The mechanics of cell migration

Davide Ambrosi (Politecnico di Torino)

Thursday 7th November, 2019 14:00-15:00 Maths 311B

Abstract

Cell migration is a very attractive mechanobiological system for
mathematical modelling. The reason of such a fascination resides in the
challenging contrast between the simplicity of the basic ingredients of
the system (two phases that exchange mass), versus the rich observed
dynamics: steady and pulsatile motion, excitability, polarization,
material reorganization, transition between rest and excited states. In
this talk I will provide examples of mathematical questions that stem when
modelling a migrating cell as mechanical system, obeying balance laws. In
some cases energetic arguments can support a purely mechanical explanation
for the observed behavior.

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