598-4-31)

Clayton, R.F., Edward, M., Kandyba, E.E., Klenerman, P., Patel, A.H., Rinaldi, A., and Willberg, C. (2005) Liver cell lines for the study of hepatocyte functions and immunological response. Liver International, 25(2), pp. 389-402. (doi:10.1111/j.1478-3231.2005.01017.x)

Edward, M., Gillan, C., Micha, D., and Tammi, R. (2005) Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis, 26, pp. 1215-1223. (doi:10.1093/carcin/bgi064)

2003

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2003) The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression. Oncogene, 22, pp. 7969-7980. (doi:10.1038/sj.onc.1206709)

2001

Brownbridge, G., Edward, M., Gold, J., and Mackie, R. (2001) Evaluation of the use of tyrosinase-specific and melanA/MART-1-specific reverse transcriptase-coupled-polymerase chain reaction to detect melanoma cells in peripheral blood samples from 299 patients with malignant melanoma. British Journal of Dermatology, 144, pp. 279-287.

Edward, M. (2001) Melanoma cell-derived factors stimulate glycosaminoglycan synthesis by fibroblasts cultured as monolayers and within contracted collagen lattices. British Journal of Dermatology, 144, pp. 465-470.

This list was generated on Mon Feb 8 06:04:21 2016 GMT.
Jump to: Articles
Number of items: 19.

Articles

Sun, P., Dong, L., MacDonald, A. I., Akbari, S., Edward, M., Hodgins, M. B., Johnstone, S. R., and Graham, S. V. (2015) HPV16 E6 controls the gap junction protein Cx43 in cervical tumour cells. Viruses, 7(10), pp. 5243-5256. (doi:10.3390/v7102871) (PMID:26445057) (PMCID:PMC4632379)

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73(15), pp. 4674-4686. (doi:10.1158/0008-5472.CAN-12-4545)

MacDonald, A.I. et al. (2012) A functional interaction between the MAGUK protein hDlg and the gap junction protein Connexin 43 in cervical tumour cells. Biochemical Journal, 446(1), pp. 9-21. (doi:10.1042/BJ20111144)

Pasonen-Seppänen, S., Takabe, P., Edward, M., Rauhala, L., Rilla, K., Tammi, M., and Tammi, R. (2012) Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling. Histochemistry and Cell Biology, 138(6), pp. 895-911. (doi:10.1007/s00418-012-1000-x)

Edward, M., Quinn, J.A., and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi:10.1111/j.1524-475X.2011.00678.x)

Katz, E., Verleyen, W., Blackmore, C.G., Edward, M., Smith, V.A., and Harrison, D.J. (2011) An analytical approach differentiates between individual and collective cancer invasion. Analytical Cellular Pathology, 34(1-2), pp. 35-48. (doi:10.3233/ACP-2011-0003)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71(3), pp. 747-757. (doi:10.1158/0008-5472.CAN-10-2267)

Edward, M., Quinn, J.A., Burden, A.D., Newton, B.B., and Jardine, A.G. (2010) Effect of different classes of gadolinium-based contrast agents on control and nephrogenic systemic fibrosis-derived fibroblast proliferation. Radiology, 256(3), pp. 735-743. (doi:10.1148/radiol.10091131)

Edward, M., Quinn, J.A., Pasonen-Seppanen, S.M., McCann, B.A., and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162(6), pp. 1224-1232. (doi:10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103(3), p. 401. (doi:10.1038/sj.bjc.6605763)

Edward, M., Quinn, J.A., Mukherjee, S., Jensen, M.B., Jardine, A.G., Mark, P., and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214(5), pp. 584-593. (doi:10.1002/path.2311)

Amjad, S., Carachi, R., and Edward, M. (2007) Keratinocyte regulation of TGF-beta and connective tissue growth factor expression: A role in suppression of scar tissue formation. Wound Repair and Regeneration, 15, pp. 748-755. (doi:10.1111/j.1524-475X.2007.00281.x)

Burden, A., Edward, M., Fitzgerald, L., Leman, J., and Thind, C. (2007) Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum. British Journal of Dermatology, 156, pp. 473-479. (doi:10.1111/j.1365-2133.2006.07652.x)

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2005) Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia. Molecular Cancer, 4, (doi:10.1186/1476-4598-4-31)

Clayton, R.F., Edward, M., Kandyba, E.E., Klenerman, P., Patel, A.H., Rinaldi, A., and Willberg, C. (2005) Liver cell lines for the study of hepatocyte functions and immunological response. Liver International, 25(2), pp. 389-402. (doi:10.1111/j.1478-3231.2005.01017.x)

Edward, M., Gillan, C., Micha, D., and Tammi, R. (2005) Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis, 26, pp. 1215-1223. (doi:10.1093/carcin/bgi064)

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2003) The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression. Oncogene, 22, pp. 7969-7980. (doi:10.1038/sj.onc.1206709)

Brownbridge, G., Edward, M., Gold, J., and Mackie, R. (2001) Evaluation of the use of tyrosinase-specific and melanA/MART-1-specific reverse transcriptase-coupled-polymerase chain reaction to detect melanoma cells in peripheral blood samples from 299 patients with malignant melanoma. British Journal of Dermatology, 144, pp. 279-287.

Edward, M. (2001) Melanoma cell-derived factors stimulate glycosaminoglycan synthesis by fibroblasts cultured as monolayers and within contracted collagen lattices. British Journal of Dermatology, 144, pp. 465-470.

This list was generated on Mon Feb 8 06:04:21 2016 GMT.