Dental School

Dr Chris Nile

  • Lecturer in Immunology (Dental School)
  • Associate Academic (Institute of Infection Immunity and Inflammation)

telephone: 01412119733
email: Christopher.Nile@glasgow.ac.uk


Biography

Christopher Nile graduated from Newcastle University with a B.Sc. in Applied Biology with honours in Biotechnology in 2000. He then went on to successfully complete a doctorate at Newcastle University in the innate immunity of the avian gastrointestinal tract (2004). He subsequently undertook a postdoctoral research position in the Academic Rheumatology group at Sheffield University investigating the epigenetic regulation of cytokine expression (2005-2007).

He then returned to Newcastle University as a postdoctoral research associate in 2007 and spent the next 3 years investigating the expression of novel cytokines and the role of physiological mediators in inducing an inflammatory response, with specific emphasis on pathogenesis of periodontal disease, Sjögren's syndrome and bladder interstitial cystitis.

In 2010 Dr Nile was appointed lecturer in Immunology at the University of Glasgow Dental School.


Research interests

Dr Nile has a long standing interest in innate immunity. Specifically, he is interested in the activation and control of inflammation and how this relates to the pathogenesis of chronic inflammatory conditions such as periodontal disease.

Jump to: 2011 | 2010 | 2009 | 2008
Number of items: 6.

2011

Grol, S., Nile, C.J. , Martinez-Martinez, P., van Koeveringe, G., de Wachter, S., de Vente, J., and Gillespie, J.I. (2011) M3 muscarinic receptor like immuno-reactivity (M3-IR) in sham-operated and obstructed guinea pig bladders. Journal of Urology, 185 (5). pp. 1959-1966. ISSN 0022-5347 (doi:10.1016/j.juro.2010.12.031)

2010

Nile, C., Barksby, E., Jitprasertwong, P., Preshaw, P.M., and Taylor, J.J. (2010) Expression and regulation of interleukin-33 in human monocytes. Immunology, 130 (2). pp. 172-180. ISSN 0019-2805 (doi:10.1111/j.1365-2567.2009.03221.x)

Nile, C.J., de Vente, J., and Gillespie, J.I. (2010) Stretch independent regulation of prostaglandin E2 production within the isolated guinea-pig lamina propria. BJU International, 105 (4). pp. 540-548. ISSN 1464-4096 (doi:10.1111/j.1464-410X.2009.08705.x)

Howard, A., Townes, C., Milona, P., Nile, C.J. , Michailidis, G., and Hall, J. (2010) Expression and functional analyses of liver expressed antimicrobial peptide-2 (LEAP-2) variant forms in human tissues. Cellular Immunology, 261 (2). pp. 128-133. ISSN 0008-8749 (doi:10.1016/j.cellimm.2009.11.010)

2009

Barksby, H.E., Nile, C.J. , Jaedicke, K.M., Taylor, J.J., and Preshaw, P.M. (2009) Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide. Clinical and Experimental Immunology, 156 (3). pp. 479-487. ISSN 0009-9104 (doi:10.1111/j.1365-2249.2009.03920.x)

2008

Nile, C.J., Read, R.C., Akil, M., Duff, G.W., and Wilson, A.G. (2008) Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis and Rheumatism, 58 (9). pp. 2686-2693. ISSN 0004-3591 (doi:10.1002/art.23758)

This list was generated on Thu May 24 14:02:09 2012 BST.
  • What is the role of Interleukin-33 in periodontal disease
    Royal College of Surgeons of Edinburgh
    2012 - 2013
     
  • Do age-related changes in acetylcholine production by oral keratinocytes impact on the pathogenesis of peridontal disease?
    Dunhill Medical Trust
    2011 - 2012
     
  • Do age-related changes in acetylcholine production by oral keratinocytes impact on the pathogenesis of peridontal disease?
    Dunhill Medical Trust
    2011 - 2012
     
  • What is the role of IL-33 in periodontal disease?
    The Oral and Dental Research Trust
    2011 - 2012
     
  • Does IL-17E have a regulatory role in periodontal disease via effects on oral keratinocytes?
    Tenovus-Scotland
    2011 - 2012