Professor Paul Garside

  • Chair in Basic Immunology (Immunology)
  • Associate - Life Sciences (School of Life Sciences)

telephone: 01413307251
email: Paul.Garside@glasgow.ac.uk

Research interests

Current Research :

The long standing theme of my research has been to investigate the fundamentals of immune regulation in vivo and apply any findings to infectious and autoimmune disease scenarios. A key aspect has been my partnership with Prof Jim Brewer as we have continued to drive innovative approaches to understanding immune responses in vivo. We were amongst the first groups to apply developments in imaging technology to the study of immunological tolerance and provided amongst the earliest demonstrations of the importance of immune system dynamics. Further work on immune priming versus tolerance revolutionised our understanding of the molecular bases of these phenomena and broader impact has been achieved with key publications in inflammatory, infectious and autoimmune disease.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • NanoMATe
    European Commission
    2015 - 2017
     
  • Cytoadherence-mediated pathology in cerebral malaria
    Wellcome Trust
    2015 - 2016
     
  • Integrin-mediated regulation of leukocytes in autoimmunity.
    Arthritis Research UK
    2015 - 2020
     
  • Understanding the mechanism of Ag presentation and interaction of DCs T cells in vivo by ISCOMATRIX vaccines.
    CSL Limited
    2015 - 2015
     
  • The Wellcome Centre for Molecular Parasitology ( Core Support )
    Wellcome Trust
    2014 - 2021
     
  • Genetic Determinants of Trypanotolerance in Humans (ISSF Catalyst)
    Wellcome Trust
    2014 - 2015
     
  • In Situ Nanoparticle Assemblies for Healthcare Diagnostics and Therapy
    Engineering & Physical Sciences Research Council
    2014 - 2018
     
  • Rheumatoid Arthritis Centre of Excellence (RACE - Towards a Cure)
    Arthritis Research UK
    2013 - 2018
     
  • Defining innate and adaptive immune functions of plasmacytoid dendritic cells in atherosclerosis.
    British Heart Foundation
    2013 - 2016
     
  • Defining the Role of Cell Migration in the Initiation and Regulation of Pathogenesis in Inflammatory Arthritis
    Arthritis Research UK
    2013 - 2018
     
  • Understanding the mechanism of Ag presentation and interaction of DCs T cells in vivo by ISCOMATRIX vaccines.
    CSL Limited
    2013 - 2015
     
  • Dissecting differences in joint, tendon sheath and systemic pathology between two murine models of synovial self-tolerance breach: what are the respective roles of T helper-1 and -17 cells?
    Wellcome Trust
    2012 - 2011
     
  • RSE/CRF Biomedical Personal Research Fellowship
    Royal Society of Edinburgh
    2012 - 2012
     
  • Transfer of expertise in bioimaging from academia to industry.
    Scottish Funding Council
    2011 - 2012
     
  • Understanding and manipulating chemokines and their receptors in the context of adjuvants
    BBSRC
    2011 - 2014
     
  • Cytoadherence-mediated pathology in cerebral malaria
    Wellcome Trust
    2011 - 2016
     
  • BTCure
    European Commission
    2011 - 2016
     
  • Gums and Joints
    European Commission
    2010 - 2014
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Wellcome Trust
    2010 - 2010
     
  • Regulation of the adaptive immune response by chemokine scavenging receptors
    MRC
    2010 - 2015
     
  • In Vivo Reporting using Nanosystems Chemistry and Optical Spectroscopy
    EPSRC
    2010 - 2011
     
  • Investigating the role of T cells in vascular pathology
    British Heart Foundation
    2010 - 2010
     
  • Investigating the relationship between the cellular interations in inflamed atricular tissues and their draining lymphoid organs during the development of immune responses
    Arthritis Research UK
    2009 - 2010
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Medical Research Scotland
    2009 - 2010
     
  • Investigating the contributions of inflammation and antigen depot to adjuvant function in vivo
    BBSRC
    2009 - 2010
     
  • International Network in Theoretical Immunology (INTI)
    European Commission
    2009 - 2012
     
  • T cell signalling events in vivo during the induction of immunity and tolerance
    MRC
    2006 - 2009
     
  • Dissecting the roles played by Dendritic cells and T lymphocytes in mediating inflammatory arthropathies
    Scottish Executive Health Department
    2005 - 2008
     
  • Elucidating immune mechanisms in inflammatory arthritis
    The Nuffield Foundation
    2004 - 2013
     
  • Dissection of the Cellular and Molecular Basis of Immunoregulation in Vivo
    MRC
    2004 - 2006
     
  • Pharmaplant - Recombinant Pharmaceuticals from Plants for Human Health
    European Commission
    2004 - 2009
     
  • Revealing the cellular and molecular interactions underlying the development of tolerance or immunity in real time in vivo
    Wellcome Trust
    2003 - 2005
     
  • Dissecting the mechanisms underlying mucosal DNA vaccination
    Wellcome Trust
    2003 - 2005
     
  • Dendritic cell function and immune responsiveness in malaria infections
    Wellcome Trust
    2002 - 2005
     
  • Characterising the role of APC phenotype and activation state in the induction of Th1/Th2 responses in vivo
    BBSRC
    2001 - 2005
     

Publications

List by: Type | Date

Jump to: 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1994
Number of items: 86.

2016

Cosway, E., Anderson, G., Garside, P., and Prendergast, C. (2016) The thymus and rheumatology: should we care? Current Opinion in Rheumatology, 28(2), pp. 189-195. (doi:10.1097/bor.0000000000000251) (PMID:26751840) (PMCID:PMC4732010)

Patakas, A., Ji, R.-R., Weir, W., Connolly, S. E., Benson, R. A., Nadler, S. G., McInnes, I. B., and Garside, P. (2016) Abatacept inhibition of T cell priming in mice by induction of a unique transcriptional profile that reduces their ability to activate antigen-presenting cells. Arthritis and Rheumatism, 68(3), pp. 627-638. (PMID:26473409)

Scales, H. E., Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M., Garside, P., and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi:10.1093/rheumatology/kev361) (PMID:26475798)

2015

Hawkins, P., Armstrong, R., Boden, T., Garside, P., Knight, K., Lilley, E., Seed, M., Wilkinson, M., and Williams, R. O. (2015) Applying refinement to the use of mice and rats in rheumatoid arthritis research. Inflammopharmacology, 23(4), pp. 131-150. (doi:10.1007/s10787-015-0241-4) (PMID:26168847) (PMCID:PMC4508365)

Hu, D. et al. (2015) Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors. Immunity, 42(6), pp. 1100-1115. (doi:10.1016/j.immuni.2015.05.015) (PMID:26084025) (PMCID:PMC4678289)

Oliver-Bell, J., Butcher, J.P., Malcolm, J., Macleod, M.K.L., Adrados Planell, A., Campbell, L., Nibbs, R.J.B., Garside, P., McInnes, I.B., and Culshaw, S. (2015) Periodontitis in the absence of B cells and specific anti-bacterial antibody. Oral Microbiology and Immunology, 30(2), pp. 160-169. (doi:10.1111/omi.12082) (PMID:25219939)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

Benson, R. A., Macleod, M. K.L., Hale, B. G.H., Patakas, A., Garside, P., and Brewer, J. M. (2015) Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo. eLife, 4, e06994. (doi:10.7554/eLife.06994) (PMID:26258879) (PMCID:PMC4558563)

Benson, R. A., McInnes, I. B., Brewer, J. M., and Garside, P. (2015) Cellular imaging in rheumatic diseases. Nature Reviews Rheumatology, 11(6), pp. 357-367. (doi:10.1038/nrrheum.2015.34) (PMID:25800215)

Patakas, A., Ji, R., Weir, W., Connolly, S. E., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) Abatacept inhibits T cell priming by inducing of a unique transcriptional profile that reduces their ability to activate antigen presenting cells. Arthritis and Rheumatology, 68(3), pp. 627-638. (doi:10.1002/art.39470) (PMID:26473409)

2014

Lawton, J. C., Benson, R. A., Garside, P., and Brewer, J. M. (2014) Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections. Parasitology International, 63(1), pp. 165-170. (doi:10.1016/j.parint.2013.07.010)

David, A., Crawford, F., Garside, P., Kappler, J. W., Marrack, P., and Macleod, M. (2014) Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences of the United States of America, 111(21), pp. 7735-7740. (doi:10.1073/pnas.1406218111) (PMID:24821788) (PMCID:PMC4040609)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P., Brewer, J. M., and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi:10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

2013

Grassia, G., MacRitchie, N., Platt, A., Brewer, J., Garside, P., and Maffia, P. (2013) Plasmacytoid dendritic cells: biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi:10.1016/j.pharmthera.2012.10.001) (PMID:23059425)

2012

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356) (PMID:22271449) (PMCID:PMC3398133)

Ghimire, T.R., Benson, R.A., Garside, P., and Brewer, J.M. (2012) Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunology Letters, 147(1-2), pp. 55-62. (doi:10.1016/j.imlet.2012.06.002)

Hutchison, S., Benson, R.A., Gibson, V.B., Pollock, A.H., Garside, P., and Brewer, J.M. (2012) Antigen depot is not required for alum adjuvanticity. FASEB Journal, 26(3), pp. 1272-1279. (doi:10.1096/fj.11-184556)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715) (PMID:23161902) (PMCID:PMC3812864)

Vincent, T.L., Williams, R.O., Maciewicz, R., Silman, A., and Garside, P. (2012) Mapping pathogenesis of arthritis through small animal models. Rheumatology, 51(11), pp. 1931-1941. (doi:10.1093/rheumatology/kes035)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71(1), pp. 80-83. (doi:10.1136/annrheumdis-2011-200348) (PMID:21908454)

2011

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069) (PMID:21570969)

Lee, K. M. et al. (2011) D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood, 118(23), pp. 6220-6229. (doi:10.1182/blood-2011-03-344044)

Butcher, J.P., Malcolm, J., Benson, R.A., Deng, D.M., Brewer, J.M., Garside, P., and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi:10.1177/0022034511412970)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413) (PMID:21506101)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002) (PMID:21419798)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi:10.1161/STROKEAHA.110.603704)

Kollias, G. et al. (2011) Animal models for arthritis: innovative tools for prevention and treatment. Annals of the Rheumatic Diseases, 70(8), pp. 1357-1362. (doi:10.1136/ard.2010.148551)

2010

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311) (PMID:20601593)

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951) (PMID:20421640)

Rush, C.M., Mitchell, T.J., and Garside, P. (2010) A detailed characterisation of the distribution and presentation of DNA vaccine encoded antigen. Vaccine, 28(6), pp. 1620-1634. (doi:10.1016/j.vaccine.2009.11.014)

Ortolano, F., Maffia, P., Dever, G., Millington, O., De Simoni, M., Brewer, J., Bushell, T.J., Garside, P., and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi:10.1111/j.1476-5381.2009.00527.x)

Conigliaro, P., Perricone, C., Benson, R.A., Garside, P., Brewer, J.M., Perricone, R., and Valesini, G. (2010) The type I IFN system in rheumatoid arthritis. Autoimmunity, 43(3), pp. 220-225. (doi:10.3109/08916930903510914)

De Simoni, M.G., Fumagalli, S., Ortolano, F., Maffia, P., Carswell, H.C., and Garside, P. (2010) In vivo blood flow dynamics after focal ischemia in mice. In: International Stroke Conference 2010, San Antonio, TX, 23-26 Feb 2010, e225. (doi:10.1161/01.str.0000366114.11305.66)

Garside, P., and Brewer, J. (2010) In vivo imaging of infection immunology—4I’s! Seminars in Immunopathology, 32(3), pp. 289-296. (doi:10.1007/s00281-010-0215-y)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Millington, O. R., Brewer, J. M., Garside, P., and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi:10.1007/978-1-60761-461-6_13)

2009

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968. (doi:10.4049/jimmunol.182.2.963) (PMID:19124739)

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico, G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

Hueber, A., Stevenson, R., Stokes, R., Graham, D., Garside, P., and McInnes, I. (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42(4), pp. 368-372. (doi:10.1080/08916930902832298) (PMID:19811304)

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116. (doi:10.1111/j.1365-2249.2008.03800.x) (PMID:19076834)

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300) (PMID:18635595)

Rush, C.M., Millington, O.R., Hutchison, S., Bryson, K., Brewer, J.M., and Garside, P. (2009) Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128(4), pp. 463-471. (doi:10.1111/j.1365-2567.2009.03124.x)

2008

Marshall, F. A., Watson, K. A., Garside, P., Harnett, M. M., and Harnett, W. (2008) Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo. Immunology, 123(3), pp. 411-425. (doi:10.1111/j.1365-2567.2007.02706.x)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122. (doi:10.1111/j.1365-2249.2007.03509.x) (PMID:17931392)

2007

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328. (doi:10.1161/CIRCULATIONAHA.106.658492) (PMID:17372180)

Millington, O.R., Gibson, V.B., Rush, C.M., Zinselmeyer, B.H., Phillips, R.S., Garside, P., and Brewer, J.M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathogens, 3(10), e143. (doi:10.1371/journal.ppat.0030143)

2006

Maffia, P., Grassia, G., Di Meglio, P., Carnuccio, R., Berrino, L., Garside, P., Ianaro, A., and Ialenti, A. (2006) Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury. Circulation, 114, pp. 430-437. (doi:10.1161/CIRCULATIONAHA.105.602714) (PMID:16864728)

Millington, O.R., Di Lorenzo, C., Phillips, R., Garside, P., and Brewer, J.M. (2006) Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5(2), pp. 1-22. (doi:dx.doi.org/10.1186/jbiol34)

Duffy, D., Yang, C., Heath, A., Garside, P., and Bell, E. (2006) Naive T-cell receptor transgenic T cells help memory B cells produce antibody. Immunology, 119, pp. 376-384. (doi:10.1111/j.1365-2567.2006.02446.x)

Ierna, M., Scales, H., Schwarz, H., Bunce, C., McIlgorm, A., Garside, P., and Lawrence, C. (2006) OX40 interactions in gastrointestinal nematode infection. Immunology, 117, pp. 108-116. (doi:10.1111/j.1365-2567.2005.02271.x)

Rush, C., Mitchell, T., Burke, B., and Garside, P. (2006) Dissecting the components of the humoral immune response elicited by DNA vaccines. Vaccine, 24, pp. 776-784. (doi:10.1016/j.vaccine.2005.08.080)

Schneider, H., Downey, J., Smith, A., Zinselmeyer, B., Rush, C., Brewer, J., Wei, B., Hogg, N., Garside, P., and Rudd, C. (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313, pp. 1972-1975. (doi:10.1126/science.1131078)

Smith, K., Garside, P., Mcneil, R., and Brewer, J. (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses. Vaccine, 24, pp. 3035-3043. (doi:10.1016/j.vaccine.2005.10.027)

Yang, C., Sparshott, S., Duffy, D., Garside, P., and Bell, E. (2006) The phenotype and survival of antigen-stimulated transgenic CD4 T cells in vivo: the influence of persisting antigen. International Immunology, 18, pp. 515-523. (doi:10.1093/intimm/dxh392)

2005

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007) (PMID:16087401)

Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M., and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi:10.1016/j.jim.2005.04.011)

Kerr, A., Kirkham, L., Kadioglu, A., Andrew, P., Garside, P., Thompson, H., and Mitchell, T. (2005) Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts. Microbes and Infection, 7, pp. 845-852. (doi:10.1016/j.mincinf.2005.02.011)

Marshall, F., Grierson, A., Garside, P., Harnett, W., and Harnett, M. (2005) ES-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific T cells in vivo. Journal of Immunology, 175, pp. 5817-5826.

Mirenda, V., Millington, O., Lechler, R., Scott, D., Hernandez-Fuentes, M., Read, J., Tan, P., George, A., Garside, P., and Marelli-Berg, F. (2005) Tolerant T cells display impaired trafficking ability. European Journal of Immunology, 35, pp. 2146-2156. (doi:10.1002/eji.200425823)

Zinselmeyer, B. H. et al. (2005) In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201(11), pp. 1815-1823. (doi:10.1084/jem.20050203)

Zinselmeyer, B. et al. (2005) In situ characterization of CD4(+) T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201, pp. 1815-1823. (doi:10.1084/jem.20050203)

2004

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I. B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156. (doi:10.4049/jimmunol.173.1.151) (PMID:15210769)

Adams, C., Grierson, A., Mowat, A., Harnett, M., and Garside, P. (2004) Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry. Journal of Immunology, 173, pp. 1579-1586.

Adams, C., Kobets, N., Meiklejohn, G., Millington, O., Grierson, A., Rush, C., Smith, K., and Garside, P. (2004) Tracking lymphocytes in vivo. Archivum Immunologiae et Therapiae Experimentalis, 52, pp. 173-187.

Garside, P., Millington, O., and Smith, K. (2004) The anatomy of mucosal immune responses. Oral Tolerance, 1029, pp. 9-15. (doi:10.1196/annals.1309.002)

Kobets, N., Kennedy, K., O'Donnell, D., and Garside, P. (2004) An investigation of the ability of orally primed and tolerised T cells to help B cells upon mucosal challenge. Immunology, 112, pp. 550-558. (doi:10.1046/j.1365-2567.2004.01913.x)

Millington, O., Mowat, A., and Garside, P. (2004) Induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander T cell population. Journal of Immunology, 173, pp. 6059-6064.

Millington, O., Wei, X., Garside, P., and Mowat, A. (2004) Interleukin-15 is not required for the induction or maintenance of orally induced peripheral tolerance. Immunology, 113, pp. 304-309. (doi:10.1111/j.1365-2567.2004.01965.x)

Scales, H., Ierna, M., Gutierrez-Ramos, J., Coyle, A., Garside, P., and Lawrence, C. (2004) Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. European Journal of Immunology, 34, pp. 2854-2862. (doi:10.1002/eji.200324364)

Smith, K., Brewer, J., Mowat, A., Ron, Y., and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi:10.1111/j.1365-2567.2004.01813.x)

Smith, K., Brewer, J., Rush, C., Riley, J., and Garside, P. (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173, pp. 1640-1646.

2003

Adams, C. L., Macleod, M. K.L., Milner-White, E. J., Aitken, R., Garside, P., and Stott, D.I. (2003) Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology, 108(3), pp. 274-287. (doi:10.1046/j.1365-2567.2003.01583.x) (PMID:12603593)

Eaton, A., Xu, D., and Garside, P. (2003) Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology, 108, pp. 196-203.

Kobets, N., Kennedy, K., and Garside, P. (2003) An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms. Immunology Letters, 88, pp. 147-155. (doi:10.1016/S0165-2478(03)00076-2)

Smith, K., Brewer, J., Webb, P., Coyle, A., Gutierrez-Ramos, C., and Garside, P. (2003) Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Journal of Immunology, 170, pp. 2310-2315.

2002

Rush, C., Mitchell, T., and Garside, P. (2002) Efficient priming of CD4(+) and CD8(+) T cells by DNA vaccination depends on appropriate targeting of sufficient levels of immunologically relevant antigen to appropriate processing pathways. Journal of Immunology, 169, pp. 4951-4960.

Smith, K., Davidson, J., and Garside, P. (2002) T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen although tolerized T cells display a defect in cell division. Immunology, 106, pp. 144-158.

Smith, K., McAskill, F., and Garside, P. (2002) Orally tolerized T cells are only able to enter B cell follicles following challenge with antigen in adjuvant, but they remain unable to provide B cell help. Journal of Immunology, 168, pp. 4318-4325.

2001

Garside, P., and Mowat, A. (2001) Oral tolerance. Seminars in Immunology, 13, pp. 177-185. (doi:10.1006/smim.2001.0310)

2000

Smith, K., Pottage, L., Thomas, E., Leishman, A., Doig, T., Xu, D., Liew, F., and Garside, P. (2000) Th1 and Th2CD4(+) T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. Journal of Immunology, 165(6), pp. 3136-3144.

1994

Taylor-Robinson, A. W., Liew, F. Y., Severn, A., Xu, D., McSorley, S. J., Garside, P., Padron, J., and Phillips, R. S. (1994) Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. European Journal of Immunology, 24(4), pp. 980-984. (doi:10.1002/eji.1830240430) (PMID:8149966)

This list was generated on Thu Sep 29 17:07:59 2016 BST.
Number of items: 86.

Articles

Cosway, E., Anderson, G., Garside, P., and Prendergast, C. (2016) The thymus and rheumatology: should we care? Current Opinion in Rheumatology, 28(2), pp. 189-195. (doi:10.1097/bor.0000000000000251) (PMID:26751840) (PMCID:PMC4732010)

Patakas, A., Ji, R.-R., Weir, W., Connolly, S. E., Benson, R. A., Nadler, S. G., McInnes, I. B., and Garside, P. (2016) Abatacept inhibition of T cell priming in mice by induction of a unique transcriptional profile that reduces their ability to activate antigen-presenting cells. Arthritis and Rheumatism, 68(3), pp. 627-638. (PMID:26473409)

Scales, H. E., Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M., Garside, P., and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi:10.1093/rheumatology/kev361) (PMID:26475798)

Hawkins, P., Armstrong, R., Boden, T., Garside, P., Knight, K., Lilley, E., Seed, M., Wilkinson, M., and Williams, R. O. (2015) Applying refinement to the use of mice and rats in rheumatoid arthritis research. Inflammopharmacology, 23(4), pp. 131-150. (doi:10.1007/s10787-015-0241-4) (PMID:26168847) (PMCID:PMC4508365)

Hu, D. et al. (2015) Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors. Immunity, 42(6), pp. 1100-1115. (doi:10.1016/j.immuni.2015.05.015) (PMID:26084025) (PMCID:PMC4678289)

Oliver-Bell, J., Butcher, J.P., Malcolm, J., Macleod, M.K.L., Adrados Planell, A., Campbell, L., Nibbs, R.J.B., Garside, P., McInnes, I.B., and Culshaw, S. (2015) Periodontitis in the absence of B cells and specific anti-bacterial antibody. Oral Microbiology and Immunology, 30(2), pp. 160-169. (doi:10.1111/omi.12082) (PMID:25219939)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

Benson, R. A., Macleod, M. K.L., Hale, B. G.H., Patakas, A., Garside, P., and Brewer, J. M. (2015) Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo. eLife, 4, e06994. (doi:10.7554/eLife.06994) (PMID:26258879) (PMCID:PMC4558563)

Benson, R. A., McInnes, I. B., Brewer, J. M., and Garside, P. (2015) Cellular imaging in rheumatic diseases. Nature Reviews Rheumatology, 11(6), pp. 357-367. (doi:10.1038/nrrheum.2015.34) (PMID:25800215)

Patakas, A., Ji, R., Weir, W., Connolly, S. E., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) Abatacept inhibits T cell priming by inducing of a unique transcriptional profile that reduces their ability to activate antigen presenting cells. Arthritis and Rheumatology, 68(3), pp. 627-638. (doi:10.1002/art.39470) (PMID:26473409)

Lawton, J. C., Benson, R. A., Garside, P., and Brewer, J. M. (2014) Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections. Parasitology International, 63(1), pp. 165-170. (doi:10.1016/j.parint.2013.07.010)

David, A., Crawford, F., Garside, P., Kappler, J. W., Marrack, P., and Macleod, M. (2014) Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proceedings of the National Academy of Sciences of the United States of America, 111(21), pp. 7735-7740. (doi:10.1073/pnas.1406218111) (PMID:24821788) (PMCID:PMC4040609)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P., Brewer, J. M., and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi:10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

Grassia, G., MacRitchie, N., Platt, A., Brewer, J., Garside, P., and Maffia, P. (2013) Plasmacytoid dendritic cells: biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi:10.1016/j.pharmthera.2012.10.001) (PMID:23059425)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356) (PMID:22271449) (PMCID:PMC3398133)

Ghimire, T.R., Benson, R.A., Garside, P., and Brewer, J.M. (2012) Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunology Letters, 147(1-2), pp. 55-62. (doi:10.1016/j.imlet.2012.06.002)

Hutchison, S., Benson, R.A., Gibson, V.B., Pollock, A.H., Garside, P., and Brewer, J.M. (2012) Antigen depot is not required for alum adjuvanticity. FASEB Journal, 26(3), pp. 1272-1279. (doi:10.1096/fj.11-184556)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715) (PMID:23161902) (PMCID:PMC3812864)

Vincent, T.L., Williams, R.O., Maciewicz, R., Silman, A., and Garside, P. (2012) Mapping pathogenesis of arthritis through small animal models. Rheumatology, 51(11), pp. 1931-1941. (doi:10.1093/rheumatology/kes035)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71(1), pp. 80-83. (doi:10.1136/annrheumdis-2011-200348) (PMID:21908454)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069) (PMID:21570969)

Lee, K. M. et al. (2011) D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood, 118(23), pp. 6220-6229. (doi:10.1182/blood-2011-03-344044)

Butcher, J.P., Malcolm, J., Benson, R.A., Deng, D.M., Brewer, J.M., Garside, P., and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi:10.1177/0022034511412970)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413) (PMID:21506101)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002) (PMID:21419798)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi:10.1161/STROKEAHA.110.603704)

Kollias, G. et al. (2011) Animal models for arthritis: innovative tools for prevention and treatment. Annals of the Rheumatic Diseases, 70(8), pp. 1357-1362. (doi:10.1136/ard.2010.148551)

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311) (PMID:20601593)

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951) (PMID:20421640)

Rush, C.M., Mitchell, T.J., and Garside, P. (2010) A detailed characterisation of the distribution and presentation of DNA vaccine encoded antigen. Vaccine, 28(6), pp. 1620-1634. (doi:10.1016/j.vaccine.2009.11.014)

Ortolano, F., Maffia, P., Dever, G., Millington, O., De Simoni, M., Brewer, J., Bushell, T.J., Garside, P., and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi:10.1111/j.1476-5381.2009.00527.x)

Conigliaro, P., Perricone, C., Benson, R.A., Garside, P., Brewer, J.M., Perricone, R., and Valesini, G. (2010) The type I IFN system in rheumatoid arthritis. Autoimmunity, 43(3), pp. 220-225. (doi:10.3109/08916930903510914)

Garside, P., and Brewer, J. (2010) In vivo imaging of infection immunology—4I’s! Seminars in Immunopathology, 32(3), pp. 289-296. (doi:10.1007/s00281-010-0215-y)

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968. (doi:10.4049/jimmunol.182.2.963) (PMID:19124739)

Hueber, A., Stevenson, R., Stokes, R., Graham, D., Garside, P., and McInnes, I. (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42(4), pp. 368-372. (doi:10.1080/08916930902832298) (PMID:19811304)

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116. (doi:10.1111/j.1365-2249.2008.03800.x) (PMID:19076834)

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300) (PMID:18635595)

Rush, C.M., Millington, O.R., Hutchison, S., Bryson, K., Brewer, J.M., and Garside, P. (2009) Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128(4), pp. 463-471. (doi:10.1111/j.1365-2567.2009.03124.x)

Marshall, F. A., Watson, K. A., Garside, P., Harnett, M. M., and Harnett, W. (2008) Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo. Immunology, 123(3), pp. 411-425. (doi:10.1111/j.1365-2567.2007.02706.x)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122. (doi:10.1111/j.1365-2249.2007.03509.x) (PMID:17931392)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328. (doi:10.1161/CIRCULATIONAHA.106.658492) (PMID:17372180)

Millington, O.R., Gibson, V.B., Rush, C.M., Zinselmeyer, B.H., Phillips, R.S., Garside, P., and Brewer, J.M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathogens, 3(10), e143. (doi:10.1371/journal.ppat.0030143)

Maffia, P., Grassia, G., Di Meglio, P., Carnuccio, R., Berrino, L., Garside, P., Ianaro, A., and Ialenti, A. (2006) Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury. Circulation, 114, pp. 430-437. (doi:10.1161/CIRCULATIONAHA.105.602714) (PMID:16864728)

Millington, O.R., Di Lorenzo, C., Phillips, R., Garside, P., and Brewer, J.M. (2006) Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5(2), pp. 1-22. (doi:dx.doi.org/10.1186/jbiol34)

Duffy, D., Yang, C., Heath, A., Garside, P., and Bell, E. (2006) Naive T-cell receptor transgenic T cells help memory B cells produce antibody. Immunology, 119, pp. 376-384. (doi:10.1111/j.1365-2567.2006.02446.x)

Ierna, M., Scales, H., Schwarz, H., Bunce, C., McIlgorm, A., Garside, P., and Lawrence, C. (2006) OX40 interactions in gastrointestinal nematode infection. Immunology, 117, pp. 108-116. (doi:10.1111/j.1365-2567.2005.02271.x)

Rush, C., Mitchell, T., Burke, B., and Garside, P. (2006) Dissecting the components of the humoral immune response elicited by DNA vaccines. Vaccine, 24, pp. 776-784. (doi:10.1016/j.vaccine.2005.08.080)

Schneider, H., Downey, J., Smith, A., Zinselmeyer, B., Rush, C., Brewer, J., Wei, B., Hogg, N., Garside, P., and Rudd, C. (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313, pp. 1972-1975. (doi:10.1126/science.1131078)

Smith, K., Garside, P., Mcneil, R., and Brewer, J. (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses. Vaccine, 24, pp. 3035-3043. (doi:10.1016/j.vaccine.2005.10.027)

Yang, C., Sparshott, S., Duffy, D., Garside, P., and Bell, E. (2006) The phenotype and survival of antigen-stimulated transgenic CD4 T cells in vivo: the influence of persisting antigen. International Immunology, 18, pp. 515-523. (doi:10.1093/intimm/dxh392)

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007) (PMID:16087401)

Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M., and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi:10.1016/j.jim.2005.04.011)

Kerr, A., Kirkham, L., Kadioglu, A., Andrew, P., Garside, P., Thompson, H., and Mitchell, T. (2005) Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts. Microbes and Infection, 7, pp. 845-852. (doi:10.1016/j.mincinf.2005.02.011)

Marshall, F., Grierson, A., Garside, P., Harnett, W., and Harnett, M. (2005) ES-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific T cells in vivo. Journal of Immunology, 175, pp. 5817-5826.

Mirenda, V., Millington, O., Lechler, R., Scott, D., Hernandez-Fuentes, M., Read, J., Tan, P., George, A., Garside, P., and Marelli-Berg, F. (2005) Tolerant T cells display impaired trafficking ability. European Journal of Immunology, 35, pp. 2146-2156. (doi:10.1002/eji.200425823)

Zinselmeyer, B. H. et al. (2005) In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201(11), pp. 1815-1823. (doi:10.1084/jem.20050203)

Zinselmeyer, B. et al. (2005) In situ characterization of CD4(+) T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201, pp. 1815-1823. (doi:10.1084/jem.20050203)

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I. B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156. (doi:10.4049/jimmunol.173.1.151) (PMID:15210769)

Adams, C., Grierson, A., Mowat, A., Harnett, M., and Garside, P. (2004) Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry. Journal of Immunology, 173, pp. 1579-1586.

Adams, C., Kobets, N., Meiklejohn, G., Millington, O., Grierson, A., Rush, C., Smith, K., and Garside, P. (2004) Tracking lymphocytes in vivo. Archivum Immunologiae et Therapiae Experimentalis, 52, pp. 173-187.

Garside, P., Millington, O., and Smith, K. (2004) The anatomy of mucosal immune responses. Oral Tolerance, 1029, pp. 9-15. (doi:10.1196/annals.1309.002)

Kobets, N., Kennedy, K., O'Donnell, D., and Garside, P. (2004) An investigation of the ability of orally primed and tolerised T cells to help B cells upon mucosal challenge. Immunology, 112, pp. 550-558. (doi:10.1046/j.1365-2567.2004.01913.x)

Millington, O., Mowat, A., and Garside, P. (2004) Induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander T cell population. Journal of Immunology, 173, pp. 6059-6064.

Millington, O., Wei, X., Garside, P., and Mowat, A. (2004) Interleukin-15 is not required for the induction or maintenance of orally induced peripheral tolerance. Immunology, 113, pp. 304-309. (doi:10.1111/j.1365-2567.2004.01965.x)

Scales, H., Ierna, M., Gutierrez-Ramos, J., Coyle, A., Garside, P., and Lawrence, C. (2004) Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. European Journal of Immunology, 34, pp. 2854-2862. (doi:10.1002/eji.200324364)

Smith, K., Brewer, J., Mowat, A., Ron, Y., and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi:10.1111/j.1365-2567.2004.01813.x)

Smith, K., Brewer, J., Rush, C., Riley, J., and Garside, P. (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173, pp. 1640-1646.

Adams, C. L., Macleod, M. K.L., Milner-White, E. J., Aitken, R., Garside, P., and Stott, D.I. (2003) Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology, 108(3), pp. 274-287. (doi:10.1046/j.1365-2567.2003.01583.x) (PMID:12603593)

Eaton, A., Xu, D., and Garside, P. (2003) Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology, 108, pp. 196-203.

Kobets, N., Kennedy, K., and Garside, P. (2003) An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms. Immunology Letters, 88, pp. 147-155. (doi:10.1016/S0165-2478(03)00076-2)

Smith, K., Brewer, J., Webb, P., Coyle, A., Gutierrez-Ramos, C., and Garside, P. (2003) Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Journal of Immunology, 170, pp. 2310-2315.

Rush, C., Mitchell, T., and Garside, P. (2002) Efficient priming of CD4(+) and CD8(+) T cells by DNA vaccination depends on appropriate targeting of sufficient levels of immunologically relevant antigen to appropriate processing pathways. Journal of Immunology, 169, pp. 4951-4960.

Smith, K., Davidson, J., and Garside, P. (2002) T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen although tolerized T cells display a defect in cell division. Immunology, 106, pp. 144-158.

Smith, K., McAskill, F., and Garside, P. (2002) Orally tolerized T cells are only able to enter B cell follicles following challenge with antigen in adjuvant, but they remain unable to provide B cell help. Journal of Immunology, 168, pp. 4318-4325.

Garside, P., and Mowat, A. (2001) Oral tolerance. Seminars in Immunology, 13, pp. 177-185. (doi:10.1006/smim.2001.0310)

Smith, K., Pottage, L., Thomas, E., Leishman, A., Doig, T., Xu, D., Liew, F., and Garside, P. (2000) Th1 and Th2CD4(+) T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. Journal of Immunology, 165(6), pp. 3136-3144.

Taylor-Robinson, A. W., Liew, F. Y., Severn, A., Xu, D., McSorley, S. J., Garside, P., Padron, J., and Phillips, R. S. (1994) Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. European Journal of Immunology, 24(4), pp. 980-984. (doi:10.1002/eji.1830240430) (PMID:8149966)

Book Sections

Millington, O. R., Brewer, J. M., Garside, P., and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi:10.1007/978-1-60761-461-6_13)

Conference Proceedings

De Simoni, M.G., Fumagalli, S., Ortolano, F., Maffia, P., Carswell, H.C., and Garside, P. (2010) In vivo blood flow dynamics after focal ischemia in mice. In: International Stroke Conference 2010, San Antonio, TX, 23-26 Feb 2010, e225. (doi:10.1161/01.str.0000366114.11305.66)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico, G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

This list was generated on Thu Sep 29 17:07:59 2016 BST.