Dr Mike Edward

  • Honorary Senior Research Fellow (Undergraduate Medical School)

telephone: 01413304007
email: Mike.Edward@glasgow.ac.uk

R510 Level 5
School of Medicine
Robertson Building
Glasgow G11 6NU


List all by: Type | Date

Jump to: 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2005 | 2003 | 2001
Number of items: 18.

2013

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73 (15). pp. 4674-4686. ISSN 0008-5472 (doi:10.1158/0008-5472.CAN-12-4545)

2012

MacDonald, A.I. et al. (2012) A functional interaction between the MAGUK protein hDlg and the gap junction protein Connexin 43 in cervical tumour cells. Biochemical Journal, 446 (1). pp. 9-21. ISSN 0264-6021 (doi:10.1042/BJ20111144)

Pasonen-Seppänen, S., Takabe, P., Edward, M., Rauhala, L., Rilla, K., Tammi, M., and Tammi, R. (2012) Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling. Histochemistry and Cell Biology, 138 (6). pp. 895-911. ISSN 0948-6143 (doi:10.1007/s00418-012-1000-x)

2011

Edward, M., Quinn, J.A., and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19 (3). pp. 379-386. ISSN 1067-1927 (doi:10.1111/j.1524-475X.2011.00678.x)

Katz, E., Verleyen, W., Blackmore, C.G., Edward, M., Smith, V.A., and Harrison, D.J. (2011) An analytical approach differentiates between individual and collective cancer invasion. Analytical Cellular Pathology, 34 (1-2). pp. 35-48. ISSN 2210-7177 (doi:10.3233/ACP-2011-0003)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71 (3). pp. 747-757. ISSN 0008-5472 (doi:10.1158/0008-5472.CAN-10-2267)

2010

Edward, M., Quinn, J.A., Burden, A.D., Newton, B.B., and Jardine, A.G. (2010) Effect of different classes of gadolinium-based contrast agents on control and nephrogenic systemic fibrosis-derived fibroblast proliferation. Radiology, 256 (3). pp. 735-743. ISSN 0033-8419 (doi:10.1148/radiol.10091131)

Edward, M., Quinn, J.A., Pasonen-Seppanen, S.M., McCann, B.A., and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162 (6). pp. 1224-1232. ISSN 0007-0963 (doi:10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103 (3). p. 401. ISSN 0007-0920 (doi:10.1038/sj.bjc.6605763)

2008

Edward, M., Quinn, J.A., Mukherjee, S., Jensen, M.B., Jardine, A.G., Mark, P., and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214 (5). pp. 584-593. ISSN 0022-3417 (doi:10.1002/path.2311)

2007

Amjad, S., Carachi, R., and Edward, M. (2007) Keratinocyte regulation of TGF-beta and connective tissue growth factor expression: A role in suppression of scar tissue formation. Wound Repair and Regeneration, 15 . pp. 748-755. (doi:10.1111/j.1524-475X.2007.00281.x)

Burden, A., Edward, M., Fitzgerald, L., Leman, J., and Thind, C. (2007) Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum. British Journal of Dermatology, 156 . pp. 473-479. (doi:10.1111/j.1365-2133.2006.07652.x)

2005

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2005) Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia. Molecular Cancer, 4 . (doi:10.1186/1476-4598-4-31)

Clayton, R.F., Edward, M., Kandyba, E.E., Klenerman, P., Patel, A.H., Rinaldi, A., and Willberg, C. (2005) Liver cell lines for the study of hepatocyte functions and immunological response. Liver International, 25 (2). pp. 389-402. ISSN 1478-3223 (doi:10.1111/j.1478-3231.2005.01017.x)

Edward, M., Gillan, C., Micha, D., and Tammi, R. (2005) Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis, 26 . pp. 1215-1223. (doi:10.1093/carcin/bgi064)

2003

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2003) The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression. Oncogene, 22 . pp. 7969-7980. (doi:10.1038/sj.onc.1206709)

2001

Brownbridge, G., Edward, M., Gold, J., and Mackie, R. (2001) Evaluation of the use of tyrosinase-specific and melanA/MART-1-specific reverse transcriptase-coupled-polymerase chain reaction to detect melanoma cells in peripheral blood samples from 299 patients with malignant melanoma. British Journal of Dermatology, 144 . pp. 279-287.

Edward, M. (2001) Melanoma cell-derived factors stimulate glycosaminoglycan synthesis by fibroblasts cultured as monolayers and within contracted collagen lattices. British Journal of Dermatology, 144 . pp. 465-470.

This list was generated on Sat Sep 20 21:04:39 2014 BST.
Jump to: Article
Number of items: 18.

Article

Nobis, M. et al. (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research, 73 (15). pp. 4674-4686. ISSN 0008-5472 (doi:10.1158/0008-5472.CAN-12-4545)

MacDonald, A.I. et al. (2012) A functional interaction between the MAGUK protein hDlg and the gap junction protein Connexin 43 in cervical tumour cells. Biochemical Journal, 446 (1). pp. 9-21. ISSN 0264-6021 (doi:10.1042/BJ20111144)

Pasonen-Seppänen, S., Takabe, P., Edward, M., Rauhala, L., Rilla, K., Tammi, M., and Tammi, R. (2012) Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling. Histochemistry and Cell Biology, 138 (6). pp. 895-911. ISSN 0948-6143 (doi:10.1007/s00418-012-1000-x)

Edward, M., Quinn, J.A., and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19 (3). pp. 379-386. ISSN 1067-1927 (doi:10.1111/j.1524-475X.2011.00678.x)

Katz, E., Verleyen, W., Blackmore, C.G., Edward, M., Smith, V.A., and Harrison, D.J. (2011) An analytical approach differentiates between individual and collective cancer invasion. Analytical Cellular Pathology, 34 (1-2). pp. 35-48. ISSN 2210-7177 (doi:10.3233/ACP-2011-0003)

Timpson, P. et al. (2011) Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Research, 71 (3). pp. 747-757. ISSN 0008-5472 (doi:10.1158/0008-5472.CAN-10-2267)

Edward, M., Quinn, J.A., Burden, A.D., Newton, B.B., and Jardine, A.G. (2010) Effect of different classes of gadolinium-based contrast agents on control and nephrogenic systemic fibrosis-derived fibroblast proliferation. Radiology, 256 (3). pp. 735-743. ISSN 0033-8419 (doi:10.1148/radiol.10091131)

Edward, M., Quinn, J.A., Pasonen-Seppanen, S.M., McCann, B.A., and Tammi, R.H. (2010) 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. British Journal of Dermatology, 162 (6). pp. 1224-1232. ISSN 0007-0963 (doi:10.1111/j.1365-2133.2010.09699.x)

Katz, E. et al. (2010) A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. British Journal of Cancer, 103 (3). p. 401. ISSN 0007-0920 (doi:10.1038/sj.bjc.6605763)

Edward, M., Quinn, J.A., Mukherjee, S., Jensen, M.B., Jardine, A.G., Mark, P., and Burden, A. (2008) Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. Journal of Pathology, 214 (5). pp. 584-593. ISSN 0022-3417 (doi:10.1002/path.2311)

Amjad, S., Carachi, R., and Edward, M. (2007) Keratinocyte regulation of TGF-beta and connective tissue growth factor expression: A role in suppression of scar tissue formation. Wound Repair and Regeneration, 15 . pp. 748-755. (doi:10.1111/j.1524-475X.2007.00281.x)

Burden, A., Edward, M., Fitzgerald, L., Leman, J., and Thind, C. (2007) Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum. British Journal of Dermatology, 156 . pp. 473-479. (doi:10.1111/j.1365-2133.2006.07652.x)

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2005) Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia. Molecular Cancer, 4 . (doi:10.1186/1476-4598-4-31)

Clayton, R.F., Edward, M., Kandyba, E.E., Klenerman, P., Patel, A.H., Rinaldi, A., and Willberg, C. (2005) Liver cell lines for the study of hepatocyte functions and immunological response. Liver International, 25 (2). pp. 389-402. ISSN 1478-3223 (doi:10.1111/j.1478-3231.2005.01017.x)

Edward, M., Gillan, C., Micha, D., and Tammi, R. (2005) Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis, 26 . pp. 1215-1223. (doi:10.1093/carcin/bgi064)

Aasen, T., Edward, M., Graham, S., and Hodgins, M. (2003) The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression. Oncogene, 22 . pp. 7969-7980. (doi:10.1038/sj.onc.1206709)

Brownbridge, G., Edward, M., Gold, J., and Mackie, R. (2001) Evaluation of the use of tyrosinase-specific and melanA/MART-1-specific reverse transcriptase-coupled-polymerase chain reaction to detect melanoma cells in peripheral blood samples from 299 patients with malignant melanoma. British Journal of Dermatology, 144 . pp. 279-287.

Edward, M. (2001) Melanoma cell-derived factors stimulate glycosaminoglycan synthesis by fibroblasts cultured as monolayers and within contracted collagen lattices. British Journal of Dermatology, 144 . pp. 465-470.

This list was generated on Sat Sep 20 21:04:39 2014 BST.

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Effect of 4-methylumbelliferone on hyaluronan synthesis by dermatomyositis and scleromyxedema-like dialysis patient fibroblasts within a living skin equivalent: potential mucinosis/fibrosis treatment
    British Skin Foundation
    2006 - 2007
     
  • Proof of Concept initiative: Replacing Animals with new tissue models for mechanism-based drug development in the post-genome era
    Scottish Enterprise
    2005 - 2006