Dr James Boyle

  • Honorary Clinical Associate Professor (Medicine)
  • Associate Academic (Cardiovascular and Medical Sciences)

Biography

James Boyle is a Consultant Endocrinologist based at Glasgow Royal Infirmary. He graduated from the University of Dundee and trained in Endocrinology in Glasgow. He completed an MD at the University of Glasgow in the Henry Wellcome Laboratory of Cell Biology examining the effect of metformin on vascular function and AMP-activated protein kinase (AMPK) in Type 2 Diabetes. Diabetes UK awarded this work with the Type 2 Diabetes Research Award. He was recently awarded a NRS Career Research Fellowship by the Chief Scientist Office to continue his interest in translational diabetes research.  Dr Boyle is Director of MBChB3 and Honorary Clinical Associate Professor at the School of Medicine, University of Glasgow. Dr Boyle is a Fellow of the Royal College of Physicians in Glasgow.

Research interests

1. Translational studies aimed at understanding the mechanisms of insulin signalling/glucose transport in human tissues and improving the health of those with diabetes

- SNARE protein function and regulation in GLUT4 membrane trafficking

- AMP-activated protein kinase in the regulation of metabolism.

2. Medical Education

- Dr Boyle has completed an MSc in Health Professions Education at the University of Glasgow investigating a novel pedagogical approach to teaching diabetes to medical undergraduates.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Type 2 diabetes research award prize
    Diabetes UK
    2008 - 2008
     
  • Studies of Extra-Adrenal Aldosterone Activity
    Wellcome Trust
    2004 - 2005
     
  • The effects of metformin on vascular function and adipocyte AMPK activation in type 2 diabetes
    British Heart Foundation
    2004 - 2006
     

Teaching

2016 – Present
Director of MBChB3, Undergraduate Medical School, University of Glasgow

2014 – Present
Medicine Lead for the Clinical Years, Undergraduate Medical School, University of Glasgow

2014 – Present
Host of 'Diabetes Acute Care Day' for medical undergraduates

2013 – Present
Host of Special Selected Component entitled 'An Introduction to Research in Medical Education' for medical undergraduates

2012 – Present
External Examiner for MSc Diabetes Care and Management, Glasgow Caledonian University

2010 – 2013
Undergraduate Sub Dean, School of Medicine, University of Glasgow

Publications

List by: Type | Date

Jump to: 2016 | 2015 | 2014 | 2012 | 2011 | 2010 | 2008 | 2007 | 2003
Number of items: 14.

2016

Boyle, J.G., Quail, N., Loo, X.Y., and Linn, A. (2016) The flipped classroom - is it worth the bother? Clinical Teacher, (In Press)

MacEwen, A.W., Carty, D.M., McConnachie, A., McKay, G.A., and Boyle, J.G. (2016) A "Diabetes Acute Care Day" for medical students increases their knowledge and confidence of diabetes care: a pilot study. BMC Medical Education, 16, p. 88. (doi:10.1186/s12909-016-0600-x) (PMID:26956764) (PMCID:PMC4784451)

2015

Petrie, M.C., Boyle, J.C., and McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32(7), pp. 981-982. (doi:10.1111/dme.12709) (PMID:25645049)

Livingstone, R., and Boyle, J. (2015) Improving the quality of assessment and management of hypoglycaemia in hospitalised patients with diabetes mellitus by introducing 'hypo boxes' to general medical wards with a specialist interest in diabetes. BMJ Quality Improvement Reports, 4(1), u207686.w3. (doi:10.1136/bmjquality.u207686.w3067)

2014

Boyle, K. R., Boyle, J. G., Fisher, M., and McKay, G. (2014) Olanzapine. Practical Diabetes, 31(7), 304-305a. (doi:10.1002/pdi.1891)

2012

McKay, G.A., and Boyle, J.G. (2012) Patient education on the benefit and risks of medications goes beyond metformin. Diabetic Medicine, 29(11), pp. 1471-1472. (doi:10.1111/j.1464-5491.2012.03754.x) (PMID:22817327)

2011

Combet, E., Lean, M.E.J., Boyle, J., Crozier, A., and Davidson, D.F. (2011) Dietary flavonols contribute to false-positive elevation of homovanillic acid, a marker of catecholamine-secreting tumours. Clinica Chimica Acta, 412(1-2), pp. 165-169. (doi:10.1016/j.cca.2010.09.037)

Boyle, J.G., Logan, P.J., Jones, G.C., Small, M., Sattar, N., Connell, J.M.C., Cleland, S.J., and Salt, I.P. (2011) AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study. Diabetologia, 54(7), pp. 1799-1809. (doi:10.1007/s00125-011-2126-4)

2010

Boyle, J.G., Salt, I.P., and McKay, G.A. (2010) Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target. Diabetic Medicine, 27(10), pp. 1097-1106. (doi:10.1111/j.1464-5491.2010.03098.x) (PMID:20854376)

Boyle, J. G., McKay, G. A., and Fisher, M. (2010) Drugs for diabetes: part 1 metformin. British Journal of Cardiology, 17(5), pp. 231-234.

Boyle, J., and Fisher, M. (2010) The addition of insulin to metformin and sulphonylureas: results of the 4-T study. Practical Diabetes International, 27(1), pp. 5-6. (doi:10.1002/pdi.1427) (PMID:9521121) (PMCID:PMC2143916)

2008

Boyle, J. G., Logan, P. J., Ewart, M.-A., Reihill, J. A., Ritchie, S. A., Connell, J. M.C., Cleland, S. J., and Salt, I. P. (2008) Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. Journal of Biological Chemistry, 283(17), pp. 11210-11217. (doi:10.1074/jbc.M710048200)

2007

Boyle, J.G., Davidson, D.F., Perry, C.G., and Connell, J. (2007) Comparison of diagnostic accuracy of urinary free metanephrines, vanillyl mandelic acid, and catecholamines and plasma catecholamines for diagnosis of pheochromocytoma. Journal of Clinical Endocrinology and Metabolism, 92(12), pp. 4602-4608.

2003

Stirling, C., Houston, J., Robertson, S., Boyle, J.G., Allan, A., Norrie, J., and Isles, C. (2003) Diarrhoea, vomiting and ACE inhibitors: – an important cause of acute renal failure. Journal of Human Hypertension, 17(6), pp. 419-423. (doi:10.1038/sj.jhh.1001571) (PMID:12764405)

This list was generated on Sun May 1 22:15:26 2016 BST.
Jump to: Articles
Number of items: 14.

Articles

Boyle, J.G., Quail, N., Loo, X.Y., and Linn, A. (2016) The flipped classroom - is it worth the bother? Clinical Teacher, (In Press)

MacEwen, A.W., Carty, D.M., McConnachie, A., McKay, G.A., and Boyle, J.G. (2016) A "Diabetes Acute Care Day" for medical students increases their knowledge and confidence of diabetes care: a pilot study. BMC Medical Education, 16, p. 88. (doi:10.1186/s12909-016-0600-x) (PMID:26956764) (PMCID:PMC4784451)

Petrie, M.C., Boyle, J.C., and McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32(7), pp. 981-982. (doi:10.1111/dme.12709) (PMID:25645049)

Livingstone, R., and Boyle, J. (2015) Improving the quality of assessment and management of hypoglycaemia in hospitalised patients with diabetes mellitus by introducing 'hypo boxes' to general medical wards with a specialist interest in diabetes. BMJ Quality Improvement Reports, 4(1), u207686.w3. (doi:10.1136/bmjquality.u207686.w3067)

Boyle, K. R., Boyle, J. G., Fisher, M., and McKay, G. (2014) Olanzapine. Practical Diabetes, 31(7), 304-305a. (doi:10.1002/pdi.1891)

McKay, G.A., and Boyle, J.G. (2012) Patient education on the benefit and risks of medications goes beyond metformin. Diabetic Medicine, 29(11), pp. 1471-1472. (doi:10.1111/j.1464-5491.2012.03754.x) (PMID:22817327)

Combet, E., Lean, M.E.J., Boyle, J., Crozier, A., and Davidson, D.F. (2011) Dietary flavonols contribute to false-positive elevation of homovanillic acid, a marker of catecholamine-secreting tumours. Clinica Chimica Acta, 412(1-2), pp. 165-169. (doi:10.1016/j.cca.2010.09.037)

Boyle, J.G., Logan, P.J., Jones, G.C., Small, M., Sattar, N., Connell, J.M.C., Cleland, S.J., and Salt, I.P. (2011) AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study. Diabetologia, 54(7), pp. 1799-1809. (doi:10.1007/s00125-011-2126-4)

Boyle, J.G., Salt, I.P., and McKay, G.A. (2010) Metformin action on AMP-activated protein kinase: a translational research approach to understanding a potential new therapeutic target. Diabetic Medicine, 27(10), pp. 1097-1106. (doi:10.1111/j.1464-5491.2010.03098.x) (PMID:20854376)

Boyle, J. G., McKay, G. A., and Fisher, M. (2010) Drugs for diabetes: part 1 metformin. British Journal of Cardiology, 17(5), pp. 231-234.

Boyle, J., and Fisher, M. (2010) The addition of insulin to metformin and sulphonylureas: results of the 4-T study. Practical Diabetes International, 27(1), pp. 5-6. (doi:10.1002/pdi.1427) (PMID:9521121) (PMCID:PMC2143916)

Boyle, J. G., Logan, P. J., Ewart, M.-A., Reihill, J. A., Ritchie, S. A., Connell, J. M.C., Cleland, S. J., and Salt, I. P. (2008) Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. Journal of Biological Chemistry, 283(17), pp. 11210-11217. (doi:10.1074/jbc.M710048200)

Boyle, J.G., Davidson, D.F., Perry, C.G., and Connell, J. (2007) Comparison of diagnostic accuracy of urinary free metanephrines, vanillyl mandelic acid, and catecholamines and plasma catecholamines for diagnosis of pheochromocytoma. Journal of Clinical Endocrinology and Metabolism, 92(12), pp. 4602-4608.

Stirling, C., Houston, J., Robertson, S., Boyle, J.G., Allan, A., Norrie, J., and Isles, C. (2003) Diarrhoea, vomiting and ACE inhibitors: – an important cause of acute renal failure. Journal of Human Hypertension, 17(6), pp. 419-423. (doi:10.1038/sj.jhh.1001571) (PMID:12764405)

This list was generated on Sun May 1 22:15:26 2016 BST.