Professor James Brewer

  • Chair in Basic Immunology (Immunology)
  • Associate - Life Sciences (School of Life Sciences)

telephone: 01413308417
email: James.Brewer@glasgow.ac.uk

Biography

Professor Jim Brewer completed a PhD at Strathycle University in 1993, working with Prof. Jim Alexander in the design of novel vaccine adjuvants, and continued to work on the development and formulation of novel adjuvants for industry until 1996. He joined the University of Glasgow’s Immunology Department in 1997 as a Wellcome Career Development Fellow, which allowed him to focus on the fundamental immunological problem of how adjuvants work. During this period he spent time working at Washington University in St. Louis with Dr David Russell, where he developed an interest in the application of microscopy and bioimaging to answer fundamental immunological problems. He was appointed Lecturer at the University of Glasgow in 2001 and Senior Lecturer in 2005.

In 2006, Prof Brewer joined Centre for Biophotonics at the University of Strathclyde as a Reader. Here he established systems to study in vivo, and in real time, cellular interactions during the initiation of immune responses using multiphoton microscopy.

Returning to the University of Glasgow, Professor Brewer joined the Institute of Infection, Immunity and Inflammation as Professor in 2009, and currently holds the Chair in Basic Immunology.

Research interests

Current Research:

Imaging Host & Parasite responses in vivo.

Much of what we understand about the anatomy and architecture of the immune system was revealed through exquisite experiments performed in the 1950’s to 70’s. These studies identified the role that anatomy played in a number of fundamental immunological phenomena including recirculation, induction of immune priming or tolerance and the interactions of T and B cells.

The recent resurgence of interest in the role of immune architecture and anatomy in basic immunological and infectious phenomena is almost entirely due to technological developments in identifying and tracking cells and parasites in vivo, not least through the ability to do this dynamically, in real time through the application of multiphoton microscopy. We have recently established a state of the art, multiphoton microscope system at the University of Glasgow, which allows us to image on more channels, faster and deeper than previously possible.

Our current studies apply multiphoton and other in vivo approaches to analyse immune priming and tolerance, including studies in the context of Plasmodium and Trypanosome infection. This work provides a visual insight into host/parasite interactions and highlight the importance of early cellular dialogue in the development of adaptive immune responses. We also collaborate with physicists, mathematicians and chemists to continue development of new non-invasive, translational cell-imaging approaches.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Implanted imaging laboratories for deep-tissue in vivo imaging
    National Centre for Replacement,Refinement and Reduction of
    2015 - 2017
     
  • Understanding the mechanism of Ag presentation and interaction of DCs T cells in vivo by ISCOMATRIX vaccines.
    CSL Limited
    2015 - 2015
     
  • The Wellcome Centre for Molecular Parasitology ( Core Support )
    Wellcome Trust
    2014 - 2021
     
  • Functional Genomic Studies of PTPN22 in Mouse Models of Arthritis Arthitis Research UK Grant reference: 20505
    Arthritis Research UK
    2014 - 2019
     
  • Defining innate and adaptive immune functions of plasmacytoid dendritic cells in atherosclerosis.
    British Heart Foundation
    2013 - 2016
     
  • Defining the Role of Cell Migration in the Initiation and Regulation of Pathogenesis in Inflammatory Arthritis
    Arthritis Research UK
    2013 - 2018
     
  • Understanding the mechanism of Ag presentation and interaction of DCs T cells in vivo by ISCOMATRIX vaccines.
    CSL Limited
    2013 - 2015
     
  • Imaging immune cells in lung in order to understand asthma
    Asthma-UK
    2012 - 2012
     
  • Transfer of expertise in bioimaging from academia to industry.
    Scottish Funding Council
    2011 - 2012
     
  • Understanding and manipulating chemokines and their receptors in the context of adjuvants
    BBSRC
    2011 - 2014
     
  • Cytoadherence-mediated pathology in cerebral malaria
    Wellcome Trust
    2011 - 2016
     
  • BTCure
    European Commission
    2011 - 2016
     
  • Targeting cell contact to reduce autoimmunity and enhance vaccination
    Scottish Universities Life Sciences Alliance
    2011 - 2012
     
  • In Vivo Reporting using Nanosystems Chemistry and Optical Spectroscopy
    EPSRC
    2010 - 2011
     
  • Defining the parasitological and immunological basis of cerebral pathology during murine experimental cerebral malaria
    MRC
    2010 - 2012
     
  • Visualising antigen presentation in mouse models of atherosclerosis
    Medical Research Scotland
    2010 - 2012
     
  • Investigating the role of T cells in vascular pathology
    British Heart Foundation
    2010 - 2010
     
  • In vivo imaging models of African trypanosomiasis to support drug discovery programmes.
    Gates Foundation
    2010 - 2012
     
  • Investigating the contributions of antigen targeting and inflammation to adjuvant function
    Wellcome Trust
    2009 - 2012
     
  • Dissecting the adaptive immune response to cariogenic bacteria in the oral cavity
    Medical Research Scotland
    2009 - 2010
     
  • Investigating the contributions of inflammation and antigen depot to adjuvant function in vivo
    BBSRC
    2009 - 2010
     
  • International Network in Theoretical Immunology (INTI)
    European Commission
    2009 - 2012
     
  • Dissecting the roles played by Dendritic cells and T lymphocytes in mediating inflammatory arthropathies
    Scottish Executive Health Department
    2005 - 2008
     
  • Analysis of the role of cholestrol-sensitive domains in the trafficking and neurotoxicity of prions
    Tenovus-Scotland
    2004 - 2005
     
  • Elucidating immune mechanisms in inflammatory arthritis
    The Nuffield Foundation
    2004 - 2013
     
  • Revealing the cellular and molecular interactions underlying the development of tolerance or immunity in real time in vivo
    Wellcome Trust
    2003 - 2005
     
  • Dendritic cell function and immune responsiveness in malaria infections
    Wellcome Trust
    2002 - 2005
     
  • Characterising the role of APC phenotype and activation state in the induction of Th1/Th2 responses in vivo
    BBSRC
    2001 - 2005
     

Publications

List by: Type | Date

Jump to: 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001
Number of items: 69.

2015

Coles, J. A., Myburgh, E., Ritchie, R., Hamilton, A., Rodgers, J., Mottram, J. C., Barrett, M. P., and Brewer, J. M. (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi:10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

2014

Oliphant, C. J. et al. (2014) MHCII-mediated dialog between group 2 innate lymphoid cells and CD4+ T cells potentiates type 2 immunity and promotes parasitic helminth expulsion. Immunity, 41(2), pp. 283-295. (doi:10.1016/j.immuni.2014.06.016)

Benson, R. A., Brewer, J. M., and Platt, A. M. (2014) Mechanisms of autoimmunity in human diseases: a critical review of current dogma. Current Opinion in Rheumatology, 26(2), pp. 197-203. (doi:10.1097/BOR.0000000000000037)

Lawton, J. C., Benson, R. A., Garside, P., and Brewer, J. M. (2014) Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections. Parasitology International, 63(1), pp. 165-170. (doi:10.1016/j.parint.2013.07.010)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P., Brewer, J. M., and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi:10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

Shrestha, R., Millington, O., Brewer, J., Dev, K. K., and Bushell, T. J. (2014) Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways. Neuropharmacology, 76, pp. 184-193. (doi:10.1016/j.neuropharm.2013.06.025)

2013

Grassia, G., Macritchie, N., Platt, A., Brewer, J., Garside, P., and Maffia, P. (2013) Plasmacytoid dendritic cells: Biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi:10.1016/j.pharmthera.2012.10.001)

Myburgh, E., Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J., Taylor, M., Barrett, M., Brewer, J., and Mottram, J.C. (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi:10.1371/journal.pntd.0002384)

Stevenson, R. et al. (2013) Analysis of intracellular enzyme activity by surface enhanced Raman scattering. Analyst, 138(21), pp. 6331-6336. (doi:10.1039/c3an00729d)

2012

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Akbar, M., Fraser, A. R., Graham, G. J., Brewer, J. M., and Grant, M. H. (2012) Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model. Journal of The Royal Society Interface, 9(74), pp. 2109-2119. (doi:10.1098/rsif.2012.0006)

Elmesmari, A., Gilchrist, D., Fraser, A., Brewer, J., McInnes, I., and Kurowska-Stolarska, M. (2012) The role of miR-155 in monocyte migration in Rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, pp. 588-589. (doi:10.1111/imm.12002)

Afolaranmi, G.A., Akbar, M., Brewer, J., and Grant, M.H. (2012) Distribution of metal released from cobalt-chromium alloy orthopaedic wear particles implanted into air pouches in mice. Journal of Biomedical Materials Research Part A, 100A(6), pp. 1529-1538. (doi:10.1002/jbm.a.34091)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356)

Elmesmari, A., Gilchrist, D. S., Fraser, A. D., Vaughan, D., McQueenie, R., Graham, G., Brewer, J., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Microrna-155 regulates chemokines and chemokine receptors in Rheumatoid Arthritis monocyte. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S384. (doi:10.1002/art.37735)

Ghimire, T.R., Benson, R.A., Garside, P., and Brewer, J.M. (2012) Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunology Letters, 147(1-2), pp. 55-62. (doi:10.1016/j.imlet.2012.06.002)

Hutchison, S., Benson, R.A., Gibson, V.B., Pollock, A.H., Garside, P., and Brewer, J.M. (2012) Antigen depot is not required for alum adjuvanticity. FASEB Journal, 26(3), pp. 1272-1279. (doi:10.1096/fj.11-184556)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

2011

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069)

Butcher, J.P., Malcolm, J., Benson, R.A., Deng, D.M., Brewer, J.M., Garside, P., and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi:10.1177/0022034511412970)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413) (PMID:21506101)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002)

Akbar, M., Brewer, J.M., and Grant, M.H. (2011) Effect of chromium and cobalt ions on primary human lymphocytesin vitro. Journal of Immunotoxicology, 8(2), pp. 140-149. (doi:10.3109/1547691X.2011.553845)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi:10.1161/STROKEAHA.110.603704)

2010

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951)

Ortolano, F., Maffia, P., Dever, G., Millington, O., De Simoni, M., Brewer, J., Bushell, T.J., Garside, P., and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi:10.1111/j.1476-5381.2009.00527.x)

Conigliaro, P., Perricone, C., Benson, R.A., Garside, P., Brewer, J.M., Perricone, R., and Valesini, G. (2010) The type I IFN system in rheumatoid arthritis. Autoimmunity, 43(3), pp. 220-225. (doi:10.3109/08916930903510914)

Garside, P., and Brewer, J. (2010) In vivo imaging of infection immunology—4I’s! Seminars in Immunopathology, 32(3), pp. 289-296. (doi:10.1007/s00281-010-0215-y)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Millington, O. R., Brewer, J. M., Garside, P., and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi:10.1007/978-1-60761-461-6_13)

Rush, C.M., and Brewer, J.M. (2010) Tracking dendritic cells in vivo. Methods in Molecular Biology, 626, pp. 169-185. (doi:10.1007/978-1-60761-585-9_12)

2009

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968.

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300)

Rush, C.M., Millington, O.R., Hutchison, S., Bryson, K., Brewer, J.M., and Garside, P. (2009) Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128(4), pp. 463-471. (doi:10.1111/j.1365-2567.2009.03124.x)

2008

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi:10.1016/j.imlet.2008.02.008)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122.

2007

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328.

Millington, O.R., Gibson, V.B., Rush, C.M., Zinselmeyer, B.H., Phillips, R.S., Garside, P., and Brewer, J.M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathogens, 3(10), e143. (doi:10.1371/journal.ppat.0030143)

Trif, M., Roseanu, A., Brock, J.H., and Brewer, J.M. (2007) Designing lipid nanostructures for local delivery of biologically active macromolecules. Journal of Liposome Research, 17(3-4), pp. 237-248. (doi:10.1080/08982100701530027)

2006

Millington, O.R., Di Lorenzo, C., Phillips, R., Garside, P., and Brewer, J.M. (2006) Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5(2), pp. 1-22. (doi:dx.doi.org/10.1186/jbiol34)

Brewer, J. (2006) (How) do aluminium adjuvants work? Immunology Letters, 102, pp. 10-15. (doi:10.1016/j.imlet.2005.08.002)

McDonald, F., Mohrs, M., and Brewer, J. (2006) Using bicistronic IL-4 reporter mice to identify IL-4 expressing cells following immunisation with aluminium adjuvant. Vaccine, 24, pp. 5393-5399. (doi:10.1016/j.vaccine.2006.03.049)

Schneider, H., Downey, J., Smith, A., Zinselmeyer, B., Rush, C., Brewer, J., Wei, B., Hogg, N., Garside, P., and Rudd, C. (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313, pp. 1972-1975. (doi:10.1126/science.1131078)

Smith, K., Garside, P., Mcneil, R., and Brewer, J. (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses. Vaccine, 24, pp. 3035-3043. (doi:10.1016/j.vaccine.2005.10.027)

2005

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M., and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi:10.1016/j.jim.2005.04.011)

Zinselmeyer, B. H. et al. (2005) In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201(11), pp. 1815-1823. (doi:10.1084/jem.20050203)

Zinselmeyer, B. et al. (2005) In situ characterization of CD4(+) T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201, pp. 1815-1823. (doi:10.1084/jem.20050203)

2004

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156.

Brewer, J., Pollock, K., Tetley, L., and Russell, D. (2004) Vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles. Journal of Immunology, 173, pp. 6143-6150.

Maffia, P., Brewer, J., Gracie, J., Ianaro, A., Leung, B., Mitchell, P., Smith, K., McInnes, L., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance, to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173, pp. 151-156.

Smith, K., Brewer, J., Mowat, A., Ron, Y., and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi:10.1111/j.1365-2567.2004.01813.x)

Smith, K., Brewer, J., Rush, C., Riley, J., and Garside, P. (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173, pp. 1640-1646.

Wei, X., Niedbala, W., Xu, D., Luo, Z., Pollock, K., and Brewer, J. (2004) Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection. Immunology Letters, 94, pp. 35-37. (doi:10.1016/j.imlet.2004.04.001)

2003

Pollock, K., Conacher, M., Wei, X., Alexander, J., and Brewer, J. (2003) Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12. Immunology, 108, pp. 137-143.

Pollock, K., Mcneil, K., Mottram, J., Lyons, R., Brewer, J., Scott, P., Coombs, G., and Alexander, J. (2003) The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses. Journal of Immunology, 170, pp. 1746-1753.

Smith, K., Brewer, J., Webb, P., Coyle, A., Gutierrez-Ramos, C., and Garside, P. (2003) Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Journal of Immunology, 170, pp. 2310-2315.

Sun, H., Pollock, K., and Brewer, J. (2003) Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro. Vaccine, 21, pp. 849-855.

2002

Leung, B., Conacher, M., Hunter, D., McInnes, I., Liew, F., and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077.

2001

Conacher, M., Alexander, J., and Brewer, J. (2001) Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes). Vaccine, 19, pp. 2965-2974.

Trif, M., Guillen, C., Vaughan, D.M., Telfer, J.M., Brewer, J.M., Roseanu, A., and Brock, J.M. (2001) Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases. Experimental Biology and Medicine, 226(6), pp. 559-564.

This list was generated on Sat Jul 4 14:31:13 2015 BST.
Number of items: 69.

Articles

Coles, J. A., Myburgh, E., Ritchie, R., Hamilton, A., Rodgers, J., Mottram, J. C., Barrett, M. P., and Brewer, J. M. (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi:10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

Oliphant, C. J. et al. (2014) MHCII-mediated dialog between group 2 innate lymphoid cells and CD4+ T cells potentiates type 2 immunity and promotes parasitic helminth expulsion. Immunity, 41(2), pp. 283-295. (doi:10.1016/j.immuni.2014.06.016)

Benson, R. A., Brewer, J. M., and Platt, A. M. (2014) Mechanisms of autoimmunity in human diseases: a critical review of current dogma. Current Opinion in Rheumatology, 26(2), pp. 197-203. (doi:10.1097/BOR.0000000000000037)

Lawton, J. C., Benson, R. A., Garside, P., and Brewer, J. M. (2014) Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections. Parasitology International, 63(1), pp. 165-170. (doi:10.1016/j.parint.2013.07.010)

Maddaluno, M., MacRitchie, N., Grassia, G., Ialenti, A., Butcher, J. P., Garside, P., Brewer, J. M., and Maffia, P. (2014) Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. BioMed Research International(949845), (doi:10.1155/2014/949845) (PMID:25136640) (PMCID:PMC4127268)

Shrestha, R., Millington, O., Brewer, J., Dev, K. K., and Bushell, T. J. (2014) Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways. Neuropharmacology, 76, pp. 184-193. (doi:10.1016/j.neuropharm.2013.06.025)

Grassia, G., Macritchie, N., Platt, A., Brewer, J., Garside, P., and Maffia, P. (2013) Plasmacytoid dendritic cells: Biomarkers or potential therapeutic targets in atherosclerosis? Pharmacology and Therapeutics, 137(2), pp. 172-182. (doi:10.1016/j.pharmthera.2012.10.001)

Myburgh, E., Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J., Taylor, M., Barrett, M., Brewer, J., and Mottram, J.C. (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi:10.1371/journal.pntd.0002384)

Stevenson, R. et al. (2013) Analysis of intracellular enzyme activity by surface enhanced Raman scattering. Analyst, 138(21), pp. 6331-6336. (doi:10.1039/c3an00729d)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Akbar, M., Fraser, A. R., Graham, G. J., Brewer, J. M., and Grant, M. H. (2012) Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model. Journal of The Royal Society Interface, 9(74), pp. 2109-2119. (doi:10.1098/rsif.2012.0006)

Afolaranmi, G.A., Akbar, M., Brewer, J., and Grant, M.H. (2012) Distribution of metal released from cobalt-chromium alloy orthopaedic wear particles implanted into air pouches in mice. Journal of Biomedical Materials Research Part A, 100A(6), pp. 1529-1538. (doi:10.1002/jbm.a.34091)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356)

Ghimire, T.R., Benson, R.A., Garside, P., and Brewer, J.M. (2012) Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunology Letters, 147(1-2), pp. 55-62. (doi:10.1016/j.imlet.2012.06.002)

Hutchison, S., Benson, R.A., Gibson, V.B., Pollock, A.H., Garside, P., and Brewer, J.M. (2012) Antigen depot is not required for alum adjuvanticity. FASEB Journal, 26(3), pp. 1272-1279. (doi:10.1096/fj.11-184556)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069)

Butcher, J.P., Malcolm, J., Benson, R.A., Deng, D.M., Brewer, J.M., Garside, P., and Culshaw, S. (2011) Effects of streptococcus mutans on dendritic cell activation and function. Journal of Dental Research, 90(10), pp. 1221-1227. (doi:10.1177/0022034511412970)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413) (PMID:21506101)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002)

Akbar, M., Brewer, J.M., and Grant, M.H. (2011) Effect of chromium and cobalt ions on primary human lymphocytesin vitro. Journal of Immunotoxicology, 8(2), pp. 140-149. (doi:10.3109/1547691X.2011.553845)

Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi:10.1161/STROKEAHA.110.603704)

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951)

Ortolano, F., Maffia, P., Dever, G., Millington, O., De Simoni, M., Brewer, J., Bushell, T.J., Garside, P., and Carswell, H.V. (2010) Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain. British Journal of Pharmacology, 159(4), pp. 808-811. (doi:10.1111/j.1476-5381.2009.00527.x)

Conigliaro, P., Perricone, C., Benson, R.A., Garside, P., Brewer, J.M., Perricone, R., and Valesini, G. (2010) The type I IFN system in rheumatoid arthritis. Autoimmunity, 43(3), pp. 220-225. (doi:10.3109/08916930903510914)

Garside, P., and Brewer, J. (2010) In vivo imaging of infection immunology—4I’s! Seminars in Immunopathology, 32(3), pp. 289-296. (doi:10.1007/s00281-010-0215-y)

Rush, C.M., and Brewer, J.M. (2010) Tracking dendritic cells in vivo. Methods in Molecular Biology, 626, pp. 169-185. (doi:10.1007/978-1-60761-585-9_12)

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300)

Rush, C.M., Millington, O.R., Hutchison, S., Bryson, K., Brewer, J.M., and Garside, P. (2009) Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128(4), pp. 463-471. (doi:10.1111/j.1365-2567.2009.03124.x)

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi:10.1016/j.imlet.2008.02.008)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122.

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328.

Millington, O.R., Gibson, V.B., Rush, C.M., Zinselmeyer, B.H., Phillips, R.S., Garside, P., and Brewer, J.M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathogens, 3(10), e143. (doi:10.1371/journal.ppat.0030143)

Trif, M., Roseanu, A., Brock, J.H., and Brewer, J.M. (2007) Designing lipid nanostructures for local delivery of biologically active macromolecules. Journal of Liposome Research, 17(3-4), pp. 237-248. (doi:10.1080/08982100701530027)

Millington, O.R., Di Lorenzo, C., Phillips, R., Garside, P., and Brewer, J.M. (2006) Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5(2), pp. 1-22. (doi:dx.doi.org/10.1186/jbiol34)

Brewer, J. (2006) (How) do aluminium adjuvants work? Immunology Letters, 102, pp. 10-15. (doi:10.1016/j.imlet.2005.08.002)

McDonald, F., Mohrs, M., and Brewer, J. (2006) Using bicistronic IL-4 reporter mice to identify IL-4 expressing cells following immunisation with aluminium adjuvant. Vaccine, 24, pp. 5393-5399. (doi:10.1016/j.vaccine.2006.03.049)

Schneider, H., Downey, J., Smith, A., Zinselmeyer, B., Rush, C., Brewer, J., Wei, B., Hogg, N., Garside, P., and Rudd, C. (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313, pp. 1972-1975. (doi:10.1126/science.1131078)

Smith, K., Garside, P., Mcneil, R., and Brewer, J. (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses. Vaccine, 24, pp. 3035-3043. (doi:10.1016/j.vaccine.2005.10.027)

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Grierson, A., Mitchell, P., Adams, C., Mowat, A., Brewer, J., Harnett, M., and Garside, P. (2005) Direct quantitation of T cell signaling by laser scanning cytometry. Journal of Immunological Methods, 301, pp. 140-153. (doi:10.1016/j.jim.2005.04.011)

Zinselmeyer, B. H. et al. (2005) In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201(11), pp. 1815-1823. (doi:10.1084/jem.20050203)

Zinselmeyer, B. et al. (2005) In situ characterization of CD4(+) T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201, pp. 1815-1823. (doi:10.1084/jem.20050203)

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156.

Brewer, J., Pollock, K., Tetley, L., and Russell, D. (2004) Vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles. Journal of Immunology, 173, pp. 6143-6150.

Maffia, P., Brewer, J., Gracie, J., Ianaro, A., Leung, B., Mitchell, P., Smith, K., McInnes, L., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance, to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173, pp. 151-156.

Smith, K., Brewer, J., Mowat, A., Ron, Y., and Garside, P. (2004) The influence of follicular migration on T-cell differentiation. Immunology, 111, pp. 248-251. (doi:10.1111/j.1365-2567.2004.01813.x)

Smith, K., Brewer, J., Rush, C., Riley, J., and Garside, P. (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173, pp. 1640-1646.

Wei, X., Niedbala, W., Xu, D., Luo, Z., Pollock, K., and Brewer, J. (2004) Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection. Immunology Letters, 94, pp. 35-37. (doi:10.1016/j.imlet.2004.04.001)

Pollock, K., Conacher, M., Wei, X., Alexander, J., and Brewer, J. (2003) Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12. Immunology, 108, pp. 137-143.

Pollock, K., Mcneil, K., Mottram, J., Lyons, R., Brewer, J., Scott, P., Coombs, G., and Alexander, J. (2003) The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses. Journal of Immunology, 170, pp. 1746-1753.

Smith, K., Brewer, J., Webb, P., Coyle, A., Gutierrez-Ramos, C., and Garside, P. (2003) Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Journal of Immunology, 170, pp. 2310-2315.

Sun, H., Pollock, K., and Brewer, J. (2003) Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro. Vaccine, 21, pp. 849-855.

Leung, B., Conacher, M., Hunter, D., McInnes, I., Liew, F., and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077.

Conacher, M., Alexander, J., and Brewer, J. (2001) Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes). Vaccine, 19, pp. 2965-2974.

Trif, M., Guillen, C., Vaughan, D.M., Telfer, J.M., Brewer, J.M., Roseanu, A., and Brock, J.M. (2001) Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases. Experimental Biology and Medicine, 226(6), pp. 559-564.

Book Sections

Millington, O. R., Brewer, J. M., Garside, P., and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. In: Marelli-Berg, F. M. and Nourshargh, S. (eds.) T-Cell Trafficking: Methods and Protocols. Series: Methods in Molecular Biology, 616 (616). Humana Press Inc, pp. 193-206. ISBN 9781607614609 (doi:10.1007/978-1-60761-461-6_13)

Conference Proceedings

Elmesmari, A., Gilchrist, D., Fraser, A., Brewer, J., McInnes, I., and Kurowska-Stolarska, M. (2012) The role of miR-155 in monocyte migration in Rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, pp. 588-589. (doi:10.1111/imm.12002)

Elmesmari, A., Gilchrist, D. S., Fraser, A. D., Vaughan, D., McQueenie, R., Graham, G., Brewer, J., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Microrna-155 regulates chemokines and chemokine receptors in Rheumatoid Arthritis monocyte. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S384. (doi:10.1002/art.37735)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

This list was generated on Sat Jul 4 14:31:13 2015 BST.