Research Interests

Research interests include clinical and genetic aspects of psoriasis.

Selected Recent Publications

CS Jury, P McHenry, AD Burden, R Lever, D Bilsland.
Narrowband ultraviolet B (UVB) phototherapy in children
Clin Exp Dermatol 2006 31 196 - 199
Abstract

E Campalani, MH Allen, D Fairhurst, HS Young, CO Menonca, AD Burden, CEM Griffiths, MA Crook, JNWN Barker, CH Smith.
Apolipoprotein E gene polymorphisms are associated with psoriasis but do not determine disease response to acitretin
Br J Dermatol 2006 154 345-352
Abstract

CH Smith, AV Anstey, JNWN Barker, AD Burden, RJG Chalmers, D Chandler AY Finlay, CEM Griffiths K Jackson, NJ McHugh, KE McKenna, N Reynolds, AD Ormerod
British Association of Dermatologists Guidelines for the use of biological interventions in psoriasis 2005
Br J Dermatol 2005 153 486 - 489
Abstract

C Stover, S Barrett, N Lynch, JNWN Barker, D Burden, R Trembath, W Schwaeble, C Veal
Functional MASP2 single nucleotide polymorphism plays no role in psoriasis.
Br J Dermatol 2005 1313-1315

G Abecasis, M Allen, JNWN Barker, D Burden, F Capon, E Christophers, JT Elder, J Fischer, E Giardina, JE Gudjonsson, U Hüffmeier, S Jenisch,
A Karason, J Kere, RP Nair, G Novelli, ZS. Qin, L Samuelsson, F Sanchez, M Stahle-Backdahl, P Stuart, D Tillman, H Traupe, R Trembath, H Valdimarsson, C Veal, JJ Voorhees, M Weichenthal,
Fine Mapping of the Psoriasis Susceptibility Gene PSORS1: A Reassessment of Risk Associated With a Putative Risk Haplotype Lacking HLA Cw6
J Invest Dermatol 2005 124 921-930

A MacDonald, AD Burden.
Non-invasive monitoring for methotrexate hepatotoxicity
Br J Dermatol 2005 152 405-408
Abstract

MH Allen, H Ameen, C Veal, J Evans, VS Ramrakha-Jones, AM Marsland, AD Burden, CEM Griffiths, RC Trembath, JNWN Barker
The major psoriasis susceptibility locus PSORS1 is not a risk factor for late onset psoriasis
J Invest Dermatol 2005 124 103-107
Abstract

F Capon, P Hobby, MH Allen, AD Burden, D Tillman, JN Barker, RC Trembath.
A synonymous SNP of the corneodesmosin gene leads to increased mRNA tability and demonstrates association with psoriasis across diverse ethnic groups
Hum Mol Genet 2004 13 2361-2368
Abstract

Capon F, Helms C, Veal CD, Tillman D, Burden AD, Barker JN, Bowcock AM, Trembath RC.
Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis.
J Med Genet. 2004 Jun;41(6):459-460.
Abstract

Tang X, Boxer M, Drummond A, Ogston P, Hodgins M, Burden AD.
A germline mutation in KIT in familial diffuse cutaneous mastocytosis.
J Med Genet. 2004 Jun;41(6):E88.
Abstract

The International Psoriasis Genetics Consortium.
The International Psoriasis Genetics Study: Assessing Linkage to 14
Candidate Susceptibility Loci in a Cohort of 942 Affected Sib Pairs.
Am. J. Hum. Genet. 73:430–437, 2003
No Abstract available.

Capon F, Toal IK, Evans JC, Allen MH, Patel S, Tillman D, Burden D, Barker JN, Trembath RC.
Haplotype analysis of distantly related populations implicates corneodesmosin in psoriasis susceptibility.
J Med Genet. 2003 Jun;40(6):447-52.
Abstract

Asumalahti K, Ameen M, Suomela S, Hagforsen E, Michaelsson G, Evans J, Munro M, Veal C, Allen M, Leman J, David Burden A, Kirby B, Connolly M, Griffiths CE, Trembath RC, Kere J, Saarialho-Kere U, Barker JN.
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.
J Invest Dermatol. 2003 Apr;120(4):627-32.
Abstract

Veal CD, Capon F, Allen MH, Heath EK, Evans JC, Jones A, Patel S, Burden D, Tillman D, Barker JN, Trembath RC.
Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus.
Am J Hum Genet. 2002 Sep;71(3):554-64. Epub 2002 Jul 29.
Abstract

Bhushan M, Burden AD, McElhone K, James R, Vanhoutte FP, Griffiths CE.
Oral liarozole in the treatment of palmoplantar pustular psoriasis: a randomized, double-blind, placebo-controlled study.
Br J Dermatol. 2001 Oct;145(4):546-53.
Abstract

Leman J, Burden D.
Psoriasis in children: a guide to its diagnosis and management.
Paediatric Drugs. 2001;3(9):673-80.
Abstract

Veal CD, Clough RL, Barber RC, Mason S, Tillman D, Ferry B, Jones AB, Ameen M, Balendran N, Powis SH, Burden AD, Barker JN, Trembath RC
Identification of a novel psoriasis susceptibility locus at 1p and evidence of epistasis between PSORS1 and candidate loci.
J Med Genet. 2001 Jan;38(1):7-13.
Abstract

Burden AD
Identifying a gene for psoriasis on chromosome 6 (Psors1)
Br J Dermatol. 2000 Aug;143(2):238-41.
No abstract available

Burden AD, Krafchik BR
Subcutaneous fat necrosis of the newborn: a review of 11 cases.
Pediatr Dermatol. 1999 Sep-Oct;16(5):384-7. Review.
Abstract

Burden AD
Management of psoriasis in childhood.
Clin Exp Dermatol. 1999 Sep;24(5):341-5. Review.
Abstract

Burden AD, Newell J, Andrew N, Kavanagh G, Connor JM, MacKie RM
Genetic and environmental influences in the development of multiple primary melanoma.
Arch Dermatol 1999 Mar;135(3):261-5
Abstract

Burden AD, Javed S, Bailey M, Hodgins M, Connor M, Tillman D
Genetics of psoriasis: paternal inheritance and a locus on chromosome 6p.
J Invest Dermatol 1998 Jun;110(6):958-60
Abstract

Filaggrin null alleles are not associated with psoriasis
J Invest Dermatol 2007 127 1878-82

SK Siddha  and AD Burden
Recognition and treatment of psoriasis in children
Paediatrics and Child Health 2007 17 390- 394

F Capon, P Di Meglio, J Szaub, C Dunster, NJ Prescott, C Dunster, L Baumber, K Timms, A Gutin, V Abkevic, AD Burden, J Lanchbury, JN Barker, RC Trembath, FO Nestle.
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.
Human Genetics 2007 122 201-206

A MacDonald, AD Burden. Psoriasis: advances in pathophysiology and management
Postgrad Med J  2007 83  690 - 697

A Sergeant, A Makrygeorgou, WC Chan, A Thorrat, AD Burden. C-reactive protein in psoriasis.
Br J Dermatol 2008 158 217-219

N Wolf, M Quaranta, NJ Prescott, M Allen, R Smith, AD Burden, J Worthington, CE Griffiths, CG Mathew, JN Barker, F Capon, RC Trembath
Psoriasis is associated with pleiotropic susceptibility loci identified in Type 2 Diabetes and Crohn’s disease
J Med Genet            2008 45 114-6

M Edward, J Quinn, S Bhattacharya, M Britt-Jensen, AG Jardine, P Mark, AD Burden.
MRI contrast agent ‘activates’ fibroblasts: a possible cause of nephrogenic systemic fibrosis
Journal of Pathology  2008 214 584 - 593

F Capon, MJ Bijlmakers, N Wolf, M Quaranta, U Huffmeier, M Allen, K Timms, V Abkevich, A Gutin, R Smith, J Worthington, AD Burden, CEM Griffiths, A Hayday, FO Nestle, A Reis, J Lanchbury, J N Barker, R C Trembath
Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene
Human Molecular Genetics  2008 17 1938-45

GBE Jemec, C Ganslandt,  J-P Ortonne, Y Poulin, AD Burden, P de Unamuno, B Berne, A Figueiredo, J Austad.
A new scalp formulation of calcipotriene plus betamethasone compared with its active ingredients and the vehicle in the treatment of scalp psoriasis: a randomized, double-blind, controlled trial
J Am Acad Dermatol 2008 59 455 - 463

JA Leman, AD Burden
Treatment of moderate to severe plaque psoriasis with infliximab Therapeutics and Clinical Risk Management  2008 4 1165-76

F Al-Niaimi, C Clark, A Thorrat, AD Burden
Idiopathic lobular panniculitis: remission induced and maintained with infliximab
Br J Dermatol 2009 161 691 - 692

Department of Dermatology
Western Infirmary
Glasgow

David.Burden@glasgow.ac.uk