Dr Affar Karimullah
- Lecturer (School of Chemistry)
telephone:
+44 141 330 4466
email:
Affar.Karimullah@glasgow.ac.uk
A3-23, Joseph Black Building, University Place, University of Glasgow, Glasgow, UK., G12 8QQ
https://orcid.org/0000-0002-8792-9829Research interests
Research Interests: My interest is to innovate new sensors for life science applications. Previously I have worked on using conducting polymers for in-situ detection of cell growth and stem cell differentiation to aid large scale cell culture activities. My current interests lie in the use of optical techniques to perform diagnostics and improve our capabilities for precision medicine. As part of my EPSRC UKRI Innovation Fellowship, I aim to use chiral nano-patterned gold surfaces to create biostructure sensitive assays that are able to detect serious medical conditions such as Sepsis and Invasive Aspergillosis in shorter periods of time and outside a laboratory setting. These Chiral Plasmonic Assayswill use technology pioneered in Glasgow, specifically, low cost Disposable Plasmonicsand Chiral Plasmonic Sensingthat will enable a commercially realisable technological breakthrough.
My multidisciplinary group encompasses the fields of nanotechnology, optical instrument design, biochemistry and biomedical engineering. We create novel microscopy systems and metamaterials to push the boundaries of biosensing. Research commercialisation and impact is fundamental to our activity. Hence, industrial collaborations with HORIBA Scientific and Avacta Lifesciences are an important aspect to fulfilling the research and impact activities.
Research groups
Publications
2024
Xia, Y., Yalagala, B. P., Karimullah, A. S. , Heidari, H. and Ghannam, R. (2024) Beyond flexibility: transparent silver nanowire electrodes on patterned surfaces for reconfigurable devices. Advanced Engineering Materials, 26(1), 2301165. (doi: 10.1002/adem.202301165)
2023
Xia, Y., Li, H., Vaskeviciute, M. , Faccio, D. , Karimullah, A. , Heidari, H. and Ghannam, R. (2023) Cholesteric Liquid Crystal Based Reconfigurable Optical Combiner for Head-Mounted Display Application. IEEE VR 2024, Orlando, FL, USA, 16-21 Mar 2024. (Accepted for Publication)
Sperling, J. R. et al. (2023) A cross-reactive plasmonic sensing array for drinking water assessment. Environmental Science: Nano, 10(12), pp. 3500-3508. (doi: 10.1039/D3EN00565H) (PMID:38073859)
Wallace, S. et al. (2023) Multiplexed biosensing of proteins and virions with disposable plasmonic assays. ACS Sensors, 8(9), pp. 3338-3348. (doi: 10.1021/acssensors.2c02238) (PMID:37610841) (PMCID:PMC10521139)
Olshtrem, A. et al. (2023) Chiral plasmonic response of 2D Ti3C2Tx flakes: realization and applications. Advanced Functional Materials, 33(30), 2212786. (doi: 10.1002/adfm.202212786)
Kartau, M. et al. (2023) Chiral metafilms and surface enhanced Raman scattering for enantiomeric discrimination of helicoid nanoparticles. Advanced Optical Materials, 11(9), 2202991. (doi: 10.1002/adom.202202991)
Guselnikova, O., Elashnikov, R., Svorcik, V., Kartau, M., Gilroy, C., Gadegaard, N. , Kadodwala, M. , Karimullah, A. S. and Lyutakov, O. (2023) Coupling of plasmonic hot spots with shurikens for superchiral SERS-based enantiomer recognition. Nanoscale Horizons, 8(4), pp. 499-508. (doi: 10.1039/D3NH00008G) (PMID:36752733)
2022
Tabouillot, V. et al. (2022) Near-field probing of optical superchirality with plasmonic circularly polarized luminescence for enhanced bio-detection. ACS Photonics, 9(11), pp. 3617-3624. (doi: 10.1021/acsphotonics.2c01073) (PMID:36411820)
Gilroy, C., Koyroytsaltis-McQuire, D. J. P., Gadegaard, N. , Karimullah, A. S. and Kadodwala, M. (2022) Superchiral hot-spots in “real” chiral plasmonic structures. Materials Advances, 3(1), pp. 346-354. (doi: 10.1039/D1MA00831E)
Koyroytsaltis-McQuire, D. J.P., Gilroy, C., Barron, L. D., Gadegaard, N. , Karimullah, A. S. and Kadodwala, M. (2022) Detecting antibody–antigen interactions with chiral plasmons: factors influencing chiral plasmonic sensing. Advanced Photonics Research, 3(1), 2100155. (doi: 10.1002/adpr.202100155)
2021
Hajji, M. et al. (2021) A chiral quantum metamaterial for hypersensitive biomolecule detection. ACS Nano, 15(12), pp. 19905-19916. (doi: 10.1021/acsnano.1c07408) (PMID:34846858)
Gilroy, C., McKay, K., Devine, M., Webster, R. W.H., Gadegaard, N. , Karimullah, A. , Maclaren, D. and Kadodwala, M. (2021) Active chiral plasmonics: flexoelectric control of nanoscale chirality. Advanced Photonics Research, 2(1), 2000062. (doi: 10.1002/adpr.202000062)
2020
Kakkar, T. et al. (2020) Superchiral near fields detect virus structure. Light: Science and Applications, 9(1), 195. (doi: 10.1038/s41377-020-00433-1) (PMID:33298854) (PMCID:PMC7705013)
Kelly, C. et al. (2020) Controlling the symmetry of inorganic ionic nanofilms with optical chirality. Nature Communications, 11, 5169. (doi: 10.1038/s41467-020-18869-9) (PMID:33057000) (PMCID:PMC7560753)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. S. , Barron, L., Gadegaard, N. , Lapthorn, A. J. and Kadodwala, M. (2020) Biomacromolecular charge chirality detected using chiral plasmonic nanostructures. Nanoscale Horizons, 5, pp. 336-344. (doi: 10.1039/C9NH00525K)
2019
Gilroy, C., Hashiyada, S., Endo, K., Karimullah, A. S. , Barron, L., Okamoto, H., Togawa, Y. and Kadodwala, M. (2019) Roles of superchirality and interference in chiral plasmonic biodetection. Journal of Physical Chemistry C, 123(24), pp. 15195-15203. (doi: 10.1021/acs.jpcc.9b02791)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. , Barron, L., Gadegaard, N. , Lapthorn, A. and Kadodwala, M. (2019) Probing specificity of protein-protein interactions with chiral plasmonic nanostructures. Journal of Physical Chemistry Letters, 10, pp. 6105-6111. (doi: 10.1021/acs.jpclett.9b02288) (PMID:31549842)
2018
Kelly, C., Tullius, R., Lapthorn, A. J. , Gadegaard, N. , Cooke, G. , Barron, L. D., Karimullah, A. S. , Rotello, V. M. and Kadodwala, M. (2018) Chiral plasmonic fields probe structural order of biointerfaces. Journal of the American Chemical Society, 140(27), pp. 8509-8517. (doi: 10.1021/jacs.8b03634) (PMID:29909628)
Paterson, G. W. , Karimullah, A. S. , Smith, S. G., Kadodwala, M. and MacLaren, D. A. (2018) Symmetry reduction and shape effects in concave chiral plasmonic structures. Journal of Physical Chemistry C, 122(9), pp. 5049-5056. (doi: 10.1021/acs.jpcc.7b12260)
Kelly, C., Khorashad, L. K., Gadegaard, N. , Barron, L. D., Govorov, A. O., Karimullah, A. S. and Kadodwala, M. (2018) Controlling metamaterial transparency with superchiral fields. ACS Photonics, 5(2), pp. 535-543. (doi: 10.1021/acsphotonics.7b01071)
2017
Tullius, R. et al. (2017) Superchiral plasmonic phase sensitivity for fingerprinting of protein interface structure. ACS Nano, 11(12), pp. 12049-12056. (doi: 10.1021/acsnano.7b04698) (PMID:29220155)
2016
Jack, C., Karimullah, A. S. , Leyman, R., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2016) Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures. Nano Letters, 16(9), pp. 5806-5814. (doi: 10.1021/acs.nanolett.6b02549) (PMID:27547978)
Jack, C. et al. (2016) Spatial control of chemical processes on nanostructures through nano-localized water heating. Nature Communications, 7, 10946. (doi: 10.1038/ncomms10946) (PMID:26961708) (PMCID:PMC4792951)
2015
Karimullah, A. S. , Jack, C., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2015) Disposable plasmonics: plastic templated plasmonic metamaterials with tunable chirality. Advanced Materials, 27(37), pp. 5610-5616. (doi: 10.1002/adma.201501816)
Paterson, G. W. , Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. A. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. Journal of Physics: Conference Series, 644(1), 012005. (doi: 10.1088/1742-6596/644/1/012005)
Tullius, R., Karimullah, A. S. , Rodier, M., Fitzpatrick, B., Gadegaard, N. , Barron, L. D., Rotello, V. M., Cooke, G. , Lapthorn, A. and Kadodwala, M. (2015) "Superchiral” spectroscopy: detection of protein higher order hierarchical structure with chiral plasmonic nanostructures. Journal of the American Chemical Society, 137(26), pp. 8380-8383. (doi: 10.1021/jacs.5b04806) (PMID:26102606)
2013
Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi: 10.1039/c3nr04746f)
Karimullah, A. S. , Cumming, D. R.S. , Riehle, M. and Gadegaard, N. (2013) Development of a conducting polymer cell impedance sensor. Sensors and Actuators B: Chemical, 176, pp. 667-674. (doi: 10.1016/j.snb.2012.09.075)
Articles
Xia, Y., Yalagala, B. P., Karimullah, A. S. , Heidari, H. and Ghannam, R. (2024) Beyond flexibility: transparent silver nanowire electrodes on patterned surfaces for reconfigurable devices. Advanced Engineering Materials, 26(1), 2301165. (doi: 10.1002/adem.202301165)
Sperling, J. R. et al. (2023) A cross-reactive plasmonic sensing array for drinking water assessment. Environmental Science: Nano, 10(12), pp. 3500-3508. (doi: 10.1039/D3EN00565H) (PMID:38073859)
Wallace, S. et al. (2023) Multiplexed biosensing of proteins and virions with disposable plasmonic assays. ACS Sensors, 8(9), pp. 3338-3348. (doi: 10.1021/acssensors.2c02238) (PMID:37610841) (PMCID:PMC10521139)
Olshtrem, A. et al. (2023) Chiral plasmonic response of 2D Ti3C2Tx flakes: realization and applications. Advanced Functional Materials, 33(30), 2212786. (doi: 10.1002/adfm.202212786)
Kartau, M. et al. (2023) Chiral metafilms and surface enhanced Raman scattering for enantiomeric discrimination of helicoid nanoparticles. Advanced Optical Materials, 11(9), 2202991. (doi: 10.1002/adom.202202991)
Guselnikova, O., Elashnikov, R., Svorcik, V., Kartau, M., Gilroy, C., Gadegaard, N. , Kadodwala, M. , Karimullah, A. S. and Lyutakov, O. (2023) Coupling of plasmonic hot spots with shurikens for superchiral SERS-based enantiomer recognition. Nanoscale Horizons, 8(4), pp. 499-508. (doi: 10.1039/D3NH00008G) (PMID:36752733)
Tabouillot, V. et al. (2022) Near-field probing of optical superchirality with plasmonic circularly polarized luminescence for enhanced bio-detection. ACS Photonics, 9(11), pp. 3617-3624. (doi: 10.1021/acsphotonics.2c01073) (PMID:36411820)
Gilroy, C., Koyroytsaltis-McQuire, D. J. P., Gadegaard, N. , Karimullah, A. S. and Kadodwala, M. (2022) Superchiral hot-spots in “real” chiral plasmonic structures. Materials Advances, 3(1), pp. 346-354. (doi: 10.1039/D1MA00831E)
Koyroytsaltis-McQuire, D. J.P., Gilroy, C., Barron, L. D., Gadegaard, N. , Karimullah, A. S. and Kadodwala, M. (2022) Detecting antibody–antigen interactions with chiral plasmons: factors influencing chiral plasmonic sensing. Advanced Photonics Research, 3(1), 2100155. (doi: 10.1002/adpr.202100155)
Hajji, M. et al. (2021) A chiral quantum metamaterial for hypersensitive biomolecule detection. ACS Nano, 15(12), pp. 19905-19916. (doi: 10.1021/acsnano.1c07408) (PMID:34846858)
Gilroy, C., McKay, K., Devine, M., Webster, R. W.H., Gadegaard, N. , Karimullah, A. , Maclaren, D. and Kadodwala, M. (2021) Active chiral plasmonics: flexoelectric control of nanoscale chirality. Advanced Photonics Research, 2(1), 2000062. (doi: 10.1002/adpr.202000062)
Kakkar, T. et al. (2020) Superchiral near fields detect virus structure. Light: Science and Applications, 9(1), 195. (doi: 10.1038/s41377-020-00433-1) (PMID:33298854) (PMCID:PMC7705013)
Kelly, C. et al. (2020) Controlling the symmetry of inorganic ionic nanofilms with optical chirality. Nature Communications, 11, 5169. (doi: 10.1038/s41467-020-18869-9) (PMID:33057000) (PMCID:PMC7560753)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. S. , Barron, L., Gadegaard, N. , Lapthorn, A. J. and Kadodwala, M. (2020) Biomacromolecular charge chirality detected using chiral plasmonic nanostructures. Nanoscale Horizons, 5, pp. 336-344. (doi: 10.1039/C9NH00525K)
Gilroy, C., Hashiyada, S., Endo, K., Karimullah, A. S. , Barron, L., Okamoto, H., Togawa, Y. and Kadodwala, M. (2019) Roles of superchirality and interference in chiral plasmonic biodetection. Journal of Physical Chemistry C, 123(24), pp. 15195-15203. (doi: 10.1021/acs.jpcc.9b02791)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. , Barron, L., Gadegaard, N. , Lapthorn, A. and Kadodwala, M. (2019) Probing specificity of protein-protein interactions with chiral plasmonic nanostructures. Journal of Physical Chemistry Letters, 10, pp. 6105-6111. (doi: 10.1021/acs.jpclett.9b02288) (PMID:31549842)
Kelly, C., Tullius, R., Lapthorn, A. J. , Gadegaard, N. , Cooke, G. , Barron, L. D., Karimullah, A. S. , Rotello, V. M. and Kadodwala, M. (2018) Chiral plasmonic fields probe structural order of biointerfaces. Journal of the American Chemical Society, 140(27), pp. 8509-8517. (doi: 10.1021/jacs.8b03634) (PMID:29909628)
Paterson, G. W. , Karimullah, A. S. , Smith, S. G., Kadodwala, M. and MacLaren, D. A. (2018) Symmetry reduction and shape effects in concave chiral plasmonic structures. Journal of Physical Chemistry C, 122(9), pp. 5049-5056. (doi: 10.1021/acs.jpcc.7b12260)
Kelly, C., Khorashad, L. K., Gadegaard, N. , Barron, L. D., Govorov, A. O., Karimullah, A. S. and Kadodwala, M. (2018) Controlling metamaterial transparency with superchiral fields. ACS Photonics, 5(2), pp. 535-543. (doi: 10.1021/acsphotonics.7b01071)
Tullius, R. et al. (2017) Superchiral plasmonic phase sensitivity for fingerprinting of protein interface structure. ACS Nano, 11(12), pp. 12049-12056. (doi: 10.1021/acsnano.7b04698) (PMID:29220155)
Jack, C., Karimullah, A. S. , Leyman, R., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2016) Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures. Nano Letters, 16(9), pp. 5806-5814. (doi: 10.1021/acs.nanolett.6b02549) (PMID:27547978)
Jack, C. et al. (2016) Spatial control of chemical processes on nanostructures through nano-localized water heating. Nature Communications, 7, 10946. (doi: 10.1038/ncomms10946) (PMID:26961708) (PMCID:PMC4792951)
Karimullah, A. S. , Jack, C., Tullius, R., Rotello, V. M., Cooke, G. , Gadegaard, N. , Barron, L. D. and Kadodwala, M. (2015) Disposable plasmonics: plastic templated plasmonic metamaterials with tunable chirality. Advanced Materials, 27(37), pp. 5610-5616. (doi: 10.1002/adma.201501816)
Paterson, G. W. , Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. A. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. Journal of Physics: Conference Series, 644(1), 012005. (doi: 10.1088/1742-6596/644/1/012005)
Tullius, R., Karimullah, A. S. , Rodier, M., Fitzpatrick, B., Gadegaard, N. , Barron, L. D., Rotello, V. M., Cooke, G. , Lapthorn, A. and Kadodwala, M. (2015) "Superchiral” spectroscopy: detection of protein higher order hierarchical structure with chiral plasmonic nanostructures. Journal of the American Chemical Society, 137(26), pp. 8380-8383. (doi: 10.1021/jacs.5b04806) (PMID:26102606)
Kadodwala, M. , Abdulrahman, N., Syme, C. D. , Jack, C., Barron, L. D., Karimullah, A. and Gadegaard, N. (2013) The origin of off–resonance non-linear optical activity of a gold chiral nanomaterial. Nanoscale, 5(24), pp. 12651-12657. (doi: 10.1039/c3nr04746f)
Karimullah, A. S. , Cumming, D. R.S. , Riehle, M. and Gadegaard, N. (2013) Development of a conducting polymer cell impedance sensor. Sensors and Actuators B: Chemical, 176, pp. 667-674. (doi: 10.1016/j.snb.2012.09.075)
Conference or Workshop Item
Xia, Y., Li, H., Vaskeviciute, M. , Faccio, D. , Karimullah, A. , Heidari, H. and Ghannam, R. (2023) Cholesteric Liquid Crystal Based Reconfigurable Optical Combiner for Head-Mounted Display Application. IEEE VR 2024, Orlando, FL, USA, 16-21 Mar 2024. (Accepted for Publication)
Research datasets
2023
Sperling, J. R. , Poursat, B., Savage, L., Christie, I., Cuthill, C., McGuire, K. , Karimullah, A. S. , Robbie, J. , Gauchotte-Lindsay, C. , Peveler, W. J. and Clark, A. W. (2023) A nanoplasmonic sensor array for optical inline drinking water assessment: a pilot study with rural Scottish water treatment works. [Data Collection]
2018
Paterson, G., Karimullah, A. , Smith, S., Kadodwala, M. and MacLaren, D. (2018) Symmetry Reduction and Shape Effects in Concave Chiral Plasmonic Structures. [Data Collection]
2015
Paterson, G., Karimullah, A. , Williamson, S. D. R., Kadodwala, M. and MacLaren, D. (2015) Electron energy loss spectroscopy of a chiral plasmonic structure. [Data Collection]
