PsyRING

Papers

Cochran et al. (2003) Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs.

Egerton et al. (2005) Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia.

Morris et al. (2005) PCP: from pharmacology to modelling schizophrenia.

Egerton et al. (2008)  Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats.

Pratt et al. (2008) Modelling prefrontal cortex deficits in schizoprenia:implications for treatment. 

Winchester et al. (2012) Converging evidence that sequence variations in the novel candidate gene map2k7 (mkk7) are functionally associated with schizophrenia.

Hunter et al. (2012) Negative symptoms and psychosocial functioning in schizophrenia: neglected but important targets for treatment.

Barry et al. (2012) Schizophrenia. BMJ Clinical Evidence [online] 2012

Hunter et al. (2012) Treatment of schizophrenia in the 21st century: towards a more personalized approach. In: Schizophrenia in the 21st Century. Edited by: Dr. T.H.J. Burne.

Pratt, J.A., Winchester, C.L., Dawson, N, and Morris, B.J. (2012) Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap. Nature Reviews Drug Discovery, 22, 560-79       

Morris BJ, & Pratt JA. (2014) Novel treatment strategies for schizophrenia from improved understanding of genetic risk. Clin Genet. 2014 86:401-11. PubMed PMID: 25142969.

Dawson N, McDonald M, Higham DJ, Morris BJ, & Pratt JA.  (2014) Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks. Neuropsychopharmacology. 39:1786-98.  PubMed PMID: 24492765;

Dawson N, Morris BJ, & Pratt JA. (2015 ) Functional brain connectivity phenotypes for schizophrenia drug discovery. J Psychopharmacol. 29:169-77.  PubMed PMID: 25567554.

Pratt, J.A. and Morris, B.J. (2015) The thalamic reticular nucleus: a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery. Journal of Psychopharmacology, 29, 127-137

Posters

Paterson et al (2009) An in vitro model for investigating the role of schizophrenia candidate gene ERBB4

Thompson et al (2009) Modafinil reverses PCP-induced deficits in cognitive flexibility

Winchester et al (2009) Polymorphic variants and differential expression of DPYSL2 in schizophrenia

Hunter et al (2010) Impact of negative symptoms on psychosocial functioning in schizophrenia.

Dawson et al (2010) Subchronic Phencyclidine (PCP) treatment produces schizophrenia-like alterations in functional integration and brain network structure in rats.

Thomson et al (2010) Differential effects of PCP in an effort based reward task and a sucrose preference task.

Neil Dawson et al (2014) Disc1 mutation induced alterations in cerebral metabolism  and in the response to acute subanaesthetic ketamine:  a comparison of three different disc1 mutations. Abstracts of the 4th Biennial Schizophrenia International Research Conference/ Schizophrenia Research 153, Supplement 1 (2014) S1