Dr Janet Gardner-Medwin

- Clinical Senior Lecturer (Clinical Specialties)
telephone: 01412010867
email: Janet.Gardner-Medwin@glasgow.ac.uk
Her research interests are the epidemiology of childhood rheumatological conditions, and the impact of chronic inflammatory conditions on normal childhood, adolescent development and beyond into adulthood.
2012
Hendry, G.J., Gardner-Medwin, J. , Steultjens, M.P., Woodburn, J., Sturrock, R. , and Turner, D.D. (2012) Frequent disconrdance between clinical and musculoskeletal ultrasound examinations of foot disease in juvenile idiopathic arthritis. Arthritis Care and Research, 64 (3). pp. 441-447. ISSN 2151-464X (doi:10.1002/acr.20655)
Hendry, G.J., Gardner-Medwin, J. , Steultjens, M.P.M., Woodburn, J., Sturrock, R.D. , and Turner, D.D. (2012) Frequent discordance between clinical and musculoskeletal ultrasound examinations of foot disease in juvenile idiopathic arthritis. Arthritis Care and Research, 64 (3). pp. 441-447. ISSN 2151-464X (doi:10.1002/acr.20655)
Watson, L. et al. (2012) Juvenile-onset SLE; disease activity, severity and damage - the UK JSLE Cohort Study. Arthritis and Rheumatism . ISSN 0004-3591 (doi:10.1002/art.34410) (In Press)
2011
Lal , S.D. et al. (2011) Agreement between proxy and adolescent assessment of disability, pain, and well-being in juvenile idiopathic arthritis. Journal of Pediatrics, 158, (2). pp. 307-312. ISSN 0022-3476 (doi:10.1016/j.jpeds.2010.08.003)
Martin, N, Krol, P., Smith, S., Murray, K., Pilkington, C.A., Davidson, J.E., Wedderburn, L.R., and Gardner-Medwin, J. [JD Research Group] (2011) A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies. Rheumatology, 50 (1). pp. 137-145. ISSN 1462-0324 (doi:10.1093/rheumatology/keq261)
2010
Hinks, A., Eyre, S., Ke, X., Barton, A., Martin, P., Flynn, E., Packham, J., Worthington, J., Thomson, W., and Gardner-Medwin, J. [CAPS and BSPAR study groups] (2010) Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis. Genes and Immunity, 11 (2). pp. 194-198. ISSN 1466-4879 (doi:10.1038/gene.2009.105)
Mandall , N.A. et al. (2010) Juvenile idiopathic arthritis (JIA): a screening study to measure class II skeletal pattern, TMJ PDS and use of systemic corticosteroids. Journal of Orthodontics, 37 (1). pp. 6-15. ISSN 1465-3125 (doi:10.1179/14653121042831)
Hinks , A., Martin , P., Flynn , E., Eyre , S., Packham , J., Barton , A., Worthington , J., Thomson , W., and Gardner-Medwin, J. [CAPS and BSPAR Study Groups] (2010) Association of the CCR5 gene with juvenile idiopathic arthritis. Genes and Immunity, 11 . pp. 584-589. (doi:10.1038/gene.2010.25)
Hyrich, K.L. et al. (2010) Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study. Rheumatology, 49 (1). pp. 116-122. ISSN 1462-0324 (doi:10.1093/rheumatology/kep352)
2009
Gunawardena, H. et al. (2009) Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis. Arthritis and Rheumatism, 60 (6). pp. 1807-1814. ISSN 0004-3591 (doi:10.1002/art.24547)
Gardner-Medwin, JM, Irwin, GJ , and Johnson, K (2009) MRI in Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis. Mri and Ultrasound in Diagnosis and Management of Rheumatological Diseases, 1154 . pp. 52-83.
2008
van der Hilst , J.C., Bodar , E.J., Barron , K.S., Frenkel , J., Drenth, J.P., van der Meer , J.W., Simon , A., and Gardner-Medwin, J. [International HIDS Study Group] (2008) Long-term follow-up, clinical features, and quality of life in a series of 103 patients with hyperimmunoglobulinemia D syndrome. Medicine, 87 (6). pp. 301-310. ISSN 1357-3039 (doi:10.1097/MD.0b013e318190cfb7)
Thornton, J et al. (2008) Costing juvenile idiopathic arthritis: examining patient-based costs during the first year after diagnosis. Rheumatology, 47 (7). pp. 985-990. ISSN 1462-0324 (doi:10.1093/rheumatology/ken039)
Adib , N., Hyrich , K., Thornton , J., Lunt, M., Davidson , J., Gardner-Medwin, J. , Foster , H., Baildam, E., Wedderburn , L., and Thomson , W. (2008) Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study. Rheumatology, 47 (7). pp. 991-995. ISSN 1462-0324
Adib, N., Hyrich, K., Thornton, J., Lunt, M., Davidson, J., Gardner-Medwin, J.M. , Foster, H., Baildam, E., Wedderburn, L., and Thomson, W. (2008) Association between duration of symptoms and severity of disease at first presentation to paediatric rheumatology: results from the Childhood Arthritis Prospective Study. Rheumatology, 47 (7). pp. 991-995. ISSN 1462-0324 (doi:10.1093/rheumatology/ken085)
Hendry, G., Gardner-Medwin, J. , Watt, G.F. , and Woodburn, J. (2008) A survey of foot problems in juvenile idiopathic arthritis. Musculoskeletal Care, 6 (4). pp. 221-232. (doi:10.1002/msc.134)
Wong, S., Macrae, V.E., Gracie, J.A. , McInnes, I. , Galea, P., Gardner-Medwin, J. , and Ahmed, S.F. (2008) Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis. Growth Hormone and IGF Research, 18 (5). pp. 369-378. ISSN 1096-6374 (doi:10.1016/j.ghir.2008.01.006)
2007
Macrae, VE, Wong, SC, Smith, W, Gracie, A, McInnes, I , Galea, P, Gardner-Medwin, J , Farquharson, C, Ahmed, SF , and Ahmed, SF (2007) Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis. Clinical Endocrinology, 67 . pp. 442-448. (doi:10.1111/j.1365-2265.2007.02908.x)
Piper, MK et al. (2007) Impaired endothelial function in systemic lupus erythematosus. Lupus, 16 . pp. 84-88. (doi:10.1177/0961203306074842)
2006
Gardner-Medwin, J. (2006) Rheumatoid factor polyarthritis. In: Szer, I.S., Kimura, P., Malleson, P. and Southwood, T. (eds.) Arthritis in Children and Adolescents: Juvenile Idiopathic Arthritis. Series: Oxford medical publications . Oxford University Press, Oxford, UK. ISBN 9780192632920
Gardner-Medwin, JM, Killeen, OG, Ryder, CAJ, Bradshaw, K, and Johnson, K (2006) Magnetic resonance imaging identifies features in clinically unaffected knees predicting extension of arthritis in children with monoarthritis. Journal of Rheumatology, 33 . pp. 2337-2343.
Killeen, OG, and Gardner-Medwin, JM (2006) In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy? Archives of Disease in Childhood, 91 (6). pp. 537-538. ISSN 0003-9888
2005
Gardner-Medwin, J., Galea, P., and Duncan, R. (2005) Muculoskeletal and connective tissue disorders. In: Beattie, J. and Carachi, R. (eds.) Practical Paediatric Problems: A textbook for MRCPCH. Hodder Arnold, London, UK. ISBN 9780340809327
2004
Neven, B et al. (2004) Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU. Blood, 103 . pp. 2809-2815. (doi:10.1182/blood-2003-07-2531)
2003
Black, APB, Bhayani, H, Ryder, CAJ, Pugh, MT, Gardner-Medwin, JMM , and Southwood, TR (2003) An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis. Arthritis Research and Therapy, 5 . R277-R284. (doi:10.1186/ar791)
Filer, AD, Gardner-Medwin, JM , Thambyrajah, J, Raza, K, Carruthers, DM, Stevens, RJ, Liu, L, Lowe, SE, Townend, JN, and Bacon, PA (2003) Diffuse endothelial dysfunction is common to ANCA associated systemic vasculitis and polyarteritis nodosa. Annals of the Rheumatic Diseases, 62 . pp. 162-167. ISSN 0003-4967
Johnson, K, Haigh, SF, Ehtisham, S, Ryder, C, and Gardner-medwin, J (2003) Childhood idiopathic chondrolysis of the hip: MRI features. Pediatric Radiology, 33 (3). pp. 194-199.
Wilkinson, N, Jackson, G, and Gardner-Medwin, J (2003) Biologic therapies for juvenile arthritis. Archives of Disease in Childhood, 88 . pp. 186-191. ISSN 0003-9888
2002
Black, APB, Bhayani, H, Ryder, CAJ, Gardner-Medwin, JMM , and Southwood, TR (2002) T-cell activation without proliferation in juvenile idiopathic arthritis. Arthritis Research, 4 . pp. 177-183.
Gardner-Medwin, JMM, Dolezalova, P, Cummins, C, and Southwood, TR (2002) Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet, 360 . pp. 1197-1202.
Johnson, K, and Gardner-Medwin, J (2002) Childhood arthritis: Classification and radiology. Clinical Radiology, 57 . pp. 47-58. (doi:10.1053/crad.2001.0732)
Johnson, K, Wittkop, B, Haigh, F, Ryder, C, and Gardner-Medwin, JM (2002) The early magnetic resonance imaging features of the knee in juvenile idiopathic arthritis. Clinical Radiology, 57 (6). pp. 466-471.
2001
Gardner-Medwin, JM, Macdonald, IA, Taylor, JY, Riley, PH, and Powell, RJ (2001) Seasonal differences in finger skin temperature and microvascular blood flow in healthy men and women are exaggerated in women with primary Raynaud's phenomenon. British Journal of Clinical Pharmacology, 52 . pp. 17-23.
2000
Njeh, C.F., Shaw, N., Gardner-Medwin, J.M. , Boivin, C.M., and Southwood, T.R. (2000) Use of quantitative ultrasound to assess bone status in children with juvenile idiopathic arthritis. Journal of Clinical Densitometry, 3 (3). pp. 251-260. ISSN 1094-6950 (doi:10.1385/JCD:3:3:251)
1997
Cockcroft, J.R., Noon, J.P., Gardner-Medwin, J. , and Bennett, T. (1997) Haemodynamic effects of adrenomedullin in human resistance and capacitance vessels. British Journal of Clinical Pharmacology, 44 (1). pp. 57-60. ISSN 0306-5251 (doi:10.1046/j.1365-2125.1997.00622.x)
Gardner-Medwin, J.M., Taylor, J.Y., Macdonald, I.A., and Powell, R.J. (1997) An investigation into variability in microvascular skin blood flow and the responses to transdermal delivery of acetylcholine at different sites in the forearm and hand. British Journal of Clinical Pharmacology, 43 (4). pp. 391-397. ISSN 0306-5251 (doi:10.1046/j.1365-2125.1997.00558.x)
Pallis, M., Lim, K., Gardner-Medwin, J.M. , Robins, R., and Powell, R. (1997) Correlation between CD29 density on CD8 + lymphocytes and serum IgG in systemic lupus erythematosus. Lupus, 6 (4). pp. 379-384. ISSN 0961-2033 (doi:10.1177/096120339700600406)
1996
Gardner-Medwin, J.M., and Powell, R.J. (1996) One patient, two unusual conditions and three basic lessons. Annals of the Rheumatic Diseases, 55 (6). pp. 350-352. ISSN 0003-4967 (doi:10.1136/ard.55.6.350)
1994
Gardner-Medwin, J.M., Smith, N.J., and Powell, R.J. (1994) Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy. Annals of the Rheumatic Diseases, 53 (12). pp. 828-832. ISSN 0003-4967
Powell, R.J., and Gardner-Medwin, J.M. (1994) Guideline for the clinical use and dispensing of thalidomide. Postgraduate Medical Journal, 70 (830). pp. 901-904. ISSN 0032-5473
Gardner-Medwin, J.M., Lim, K.L., and Powell, R.J. (1994) Fever as an unusual presentation of a common condition. Annals of the Rheumatic Diseases, 53 (11). pp. 711-713. ISSN 0003-4967
Gardner-Medwin, J.M., and Powell, R.J. (1994) Thalidomide--the way forward. Postgraduate Medical Journal, 70 (830). pp. 860-862. ISSN 0032-5473
Hopkinson, N.P., Lim, K., and Gardner-Medwin, J.M. (1994) Antiphospholipid antibodies (aPL) in systemic lupus erythematosus. Are they specific tools for the diagnosis of aPL syndrome? Annals of the Rheumatic Diseases, 53 (9). pp. 619-620. ISSN 0003-4967
1989
Gardner-Medwin, J.M., Sayer, J., Mahida, Y.R., and Spiller, R.C. (1989) Spontaneous rupture of spleen following streptokinase therapy. Lancet, 334 (8676). p. 1398. ISSN 0140-6736 (doi:10.1016/S0140-6736(89)92009-6)
- A pilot study to investigate the microbiota profile and metabolic activity in the colon of juvenile idiopathic arthritis patients at risk of developing Crohn's disease
Yorkhill Children's Foundation
2011 - 2012
- Study of the prevalence of musculoskeletal abnormalities, particularly arthiritis, in children with Down's syndrome
Arthritis Research UK
2011 - 2011
- Equipment grant - Siemens Acuson Sequoia 512 ultrasound machine
Arthritis Research UK
2008 - 2009
- Foot disease in juvenile idiopathic arthritis: a Randomised Controlled Trial (RCT) of an intensive foot care programme
Arthritis Research UK
2007 - 2010
- Evidence of risk for the development of premature cardiovascular disease in juvenile idiopathic arthritis?
Scottish Executive Health Department
2007 - 2010
- ARC Integrated Clinical Arthritis Centre Grant (ICAC)
Arthritis Research UK
2007 - 2008
- The early identification of disease progression and disease relapse in Juvenile Idiopathic Arthritis (JIA)
Arthritis Research UK
2006 - 2006
- Childhood arthritis prospective study
Arthritis Research UK
2004 - 2010
- Senior Lecturer in Paediatric Rheumatology
Arthritis Research UK
2002 - 2009
