Dr Jenifer Sassarini

  • Clinical Lecturer (Reproductive and Maternal Medicine)

telephone: 01412018613
email: Jenifer.Sassarini@glasgow.ac.uk

Research interests

Visit my Google Scholar page

My research interest is to develop a better understanding of the mechanism of hot flushing.  It is the commonest symptom experienced by menopausal women and it can have a significant impact on quality of life. It is also a common side effect of treatment in women with breast cancer and men with prostate cancer.  Indeed many women with breast cancer discontinue their endocrine therapy as a result of flushing, and this has an impact on breast cancer recurrence and mortality. 

HRT is an effective treatment for flushing, but is not suitable for all women, and there are many who are now reluctant to take it; an understanding of the mechanism is essential in developing alternative therapies.  We have used Laser Doppler Imaging with iontophoresis as a biomarker for hot flushing in healthy postmenopausal women and have conducted further studies to investigate potential treatments in healthy postmenopausal women.

We are currently aiming to develop projects investigating the mechanism and treatment of hot flushing in those with breast cancer.

Visit the Reproductive & Maternal Medicine Webpage

Publications

List by: Type | Date

Jump to: 2015 | 2013 | 2012 | 2011
Number of items: 7.

2015

Sassarini, J., and Lumsden, M. A. (2015) Oestrogen replacement in postmenopausal women. Age and Ageing, 44(4), pp. 551-558. (doi:10.1093/ageing/afv069) (PMID:26070875)

Sassarini, J., Lumsden, M. A., and Critchley, H. O.D. (2015) Sex hormone replacement in ovarian failure – new treatment concepts. Best Practice and Research: Clinical Endocrinology and Metabolism, 29(1), pp. 105-114. (doi:10.1016/j.beem.2014.09.010) (PMID:25617176)

Krishnadas, R. et al. (2015) Circulating Tumour Necrosis Factor is highly correlated with brainstem serotonin transporter availability in humans. Brain, Behavior, and Immunity, (doi:10.1016/j.bbi.2015.08.005) (Early Online Publication)

2013

Sassarini, J., and Lumsden, M.A. (2013) Non-hormonal management of vasomotor symptoms. Climacteric, 16(S1), pp. 31-36. (doi:10.3109/13697137.2013.805525)

Sassarini, J., Krishnadas, R., Cavanagh, J., Nicol, A., Pimlott, S. L., Ferrell, W., and Lumsden, M. A. (2013) Venlafaxine alters microvascular perfusion, [123I]beta-CIT binding and BDI scores in flushing postmenopausal women. Maturitas, 77(3), pp. 267-273. (doi:10.1016/j.maturitas.2013.12.003)

2012

Sassarini, J., Fox, H., Ferrell, W., Sattar, N., and Lumsden, M.A. (2012) Hot flushes, vascular reactivity and the role of the α-adrenergic system. Climacteric, 15(4), pp. 332-338. (doi:10.3109/13697137.2011.636847)

2011

Sassarini, J., Fox, H., Ferrell, W., Sattar, N., and Lumsden, M.A. (2011) Vascular function and cardiovascular risk factors in women with severe flushing. Clinical Endocrinology, 74(1), pp. 97-103. (doi:10.1111/j.1365-2265.2010.03921.x)

This list was generated on Tue Sep 1 21:18:13 2015 BST.
Jump to: Articles
Number of items: 7.

Articles

Sassarini, J., and Lumsden, M. A. (2015) Oestrogen replacement in postmenopausal women. Age and Ageing, 44(4), pp. 551-558. (doi:10.1093/ageing/afv069) (PMID:26070875)

Sassarini, J., Lumsden, M. A., and Critchley, H. O.D. (2015) Sex hormone replacement in ovarian failure – new treatment concepts. Best Practice and Research: Clinical Endocrinology and Metabolism, 29(1), pp. 105-114. (doi:10.1016/j.beem.2014.09.010) (PMID:25617176)

Krishnadas, R. et al. (2015) Circulating Tumour Necrosis Factor is highly correlated with brainstem serotonin transporter availability in humans. Brain, Behavior, and Immunity, (doi:10.1016/j.bbi.2015.08.005) (Early Online Publication)

Sassarini, J., and Lumsden, M.A. (2013) Non-hormonal management of vasomotor symptoms. Climacteric, 16(S1), pp. 31-36. (doi:10.3109/13697137.2013.805525)

Sassarini, J., Krishnadas, R., Cavanagh, J., Nicol, A., Pimlott, S. L., Ferrell, W., and Lumsden, M. A. (2013) Venlafaxine alters microvascular perfusion, [123I]beta-CIT binding and BDI scores in flushing postmenopausal women. Maturitas, 77(3), pp. 267-273. (doi:10.1016/j.maturitas.2013.12.003)

Sassarini, J., Fox, H., Ferrell, W., Sattar, N., and Lumsden, M.A. (2012) Hot flushes, vascular reactivity and the role of the α-adrenergic system. Climacteric, 15(4), pp. 332-338. (doi:10.3109/13697137.2011.636847)

Sassarini, J., Fox, H., Ferrell, W., Sattar, N., and Lumsden, M.A. (2011) Vascular function and cardiovascular risk factors in women with severe flushing. Clinical Endocrinology, 74(1), pp. 97-103. (doi:10.1111/j.1365-2265.2010.03921.x)

This list was generated on Tue Sep 1 21:18:13 2015 BST.