Dental School

Dr Shauna Culshaw

  • Senior Clinical Research Fellow (Dental School)
  • Associate Academic (Institute of Infection Immunity and Inflammation)

email: Shauna.Culshaw@glasgow.ac.uk


Biography

Shauna Culshaw graduated from The University of Glasgow with a B.Sc. (Hons) in Immunology in 1999, and received a PhD in Immunology in 2003. These were undertaken as 'intercalated' degrees, after which clinical training was completed, and she graduated in Dentistry in 2005, and was awarded MFDS (Glasgow) in 2007, before being appointed in August 2007 as Clinical Lecturer, Honorary SpR at Glasgow Dental Hospital.


Research interests

The host immune response is instrumental in determining the outcome of infectious and inflammatory disease, and the regulation of this response is the main focus of Dr Culshaw's research. Dr Culshaw's PhD was awarded for studies of interleukin 18 in inflammation and infection. During the summer vacations of 2003 and 2004, she worked as a visiting scientist at The Forsyth Institute, Boston, working on a vaccine to protect against dental caries.

This work sparked a current collaborative project with The University of Strathclyde, dissecting the immune response to mutans streptococci in the oral cavity. Strong research links are also maintained with The University of Glasgow Biomedical Research Centre, providing a world class environment for future investigation of inflammatory disease.

Jump to: 2012 | 2011 | 2010 | 2008 | 2007 | 2005 | 2004 | 2003 | 2001
Number of items: 12.

2012

Farquharson, D., Butcher, J.P. , and Culshaw, S. (2012) Periodontitis, porphyromonas, and the pathogenesis of rheumatoid arthritis. Mucosal Immunology, 5 (2). pp. 112-120. ISSN 1933-0219 (doi:10.1038/mi.2011.66)

2011

Butcher, J.P., Malcolm, J., Benson, R.A. , Deng, D.M., Brewer, J.M. , Garside, P. , and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90 (10). pp. 1221-1227. ISSN 0022-0345 (doi:10.1177/0022034511412970)

Culshaw, S., McInnes, I.B. , and Liew, F.Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38 . pp. 106-113. ISSN 0303-6979 (doi:10.1111/j.1600-051X.2010.01669.x)

2010

Ramage, G., Culshaw, S. , Jones, B., and Williams, C. (2010) Are we any closer to beating the biofilm: novel methods of biofilm control. Current Opinion in Infectious Diseases, 23 (6). pp. 560-566. ISSN 0951-7375 (doi:10.1097/QCO.0b013e32833e5850)

Wegner, N., Wait, R., Sroka, A., Eick, S., Nguyen, K.-A., Lundberg, K., Kinloch, A., Culshaw, S. , Potempa, J., and Venables, P.J. (2010) Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis. Arthritis and Rheumatism, 62 (9). pp. 2662-2672. ISSN 0004-3591 (doi:10.1002/art.27552)

2008

Culshaw, SE, Millington, OR , Brewer, JM , and McInnes, I (2008) Murine neutrophils present Class II restricted antigen. Immunology Letters, 118 (1). pp. 49-54. ISSN 0165-2478 (doi:10.1016/j.imlet.2008.02.008)

Nogueira, R. D., King, W. F., Gunda, G., Culshaw, S. , Taubman, M. A., Mattos-Graner, R. O., and Smith, D. J. (2008) Mutans Streptococcal infection induces salivary antibody to virulence proteins and associated functional domains. Infection and Immunity, 76 (8). pp. 3606-3613. ISSN 0019-9567 (doi:10.1128/IAI.00214-08)

2007

Culshaw, S., LaRosa, K., Tolani, H., Han, X., Eastcott, J. W., Smith, D. J., and Taubman, M. A. (2007) Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding. Infection and Immunity, 75 (2). pp. 915-923. ISSN 0019-9567 (doi:10.1128/IAI.01582-06)

2005

Culshaw, S, Leung, BP , Gracie, JA, Campbell, CC, Thomson, D, Gemmell, C , Liew, FY , and McInnes, IB (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35 . pp. 1438-1444. (doi:10.1002/ejui.200425661)

2004

Leung, B.P., Xu, D., Culshaw, S. , McInnes, I.B. , and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173 (1). pp. 145-150. ISSN 0022-1767

2003

Cannetti, CA, Culshaw, S , Cunha, FQ, Leung, BP , Liew, FY , and McInnes, LB (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B-4. Journal of Immunology, 171 . pp. 1009-1015.

2001

Campbell, C, Canetti, CA, Culshaw, S , Cunha, F, Gracie, JA, Hunter, D, Leung, BP , Liew, FY , and McInnes, IB (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167 . pp. 2879-2886.

This list was generated on Sat May 26 11:57:14 2012 BST.
  • What is the role of Interleukin-33 in periodontal disease
    Royal College of Surgeons of Edinburgh
    2012 - 2013
     
  • Scottish Senior Clinical Fellowship Scheme
    Scottish Funding Council
    2012 - 2016
     
  • Do age-related changes in acetylcholine production by oral keratinocytes impact on the pathogenesis of peridontal disease?
    Dunhill Medical Trust
    2011 - 2012
     
  • Do age-related changes in acetylcholine production by oral keratinocytes impact on the pathogenesis of peridontal disease?
    Dunhill Medical Trust
    2011 - 2012
     
  • Characterisation of T cell differentiation in response to the periodontal pathogen Porthyromonas gingivalis.
    The Oral and Dental Research Trust
    2011 - 2012
     
  • Does IL-17E have a regulatory role in periodontal disease via effects on oral keratinocytes?
    Tenovus-Scotland
    2011 - 2012
     
  • Development of Quantitative Assays Using Biofilm Technology.
    Technology Strategy Board
    2011 - 2012
     
  • Gums and Joints
    European Commission
    2010 - 2014
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Wellcome Trust
    2010 - 2010
     
  • The Inflammatory Response to Periodontal Pathogens
    Society of General Microbiology
    2010 - 2010
     
  • Inflammatory mediators in periodontal disease
    British Society of Periodontology
    2010 - 2010
     
  • Cytokines in periodontal disease
    Royal College of Physicians & Surgeons of Glasgow
    2009 - 2010
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Medical Research Scotland
    2009 - 2010
     
  • The relationship betweeen the host response and oral biofilm development
    Tenovus-Scotland
    2009 - 2010
     
  • Dissecting the role of the human Th17 cell in chronic inflammation
    British Society of Periodontology
    2008 - 2009