Professor Keith Muir

  • SINAPSE Chair of Clinical Imaging (Stroke and Brain Imaging)

telephone: 0141 451 5874

Ground Floor, Office Block
Queen Elizabeth University Hospital
Glasgow G51 4TF

Major interests are in the treatment of acute stroke and the application of advanced brain imaging techniques to aid treatment decisions in acute stroke; thrombolysis for stroke; clinical trials and clinical trial design in acute stroke; and the inherited syndrome CADASIL (Cerebral Autosomal Dominant Arteripathy with Subcortical Infarction and Leucoencephalopathy).

Research work is predominantly undertaken in the South Glasgow Acute Stroke Service, based in the Institute of Neurological Sciences, where we have established a unit with the highest rates of IV thrombolytic treatment in the UK (and in the top 10 in Europe). Currently, we use a mixture of advanced imaging techniques including CT perfusion and CT angiography, MRI (including novel sequences being developed locally for metabolic imaging) and TCD. The specific techniques depend upon the individual research question – recent work has included the use of MR spectroscopy and DWI lesion volume evolution to investigate the therapeutic effects of insulin treatment for hyperglycaemia in acute stroke, and ongoing studies are investigating the influence of hyperglycaemia on recanalisation and reperfusion rates in acute stroke.

The stroke imaging group includes clinical neuroradiologists, physicists, and neuroscientists, and there is close collaboration between preclinical imaging in rodent models of cerebral ischaemia with the clinical studies.

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Number of items: 108.


Muir, K. (2016) Interaction of recanalization, intracerebral hemorrhage and cerebral edema after intravenous thrombolysis. Stroke, (Accepted for Publication)

Moreton, F. C., Dani, K. A., Goutcher, C., O'Hare, K., and Muir, K. W. (2016) Respiratory challenge MRI: practical aspects. NeuroImage: Clinical, (doi:10.1016/j.nicl.2016.05.003) (Accepted for Publication)

Cheripelli, B. K., Huang, X., McVerry, F., and Muir, K. (2016) What is the relationship among penumbra volume, collaterals, and time since onset in the first 6 h after acute ischemic stroke? International Journal of Stroke, 11(3), pp. 338-346. (doi:10.1177/1747493015620807) (PMID:26763919)

Merenda, A., Muir, K. W., and Koch, S. (2016) Cracking the role of cocaine in stroke. Stroke, 47(4), pp. 909-910. (doi:10.1161/strokeaha.116.012681) (PMID:26965852)

Muir, K. W., and White, P. (2016) HERMES: messenger for stroke interventional treatment. Lancet, 387(10029), pp. 1695-1697. (doi:10.1016/s0140-6736(16)00351-2) (PMID:26898854)

Østergaard, L., Engedal, T. S., Moreton, F., Hansen, M. B., Wardlaw, J. M., Dalkara, T., Markus, H. S., and Muir, K. W. (2016) Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. Journal of Cerebral Blood Flow and Metabolism, 36(2), pp. 302-325. (doi:10.1177/0271678X15606723) (PMID:26661176) (PMCID:PMC4759673)

Cullen, B., Moreton, F. C., Stringer, M. S., Krishnadas, R., Kalladka, D., López-González, M. R., Santosh, C., Schwarzbauer, C., and Muir, K. W. (2016) Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Journal of Cerebral Blood Flow and Metabolism, (doi:10.1177/0271678X16636395) (PMID:26929239) (Early Online Publication)

Kalladka, D. et al. (2016) Pilot Investigation of Human Neural Stem Cells in Chronic Ischaemic Stroke Patients (PISCES): A Phase 1, First-in-Man Study. Lancet, (Accepted for Publication)

Lopez Gonzalez, M.R., Foo, S.Y., Holmes, W.M., Stewart, W., Condon, B., Muir, K.W., Welch, G., and Forbes, K.P. (2016) Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study. Journal of Neuroimaging, (doi:10.1111/jon.12332) (PMID:26919134) (In Press)

Muir, K. (2016) No space Left for Intravenous thrombolysis in acute stroke. Internal and Emergency Medicine, (doi:10.1007/s11739-016-1448-0) (Early Online Publication)


Moreton, F., Santosh, C., McArthur, K., and Muir, K. (2015) Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy. Neurology, 85(24), pp. 2177-2179. (doi:10.1212/WNL.0000000000002214) (PMID:26567267)

Huang, X., Moreton, F., Kalladka, D., Cheripelli, B. K., Macisaac, R., Tait, R. C., and Muir, K. (2015) Coagulation and fibrinolytic activity of tenecteplase and alteplase in acute ischemic stroke. Stroke, 46(12), pp. 3543-3546. (doi:10.1161/strokeaha.115.011290) (PMID:26514192)

Macisaac, R. L. et al. (2015) A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: ThRombEctomy and tPA (TREAT) analysis: statistical analysis plan for a sequential meta-anal. International Journal of Stroke, 10(Sup), pp. 136-144. (doi:10.1111/ijs.12622) (PMID:26352438)

Huang, X., Cheripelli, B. K., Lloyd, S. M., Kalladka, D., Moreton, F. C., Siddiqui, A., Ford, I., and Muir, K. W. (2015) Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST): phase 2 randomised clinical trial. Lancet Neurology, 14(4), pp. 368-376. (doi:10.1016/S1474-4422(15)70017-7) (PMID:25726502)

Ramani, L., Huang, X., Cheripelli, B., and Muir, K. W. (2015) Intravenous thrombolysis for acute stroke: current standards and future directions. Current Treatment Options in Cardiovascular Medicine, 17(3), 16. (doi:10.1007/s11936-015-0373-2) (PMID:25778425)

Wollenweber, F.A. et al. (2015) Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro. Stroke, 46(3), pp. 786-792. (doi:10.1161/STROKEAHA.114.007472) (PMID:25604251)

Khatri, P. et al. (2015) State of acute endovascular therapy: report from the 12th thrombolysis, Thrombectomy, and acute stroke therapy conference. Stroke, 46(6), pp. 1727-1734. (doi:10.1161/STROKEAHA.115.008782) (PMID:25944325)


McVerry, F., Dani, K. A., MacDougall, N. J.J., Macleod, M. J., Wardlaw, J., and Muir, K. W. (2014) Derivation and evaluation of thresholds for core and tissue at risk of infarction using CT perfusion. Journal of Neuroimaging, 24(6), pp. 562-568. (doi:10.1111/jon.12134)

Urfer, R., Moebius, H. J., Skoloudik, D., Santamarina, E., Sato, W., Mita, S., and Muir, K. W. (2014) Phase II trial of the sigma-1 receptor agonist cutamesine (SA4503) for recovery enhancement after acute ischemic stroke. Stroke, 45(11), pp. 3304-3310. (doi:10.1161/STROKEAHA.114.005835) (PMID:25270629)

Thomalla, G. et al. (2014) A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP). International Journal of Stroke, 9(6), pp. 829-836. (doi:10.1111/ijs.12011)

Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Dennis, M., Sandercock, P. A. G., Muir, K., and Wardlaw, J. M. (2014) Diffusion-weighted imaging and diagnosis of transient ischemic attack. Annals of Neurology, 75(1), pp. 67-76. (doi:10.1002/ana.24026) (PMID:24085376) (PMCID:PMC4223937)

Moreton, F., Razvi, S., Davidson, R., and Muir, K. (2014) Changing clinical patterns and increasing prevalence in CADASIL. Acta Neurologica Scandinavica, 130(3), pp. 197-203. (doi:10.1111/ane.12266)

Robertson, C. A., McCabe, C., Lopez-Gonzalez, M. R., Deuchar, G. A., Dani, K., Holmes, W. M., Muir, K. W., Santosh, C., and Macrae, I. M. (2014) Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. International Journal of Stroke, 10(1), pp. 42-50. (doi:10.1111/ijs.12327)

Rodie, M. E., Forbes, K. P., and Muir, K. (2014) Advances in neuroimaging. In: Hiort, O. and Ahmed, S.F. (eds.) Understanding Differences and Disorders of Sex Development (DSD). Series: Endocrine development (27). Karger: Basel, pp. 63-75. ISBN 9783318025583 (doi:10.1159/000363628)

Savitz, S. I. et al. (2014) Stem cells as an emerging paradigm in Stroke 3: enhancing the development of clinical trials. Stroke, 45(2), pp. 634-639. (doi:10.1161/STROKEAHA.113.003379)


Hill, M., and Muir, K.W. (2013) INTERACT-2: should blood pressure be aggressively lowered acutely after intracerebral hemorrhage? Stroke, 44(10), pp. 2951-2952. (doi:10.1161/STROKEAHA.113.002790)

Muir, K.W. (2013) STICH 2: does decompression have a role in superficial intracerebral hematoma? International Journal of Stroke, 8(7), pp. 540-541. (doi:10.1111/ijs.12182)

Brazzelli, M., Shuler, K., Quayyum, Z., Hadley, D., Muir, K., McNamee, P., De Wilde, J., Dennis, M., Sandercock, P., and Wardlaw, J. M. (2013) Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK. BMJ Open, 3(8), e003359. (doi:10.1136/bmjopen-2013-003359)

Scalzo, F. et al. (2013) Multi-center prediction of hemorrhagic transformation in acute ischemic stroke using permeability imaging features. Magnetic Resonance Imaging, 31(6), pp. 961-969. (doi:10.1016/j.mri.2013.03.013)

Rossit, R., Olsen, L., Butler, S., Muir, K., and Harvey, M. (2013) The neural basis of reflexive and volitional saccades: evidence from lesion-symptom mapping with stroke patients. Behavioural Neurology, 27(3), pp. 388-389. (doi:10.3233/BEN-139900)

Tarr, D., Graham, D., Roy, L.A., Holmes, W.M., McCabe, C., Macrae, I.M., Muir, K.W., and Dewar, D. (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. Journal of Cerebral Blood Flow and Metabolism, 33(10), pp. 1556-1563. (doi:10.1038/jcbfm.2013.107)

Wintermark, M. et al. (2013) Acute stroke imaging research roadmap II. Stroke, 44(9), pp. 2628-2639. (doi:10.1161/STROKEAHA.113.002015)

van der Hoeven, E.J.R.J. et al. (2013) The Basilar artery international cooperation study (BASICS): study protocol for a randomised controlled trial. Trials, 14(200), (doi:10.1186/1745-6215-14-200)


Dani, K.A., Santosh, C., Brennan, D., Hadley, D.M., and Muir, K.W. (2012) Crossed cerebellar diaschisis: insights into oxygen challenge MRI. Journal of Cerebral Blood Flow and Metabolism, 32(12), pp. 2114-2117. (doi:10.1038/jcbfm.2012.142)

Muir, K.W. (2012) Imaging and treatment response after ischaemic stroke. Lancet Neurology, 11(10), pp. 838-839. (doi:10.1016/S1474-4422(12)70207-7)

Sinden, J.D., and Muir, K.W. (2012) Stem cells in stroke treatment: the promise and the challenges. International Journal of Stroke, 7(5), pp. 426-434. (doi:10.1111/j.1747-4949.2012.00840.x)

Rossit, S., McIntosh, R.D., Malhotra, P., Butler, S.H., Muir, K., and Harvey, M. (2012) Attention in action: evidence from on-line corrections in left visual neglect. Neuropsychologia, 50(6), pp. 1124-1135. (doi:10.1016/j.neuropsychologia.2011.10.004)

Cooper, S.A., Joshi, A.C., Seenan, P.J., Hadley, D.M., Muir, K.W., Leigh, R.J., and Metcalfe, R.A. (2012) Akinetopsia: acute presentation and evidence for persisting defects in motion vision. Journal of Neurology, Neurosurgery and Psychiatry, 83(2), pp. 229-230. (doi:10.1136/jnnp.2010.223727)

Dani, K.A., Thomas, R.G.R., Chappell, F.M., Shuler, K., Muir, K.W., and Wardlaw, J.M. (2012) Systematic review of perfusion imaging with computed tomography and magnetic resonance in acute ischemic stroke: heterogeneity of acquisition and postprocessing parameters: a translational medicine research collaboration multicentre acute stroke imaging study. Stroke, 43(2), pp. 563-566. (doi:10.1161/STROKEAHA.111.629923)

McVerry, F., Liebeskind, D.S., and Muir, K.W. (2012) Systematic review of methods for assessing leptomeningeal collateral flow. American Journal of Neuroradiology, 33(3), pp. 576-582. (doi:10.3174/ajnr.A2794)


Rossit, S., Malhotra, P., Muir, K., Reeves, I., Duncan, G., and Harvey, M. (2011) The role of right temporal lobe structures in off-line action: evidence from lesion-behavior mapping in stroke patients. Cerebral Cortex, 21(12), pp. 2751-2761. (doi:10.1093/cercor/bhr073)

Dani, K.A., Thomas, R.G.R., Chappell, F.M., Shuler, K., MacLeod, M.J., Muir, K.W., and Wardlaw, J.M. (2011) Computed tomography and magnetic resonance perfusion imaging in ischemic stroke: definitions and thresholds. Annals of Neurology, 70(3), pp. 384-401. (doi:10.1002/ana.22500)

Kalladka, D., and Muir, K.W. (2011) Stem cell therapy in stroke: designing clinical trials. Neurochemistry International, 59(3), pp. 367-370. (doi:10.1016/j.neuint.2011.03.016)

Robertson, C. A., McCabe, C., Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M., Condon, B., Muir, K. W., Santosh, C., and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi:10.1038/jcbfm.2011.67)

Robertson, C. A., McCabe, C., Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M., Condon, B., Muir, K. W., Santosh, C., and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi:10.1038/jcbfm.2011.66)

MacDougall, N.J.J., McVerry, F., Baird, S., Baird, T., Teasdale, E., and Muir, K.W. (2011) Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis. Stroke, 42(8), pp. 2170-2174. (doi:10.1161/STROKEAHA.111.618777)

MacDougall, N.J.J., and Muir, K. (2011) Hyperglycaemia and infarct size in animal models of middle cerebral artery occlusion: systematic review and meta-analysis. Journal of Cerebral Blood Flow and Metabolism, 31(3), pp. 807-818. (doi:10.1038/jcbfm.2010.210)

Muir, K.W., Sinden, J., Miljan, E., and Dunn, L. (2011) Intracranial delivery of stem cells. Translational Stroke Research, 2(3), pp. 266-271. (doi:10.1007/s12975-011-0095-z)

Nagakane, Y. et al. (2011) EPITHET: Positive Result After Reanalysis Using Baseline Diffusion-Weighted Imaging/Perfusion-Weighted Imaging Co-Registration. Stroke, 42(1), pp. 59-64. (doi:10.1161/STROKEAHA.110.580464)

Puetz, V. et al. (2011) Extent of hypoattenuation on CT angiography source images in Basilar Artery occlusion: prognostic value in the Basilar Artery International Cooperation Study. Stroke, 42(12), pp. 3454-3459. (doi:10.1161/STROKEAHA.111.622175)


Dani, K. A., Santosh, C., Brennan, D., McCabe, C., Holmes, W. M., Condon, B., Hadley, D. M., Macrae, I. M., Shaw, M., and Muir, K. W. (2010) T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Annals of Neurology, 68(1), pp. 37-47. (doi:10.1002/ana.22032)

Crozier, J. E. M., Reid, J., Welch, G., Muir, K.W., and Stuart, W. (2010) Early carotid endarterectomy following thrombolysis in the hyperacute treatment of stroke. British Journal of Surgery, 98(2), pp. 235-238. (doi:10.1002/bjs.7306)

Awadh, M., MacDougall, N., Santosh, C., Teasdale, E., Baird, T., and Muir, K.W. (2010) Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation. Stroke, 41(9), pp. 1990-1995. (doi:10.1161/STROKEAHA.109.569459)

Dani, K.A., and Muir, K.W. (2010) Do iodinated contrast agents impair fibrinolysis in acute stroke? A systematic review. American Journal of Neuroradiology, 31(1), pp. 170-174. (doi:10.3174/ajnr.A1782)

Harvey, M. et al. (2010) Long term improvements in activities of daily living in patients with hemispatial neglect. Behavioural Neurology, 23(4), pp. 237-239. (doi:10.3233/BEN-2010-0304)

McCormick, M., Hadley, D., McLean, J. R., Macfarlane, J. A., Condon, B., and Muir, K. W. (2010) Randomized, Controlled Trial of Insulin for Acute Poststroke Hyperglycemia. Annals of Neurology, 67(5), pp. 570-578. (doi:10.1002/ana.21983)


Rossit, S., Malhotra, P., Muir, K., Reeves, I., Duncan, G., Birschel, P., and Harvey, M. (2009) The neural basis of visuomotor deficits in hemispatial neglect. Neuropsychologia, 47(10), pp. 2149-2153. (doi:10.1016/j.neuropsychologia.2009.04.015)

Rossit, S., Muir, K., Reeves, I., Duncan, G., Birschel, P., and Harvey, M. (2009) Immediate and delayed reaching in hemispatial neglect. Neuropsychologia, 47(6), pp. 1563-1572. (doi:10.1016/j.neuropsychologia.2008.08.008)

Butler, S.H., Rossit, S., Gilchrist, I.D., Ludwig, C.J.H., Olk, B., Muir, K., Reeves, I., and Harvey, M. (2009) Non-lateralised deficits in anti-saccade performance in patients with hemispatial neglect. Neuropsychologia, 47(12), pp. 2488-2495. (doi:10.1016/j.neuropsychologia.2009.04.022)

Dowson, A. et al. (2009) Response to Letter Regarding Article, 'Migraine Intervention With STARFlex Technology (MIST) Trial'. Circulation, 119(5), E194-E194.

Kidwell, C.S., Lees, K.R., Muir, K.W., Chen, C., Davis, S.M., De Silva, D.A., Weir, C.J., Starkman, S., Alger, J.R., and Saver, J.L. (2009) Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial. Stroke, 40(5), pp. 1704-1709. (doi:10.1161/STROKEAHA.108.537613)

Schonewille, W. et al. (2009) Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study. Lancet Neurology, 8(8), pp. 724-730.


Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi:10.1038/jcbfm.2008.56)

Lecrux, C., McCabe, C., Weir, C.J., Gallagher, L., Mullin, J., Touzani, O., Muir, K., Lees, K.R., and Macrae, I.M. (2008) Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats. Stroke, 39(2), pp. 448-454. (doi:10.1161/STROKEAHA.107.492934)

Dani, K.A., McCormick, M.T., and Muir, K.W. (2008) Brain lesion volume and capacity for consent in stroke trials: potential regulatory barriers to the use of surrogate markers. Stroke, 39(8), pp. 2336-2340. (doi:10.1161/STROKEAHA.107.507111)

Davis, S. et al. (2008) Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurology, 7(4), pp. 299-309. (doi:10.1016/S1474-4422(08)70044-9)

Dowson, A. et al. (2008) Migraine intervention with STARFlex technology (MIST) trial - A prospective, multicenter, double-blind, sham-controlled trial to evaluate the effectiveness of patent foramen ovale closure with STARFlex septal repair implant to resolve refractory migraine. Circulation, 117(11), pp. 1397-1404.

Lees, K.R. et al. (2008) Thrombolytic therapy for acute stroke in the United Kingdom: experience from the safe implementation of thrombolysis in stroke (SITS) register. QJM: An International Journal of Medicine, 101(11), pp. 863-869. (doi:10.1093/qjmed/hcn102)

McCormick, M.T., Muir, K.W., Gray, C.S., and Walters, M.R. (2008) Management of hyperglycemia in acute stroke: how, when, and for whom? Stroke, 39(7), pp. 2177-2185. (doi:10.1161/STROKEAHA.107.496646)

McCormick, M.T., Reeves, I., Baird, T., Bone, I., and Muir, K. (2008) Implementation of a stroke thrombolysis service within a tertiary neurosciences centre in the United Kingdom. QJM: An International Journal of Medicine, 101(4), pp. 291-298.

Muir, K.W. (2008) The PREVAIL trial and low-molecular-weight heparin for prevention of venous thromboembolism. Stroke, 39(7), pp. 2174-2176. (doi:10.1161/STROKEAHA.107.509588)

Wahlgren, N., Ahmed, N., Davalos, A., Hacke, W., Millan, M., Muir, K., Roine, R.O., Toni, D., and Lees, K.R. (2008) Thrombolysis with alteplase 3—4·5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet, 372(9646), pp. 1303-1309. (doi:10.1016/S0140-6736(08)61339-2)


Smith, A., Gilchrist, L.D., Butler, S.H., Muir, K., Bone, I., Reeves, I., and Harvey, M. (2007) Non-lateralised deficits of drawing production in hemispatial neglect. Brain and Cognition, 64(2), pp. 150-157. (doi:10.1016/j.bandc.2007.02.001)

Aslanyan, S., Weir, C.J., Muir, K.W., and Lees, K.R. (2007) Magnesium for treatment of acute lacunar stroke syndromes: further analysis of the IMAGES trial. Stroke, 38(10), pp. 1269-1273. (doi:10.1161/01.STR.0000259628.94421.09)

Moreton, F.C., McCormick, M., and Muir, K.W. (2007) Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study. Stroke, 38(2), pp. 407-410. (doi:10.1161/01.STR.0000254487.73282.4d)

Muir, K.W., Baird-Gunning, J., Walker, L., Baird, T., McCormick, M., and Coutts, S.B. (2007) Can the ischemic penumbra be identified on noncontrast CT of acute stroke? Stroke, 38(9), pp. 2485-2490. (doi:10.1161/STROKEAHA.107.484592)

Muir, K., Sattar, N., Tyrrell, P., and Warburton, E. (2007) Inflammation and ischaemic stroke. Current Opinion in Neurology, 20, pp. 334-342.

Murray, S., Bashir, K., Lees, K.R., Langhorne, P., Muir, K., MacAlpine, C., and Roberts, M. (2007) Epidemiological aspects of referral to TIA clinics in Glasgow. Scottish Medical Journal, 52, pp. 4-8.


McCormick, M.T., and Muir, K.W. (2006) Referral bias may underestimate number of very elderly patients eligible for rtPA. Stroke, 37(4), pp. 942-943. (doi:10.1161/01.STR.0000210167.37729.eb)

Baird, T.A., Halbert, H.M., McCormick, M., Muir, K.W., and Teasdale, E. (2006) Visual evaluation of perfusion computed tomography in acute stroke accurately estimates infarct volume and tissue viability. Journal of Neurology, Neurosurgery and Psychiatry, 77, pp. 334-339. (doi:10.1136/jnnp.2005.074179)

Baron, J., Buchan, A., Muir, K., Rother, J., and von, K. (2006) Imaging of acute stroke. Lancet Neurology, 5, pp. 755-768.

Butler, S.H., Gilchrist, I.D., Ludwig, C.J.H., Muir, K., and Harvey, M. (2006) Impairments of oculomotor control in a patient with a right temporo-parietal lesion. Cognitive Neuropsychology, 23(6), pp. 990-999. (doi:10.1080/13594320600768847)

Lees, K., Muir, K., Ovbiagele, B., Saver, J., and Weir, C. (2006) Effect of smoking status on outcome after acute ischemic stroke. Cerebrovascular Diseases, 21, pp. 260-265. (doi:10.1159/000091224)

Muir, K., Razvi, S., Teasdale, E., Tyagi, A., and Walker, L. (2006) Cluster headache due to internal carotid artery dissection. Journal of Neurology, 253(5), pp. 661-663.

Muir, K. (2006) Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists. Current Opinion in Pharmacology, 6, pp. 53-60. (doi:10.1016/j.coph.2005.12.002)


Bone, I., Davidson, R., Muir, K., and Razvi, S.S.M. (2005) The prevalence of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) in the west of Scotland. Journal of Neurology, Neurosurgery and Psychiatry, 76(5), pp. 739-741.

Muir, K.W., and Santosh, C. (2005) Imaging of acute stroke and transient ischaemic attack. Journal of Neurology, Neurosurgery and Psychiatry, 76, pp. 19-28. (doi:10.1136/jnnp.2005.075168)

Muir, K., and Teal, P. (2005) Why have neuroprotectants failed? Lessons learned from stroke trials. Journal of Neurology, 252, pp. 1011-1020. (doi:10.1007/s00415-005-0933-6)

Razvi, S., Davidson, R., Bone, I., and Muir, K. (2005) Is inadequate family history a barrier to diagnosis in CADASIL? Acta Neurologica Scandinavica, 112, pp. 323-326. (doi:10.1111/j.1600-0404.2005.00495.x)

Walters, M., Muir, K., Harbison, J., Lees, K., and Ford, G. (2005) Intravenous thrombolysis for acute ischaemic stroke: Preliminary experience with recombinant tissue plasminogen activator in the UK. Cerebrovascular Diseases, 20, pp. 438-442. (doi:10.1159/000088982)


Baird, T., Bone, I., and Muir, K. (2004) Basilar artery occlusion. Neurocritical Care, 1(3), pp. 319-329.

Lees, K.R. et al. (2004) Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial. Lancet, 363, pp. 439-445.

McGonigal, A., and Muir, K. (2004) Journey of an embolus. Neurology, 62(10), p. 1902.

Muir, K. (2004) Secondary prevention for stroke and transient ischaemic attacks - Even patients with normal blood pressure and cholesterol levels may benefit. British Medical Journal, 328(7435), pp. 297-298.

Muir, K. (2004) Secondary prevention for stroke and transient ischaemic attacks - Horizons needs expanding - PROGRESS is about reducing blood pressure, not promoting drugs - Author's reply. British Medical Journal, 328(7444), p. 897.

Muir, K., and Nazir, F. (2004) Prolonged interval between vertebral artery dissection and ischemic stroke. Neurology, 62(9), pp. 1646-1647.


Al, D.L. et al. (2003) Cluster-randomized, controlled trial of computer-based decision support for selecting long-term anti-thrombotic therapy after acute ischaemic stroke. QJM: An International Journal of Medicine, 96, pp. 143-153. (doi:10.1093/qjmed/hcg019)

Alberts, M., Graffagnino, C., Hoffmann, K., Lees, K., McCarron, M., Muir, K., Nicoll, J., and Weir, C. (2003) Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage. Acta Neurologica Scandinavica, 107, pp. 106-109.

Muir, K., and Lees, K. (2003) Excitatory Amino Acid antagonists for acute stroke. Cochrane Database of Systematic Reviews, 3, CD001244.


Muir, K. (2002) Heterogeneity of stroke pathophysiology and neuroprotective clinical trial design. Stroke, 33(6), pp. 1545-1550.

Muir, K. (2002) Inflammation, blood pressure, and stroke: An opportunity to target primary prevention? Stroke, 33(12), pp. 2732-2733.

Muir, K. (2002) Magnesium in stroke treatment. Postgraduate Medical Journal, 78, pp. 641-645.

Wilson, J., Hareendran, A., Grant, M., Baird, T., Schulz, U., Muir, K., and Bone, I. (2002) Improving the assessment of outcomes in stroke - Use of a structured interview to assign grades on the modified Rankin Scale. Stroke, 33, pp. 2243-2246. (doi:10.1161/01STR000002743722450BD)


Bone, I., Dyker, A., Lees, K., McCarron, M., Muir, K., Nicoll, J., and Weir, C. (2001) Apolipoprotein E genotype, coagulation, and survival following acute stroke. Neurology, 57(6), pp. 1097-1100.

Muir, K. (2001) Headache after diagnostic lumbar puncture - Authors should have used smaller gauge needles - Reply. British Medical Journal, 322(7292), p. 994.

Muir, K. (2001) Medical management of stroke. Journal of Neurology, Neurosurgery and Psychiatry, 70, I12-I16.

Muir, K.W. (2001) Magnesium for neuroprotection in ischaemic stroke - Rationale for use and evidence of effectiveness. CNS Drugs, 15, pp. 921-930.


McCarron, M., Metcalfe, R., and Muir, K. (2000) Facial nerve palsy secondary to internal carotid artery dissection. European Journal of Neurology, 7(6), pp. 723-725.

This list was generated on Wed May 25 23:43:25 2016 BST.
  • The UK7T Network: developing the ultra-high field MRI platform for biomedical research.
    Medical Research Council
    2016 - 2019
  • ATTEST 2: Alteplase-Tenecteplase Thrombolysis Efficacy in Stroke Thrombolysis
    The Stroke Association
    2016 - 2021
  • Postgraduate and Early Career Researcher Exchanges (SINAPSE)
    Scottish Funding Council
    2015 - 2017
  • Pools Engagement in European Research (PEER) (SINAPSE)
    Scottish Funding Council
    2015 - 2017
  • Pragmatic Ischaemic Thrombectomy Evaluation (PISTE) trial: A randomised controlled trial of mechanical thrombectomy in acute ischaemic stroke
    National Institute for Health Research
    2015 - 2019
  • Continued Development of the SINAPSE Network
    Scottish Funding Council
    2015 - 2019
  • Non invasive brain stimulation in stroke patients
    Scottish Executive Health Department
    2014 - 2017
  • Metabolite and protein profiling in CADASIL to unravel the vascular pathophysiology and natural history
    NHS Endowment Funds
    2014 - 2016
  • Pilot MRI Study for the Investigation of Pathophysiology in Intracerebral Haemorrhage
    Academy of Medical Sciences
    2014 - 2015
  • Xanthine oxidase inhibition for improvement of Long-term Outcomes following ischaemic stroke and transient ischaemic attack (XILO-FIST)
    Stroke Association
    2014 - 2019
  • Characterising vascular pathophysiology in CADASIL (cerebral autosomal dominant arteriopathy with subacute infarcts and leukoencephalopathy) by evaluation of gluteal resistance vessels
    The Stroke Association
    2013 - 2016
  • Penumbra and Recanalisation Acute CT in Ischaemic Stroke Evaluation (PRACTISE)
    National Institute for Health Research
    2013 - 2016
  • Cerebral and peripheral perfusion and reactivity in CADASIL: a longitudinal pilot study
    Scottish Executive Health Department
    2013 - 2015
  • Corticospinal reorganisation after experimental stroke.
    Neurosciences Foundation
    2012 - 2013
  • Clinical Research Fellowships
    NHS Greater Glasgow & Clyde
    2012 - 2014
  • Metabolic MRI in Acute Stroke; Development and Validation of the 'Oxygen Challenge' Technique
    Scottish Executive Health Department
    2012 - 2014
  • Supporting the ischaemic brain with oxygen-carrying perfluorocarbons.
    Scottish Executive Health Department
    2012 - 2013
  • Supporting the ischaemic brain with oxygen-carrying perfluorocarbons.
    Scottish Executive Health Department
    2012 - 2014
  • PISTE (Pragmatic Ischaemic Stroke Thrombectomy Evaluation)
    The Stroke Association
    2012 - 2014
    European Commission
    2011 - 2016
  • ATTEST: Pilot trial of Tenecteplase for Acute Ischaemic Stroke
    The Stroke Association
    2011 - 2014
  • Pilot Study of Susceptibility Weighted Imaging Based Oxygen Challenge in Hyperacute Stroke
    Neurosciences Foundation
    2011 - 2013
  • An Assessment of the Cost Effectiveness of Magnetic Resonance Including Diffusion-Weighted Brain Imaging in Patients with Transient Ischaemic Attack and Minor Stroke
    National Institute for Health Research
    2010 - 2012
  • Multimodal Imaging in Acute Ischemic Stroke
    Chest, Heart & Stroke, Scotland
    2010 - 2011
  • SINAPSE-SPIRIT: Novel and collaborative approaches to knowledge exchange in translational imaging
    Scottish Funding Council
    2010 - 2013
  • Metabolic syndrome, hyperglycemia and experimental stroke
    Scottish Executive Health Department
    2009 - 2010
  • Scottish Hyperacute stroke Activity Register and Evaluation: SHARE
    Chest, Heart & Stroke, Scotland
    2009 - 2011
  • Urinary catherterisation of newly diagnosed stroke patients
    NHS Greater Glasgow & Clyde
    2009 - 2010
  • Central adjudication of modified Rankin scale disability assessments in acute stroke trials
    Scottish Executive Health Department
    2009 - 2010
  • Pathophysiological relevance of acute post-stroke hyperglycaemia in relation to brain perfusion and arterial patency
    Stroke Association
    2008 - 2011
  • Imaging the ischaemic penumbra using BOLD MRI with oxygen challenge as a biotracer
    2008 - 2011
  • Magnesium in acute lacunar stroke patients - preliminary exploration of scientific hypothesis and implementation of optimal design procedure
    Scottish Executive Health Department
    2005 - 2006
  • Spectroscopic evaluation of lesion evolution in stroke - trial of insulin for acute lacticacidosis (SELESTIAL)
    The Stroke Association
    2003 - 2006
  • Managed Clinical Network for Stroke Neurology - Evaluation Project
    Lanarkshire NHS Board
    2003 - 2006
  • Managed Clinical Network for Stroke Neurology - Evaluation Project
    Scottish Executive Health Department
    2003 - 2005