An Image-based approach to reveal the poromechanics behaviour of soft tissues

Dr Olga Barrera (Oxford Brookes University)

Friday 30th September, 2022 14:00-15:00 Maths 311B / ZOOM (ID: 820 7466 7233)

Abstract

Soft tissues consist of hierarchical porous architectures which vary depending on the role they play. Understanding the relationship between the architectural parameters and the mechanical properties is the key to the design of biomimetic synthetic tissues. My talk focuses on recent finding related to the knee meniscus which is seen as an optimized-by-nature load bearing and damper system. The tissue is a functionally graded material, the time dependent behavior is dictated by the fluid flow inside the pores which is modelled, in a poroelastic framework, through a fractional pore pressure diffusion equation. Advances in imaging at different scale, mechanical and poromechanics testing, material model selection, machine learning and numerical schemes will be presented.

References:
[1] Barrera, O. Comput Mech 68, 1267–1282 (2021). https://doi.org/10.1007/s00466-021-02067-5.
[2] Maritz, J. et al. Ann Biomed Eng 49, 2421–2429 (2021). https://doi.org/10.1007/s10439-021-02792-1.
[3] Agustoni, G. et al. Ann Biomed Eng 49, 2273–2281 (2021). https://doi.org/10.1007/s10439-021-02763-6.
[4] Bulle, R. et al. Appl. Sci. 2021, 11, 9405. https://doi.org/10.3390/app11209405.

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