- Professor of Parasite Cell Biology (Parasitology)
- Associate Academic (School of Veterinary Medicine)
Research in the Shiels laboratory is centered on parasites transmitted by ticks that cause important disease in livestock and are a great threat to production systems in many parts of the world. Theileria parasites can cause lymphoproliferative/neoplastic type disorders in cattle and small ruminants. They are of interest with respect to understanding parasite-host interactions at the molecular level and changes to cellular control associated with cancer and inflammatory disease. In addition, current control measures have limitations and novel control strategies are required against Theileria and other related parasites, such as Babesia and Plasmodium. Current research includes investigation of how Theileria parasites activate and modulate the host leukocyte and investigation of strategies that prevent transmission of the parasite via the tick vector.