Prof Ashraf Ayoub

- Professor (Dental School)
telephone: 01412119604
email: Ashraf.Ayoub@glasgow.ac.uk
Ashraf Ayoub qualified BDS from the University of Cairo in 1982. He completed a three year Residency in Oral Surgery at Cairo University and graduated MDS. He then moved to the University of Glasgow, where he graduated PhD in 1993. He gained the FDS RCS Ed in 1992 and in 1998 completed his higher specialist training in Oral & Maxillofacial Surgery. He was appointed Senior Lecturer in Oral & Maxillofacial Surgery at the University of Glasgow in 1998 and Professor of Oral & Maxillofacial Surgery in 2003. He is currently Head of the Biotechnology & Craniofacial Sciences Section of the Dental School and Director of Dental Research.
Research Interests
Professor Ayoub’s research interests are in three main areas:
1. Three-dimensional facial modelling to assess craniofacial malformations
2. Bone Biology
This work focuses on bone bioengineering, in particular distraction osteogenesis, application of Bone Morphogenic Protein in craniofacial reconstruction, and bone healing around dental implants.
3. Management of Alcohol related facial injuries
This work examines the application of brief motivational interviews for reduction of alcohol consumption in patients with alcohol related facial injuries.
Prof Ayoub has raised over £1m in research grants to support his research and has published in excess of 74 peer-reviewed papers. He is Editor of the Oral Surgery section of the International Journal of Oral & Maxillofacial Surgery and a member of the Editorial board of the British Journal of Oral & Maxillofacial Surgery.
2012
Alfotawei, R., Busuttil Naudi, K. , Lappin, D. , Barbenel, J. , Di Silvio, L. , Ayoub, A. , and McMahon, J. (2012) The use of Tri-Calcium Phosphate (TCP) and stem cells for the regeneration of osteoperiosteal critical-size mandibular bony defects in rabbits. Journal of Cranio-Maxillofacial Surgery . ISSN 1010-5182 (In Press)
Busuttil Naudi, K., Benramadan, R., Brocklebank, L. , Ayoub, A. , Ju, X. , and Khambay, B. (2012) The virtual human face – superimposing the simultaneously captured 3D photorealistic skin surface of the face on the untextured skin image of the CBCT Scan. International Journal of Oral and Maxillofacial Surgery . ISSN 0901-5027 (In Press)
Ubaya, T., Sherriff, A. , Ayoub, A. , and Khambay, B. (2012) Soft tissue morphology of the naso-maxillary complex following surgical correction of maxillary hypoplasia. International Journal of Oral and Maxillofacial Surgery . ISSN 0901-5027 (doi:10.1016/j.ijom.2012.01.019) (In Press)
Bell, A., Lo, T-W. , Brown, D. , Bowman, A. , Siebert, J.P. , Simmons, D. , Millett, D.T., and Ayoub, A. (2012) Three-dimensional assessment of facial appearance following surgical repair of unilateral cleft lip and palate. Plastic and Reconstructive Surgery . ISSN 1529-4242 (In Press)
Busuttil Naudi, K., Ayoub, A. , McMahon, J. , Di Silvio, L., Lappin, D. , Hunter, K. , and Barbenel, J. (2012) Mandibular reconstruction in the rabbit using beta-tricalcium phosphate (β-TCP) scaffolding and recombinant bone morphogenetic protein 7 (rhBMP-7) - histological, radiographic and mechanical evaluations. Journal of Cranio-Maxillofacial Surgery . ISSN 1010-5182 (doi:10.1016/j.jcms.2012.03.005)
Busuttil Naudi, K., Lappin, D. , McMahon, J. , Ayoub, A. , and Di Silvio, L. (2012) The viability of rabbit mesenchymal stem cells on tricalcium phosphate scaffold for potential use in bone regeneration. Journal of Applied Biomaterials & Biomechanics . ISSN 1722-6899 (In Press)
Henseler, H., Smith, J. , Bowman, A. , Khambay, B. , Ju, X. , Ayoub, A. , and Ray, A. (2012) Objective evaluation of the latissimus dorsi flap for breast reconstruction using three-dimensional imaging. Journal of Plastic, Reconstructive and Aesthetic Surgery . pp. 1-7. ISSN 1748-6815 (doi:10.1016/j.bjps.2012.03.043) (In Press)
Millar, K., Bell, A. , Bowman, A. , Brown, D. , Lo, T-W. , Siebert, J.P. , Simmons, D. , and Ayoub, A. (2012) Psychological status as a function of residual scarring and facial asymmetry after surgical repair of cleft lip and palate. The Cleft Palate-Craniofacial Journal, 49 (6). ISSN 1055-6656 (doi:10.1597/10-222)
Nairn, N.J., Ayoub, A. , Barbenel, J. , Moos, K., Busuttil Naudi, K. , Ju, X. , and Khambay, B.S. (2012) Digital replacement of the distorted dentition acquired by Cone Beam Computed Tomography (CBCT): a pilot study. International Journal of Oral and Maxillofacial Surgery . ISSN 0901-5027 (In Press)
O'Neil, M., Khambay, B.S. , Moos, K.F., Barbenel, J.C. , Walker, F.S., and Ayoub, A.F. (2012) A validation of a new method for building a 3D physical model of the skull and dentition. British Journal of Oral and Maxillofacial Surgery, 50 (1). pp. 49-54. ISSN 0266-4356 (doi:10.1016/j.bjoms.2010.11.009)
O’Neil, M., Khambay, B. , Moos, K.F., Barbenel, J. , Walker, F., and Ayoub, A. (2012) Validation of a new method for building a three-dimensional physical model of the skull and dentition. British Journal of Oral and Maxillofacial Surgery, 50 (1). pp. 49-54. ISSN 0266-4356 (doi:10.1016/j.bjoms.2010.11.009)
Paul, P.E., Barbenel, J.C., Walker, F.S., Khambay, B.S. , Moos, K.F., and Ayoub, A.F. (2012) Evaluation of an improved orthognathic articulator system. 2. Accuracy of occlusal wafers. International Journal of Oral and Maxillofacial Surgery, 41 (2). pp. 155-159. ISSN 0901-5027 (doi:10.1016/j.ijom.2011.09.020)
Paul, P.E., Barbenel, J.C., Walker, F.S. , Khambay, B.S. , Moos, K.F., and Ayoub, A.F. (2012) Evaluation of an improved orthognathic articulator system: 1. Accuracy of cast orientation. International Journal of Oral and Maxillofacial Surgery, 41 (2). pp. 150-154. ISSN 0901-5027 (doi:10.1016/j.ijom.2011.09.019)
Peng, M.J.Q., Ju, X. , Khambay, B.S. , Ayoub, A.F. , Chen, C., and Bai, B. (2012) Clinical significance of creative 3D-image fusion across multimodalities [PET+CT+MR] based on characteristic coregistration. European Journal of Radiology, 81 (3). e406-e413. ISSN 0720-048X (doi:10.1016/j.ejrad.2011.12.031)
Shafi, M.I., Ayoub, A. , Ju, X. , and Khambay, B.S. (2012) The accuracy of 3D prediction planning for the surgical correction of facial deformities using Maxilim. International Journal of Oral and Maxillofacial Surgery . ISSN 0901-5027 (In Press)
2011
Ayoub, A., Garrahy, A., Millett, D., Bowman, A. , Siebert, P., Miller, J., and Ray, A. (2011) Three-Dimensional Assessment of Early Surgical Outcome in Repaired Unilateral Cleft Lip and Palate: Part 1. Nasal changes. Cleft Palate-Craniofacial Journal, 48 (5). pp. 571-577. ISSN 1055-6656 (doi:10.1597/09-147)
Ayoub, A., Garrahy, A., Millett, D., Bowman, A. , Siebert, J.P. , Miller, J., and Ray, A. (2011) Three-dimensional assessment of early surgical outcome in repaired unilateral cleft lip and palate: Part 2. Lip changes. Cleft Palate-Craniofacial Journal, 48 (5). pp. 578-583. ISSN 1055-6656 (doi:10.1597/09-148)
Ayoub, A., Bell, A. , Simmons, D. , Bowman, A. , Brown, D. , Lo, T.-W., and Xiao, Y. (2011) 3D assessment of lip scarring and residual dysmorphology following surgical repair of cleft lip and palate: a preliminary study. The Cleft Palate-Craniofacial Journal, 48 (4). pp. 379-387. ISSN 1055-6656 (doi:10.1597/10-057)
Henseler, H., Khambay, B.S. , Bowman, A., Siebert, J.P. , Oehler, S. , Ju, X. , Ayoub, A. , and Ray, A.K. (2011) Investigation into accuracy and reproducibility of a 3D breast imaging system using multiple stereo cameras. Journal of Plastic, Reconstructive and Aesthetic Surgery, 64 (5). pp. 577-582. ISSN 1748-6815 (doi:10.1016/j.bjps.2010.08.044)
2010
Barbenel, J.C., Paul, P.E., Khambay, B.S. , Walker, F.S. , Moos, K.F., and Ayoub, A.F. (2010) Errors in orthognathic surgery planning: the effect of inaccurate study model orientation. International Journal of Oral and Maxillofacial Surgery, 39 (11). pp. 1103-1108. ISSN 0901-5027 (doi:10.1016/j.ijom.2010.07.004)
Benington, P.C., Khambay, B.S. , and Ayoub, A.F. (2010) An overview of three-dimensional imaging in dentistry. Dental Update, 37 (8). pp. 494-504. ISSN 0305-5000
2009
Bakathir, A.A., Moos, K.F., Ayoub, A.F. , and Bagg, J. (2009) Factors Contributing to the Spread of Odontogenic Infections. Electronic Proceedings in Theoretical Computer Science, 9 (3). pp. 296-304. ISSN 2075-051x
Downie, J.J., Mao, Z.L., Lo, T.W.R., Barry, S. , Bock, M. , Siebert, J.P. , Bowman, A. , and Ayoub, A.F. (2009) A double-blind, clinical evaluation of facial augmentation treatments: a comparison of PRI 1, PRI 2, Zyplast ® and Perlane ®. Journal of Plastic, Reconstructive and Aesthetic Surgery, 62 (12). pp. 1636-1643. ISSN 1748-6815 (doi:10.1016/j.bjps.2008.06.056)
Ayoub, AF (2009) Response from corresponding author A Avoub to a letter to the Editor (D-09-00044) regarding article 'How accurate is model planning for orthognathic surgery?'. International Journal of Oral and Maxillofacial Surgery, 38 (9). p. 1010.
Ju, X., Siebert, J.P. , Khambay, B.S. , and Ayoub, A.F. (2009) Self-correction of 3D reconstruction from multi-view stereo images. In: IEEE 12th International Conference on Computer Vision Workshops (ICCV Workshops), 27 Sept - 4 Oct 2009, Kyoto, Japan.
2008
Sharifi, A, Jones, R, Ayoub, AF , Moos, K, Walker, FS , Khambay, BS , and McHugh, S. (2008) How accurate is model planning for orthognathic surgery? International Journal of Oral and Maxillofacial Surgery, 37 (12). pp. 1089-1093. ISSN 0901-5027 (doi:10.1016/j.ijom.2008.06.011)
Oakey, F., Ayoub, A. , Goodall, C. , Crawford, A., Smith, I., Russell, A., and Holland, I. (2008) Delivery of a brief motivational intervention to patients with alcohol-related facial injuries: Role for a specialist nurse. British Journal of Oral and Maxillofacial Surgery, 46 (6). pp. 102-106. ISSN 0266-4356 (doi:10.1016/j.bjoms.2007.11.013)
Goodall, C.A., Ayoub, A.F. , Crawford, A., Smith, I., Bowman, A. , Koppel, D., and Gilchrist, G. (2008) Nurse-delivered brief interventions for hazardous drinkers with alcohol-related facial trauma: a prospective randomised controlled trial. British Journal of Oral and Maxillofacial Surgery, 46 (2). pp. 96-101. ISSN 0266-4356 (doi:10.1016/j.bjoms.2007.11.014)
Khambay, B., Nairn, N. , Bell, A. , Miller, J., Bowman, A. , and Ayoub, A.F. (2008) Validation and reproducibility of a high-resolution camera based three-dimensional facial imaging system. British Journal of Oral and Maxillofacial Surgery, 46 (1). pp. 27-32. ISSN 0266-4356 (doi:10.1016/j.bjoms.2007.04.017)
Walker, FS, Ayoub, AF , Moos, KF, and Barbenel, J (2008) Face bow and articulator for planning orthognathic surgery: 1 face bow. British Journal of Oral and Maxillofacial Surgery, 46 (7). pp. 567-572. ISSN 0266-4356
Walker, FS, Ayoub, AF , Moos, KF, and Barbenel, J (2008) Face bow and articulator for planning orthognathic surgery: 2 articulator. British Journal of Oral and Maxillofacial Surgery, 46 (7). pp. 573-578. ISSN 0266-4356
2007
Ayoub, AF, Bell, A , McHugh, S, Moos, KF, and Nunu, YH (2007) 3D assessment of morbidity associated with lower eyelid incisions in orbital trauma. International Journal of Oral and Maxillofacial Surgery, 36 . pp. 680-686. (doi:10.1016/j.ijom.2007.05.011)
Ayoub, AF, Jones, RM, Khambay, BS , and McHugh, S (2007) The valididty of a computer-assisted simulation system for orthognathic surgery (CASSOS) for planning the surgical correction of class III skeletal deformities: single-jaw versus bimaxillary surgery. International Journal of Oral and Maxillofacial Surgery, 36 . pp. 900-908. (doi:10.1016/j.ijom.2007.05.015)
Ogbureke, KUE, Nashed, MN, and Ayoub, AF (2007) Huge peripheral osteoma of the mandible: A case report and review of the literature. Pathology Research and Practice, 203 . pp. 185-188. (doi:10.1016/j.prp.2007.01.004)
Siddiqui, A, Markose, G, Moos, KF, McMahon, J, and Ayoub, AF (2007) One miniplate versus two in the management of mandibular angle fractures: A prospective randomised study. British Journal of Oral and Maxillofacial Surgery, 45 . pp. 223-225. ISSN 0266-4356 (doi:10.1016/j.bjoms.2006.08.016)
2006
Abu-Serriah, M, Ayoub, A , Wray, D , Milne, N, Carmichael, S , and Boyd, J (2006) Contour and volume assessment of repairing mandibular osteoperiosteal continuity defects in sheep using recombinant human osteogenic protein 1. Journal of Cranio-Maxillofacial Surgery, 34 . pp. 162-167. ISSN 1010-5182 (doi:10.1016/j.jcms.2005.12.001)
Ayoub, AF, Gopalakrishnan, K, Jayade, CV, Khambay, BS , Malik, NA, Pradhan, R, Srivastava, D, and Walker, FS (2006) Skeletal stability after correction of maxillary hypoplasia by the Glasgow extra-oral distraction (GED) device. British Journal of Oral and Maxillofacial Surgery, 44 . pp. 301-307. ISSN 0266-4356 (doi:10.1016/j.bjoms.2005.07.005)
Ghandhi, D, Ayoub, AF , Pogrel, MA, MacDonald, G, Brocklebank, LM , and Moos, KF (2006) Ameloblastoma: A surgeon's dilemma. Journal of Oral and Maxillofacial Surgery, 64 . pp. 1010-1014. (doi:10.1016/j.joms.2006.03.022)
2005
Al Omari, I., Millett, D.T., and Ayoub, A.F. (2005) Methods of assessment of cleft-related facial deformity: a review. Cleft Palate-Craniofacial Journal, 42 (2). 145 -156. ISSN 1055-6656 (doi:10.1597/02-149.1)
Ayoub, AF, Richardson, W, and Barbenel, J (2005) Mandibular elongation by automatic distraction osteogenesis: The first application in humans. British Journal of Oral and Maxillofacial Surgery, 43 . pp. 324-328. ISSN 0266-4356 (doi:10.1016/j.bjoms.2005.02.008)
Fry, NK, Duncan, J, Malnick, H, Warner, M, Smith, AJ , Jackson, MS, and Ayoub, AF (2005) Bordetella petrii clinical isolate. Emerging Infectious Diseases, 11 . pp. 1131-1133.
Garrahy, A, Millett, D, and Ayoub, AF (2005) Early assessment of dental arch development in repaired unilateral cleft lip and unilateral cleft lip and palate versus controls. Cleft Palate-Craniofacial Journal, 42 (4). pp. 385-391. ISSN 1055-6656 (doi:10.1597/03-159.1)
Hajeer, M.Y., Mao, Z., Millett, D.T., Ayoub, A.F. , and Siebert, J.P. (2005) A new three-dimensional method of assessing facial volumetric changes after orthognathic treatment. Cleft Palate-Craniofacial Journal, 42 (2). 113 -120. ISSN 1055-6656 (doi:10.1597/03-132.1)
Jayade, C, Ayoub, AF , Khambay, BS, Walker, FS, Gopalakrishnan, K, Malik, NA, Srivastava, DS, and Pradhan, R (2005) Skeletal stability following correction of maxillary hypoplasia using the Glasgow Extra-oral Distraction osteogenesis device. British Journal of Oral and Maxillofacial Surgery . ISSN 0266-4356
2004
Abu-Serriah, M.M., Ayoub, A.F. , Odell, E., Carmichael, S. , and Wray, D. (2004) A minimally invasive novel design for a vascular-pedicled bone segment for experimental studies of reconstruction of mandibular defects. British Journal of Oral and Maxillofacial Surgery, 42 (3). 236 -240. ISSN 0266-4356 (doi:10.1016/j.bjoms.2004.01.002)
Hajeer, M.Y., Millett, D.T., Ayoub, A.F. , and Siebert, J.P. (2004) Current products and practices: applications of 3D imaging in orthodontics: Part I. Journal of Orthodontics, 31 (1). pp. 62-70. ISSN 1465-3133 (doi:10.1179/146531204225011346)
Hajeer, M.Y., Millett, D.T., Ayoub, A.F. , and Siebert, J.P. (2004) Current products and practices: applications of 3D imaging in orthodontics: Part II. Journal of Orthodontics, 31 (2). pp. 154-162. ISSN 1465-3125 (doi:10.1179/146531204225020472)
Hood, C.A., Hosey, M.T. , Bock, M. , White, J., Ray, A. , and Ayoub, A.F. (2004) Facial characterization of infants with cleft lip and palate using a three-dimensional capture technique. Cleft Palate-Craniofacial Journal, 41 (1). 27 -35. ISSN 1055-6656 (doi:10.1597/02-143)
Hood, CA, Hosey, MT, Bock, M, White, J, Ray, A, and Ayoub, AF (2004) Facial characterization of infants with cleft lip and palate using a 3D capture technique. Craniofacial and Cleft Palate Journal, 41 . pp. 27-35.
2003
Abu-Serriah, M, Ayoub, A , Boyd, J, Paterson, C, and Wray, D (2003) The role of ultrasound in monitoring reconstruction of mandibular continuity defects using osteogenic protein-1 (rhOP-1). International Journal of Oral and Maxillofacial Surgery, 32 . pp. 619-627.
Al Omari, I., Millett, D.T., Ayoub, A.F. , Bock, M. , Ray, A., Dunaway, D., and Crampin, L. (2003) An appraisal of three methods of rating facial deformity in patients with repaired complete unilateral cleft lip and palate. Cleft Palate-Craniofacial Journal, 40 (5). 530 -537. ISSN 1055-6656 (doi:10.1597/1545-1569(2003)040<0530:AAOTMO>2.0.CO;2)
Ayoub, A.F., Garrahy, A., Hood, C., White, J., Bock, M., Siebert, J.P. , Spencer, R., and Ray, A. (2003) Validation of a vision-based, three-dimensional facial imaging system. Cleft Palate-Craniofacial Journal, 40 (5). 523 -529. ISSN 1545-1569 (doi:10.1597/02-067)
Koppel, DA, Foy, RH, McCaul, JA, Logan, J, Hadley, DM, and Ayoub, AF (2003) The reliability of 'Analyze' software in measuring orbital volume utilizing CT-derived data. Journal of Cranio-Maxillofacial Surgery, 31 (2). pp. 88-91. ISSN 1010-5182
2002
Ayoub, AF, Duncan, CM, Mclean, GR, Moos, KF, and Chibbaro, PD (2002) Patient and family response to lengthening of the facial bones by distraction osteogenesis. British Journal of Oral and Maxillofacial Surgery, 40 . pp. 381-464. ISSN 0266-4356
Hajeer, M.Y., Ayoub, A.F. , Millett, D.T., Bock, M., and Siebert, J.P. (2002) Three-dimensional imaging in orthognathic surgery: the clinical application of a new method. International Journal of Adult Orthodontics and Orthognathic Surgery, 17 (4). 318 -330. ISSN 0742-1931
2001
Ayoub, A.F., Richardson, W., Koppel, D., Thompson, H. , Lucas, M., Schwarz, T., Smith, L., and Boyd, J. (2001) Segmental mandibular reconstruction by microincremental automatic distraction osteogenesis: an animal study. British Journal of Oral and Maxillofacial Surgery, 39 (5). 356 -364. ISSN 1532-1940 (doi:10.1054/bjom.2001.0658)
1998
Ayoub, A.F., Siebert, J.P. , Moos, K., Wray, D. , Urquhart, C., and Niblett, T. (1998) A vision-based three-dimensional capture system for maxillofacial assessment and surgical planning. British Journal of Oral and Maxillofacial Surgery, 36 (5). pp. 353-357. ISSN 0266-4356 (doi:10.1016/S0266-4356(98)90646-5)
Forthcoming Publications
Henseler, H., Smith, J., Bowman, A. , Khambay, B. , Ju, X. , Ayoub, A. , and Ray, A. Investigation into variation and errors of a three-dimensional breast imaging system using multiple stereo cameras. Plastic and Reconstructive Surgery . ISSN 0032-1052 (In Press)
- The analysis of three-dimensional facial dysmorphology
Wellcome Trust
2009 - 2012
- New Curriculum for Management of Maxillofacial Deformities
European Commission
2008 - 2009
- Reduction of alcohol abuse, aggression and facial injury - a randomised trial of brief intervention strategies in patients with alcohol related facial injuries
Strathclyde Police
2007 - 2009
- A multidisciplinary assessment of residual deformities following surgical repair of cleft lip and palate
Scottish Executive Health Department
2005 - 2009
- New Curriculum for Management of Maxillofacial Deformities
European Commission
2005 - 2009
- Predictors of outcome following brief intervention in patients with alcohol related facial injuries
Alcohol Education and Research Council
2003 - 2005
