2013

Grassia, G., Macritchie, N., Platt, A., Brewer, J., Garside, P., and Maffia, P. (2013) Plasmacytoid dendritic cells: Biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137 (2). pp. 172-182. ISSN 0163-7258 (doi:10.1016/j.pharmthera.2012.10.001)

2012

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32 (11). pp. 2569-2579. ISSN 1079-5642 (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119 (11). pp. 2545-2551. ISSN 0006-4971 (doi:10.1182/blood-2011-09-378356)

Ghimire, T.R., Benson, R.A., Garside, P., and Brewer, J.M. (2012) Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunology Letters, 147 (1-2). pp. 55-62. ISSN 0165-2478 (doi:10.1016/j.imlet.2012.06.002)

Hutchison, S., Benson, R.A., Gibson, V.B., Pollock, A.H., Garside, P., and Brewer, J.M. (2012) Antigen depot is not required for alum adjuvanticity. FASEB Journal, 26 (3). pp. 1272-1279. ISSN 0892-6638 (doi:10.1096/fj.11-184556)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84 (14). pp. 5968-5975. ISSN 0003-2700 (doi:10.1021/ac3006445)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Vincent, T.L., Williams, R.O., Maciewicz, R., Silman, A., and Garside, P. (2012) Mapping pathogenesis of arthritis through small animal models. Rheumatology, 51 (11). pp. 1931-1941. ISSN 1462-0324 (doi:10.1093/rheumatology/kes035)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71 (1). pp. 80-83. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200348)

2011

Butcher, J.P., Malcolm, J., Benson, R.A., Deng, D.M., Brewer, J.M., Garside, P., and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90 (10). pp. 1221-1227. ISSN 0022-0345 (doi:10.1177/0022034511412970)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Holmdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! Febs Letters, 585 (23). pp. 2640-3648. ISSN 0014-5793 (doi:10.1016/j.febslet.2011.04.069)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Homdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anti-collagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Fumagalli, S. et al. (2011) In Vivo Real-Time Multiphoton Imaging of T Lymphocytes in the Mouse Brain After Experimental Stroke. Stroke, 42 (5). pp. 1429-1436. ISSN 0039-2499 (doi:10.1161/STROKEAHA.110.603704)

Kollias, G. et al. (2011) Animal models for arthritis: innovative tools for prevention and treatment. Annals of the Rheumatic Diseases, 70 (8). pp. 1357-1362. ISSN 0003-4967 (doi:10.1136/ard.2010.148551)

Lee, K.M. et al. (2011) D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood, 118 (23). pp. 6220-6229. ISSN 0006-4971 (doi:10.1182/blood-2011-03-344044)

Patakas, A., Platt, A.M., Butcher, J.P., Maffia, P., McInnes, I.B., Brewer, J.M., Garside, P., and Benson, R.A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138 (1). pp. 38-46. ISSN 0165-2478 (doi:10.1016/j.imlet.2011.03.002)

2010

Platt, A.M., Gibson, V.B., Patakas, A., Benson, R.A., Nadler, S.G., Brewer, J.M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185 (3). pp. 1558-1567. ISSN 0022-1767 (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184 (11). pp. 6378-6385. ISSN 0022-1767 (doi:10.4049/jimmunol.0903951)

Rush, C.M., Mitchell, T.J., and Garside, P. (2010) A detailed characterisation of the distribution and presentation of DNA vaccine encoded antigen. Vaccine, 28 (6). pp. 1620-1634. ISSN 0264-410X (doi:10.1016/j.vaccine.2009.11.014)

Ortolano, F., Maffia, P., Dever, G., Millington, O., De Simoni, M., Brewer, J., Bushell, T.J., Garside, P., and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159 (4). pp. 808-811. ISSN 0007-1188 (doi:10.1111/j.1476-5381.2009.00527.x)

Conigliaro, P., Perricone, C., Benson, R.A., Garside, P., Brewer, J.M., Perricone, R., and Valesini, G. (2010) The type I IFN system in rheumatoid arthritis. Autoimmunity, 43 (3). pp. 220-225. ISSN 0891-6934 (doi:10.3109/08916930903510914)

De Simoni, M.G., Fumagalli, S., Ortolano, F., Maffia, P., Carswell, H.C., and Garside, P. (2010) In vivo blood flow dynamics after focal ischemia in mice. In: International Stroke Conference 2010, 23-26 Feb 2010 , San Antonio, TX.

Garside, P., and Brewer, J. (2010) In vivo imaging of infection immunology—4I’s! Seminars in Immunopathology, 32 (3). pp. 289-296. ISSN 1863-2297 (doi:10.1007/s00281-010-0215-y)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, 07-08 June 2010, Manchester, UK.

Millington, O., Brewer, J., Garside, P., and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F.M. and Nourshargh, S. (eds.) Methods in Molecular Biology. Series: T-Cell Trafficking: Methods and Protocols, 616 . Humana Press Inc.

2009

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31 (3). 147-150 (4). ISSN 0141-9838 (doi:10.1111/j.1365-3024.2008.01090.x)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182 (2). pp. 963-968. ISSN 0022-1767

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, 02-04 Apr 2009, Oxford, Uk.

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, 29 Apr - 1 May 2009, Washington DC, USA.

Hueber, AJ, Stevenson, RD, Stokes, RJ, Graham, D, Garside, P, and McInnes, I (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42 (4). pp. 368-372.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155 (1). pp. 107-116. ISSN 0009-9104

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68 (6). pp. 1059-1066. ISSN 0003-4967 (doi:10.1136/ard.2008.089300)

Rush, C.M., Millington, O.R., Hutchison, S., Bryson, K., Brewer, J.M., and Garside, P. (2009) Characterization of CD4⁺ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128 (4). pp. 463-471. ISSN 0019-2805 (doi:10.1111/j.1365-2567.2009.03124.x)

2008

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151 (1). pp. 114-122. ISSN 0009-9104

Marshall, F.A., Watson, K.A., Garside, P., Harnett, M., and Harnett, W. (2008) Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo. Immunology, 123 (3). pp. 411-425. ISSN 0019-2805 (doi:10.1111/j.1365-2567.2007.02706.x)

2007

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). E326-E328.

Millington, O.R., Gibson, V.B., Rush, C.M., Zinselmeyer, B.H., Phillips, R.S., Garside, P., and Brewer, J.M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathogens, 3 (10). e143. ISSN 1553-7366 (doi:10.1371/journal.ppat.0030143)

2006

Millington, O.R., Di Lorenzo, C., Phillips, R., Garside, P., and Brewer, J.M. (2006) Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5 (2). pp. 1-22. (doi:dx.doi.org/10.1186/jbiol34)

Duffy, D, Yang, CP, Heath, A, Garside, P, and Bell, EB (2006) Naive T-cell receptor transgenic T cells help memory B cells produce antibody. Immunology, 119 . pp. 376-384. (doi:10.1111/j.1365-2567.2006.02446.x)

Ierna, MX, Scales, HE, Schwarz, H, Bunce, C, McIlgorm, A, Garside, P, and Lawrence, CE (2006) OX40 interactions in gastrointestinal nematode infection. Immunology, 117 . pp. 108-116. (doi:10.1111/j.1365-2567.2005.02271.x)

Maffia, P, Grassia, G, Di Meglio, P, Carnuccio, R, Berrino, L, Garside, P, Ianaro, A, and Ialenti, A (2006) Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury. Circulation, 114 . pp. 430-437. (doi:10.1161/CIRCULATIONAHA.105.602714)

Rush, CM, Mitchell, TJ, Burke, B, and Garside, P (2006) Dissecting the components of the humoral immune response elicited by DNA vaccines. Vaccine, 24 . pp. 776-784. ISSN 0264-410X (doi:10.1016/j.vaccine.2005.08.080)

Schneider, H, Downey, J, Smith, A, Zinselmeyer, BH, Rush, C, Brewer, JM, Wei, B, Hogg, N, Garside, P, and Rudd, CE (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313 . pp. 1972-1975. ISSN 0036-8075 (doi:10.1126/science.1131078)

Smith, KM, Garside, P, Mcneil, RC, and Brewer, JM (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses. Vaccine, 24 . pp. 3035-3043. ISSN 0264-410X (doi:10.1016/j.vaccine.2005.10.027)

Yang, CP, Sparshott, SM, Duffy, D, Garside, P, and Bell, EB (2006) The phenotype and survival of antigen-stimulated transgenic CD4 T cells in vivo: the influence of persisting antigen. International Immunology, 18 . pp. 515-523. (doi:10.1093/intimm/dxh392)

2005

Choo-Kang, BSW, Hutchison, S, Nickdel, MB, Bundick, RV, Leishman, AJ, Brewer, JM, McInnes, IB, and Garside, P (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26 . pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Grierson, AM, Mitchell, P, Adams, CL, Mowat, AM, Brewer, JM, Harnett, MM, and Garside, P (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301 . pp. 140-153. (doi:10.1016/j.jim.2005.04.011)

Kerr, AR, Kirkham, LAS, Kadioglu, A, Andrew, PW, Garside, P, Thompson, H, and Mitchell, TJ (2005) Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts. Microbes and Infection, 7 . pp. 845-852. (doi:10.1016/j.mincinf.2005.02.011)

Marshall, FA, Grierson, AM, Garside, P, Harnett, W, and Harnett, MM (2005) ES-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific T cells in vivo. Journal of Immunology, 175 . pp. 5817-5826.

Mirenda, V, Millington, O, Lechler, RI, Scott, D, Hernandez-Fuentes, MP, Read, J, Tan, PH, George, AJT, Garside, P, and Marelli-Berg, FM (2005) Tolerant T cells display impaired trafficking ability. European Journal of Immunology, 35 . pp. 2146-2156. (doi:10.1002/eji.200425823)

Zinselmeyer, B. H. et al. (2005) In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201 (11). pp. 1815-1823. ISSN 0022-1007 (doi:10.1084/jem.20050203)

Zinselmeyer, BH et al. (2005) In situ characterization of CD4(+) T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201 . pp. 1815-1823. (doi:10.1084/jem.20050203)

2004

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173 (1). pp. 151-156. ISSN 0022-1767

Adams, CL, Grierson, AM, Mowat, AM, Harnett, MM, and Garside, P (2004) Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry. Journal of Immunology, 173 . pp. 1579-1586.

Adams, CL, Kobets, N, Meiklejohn, GR, Millington, OR, Grierson, AM, Rush, CM, Smith, KM, and Garside, P (2004) Tracking lymphocytes in vivo. Archivum Immunologiae et Therapiae Experimentalis, 52 . pp. 173-187.

Garside, P, Millington, O, and Smith, KM (2004) The anatomy of mucosal immune responses. Oral Tolerance, 1029 . pp. 9-15. (doi:10.1196/annals.1309.002)

Kobets, N, Kennedy, K, O'Donnell, D, and Garside, P (2004) An investigation of the ability of orally primed and tolerised T cells to help B cells upon mucosal challenge. Immunology, 112 . pp. 550-558. (doi:10.1046/j.1365-2567.2004.01913.x)

Maffia, P, Brewer, JM, Gracie, JA, Ianaro, A, Leung, BP, Mitchell, PJ, Smith, KM, McInnes, LB, and Garside, P (2004) Inducing experimental arthritis and breaking self-tolerance, to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173 . pp. 151-156.

Millington, OR, Mowat, AM, and Garside, P (2004) Induction of bystander suppression by feeding antigen occurs despite normal clonal expansion of the bystander T cell population. Journal of Immunology, 173 . pp. 6059-6064.

Millington, OR, Wei, XQ, Garside, P, and Mowat, AMI (2004) Interleukin-15 is not required for the induction or maintenance of orally induced peripheral tolerance. Immunology, 113 . pp. 304-309. (doi:10.1111/j.1365-2567.2004.01965.x)

Scales, HE, Ierna, MX, Gutierrez-Ramos, JC, Coyle, AJ, Garside, P, and Lawrence, CE (2004) Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. European Journal of Immunology, 34 . pp. 2854-2862. (doi:10.1002/eji.200324364)

Smith, KM, Brewer, JM, Mowat, AM, Ron, Y, and Garside, P (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111 . pp. 248-251. (doi:10.1111/j.1365-2567.2004.01813.x)

Smith, KM, Brewer, JM, Rush, CM, Riley, J, and Garside, P (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173 . pp. 1640-1646.

2003

Adams, C.L., MacLeod, M.K.L., Milner-White, E.J., Aitken, R., Garside, P., and Stott, D.I. (2003) Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology, 108 (3). pp. 247-287.

Eaton, AD, Xu, DM, and Garside, P (2003) Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology, 108 . pp. 196-203.

Kobets, N, Kennedy, K, and Garside, P (2003) An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms. Immunology Letters, 88 . pp. 147-155. (doi:10.1016/S0165-2478(03)00076-2)

Smith, KM, Brewer, JM, Webb, P, Coyle, AJ, Gutierrez-Ramos, C, and Garside, P (2003) Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Journal of Immunology, 170 . pp. 2310-2315.

2002

Rush, C, Mitchell, T, and Garside, P (2002) Efficient priming of CD4(+) and CD8(+) T cells by DNA vaccination depends on appropriate targeting of sufficient levels of immunologically relevant antigen to appropriate processing pathways. Journal of Immunology, 169 . pp. 4951-4960.

Smith, KM, Davidson, JM, and Garside, P (2002) T-cell activation occurs simultaneously in local and peripheral lymphoid tissue following oral administration of a range of doses of immunogenic or tolerogenic antigen although tolerized T cells display a defect in cell division. Immunology, 106 . pp. 144-158.

Smith, KM, McAskill, F, and Garside, P (2002) Orally tolerized T cells are only able to enter B cell follicles following challenge with antigen in adjuvant, but they remain unable to provide B cell help. Journal of Immunology, 168 . pp. 4318-4325.

2001

Garside, P, and Mowat, AM (2001) Oral tolerance. Seminars in Immunology, 13 . pp. 177-185. (doi:10.1006/smim.2001.0310)

2000

Smith, KM, Pottage, L, Thomas, ER, Leishman, AJ, Doig, TN, Xu, DM, Liew, FY, and Garside, P (2000) Th1 and Th2CD4(+) T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo. Journal of Immunology, 165 (6). pp. 3136-3144.