Breadcrumbs

Dr Christopher Quince

Profile
Publications

Reader (Infrastructure and Environment)

email: Christopher.Quince@glasgow.ac.uk

Research interests

Applications of Birth-and-death Processes to Ecology and Population Genetics

The theory of birth-and-death processes forms a natural framework for describing processes that operate on the level of individuals in Ecology and Population Genetics. In collaboration with Todd Parsons from the Mathematics department of the University of Toronto, I have been studying an application of this framework to f ixation in haploid populations experiencing density dependent population dynamics (Parsons and Quince I and II 2007). We approximated the discrete stochastic system with a continuous Fokker-Planck equation and then derived asymptotic analytic solutions to this equation. We then compared these approximate solutions with exact numerical solutions of the original discrete system. This process yielded valuable insights into the fixation of alleles in populations changing deterministically in size and fluctuating about equilibriums due to demographic stochasticity. In future we aim to extend this work to consider the long term interaction of genetics and demographics in haploid populations.

There is a direct mathematical connection between the dynamics of alleles in haploid populations and the clonal population dynamics of microbial organisms. I aim to exploit this connection in my current position using techniques from Population Genetics to develop a mathematical and computational framework for the description of microbial communities.

Optimal Models of Growth in Fish

The other major focus of my research is life history strategies and in particular models of optimal resource allocation between growth and reproduction in seasonally reproducing fish. For this research I focused on lake trout (Salvelinus namaycush), a species which shows substantial life history variation and for which we have good quality growth and maturation data. I derived a growth model based on optimal resource allocation and determined, using Bayesian statistics, the extent to which the model assumptions are supported by hatchery data on individual growth and compared fitted parameters across wild populations.

Coevolution in Communities of Interacting Species

The majority of my published research has focused on food web models of community coevolution. I used simulations of these models to study the structure, resistance to perturbation and relationship between ecological role and evolutionary history in food web communities.

Link to personal webpage

http://userweb.eng.gla.ac.uk/christopher.quince/

List all by: Type | Date

Jump to: 2012 | 2011 | 2010 | 2009 | 2008

Number of items: 17.

2012

Logares, R., Haverkamp, T., Kumar, S., Lanzén, A., Nederbragt, A., Quince, C., and Kauserud, H. (2012) Environmental microbiology through the lens of high-throughput DNA sequencing: synopsis of current platforms and bioinformatics approaches. Journal of Microbiological Methods, 91 (1). pp. 106-113. ISSN 0167-7012 (doi:10.1016/j.mimet.2012.07.017)

Fonseca, V.G., Nichols, B., Lallias, D., Quince, C., Carvalho, G.R., Power, D.M., and Creer, S. (2012) Sample richness and genetic diversity as drivers of chimera formation in nSSU metagenetic analyses. Nucleic Acids Research, 40 (9). e66. ISSN 0305-1048 (doi:10.1093/nar/gks002)

Gobet, A., Böer, S.I., Huse, S.M., van Beusekom, J.E.E., Quince, C., Sogin, M.L., Boetius, A., and Ramette, A. (2012) Diversity and dynamics of rare and of resident bacterial populations in coastal sands. ISME Journal, 6 (3). pp. 542-553. ISSN 1751-7362 (doi:10.1038/ismej.2011.132)

Vos, M., Quince, C., Pijl, A.S., de Hollander, M., and Kowalchuk, G.A. (2012) A comparison of rpoB and 16S rRNA as markers in pyrosequencing studies of bacterial diversity. PLoS ONE, 7 (2). e30600. ISSN 1932-6203 (doi:10.1371/journal.pone.0030600)

2011

Hartmann, M. et al. (2011) V-REVCOMP: automated high-throughput detection of reverse complementary 16S rRNA gene sequences in large environmental and taxonomic datasets. FEMS Microbiology Letters, 319 (2). pp. 140-145. ISSN 0378-1097 (doi:10.1111/j.1574-6968.2011.02274.x)

Quince, C., Lanzen, A., Davenport, R.J., and Turnbaugh, P.J. (2011) Removing noise from pyrosequenced amplicons. BMC Bioinformatics, 12 (1). p. 38. ISSN 1471-2105 (doi:10.1186/1471-2105-12-38)

Edgar, R.C., Haas, B.J., Clemente, J.C., Quince, C., and Knight, R. (2011) UCHIME improves sensitivity and speed of chimera detection. Bioinformatics, 27 (16). pp. 2194-2200. ISSN 1367-4803 (doi:10.1093/bioinformatics/btr381)

Gubry-Rangin, C., Hai, B., Quince, C., Engel, M., Thomson, B.C., James, P., Schloter, M., Griffiths, R.I., Prosser, J.I., and Nicoll, G.W. (2011) Niche specialization of terrestrial archaeal ammonia oxidizers. Proceedings of the National Academy of Sciences of the United States of America, 108 (52). pp. 21206-21211. ISSN 0027-8424 (doi:10.1073/pnas.1109000108)

Haig, S.J., Collins, G., Davies, R.L., Dorea, C.C., and Quince, C. (2011) Biological aspects of slow sand filtration: past, present and future. Water Science and Technology: Water Supply, 11 (4). p. 468. ISSN 1606-9749 (doi:10.2166/ws.2011.076)

2010

Gobet, A., Quince, C., and Ramette, A. (2010) Multivariate Cutoff Level Analysis (MultiCoLA) of large community data sets. Nucleic Acids Research, 38 (15). e155. ISSN 0305-1048 (doi:10.1093/nar/gkq545)

Parsons, T. L., Quince, C., and Plotkin, J. B. (2010) Some Consequences of Demographic Stochasticity in Population Genetics. Genetics, 185 (4). pp. 1345-1354. ISSN 0016-6731 (doi:10.1534/genetics.110.115030)

Turnbaugh, P. J. et al. (2010) Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins. Proceedings of the National Academy of Sciences, 107 (16). pp. 7503-7508. ISSN 0027-8424 (doi:10.1073/pnas.1002355107)

Wang, G. P., Sherrill-Mix, S. A., Chang, K. M., Quince, C., and Bushman, F. D. (2010) Hepatitis C Virus Transmission Bottlenecks Analyzed by Deep Sequencing. Journal of Virology, 84 (12). pp. 6218-6228. ISSN 0022-538X (doi:10.1128/JVI.02271-09)

2009

Quince, C., Lanzen, A., Curtis, T.P., Davenport, R.J., Hall, N., Head, I.M., Read, F., and Sloan, W.T. (2009) Accurate determination of microbial diversity from 454 pyrosequencing data. Nature Methods, 6 (9). 639-U27. ISSN 1548-7091 (doi:10.1038/NMETH.1361 )

2008

Quince, C., Abrams, P.A., Shuter, B.J., and Lester, N.P. (2008) Biphasic growth in fish I: Theoretical foundations. Journal of Theoretical Biology, 254 (2). pp. 197-206. ISSN 0022-5193 (doi:10.1016/j.jtbi.2008.05.029)

Quince, C., Shuter, B.J., Abrams, P.A., and Lester, N.P. (2008) Biphasic growth in fish II: Empirical assessment. Journal of Theoretical Biology, 254 (2). pp. 207-214. ISSN 0022-5193 (doi:10.1016/j.jtbi.2008.05.030)

Sloan, W.T., Quince, C., and Curtis, T.P. (2008) The uncountables. In: Zengler, K. (ed.) Accessing Uncultivated Microorganisms: From the Environment to Organisms and Genomes and Back. ASM Press, Washington DC, USA. ISBN 9781555814069

This list was generated on Wed Jun 19 14:24:55 2013 BST.

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