We always welcome applications for Fellowships, in particular at the Senior level
(e.g. from the Wellcome Trust). We occupy brand new laboratories
and have available space and excellent facilities. We specialize
mainly in trypanosomes and Plasmodium, but would be interested in proposals also to
study other parasites.
In the first instance, please contact Andy Waters
A postdoctoral position is available for 3 years at the Wellcome Trust Centre for Molecular Dr Parasitology, University of Glasgow, Scotland, UK. The post will be joinly held in the labs of Richard McCulloch and Prof Jeremy Mottram, funded by a BBSRC grant, with a salary in the range £26,264 - £36,298.
The post will establish a new project, bringing together the expertise of the host labs, to identify the protein kinases in the African trypanosome Trypanosoma brucei that control DNA replication and repair, fundamental pathways of genome transmission, and to ask if these factors may be considered for their potential in therapeutic intervention. To do this, RNAi and chemical inhibitor screens will be coupled with high-content cell imaging and next generation sequencing. The project benefits from technical and imaging specialist support, and the individual appointed will join established teams studying these areas of parasite biology.
We are seeking a highly motivated and enthusiastic individual with excellent problem solving skills to thrive in a highly supportive environment. The ideal candidate will have expertise in cell biology and molecular biology techniques. Previous experience with protozoan parasites is not essential.
Applicants should submit a letter of interest and CV to Dr McCulloch (Richard.McCulloch@glasgow.ac.uk)
Job Details Software Developer (Programmer/Analyst)
Reference Number 003014
Location Gilmorehill Campus / Main Building
College / Service COLLEGE OF MVLS
Department RI INFECTION IMMUNITY & INFLAMMATION
Job Family Technical And Related
Position Type Full Time
Salary Range £31,948 - £35,938
A biologist with bioinformatics / computer programming experience or a computer scientist with bioinformatics / biology experience to join a large team working on highly visible web resources for trypanosomatids (www.tritrypdb.org). The successful candidate will interface with scientists working in parasitology research to acquire genomics and postgenomics datasets, integrate data into a relational database and present to users in intuitive and informative interfaces. They will work collaboratively on a team of approximately 10 biologists and software developers to translate requirements generated by the scientific user community into effective data representations and interfaces. Participation in the preparation of scientific papers and technical documentation and attendance at scientific meetings are encouraged. The postholder will work closely with colleagues at the Wellcome Trust Sanger Institute, The University of Liverpool and the University of Pennsylvania.
Main Duties and Responsibilities
1. To participate in translation of requirements from biologists to web interfaces.
2. Run analyses and prepare data for loading into relational database.
3. To write queries and data representations for known data types.
4. To develop schema and data integrations, write queries and data representations for new data types.
5. Interact with data providers to make certain data and representations are correct
6. Collaborate with bioinformatics groups in other organisations to influence the development of standards for data formats and systems behaviour where this relates to projects.
7. Contribute to documenting software development results for inclusion in papers, reports, and presentations, and contribute to the preparation of designated parts of such papers, reports and presentations.
8. Contribute to the presentation of work at internal Institute or group seminars and external seminars and/or national and international conferences to enhance the profile of the research group.
9. Assist in the supervision and training of undergraduate or postgraduate students, and/or technical staff where appropriate.
10. Continuing professional development: developing programming and research skills, keeping knowledge up-to-date through attendance at and contributing to conferences and seminars; participating in local research groups to build up networks with other colleagues in the field.
Knowledge, Qualifications, Skills and Experience
A1 BSc in computer science, bioinformatics, biology or related field
B1 PhD in computer science, bioinformatics, biology or related field
C1 An ability to learn quickly on the job
C2 Evidence of having successfully worked in a collaborative, project-focused software team
C3 Good time management skills: ability to prioritise tasks to ensure the right things are done at the right time
C4 Highly developed problem-solving skills
C5 Ability to integrate within an active group involved in the generation, analyses and distribution of genomics and postgenomics data, as well as generating novel informatics technology
D1 A strong interest in this science
E1 4 years' experience in a relevant technical or scientific role
E2 Experience of delivering a quality product within fixed deadlines
E3 Experience with bioinformatics and genomics applications is required.
F1 Prior experience in bioinformatics, data warehousing, statistical analysis (statistical training & experience in using statistical software would be particularly advantageous)
F2 Experience of an MVC framework
F3 Experience of scripting languages such as Perl, Python or Ruby
F4 Experience of statistical computing in R
F5 At least 1 year postdoctoral experience
F6 Experience with and working knowledge of UNIX, Perl, SQL and relational databases and XML .
F7 Experience of web services and XML
F8 Research Experience
Development and implementation of bioinformatics software for genomics and postgenomic data analysis.
Planning and Organising
Reacting to duties assigned by managers.
Effective organisation skills to manage time and prioritise development efforts.
Establishing work timetables to achieve short and long term goals for completion of various stages of the project.
Purchases of technical materials and software.
To gather requirements, to define, design and write programs required for project function, and provide progress updates
To gather requirements and provide progress updates, provide informatics assistance and training
Meet with Institute colleagues to exchange information and ensure efficient working practices
Work with collaborators at The Sanger Institute, University of Liverpool and the University of Pennsylvania to obtain data and discuss approaches to analysis
Other internal and external collaborators as appropriate to exchange ideas and information to enhance the research profile of TritrypDB
Deciding on methods to use as part of the developed bioinformatics pipelines
Assist with learning needs/requirements of students and colleagues
Standard Terms & Conditions
Salary will be on the Technical & Related Grade, level 7, £31,948–£35,938 per annum.
This post is funded for 2 years.
New entrants to the University will be required to serve a probationary period of 6 months.
The successful candidate will be eligible to join the University of Glasgow Pension Scheme (UGPS).