Dr Edward Hutchinson

  • Senior Lecturer (Virology)

Biography

I started working on the molecular biology of influenza viruses as a graduate student with Paul Digard at the University of Cambridge. In 2009 I moved to the University of Oxford to work on influenza with Ervin Fodor, as a postdoctoral researcher at the Sir William Dunn School of Pathology and a Junior Research Fellow at Worcester College (2010-2014), and in 2016 I set up a research group at the MRC-University of Glasgow Centre for Virus Research.

Research interests

CVR Logo 1

Research Interests

I am interested in the proteins influenza viruses use to infect a host cell. My work aims to identify which viral and host proteins are important in establishing influenza infections, what they do, and how their functions can be regulated. 

These are very basic aspects of influenza virus molecular biology, but despite their small size influenza viruses are more complicated than they first appear. Their tiny genomes encode a remarkable diversity of gene products, many of which are recently-discovered and poorly-described. They replicate by taking control of and subverting highly complex cellular processes. And they propagate as a complex mixture of particles, some of which rely on each other to function.

To tackle this my group uses a range of methods, including virology, molecular biology, mass spectrometry, advanced imaging and structural biology. Furter details about our research projects can be found on the Hutchinson group page.

Disclosures

I have received honoraria for work in a steering group of the Centre for Open Science (Open Practices in Influenza Research; 2021-2022) and on an advisory board for Seqirus (2022). I have unpaid positions on the board of the European Scientific Working group on Influenza and other respiratory viruses (ESWI) and as a scientific adviser to PinPoint Medical.

Further information

Pages at ORCID, Google Scholar, ResearchGate, Publons and LinkedIn.

Publications

Selected publications

Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)

Sims, A. et al. (2023) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)

Hawksworth, A., Jayachander, M., Hester, S., Mohammed, S. and Hutchinson, E. (2020) Proteomics as a tool for live attenuated influenza vaccine characterisation. Vaccine, 38(4), pp. 868-877. (doi: 10.1016/j.vaccine.2019.10.082) (PMID:31708181)

Slater, A., Nair, N., Suétt, R., Mac Donnchadha, R., Bamford, C., Jasim, S., Livingstone, D. and Hutchinson, E. (2022) Visualising viruses. Journal of General Virology, 103(1), 001730. (doi: 10.1099/jgv.0.001730) (PMID:35082014) (PMCID:PMC8895616)

All publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008
Number of items: 40.

2024

Bentley-Abbot, C., Heslop, R., Pirillo, C., Chandrasegaran, P., McConnell, G., Roberts, E. , Hutchinson, E. and MacLeod, A. (2024) An easy to use tool for the analysis of subcellular mRNA transcript colocalisation in smFISH data. Scientific Reports, 14, 8348. (doi: 10.1038/s41598-024-58641-3) (PMID:38594373) (PMCID:PMC11004122)

Ranum, J. N. et al. (2024) Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome. Nucleic Acids Research, (doi: 10.1093/nar/gkae133) (PMID:38407436) (Early Online Publication)

2023

Wallace, S. et al. (2023) Multiplexed biosensing of proteins and virions with disposable plasmonic assays. ACS Sensors, 8(9), pp. 3338-3348. (doi: 10.1021/acssensors.2c02238) (PMID:37610841) (PMCID:PMC10521139)

Pirillo, C. et al. (2023) Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation. Science Immunology, 8(85), eadg8249. (doi: 10.1126/sciimmunol.adg8249) (PMID:37478193)

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. mSphere, 8(2), e0003423. (doi: 10.1128/msphere.00034-23) (PMID:36700653) (PMCID:PMC10117089)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. Journal of Virology, 97(2), e0008923. (doi: 10.1128/jvi.00089-23) (PMID:36700640) (PMCID:PMC9972907)

Cable, J. et al. (2023) Respiratory viruses: new frontiers—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1522(1), pp. 60-73. (doi: 10.1111/nyas.14958) (PMID:36722473)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. mBio, 14, e00188-23. (doi: 10.1128/mbio.00188-23) (PMID:36700642) (PMCID:PMC9973315)

Sims, A. et al. (2023) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)

Iannucci, S., Harvey, W. T., Hughes, J. , Robertson, D. L. , Poyade, M. and Hutchinson, E. (2023) The SARS-CoV-2 Spike Protein Mutation Explorer: using an interactive application to improve the public understanding of SARS-CoV-2 variants of concern. Journal of Visual Communication in Medicine, 46(3), pp. 122-132. (doi: 10.1080/17453054.2023.2237087) (PMID:37526402) (PMCID:PMC10726978)

2022

Iannucci, S., Harvey, W., Hughes, J. , Robertson, D. L. , Hutchinson, E. and Poyade, M. (2022) Using molecular visualisation techniques to explain the molecular biology of SARS-CoV-2 spike protein mutations to a general audience. In: Shapiro, L. and Rea, P. M. (eds.) Biomedical Visualisation. Volume 12. Series: Advances in experimental medicine and biology (1388). Springer: Cham, pp. 129-152. ISBN 9783031108884 (doi: 10.1007/978-3-031-10889-1_6)

Slater, A., Nair, N., Suétt, R., Mac Donnchadha, R., Bamford, C., Jasim, S., Livingstone, D. and Hutchinson, E. (2022) Visualising viruses. Journal of General Virology, 103(1), 001730. (doi: 10.1099/jgv.0.001730) (PMID:35082014) (PMCID:PMC8895616)

2021

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Gestuveo, R. J., Royle, J., Donald, C. L. , Lamont, D. J., Hutchinson, E. C. , Merits, A., Kohl, A. and Varjak, M. (2021) Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection. Nature Communications, 12, 2766. (doi: 10.1038/s41467-021-22966-8) (PMID:33986255) (PMCID:PMC8119459)

2020

Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)

Hawksworth, A., Jayachander, M., Hester, S., Mohammed, S. and Hutchinson, E. (2020) Proteomics as a tool for live attenuated influenza vaccine characterisation. Vaccine, 38(4), pp. 868-877. (doi: 10.1016/j.vaccine.2019.10.082) (PMID:31708181)

2019

Hirst, J. C. and Hutchinson, E. C. (2019) Single-particle measurements of filamentous influenza virions reveal damage induced by freezing. Journal of General Virology, 100(12), pp. 1631-1640. (doi: 10.1099/jgv.0.001330) (PMID:31553305) (PMCID:PMC6904231)

Burke, A., Hirst, J. C. and Hutchinson, E. C. (2019) Altering the Size Distribution of Influenza Virion Populations [Poster]. Microbiology Society Annual Conference, Belfast, UK, 8-11 Apr 2019. (doi: 10.1099/acmi.ac2019.po0122)

Hirst, J. C., Burke, A. and Hutchinson, E. C. (2019) Single-particle Measurements Reveal Damage to Filamentous Influenza Virions During Laboratory Handling [Poster]. Microbiology Society Annual Conference, Belfast, UK, 8-11 Apr 2019. (doi: 10.1099/acmi.ac2019.po0292)

Lakdawala, S., Nair, N. and Hutchinson, E. (2019) Educational material about influenza viruses. Viruses, 11(3), 231. (doi: 10.3390/v11030231) (PMID:30866478) (PMCID:PMC6466267)

2018

Bottermann, M. et al. (2018) TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination. Proceedings of the National Academy of Sciences of the United States of America, 115(41), pp. 10440-10445. (doi: 10.1073/pnas.1806314115) (PMID:30209217) (PMCID:PMC6187179)

Hutchinson, E. C. (2018) Influenza virus. Trends in Microbiology, 26(9), pp. 809-810. (doi: 10.1016/j.tim.2018.05.013) (PMID:29909041)

Hutchinson, E. C. and Stegmann, M. (2018) Purification and proteomics of influenza virions. In: Yamauchi, Y. (ed.) Influenza Virus. Series: Methods in molecular biology (1836). Humana Press: New York, NY, pp. 89-120. ISBN 9781493986774 (doi: 10.1007/978-1-4939-8678-1_5)

Hutchinson, E. C. and Yamauchi, Y. (2018) Understanding influenza. In: Yamauchi, Y. (ed.) Influenza Virus. Series: Methods in molecular biology (1836). Humana Press: New York, NY, pp. 1-21. ISBN 9781493986774 (doi: 10.1007/978-1-4939-8678-1_1)

2016

Dadonaite, B., Vijayakrishnan, S. , Fodor, E., Bhella, D. and Hutchinson, E. C. (2016) Filamentous influenza viruses. Journal of General Virology, 97(8), pp. 1755-1764. (doi: 10.1099/jgv.0.000535) (PMID:27365089)

van Wilgenburg, B. et al. (2016) MAIT cells are activated during human viral infections. Nature Communications, 7, 11653. (doi: 10.1038/ncomms11653) (PMID:27337592) (PMCID:PMC4931007)

2015

Hutchinson, E. C. , Charles, P. D., Hester, S. S., Thomas, B., Trudgian, D., Martínez-Alonso, M. and Fodor, E. (2015) Erratum: Conserved and host-specific features of influenza virion architecture. Nature Communications, 6, 6446. (doi: 10.1038/ncomms7446) (PMID:25687574)

Turrell, L., Hutchinson, E. C. , Vreede, F. T. and Fodor, E. (2015) Regulation of influenza A virus nucleoprotein oligomerization by phosphorylation. Journal of Virology, 89(2), pp. 1452-1455. (doi: 10.1128/JVI.02332-14) (PMID:25355893) (PMCID:PMC4300657)

2014

York, A., Hutchinson, E. C. and Fodor, E. (2014) Interactome analysis of the influenza a virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication. Journal of Virology, 88(22), pp. 13284-13299. (doi: 10.1128/JVI.01813-14) (PMID:25187537) (PMCID:PMC4249064)

Hutchinson, E. C. , Charles, P. D., Hester, S. S., Thomas, B., Trudgian, D., Martínez-Alonso, M. and Fodor, E. (2014) Conserved and host-specific features of influenza virion architecture. Nature Communications, 5, 4816. (doi: 10.1038/ncomms5816) (PMID:25226414) (PMCID:PMC4167602)

2013

Hutchinson, E. C. and Fodor, E. (2013) Transport of the influenza virus genome from nucleus to nucleus. Viruses, 5(10), pp. 2424-2446. (doi: 10.3390/v5102424) (PMID:24104053) (PMCID:PMC3814596)

2012

Hutchinson, E.C. and Fodor, E. (2012) Nuclear import of the influenza A virus transcriptional machinery. Vaccine, 30(51), pp. 7353-7358. (doi: 10.1016/j.vaccine.2012.04.085) (PMID:22652398)

Hutchinson, E. C. , Denham, E. M., Thomas, B., Trudgian, D. C., Hester, S. S., Ridlova, G., York, A., Turrell, L. and Fodor, E. (2012) Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry. PLoS Pathogens, 8(11), e1002993. (doi: 10.1371/journal.ppat.1002993) (PMID:23144613) (PMCID:PMC3493474)

Wise, H. M. et al. (2012) Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain. PLoS Pathogens, 8(11), e1002998. (doi: 10.1371/journal.ppat.1002998) (PMID:23133386) (PMCID:23133386)

2011

Hutchinson, E.C. , Orr, O.E., Man Liu, S., Engelhardt, O.G. and Fodor, E. (2011) Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5. Journal of General Virology, 92(8), pp. 1859-1869. (doi: 10.1099/vir.0.032813-0) (PMID:21562121)

2010

Hutchinson, E.C. , von Kirchbach, J.C., Gog, J.R. and Digard, P. (2010) Genome packaging in influenza A virus. Journal of General Virology, 91(2), pp. 313-328. (doi: 10.1099/vir.0.017608-0) (PMID:19955561)

2009

Hutchinson, E. C. , Wise, H. M., Kudryavtseva, K., Curran, M. D. and Digard, P. (2009) Characterisation of influenza A viruses with mutations in segment 5 packaging signals. Vaccine, 27(45), pp. 6270-6275. (doi: 10.1016/j.vaccine.2009.05.053) (PMID:19840659) (PMCID:19840659)

Noton, S.L., Simpson-Holley, M., Medcalf, E., Wise, H.M., Hutchinson, E.C. , McCauley, J.W. and Digard, P. (2009) Studies of an influenza A virus temperature-sensitive mutant identify a late role for NP in the formation of infectious virions. Journal of Virology, 83(2), pp. 562-571. (doi: 10.1128/JVI.01424-08) (PMID:18987140) (PMCID:PMC2612366)

2008

Hutchinson, E.C. , Curran, M.D., Read, E.K., Gog, J.R. and Digard, P. (2008) Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. Journal of Virology, 82(23), pp. 11869-11879. (doi: 10.1128/JVI.01634-08) (PMID:18815307) (PMCID:PMC2583641)

This list was generated on Fri Apr 19 15:13:54 2024 BST.
Jump to: Articles | Book Sections | Conference or Workshop Item
Number of items: 40.

Articles

Bentley-Abbot, C., Heslop, R., Pirillo, C., Chandrasegaran, P., McConnell, G., Roberts, E. , Hutchinson, E. and MacLeod, A. (2024) An easy to use tool for the analysis of subcellular mRNA transcript colocalisation in smFISH data. Scientific Reports, 14, 8348. (doi: 10.1038/s41598-024-58641-3) (PMID:38594373) (PMCID:PMC11004122)

Ranum, J. N. et al. (2024) Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome. Nucleic Acids Research, (doi: 10.1093/nar/gkae133) (PMID:38407436) (Early Online Publication)

Wallace, S. et al. (2023) Multiplexed biosensing of proteins and virions with disposable plasmonic assays. ACS Sensors, 8(9), pp. 3338-3348. (doi: 10.1021/acssensors.2c02238) (PMID:37610841) (PMCID:PMC10521139)

Pirillo, C. et al. (2023) Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation. Science Immunology, 8(85), eadg8249. (doi: 10.1126/sciimmunol.adg8249) (PMID:37478193)

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. mSphere, 8(2), e0003423. (doi: 10.1128/msphere.00034-23) (PMID:36700653) (PMCID:PMC10117089)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. Journal of Virology, 97(2), e0008923. (doi: 10.1128/jvi.00089-23) (PMID:36700640) (PMCID:PMC9972907)

Cable, J. et al. (2023) Respiratory viruses: new frontiers—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1522(1), pp. 60-73. (doi: 10.1111/nyas.14958) (PMID:36722473)

Goodrum, F. et al. (2023) Virology under the microscope—a call for rational discourse. mBio, 14, e00188-23. (doi: 10.1128/mbio.00188-23) (PMID:36700642) (PMCID:PMC9973315)

Sims, A. et al. (2023) Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biology, 21(2), e3001941. (doi: 10.1371/journal.pbio.3001941) (PMID:36757937) (PMCID:PMC9910727)

Iannucci, S., Harvey, W. T., Hughes, J. , Robertson, D. L. , Poyade, M. and Hutchinson, E. (2023) The SARS-CoV-2 Spike Protein Mutation Explorer: using an interactive application to improve the public understanding of SARS-CoV-2 variants of concern. Journal of Visual Communication in Medicine, 46(3), pp. 122-132. (doi: 10.1080/17453054.2023.2237087) (PMID:37526402) (PMCID:PMC10726978)

Slater, A., Nair, N., Suétt, R., Mac Donnchadha, R., Bamford, C., Jasim, S., Livingstone, D. and Hutchinson, E. (2022) Visualising viruses. Journal of General Virology, 103(1), 001730. (doi: 10.1099/jgv.0.001730) (PMID:35082014) (PMCID:PMC8895616)

Charman, M. et al. (2021) Constitutive TRIM22 expression in the respiratory tract confers a pre-existing defence against influenza A virus infection. Frontiers in Cellular and Infection Microbiology, 11, 689707. (doi: 10.3389/fcimb.2021.689707) (PMID:34621686) (PMCID:PMC8490869)

Gestuveo, R. J., Royle, J., Donald, C. L. , Lamont, D. J., Hutchinson, E. C. , Merits, A., Kohl, A. and Varjak, M. (2021) Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection. Nature Communications, 12, 2766. (doi: 10.1038/s41467-021-22966-8) (PMID:33986255) (PMCID:PMC8119459)

Sook Yuin Ho, J. et al. (2020) Hybrid gene origination creates human-virus chimeric proteins during infection. Cell, 181(7), 1502-1517.e23. (doi: 10.1016/j.cell.2020.05.035) (PMID:32559462) (PMCID:PMC7323901)

Hawksworth, A., Jayachander, M., Hester, S., Mohammed, S. and Hutchinson, E. (2020) Proteomics as a tool for live attenuated influenza vaccine characterisation. Vaccine, 38(4), pp. 868-877. (doi: 10.1016/j.vaccine.2019.10.082) (PMID:31708181)

Hirst, J. C. and Hutchinson, E. C. (2019) Single-particle measurements of filamentous influenza virions reveal damage induced by freezing. Journal of General Virology, 100(12), pp. 1631-1640. (doi: 10.1099/jgv.0.001330) (PMID:31553305) (PMCID:PMC6904231)

Lakdawala, S., Nair, N. and Hutchinson, E. (2019) Educational material about influenza viruses. Viruses, 11(3), 231. (doi: 10.3390/v11030231) (PMID:30866478) (PMCID:PMC6466267)

Bottermann, M. et al. (2018) TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination. Proceedings of the National Academy of Sciences of the United States of America, 115(41), pp. 10440-10445. (doi: 10.1073/pnas.1806314115) (PMID:30209217) (PMCID:PMC6187179)

Hutchinson, E. C. (2018) Influenza virus. Trends in Microbiology, 26(9), pp. 809-810. (doi: 10.1016/j.tim.2018.05.013) (PMID:29909041)

Dadonaite, B., Vijayakrishnan, S. , Fodor, E., Bhella, D. and Hutchinson, E. C. (2016) Filamentous influenza viruses. Journal of General Virology, 97(8), pp. 1755-1764. (doi: 10.1099/jgv.0.000535) (PMID:27365089)

van Wilgenburg, B. et al. (2016) MAIT cells are activated during human viral infections. Nature Communications, 7, 11653. (doi: 10.1038/ncomms11653) (PMID:27337592) (PMCID:PMC4931007)

Hutchinson, E. C. , Charles, P. D., Hester, S. S., Thomas, B., Trudgian, D., Martínez-Alonso, M. and Fodor, E. (2015) Erratum: Conserved and host-specific features of influenza virion architecture. Nature Communications, 6, 6446. (doi: 10.1038/ncomms7446) (PMID:25687574)

Turrell, L., Hutchinson, E. C. , Vreede, F. T. and Fodor, E. (2015) Regulation of influenza A virus nucleoprotein oligomerization by phosphorylation. Journal of Virology, 89(2), pp. 1452-1455. (doi: 10.1128/JVI.02332-14) (PMID:25355893) (PMCID:PMC4300657)

York, A., Hutchinson, E. C. and Fodor, E. (2014) Interactome analysis of the influenza a virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication. Journal of Virology, 88(22), pp. 13284-13299. (doi: 10.1128/JVI.01813-14) (PMID:25187537) (PMCID:PMC4249064)

Hutchinson, E. C. , Charles, P. D., Hester, S. S., Thomas, B., Trudgian, D., Martínez-Alonso, M. and Fodor, E. (2014) Conserved and host-specific features of influenza virion architecture. Nature Communications, 5, 4816. (doi: 10.1038/ncomms5816) (PMID:25226414) (PMCID:PMC4167602)

Hutchinson, E. C. and Fodor, E. (2013) Transport of the influenza virus genome from nucleus to nucleus. Viruses, 5(10), pp. 2424-2446. (doi: 10.3390/v5102424) (PMID:24104053) (PMCID:PMC3814596)

Hutchinson, E.C. and Fodor, E. (2012) Nuclear import of the influenza A virus transcriptional machinery. Vaccine, 30(51), pp. 7353-7358. (doi: 10.1016/j.vaccine.2012.04.085) (PMID:22652398)

Hutchinson, E. C. , Denham, E. M., Thomas, B., Trudgian, D. C., Hester, S. S., Ridlova, G., York, A., Turrell, L. and Fodor, E. (2012) Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry. PLoS Pathogens, 8(11), e1002993. (doi: 10.1371/journal.ppat.1002993) (PMID:23144613) (PMCID:PMC3493474)

Wise, H. M. et al. (2012) Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain. PLoS Pathogens, 8(11), e1002998. (doi: 10.1371/journal.ppat.1002998) (PMID:23133386) (PMCID:23133386)

Hutchinson, E.C. , Orr, O.E., Man Liu, S., Engelhardt, O.G. and Fodor, E. (2011) Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5. Journal of General Virology, 92(8), pp. 1859-1869. (doi: 10.1099/vir.0.032813-0) (PMID:21562121)

Hutchinson, E.C. , von Kirchbach, J.C., Gog, J.R. and Digard, P. (2010) Genome packaging in influenza A virus. Journal of General Virology, 91(2), pp. 313-328. (doi: 10.1099/vir.0.017608-0) (PMID:19955561)

Hutchinson, E. C. , Wise, H. M., Kudryavtseva, K., Curran, M. D. and Digard, P. (2009) Characterisation of influenza A viruses with mutations in segment 5 packaging signals. Vaccine, 27(45), pp. 6270-6275. (doi: 10.1016/j.vaccine.2009.05.053) (PMID:19840659) (PMCID:19840659)

Noton, S.L., Simpson-Holley, M., Medcalf, E., Wise, H.M., Hutchinson, E.C. , McCauley, J.W. and Digard, P. (2009) Studies of an influenza A virus temperature-sensitive mutant identify a late role for NP in the formation of infectious virions. Journal of Virology, 83(2), pp. 562-571. (doi: 10.1128/JVI.01424-08) (PMID:18987140) (PMCID:PMC2612366)

Hutchinson, E.C. , Curran, M.D., Read, E.K., Gog, J.R. and Digard, P. (2008) Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. Journal of Virology, 82(23), pp. 11869-11879. (doi: 10.1128/JVI.01634-08) (PMID:18815307) (PMCID:PMC2583641)

Book Sections

Iannucci, S., Harvey, W., Hughes, J. , Robertson, D. L. , Hutchinson, E. and Poyade, M. (2022) Using molecular visualisation techniques to explain the molecular biology of SARS-CoV-2 spike protein mutations to a general audience. In: Shapiro, L. and Rea, P. M. (eds.) Biomedical Visualisation. Volume 12. Series: Advances in experimental medicine and biology (1388). Springer: Cham, pp. 129-152. ISBN 9783031108884 (doi: 10.1007/978-3-031-10889-1_6)

Hutchinson, E. C. and Stegmann, M. (2018) Purification and proteomics of influenza virions. In: Yamauchi, Y. (ed.) Influenza Virus. Series: Methods in molecular biology (1836). Humana Press: New York, NY, pp. 89-120. ISBN 9781493986774 (doi: 10.1007/978-1-4939-8678-1_5)

Hutchinson, E. C. and Yamauchi, Y. (2018) Understanding influenza. In: Yamauchi, Y. (ed.) Influenza Virus. Series: Methods in molecular biology (1836). Humana Press: New York, NY, pp. 1-21. ISBN 9781493986774 (doi: 10.1007/978-1-4939-8678-1_1)

Conference or Workshop Item

Burke, A., Hirst, J. C. and Hutchinson, E. C. (2019) Altering the Size Distribution of Influenza Virion Populations [Poster]. Microbiology Society Annual Conference, Belfast, UK, 8-11 Apr 2019. (doi: 10.1099/acmi.ac2019.po0122)

Hirst, J. C., Burke, A. and Hutchinson, E. C. (2019) Single-particle Measurements Reveal Damage to Filamentous Influenza Virions During Laboratory Handling [Poster]. Microbiology Society Annual Conference, Belfast, UK, 8-11 Apr 2019. (doi: 10.1099/acmi.ac2019.po0292)

This list was generated on Fri Apr 19 15:13:54 2024 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Virus Dashboards: Preparing for Pandemics
    Medical Research Council
    2023 - 2024
     
  • Virus Dashboards: Preparing for Pandemics
    Arts and Humanities Research Council
    2023 - 2024
     
  • Disposable plasmonics assays for monitoring airborne pathogens in commercial air filters
    Engineering and Physical Sciences Research Council
    2022 - 2023
     
  • The Influenza Virus Toolkit: a reagent sharing resource for influenza research
    Medical Research Council
    2022 - 2023
     
  • MRC Transition Support Award CDA
    Medical Research Council
    2021 - 2023
     
  • Evaluating the Feasibility of a Multi Respiratory Virus Diagnostic using Chiral Plasmonic Assays
    Wellcome Trust
    2021 - 2021
     
  • Functional investigations of the influenza virus proteome
    Medical Research Council
    2016 - 2023
     
  • Quinquennial Core Funds
    Medical Research Council
    2016 - 2021
     

Supervision

  • Sims, Anna
    Respiratory Virus Coinfection and Superinfection Exclusion

Teaching

Level 3 Microbiology: Deputy Co-ordinator

Level 4 Molecular and Cellular Microbiology: Organising Committee

Wellcome Trust Integrative Infection Biology Doctoral Training Programme: Management Group

CVR Introduction to Virus Research: Organising Committee (chair)

Deputy Convenor of Postgraduate Research, School of Infection & Immunity

Professional activities & recognition

Prizes, awards & distinctions

  • 2021: Microbiology Outreach Prize (Microbiology Society)
  • 2008: New Researcher Science Communication Award (Biosciences Federation)
  • 2007: Young Microbiologist of the Year (Society for General Microbiology)

Research fellowships

  • 2021 - 2023: MRC Transition Support Award
  • 2016 - 2021: MRC Career Development Award
  • 2010 - 2014: Junior Research Fellowship, Worcester College Oxford

Grant committees & research advisory boards

  • 2018 - 2026: BBSRC, Pool of Experts
  • 2024 - 2026: Royal Society, Research Grants Board: Biological Sciences
  • 2020 - 2021: Wellcome Trust, Covid19 Protein Production Consortium, Reviewer Pool
  • 2021 - 2022: Center for Open Science, Open Practices in Influenza Research

Editorial boards

  • 2023 - 2026: Journal of General Virology (Board of Reviewers)

Professional & learned societies

  • 2015: Board Member, European Scientific Working Group on Influenza
  • 2019 - 2023: Virus Division (Member), Microbiology Society
  • 2024 - 2025: Virus Division (Chair-Elect), Microbiology Society
  • 2022 - 2025: Global Partnerships and Advocacy Committee (Advocacy subcommittee), American Society for Virology

Research datasets

Jump to: 2021 | 2019 | 2018
Number of items: 5.

2021

Slater, A., Nair, N., Suétt, R., Mac Donnchadha, R., Bamford, C., Jasim, S., Livingstone, D. and Hutchinson, E. (2021) Visualising Viruses. [Data Collection]

Syme, C. , Bhella, D. and Hutchinson, E. (2021) A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding. [Data Collection]

Goldfarb, D. M., Piras, I., Bone, J., Amat, J., Parrish, C., Bhella, D. , Hutchinson, E. and Murcia, P. (2021) Identification of previously unknown genetic determinants of influenza A virus morphology. [Data Collection]

2019

Hirst, J. and Hutchinson, E. (2019) Single-particle measurements of filamentous influenza virions reveal damage induced by freezing. [Data Collection]

2018

Hawksworth, A., Jayachander, M., Hester, S., Mohammed, S. and Hutchinson, E. (2018) Proteomics as a tool for Live Attenuated Influenza Vaccine characterisation. [Data Collection]

This list was generated on Fri Apr 19 15:13:56 2024 BST.

Ed Hutchinson Dec 2017

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