• Chair in Basic Immunology (Infection Immunity and Inflammation Medicine)

telephone: 01413307251
email: Paul.Garside@glasgow.ac.uk

Current Research :

The long standing theme of my research has been to investigate the fundamentals of immune regulation in vivo and apply any findings to infectious and autoimmune disease scenarios. A key aspect has been my partnership with Prof Jim Brewer as we have continued to drive innovative approaches to understanding immune responses in vivo. We were amongst the first groups to apply developments in imaging technology to the study of immunological tolerance and provided amongst the earliest demonstrations of the importance of immune system dynamics. Further work on immune priming versus tolerance revolutionised our understanding of the molecular bases of these phenomena and broader impact has been achieved with key publications in inflammatory, infectious and autoimmune disease.

• RSE/CRF Biomedical Personal Research Fellowship
  Royal Society of Edinburgh
  2012 - 2014
   
• RSE/CRF Biomedical Personal Research Fellowship
  Royal Society of Edinburgh
  2012 - 2014
   
• Understanding and manipulating chemokines and their receptors in the context of adjuvants
  BBSRC
  2011 - 2014
   
• BTCure
  European Commission
  2011 - 2016
   
• BTCure
  European Commission
  2011 - 2016
   
• Gums and Joints
  European Commission
  2010 - 2014
   
• Dissecting differences in joint, tendon sheath and systemic pathology between two murine models of synovial self-tolerance breach: what are the respective roles of T helper-1 and -17 cells?
  Wellcome Trust
  2010 - 2011
   
• Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
  Wellcome Trust
  2010 - 2010
   
• Regulation of the adaptive immune response by chemokine scavenging receptors
  MRC
  2010 - 2015
   
• In Vivo Reporting using Nanosystems Chemistry and Optical Spectroscopy
  EPSRC
  2010 - 2011
   
• Investigating the role of T cells in vascular pathology
  British Heart Foundation
  2010 - 2010
   
• Investigating the relationship between the cellular interations in inflamed atricular tissues and their draining lymphoid organs during the development of immune responses
  Arthritis Research UK
  2009 - 2010
   
• Investigating the contributions of inflammation and antigen depot to adjuvant function in vivo
  BBSRC
  2009 - 2010
   
• Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
  Medical Research Scotland
  2009 - 2010
   
• International Network in Theoretical Immunology (INTI)
  European Commission
  2009 - 2012
   
• T cell signalling events in vivo during the induction of immunity and tolerance
  MRC
  2006 - 2009
   
• Dissecting the roles played by Dendritic cells and T lymphocytes in mediating inflammatory arthropathies
  Scottish Executive Health Department
  2005 - 2008
   
• Elucidating immune mechanisms in inflammatory arthritis
  The Nuffield Foundation
  2004 - 2013
   
• Dissection of the Cellular and Molecular Basis of Immunoregulation in Vivo
  MRC
  2004 - 2006
   
• Pharmaplant - Recombinant Pharmaceuticals from Plants for Human Health
  European Commission
  2004 - 2009
   
• Revealing the cellular and molecular interactions underlying the development of tolerance or immunity in real time in vivo
  Wellcome Trust
  2003 - 2005
   
• Dissecting the mechanisms underlying mucosal DNA vaccination
  Wellcome Trust
  2003 - 2005
   
• Dendritic cell function and immune responsiveness in malaria infections
  Wellcome Trust
  2002 - 2005
   
• Characterising the role of APC phenotype and activation state in the induction of Th1/Th2 responses in vivo
  BBSRC
  2001 - 2005